JP2018502583A5 - - Google Patents
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- JP2018502583A5 JP2018502583A5 JP2017536779A JP2017536779A JP2018502583A5 JP 2018502583 A5 JP2018502583 A5 JP 2018502583A5 JP 2017536779 A JP2017536779 A JP 2017536779A JP 2017536779 A JP2017536779 A JP 2017536779A JP 2018502583 A5 JP2018502583 A5 JP 2018502583A5
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- JP
- Japan
- Prior art keywords
- variant
- gene
- polynucleotide
- seq
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562102569P | 2015-01-12 | 2015-01-12 | |
| US62/102,569 | 2015-01-12 | ||
| PCT/US2016/013109 WO2016115177A1 (en) | 2015-01-12 | 2016-01-12 | Modified hepatitis post-transcriptional regulatory elements |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018502583A JP2018502583A (ja) | 2018-02-01 |
| JP2018502583A5 true JP2018502583A5 (https=) | 2019-02-21 |
| JP6868560B2 JP6868560B2 (ja) | 2021-05-12 |
Family
ID=55310922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017536779A Active JP6868560B2 (ja) | 2015-01-12 | 2016-01-12 | 修飾された肝炎転写後調節エレメント |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10363269B2 (https=) |
| EP (1) | EP3245292B1 (https=) |
| JP (1) | JP6868560B2 (https=) |
| KR (1) | KR102554374B1 (https=) |
| CN (1) | CN107429260B (https=) |
| AU (1) | AU2016206868B2 (https=) |
| BR (1) | BR112017014917A2 (https=) |
| CA (1) | CA2973483A1 (https=) |
| ES (1) | ES2877367T3 (https=) |
| IL (1) | IL253399B2 (https=) |
| MA (1) | MA41346A (https=) |
| MX (1) | MX391694B (https=) |
| MY (1) | MY187559A (https=) |
| RU (1) | RU2734594C2 (https=) |
| SA (1) | SA517381912B1 (https=) |
| SG (1) | SG11201705692SA (https=) |
| WO (1) | WO2016115177A1 (https=) |
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| ES2987570T3 (es) | 2014-11-05 | 2024-11-15 | Juno Therapeutics Inc | Métodos para la transducción y el procesamiento de células |
| WO2017024318A1 (en) | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| HUE055862T2 (hu) | 2016-04-20 | 2021-12-28 | Centro De Investig Energeticas | Készítmények és eljárások PKLR fokozott génexpressziójára |
| KR102712926B1 (ko) | 2016-10-20 | 2024-10-07 | 상가모 테라퓨틱스, 인코포레이티드 | 파브리병의 치료를 위한 방법 및 조성물 |
| CN107058315B (zh) * | 2016-12-08 | 2019-11-08 | 上海优卡迪生物医药科技有限公司 | 敲减人PD-1的siRNA、重组表达CAR-T载体及其构建方法和应用 |
| JP7227912B2 (ja) * | 2017-02-08 | 2023-02-24 | ダナ－ファーバー キャンサー インスティテュート，インコーポレイテッド | キメラ抗原受容体の調節 |
| WO2019028273A1 (en) * | 2017-08-02 | 2019-02-07 | Dna2.0, Inc. Dba Atum | DNA VECTORS AND ELEMENTS FOR SUSTAINED GENE EXPRESSION IN EUKARYOTIC CELLS |
| KR20260026092A (ko) | 2017-09-19 | 2026-02-25 | 메사추세츠 인스티튜트 오브 테크놀로지 | 키메라 항원 수용체 t 세포 요법을 위한 조성물 및 그의 용도 |
| SG11202002263TA (en) | 2017-10-16 | 2020-04-29 | Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas | Lentiviral vectors for delivery of pklr to treat pyruvate kinase deficiency |
| WO2019200167A1 (en) | 2018-04-11 | 2019-10-17 | Rocket Pharmaceuticals, Ltd. | Compositions and methods for stem cell transplant |
| MX2020011386A (es) | 2018-04-27 | 2021-01-29 | Spacecraft Seven Llc | Terapia genica para la degeneracion del snc. |
| AU2019346335B2 (en) | 2018-09-28 | 2024-07-25 | Massachusetts Institute Of Technology | Collagen-localized immunomodulatory molecules and methods thereof |
| WO2020210630A1 (en) | 2019-04-12 | 2020-10-15 | C4 Therapeutics, Inc. | Tricyclic degraders of ikaros and aiolos |
| CN111825769B (zh) * | 2019-04-16 | 2022-03-25 | 上海科技大学 | 一种泛素化缺失的嵌合抗原受体及其用途 |
| CN114207135A (zh) | 2019-06-11 | 2022-03-18 | 夏尔人类遗传性治疗公司 | 用于治疗由失调的血浆激肽释放酶介导的疾病的抗体的腺相关病毒载体递送 |
| WO2020263399A1 (en) | 2019-06-26 | 2020-12-30 | Massachusetts Institute Of Technology | Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof |
| WO2021061648A1 (en) | 2019-09-23 | 2021-04-01 | Massachusetts Institute Of Technology | Methods and compositions for stimulation of endogenous t cell responses |
| WO2021081280A1 (en) | 2019-10-23 | 2021-04-29 | Shire Human Genetic Therapies, Inc. | Adeno-associated virus vectors based gene therapy for hereditary angioedema |
| JP2023517063A (ja) | 2020-03-10 | 2023-04-21 | マサチューセッツ インスティテュート オブ テクノロジー | 操作されたメモリー様ｎｋ細胞を作製するための方法およびその組成物 |
| BR112022017924A2 (pt) | 2020-03-10 | 2022-12-20 | Massachusetts Inst Technology | Composições e métodos para imunoterapia de câncer npm1c-positivo |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| DE102020106710A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| US20230183747A1 (en) | 2020-04-27 | 2023-06-15 | Juno Therapeutics, Inc. | Stabilization of polyethyleneimine-deoxyribonucleic acid complex size and activity |
| US20210340524A1 (en) | 2020-05-01 | 2021-11-04 | Massachusetts Institute Of Technology | Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof |
| US12433954B2 (en) | 2020-05-01 | 2025-10-07 | Massachusetts Institute Of Technology | Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs |
| EP4165196A1 (en) * | 2020-06-11 | 2023-04-19 | Sangamo Therapeutics, Inc. | Methods and compositions for expressing phenylalanine hydroxylase |
| MX2023000124A (es) * | 2020-06-30 | 2023-03-08 | Univ Court Univ Of Edinburgh | Sistema de expresion de transgenes. |
| KR20230043869A (ko) | 2020-08-07 | 2023-03-31 | 스페이스크래프트 세븐, 엘엘씨 | Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법 |
| KR20220035693A (ko) * | 2020-09-14 | 2022-03-22 | 주식회사 제너로스 | 표적화된 유전자 전달을 위한 아데노-부속 바이러스 벡터 |
| JP2023543360A (ja) * | 2020-09-29 | 2023-10-13 | ニューエクセル・セラピューティクス・インコーポレイテッド | Ｄｌｘ２ベクター |
| WO2022130014A1 (en) | 2020-12-16 | 2022-06-23 | Takeda Pharmaceutical Company Limited | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| US20230049217A1 (en) * | 2021-05-21 | 2023-02-16 | Novartis Ag | Compositions and methods for enhancing visual function |
| US20260083848A1 (en) | 2021-11-03 | 2026-03-26 | Viracta Therapeutics, Inc. | Combination of car t-cell therapy with btk inhibitors and methods of use thereof |
| AU2022379949A1 (en) * | 2021-11-04 | 2024-05-02 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| AU2023304369A1 (en) | 2022-07-07 | 2025-01-16 | Science Corporation | Neural interface device |
| WO2024077052A1 (en) * | 2022-10-04 | 2024-04-11 | Emergent Product Development Gaithersburg Inc. | Novel vsv virus formulations |
| WO2024226858A1 (en) | 2023-04-26 | 2024-10-31 | Juno Therapeutics, Inc. | Methods for viral vector manufacturing |
| WO2026003067A1 (en) * | 2024-06-25 | 2026-01-02 | Asgard Therapeutics Ab | Transcription factors and reprogramming modulators for reprogramming cells to cdc1 cells, compositions and methods thereof |
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| US4452773A (en) | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
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| ES2987570T3 (es) | 2014-11-05 | 2024-11-15 | Juno Therapeutics Inc | Métodos para la transducción y el procesamiento de células |
-
2016
- 2016-01-11 MA MA041346A patent/MA41346A/fr unknown
- 2016-01-12 WO PCT/US2016/013109 patent/WO2016115177A1/en not_active Ceased
- 2016-01-12 CA CA2973483A patent/CA2973483A1/en active Pending
- 2016-01-12 CN CN201680015106.6A patent/CN107429260B/zh active Active
- 2016-01-12 SG SG11201705692SA patent/SG11201705692SA/en unknown
- 2016-01-12 ES ES16703392T patent/ES2877367T3/es active Active
- 2016-01-12 AU AU2016206868A patent/AU2016206868B2/en active Active
- 2016-01-12 US US14/994,114 patent/US10363269B2/en active Active
- 2016-01-12 MX MX2017009113A patent/MX391694B/es unknown
- 2016-01-12 MY MYPI2017001032A patent/MY187559A/en unknown
- 2016-01-12 RU RU2017126975A patent/RU2734594C2/ru active
- 2016-01-12 EP EP16703392.7A patent/EP3245292B1/en active Active
- 2016-01-12 BR BR112017014917A patent/BR112017014917A2/pt not_active Application Discontinuation
- 2016-01-12 KR KR1020177022738A patent/KR102554374B1/ko active Active
- 2016-01-12 JP JP2017536779A patent/JP6868560B2/ja active Active
-
2017
- 2017-07-10 IL IL253399A patent/IL253399B2/en unknown
- 2017-07-12 SA SA517381912A patent/SA517381912B1/ar unknown
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