|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JP2518911B2
(ja)
|
1987-10-23 |
1996-07-31 |
森永乳業株式会社 |
ｃ―ｆｍｓ癌原遺伝子の過剰発現によって特徴づけられた癌の処置用組成物および方法
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5866114A
(en)
|
1992-06-09 |
1999-02-02 |
Chiron Corporation |
Crystallization of M-CSFα
|
|
US20020193575A1
(en)
|
1993-09-07 |
2002-12-19 |
Smithkline Beecham P.L.C. |
Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
|
|
US6972323B1
(en)
|
1997-04-01 |
2005-12-06 |
Sankyo Company, Limited |
Anti-Fas antibodies
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
WO1999029345A1
(en)
|
1997-12-05 |
1999-06-17 |
La Jolla Institute For Experimental Medicine |
Inhibition of tumor growth by macrophage intervention
|
|
AU6366999A
(en)
|
1998-10-30 |
2000-05-22 |
Takeda Chemical Industries Ltd. |
Betacellulin protein-containing preparations
|
|
PT1223980E
(pt)
|
1999-10-28 |
2003-10-31 |
Reinhold Hofbauer |
Utilizacao de inibidores de csf-1
|
|
WO2001034177A2
(en)
|
1999-11-08 |
2001-05-17 |
The Government Of The United States Of America, A S Represented By The Secretary, Department Of Hea Lth & Human Services, The National Institutes Of Health |
Method of treating a viral infection using antagonists of macrophage colony stimulating factor
|
|
US7108852B2
(en)
|
2000-03-20 |
2006-09-19 |
Warner-Lambert Company Llc |
Methods of treating inflammation using antibodies to M-CSF
|
|
US7455836B2
(en)
|
2000-05-08 |
2008-11-25 |
The University Of Melbourne |
Method of treatment and agents useful for same
|
|
US6773895B2
(en)
|
2000-09-01 |
2004-08-10 |
Boehringer Ingelheim Pharma Kg |
Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases
|
|
US7247618B2
(en)
|
2001-04-30 |
2007-07-24 |
Tripathi Rajavashisth |
Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling
|
|
AU2002314495A1
(en)
|
2001-06-20 |
2003-01-02 |
Prochon Biotech Ltd. |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
DE60332483D1
(de)
|
2002-11-15 |
2010-06-17 |
Novartis Vaccines & Diagnostic |
Methoden zur verhinderung und behandlung von krebs-metastasierung und mit krebs-metastasierung einhergehendem knochenverlust
|
|
US7807389B2
(en)
|
2003-03-14 |
2010-10-05 |
University Of Rochester |
Methods and compositions related to joint inflammation diseases
|
|
NZ547279A
(en)
|
2003-10-22 |
2008-04-30 |
Keck Graduate Inst |
Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy
|
|
GB0325836D0
(en)
|
2003-11-05 |
2003-12-10 |
Celltech R&D Ltd |
Biological products
|
|
JP2007524671A
(ja)
|
2004-01-21 |
2007-08-30 |
カイロン コーポレイション |
Ｍ−ｃｓｆムテインおよびその使用
|
|
CA2565974A1
(en)
|
2004-05-14 |
2005-12-01 |
Receptor Biologix, Inc. |
Cell surface receptor isoforms and methods of identifying and using the same
|
|
EP1778842B8
(en)
|
2004-07-22 |
2012-03-21 |
Five Prime Therapeutics, Inc. |
Compositions and methods of use for mgd-csf in disease treatment
|
|
WO2006076288A2
(en)
|
2005-01-11 |
2006-07-20 |
Five Prime Therapeutics, Inc. |
Dna constructs for long-term expression of intravascularly injected naked dna
|
|
DE602006011574D1
(de)
|
2005-01-27 |
2010-02-25 |
Five Prime Therapeutics Inc |
Leitsequenzen zur anleitung von polypeptidsekretion und verfahren zur herstellung
|
|
US8003108B2
(en)
|
2005-05-03 |
2011-08-23 |
Amgen Inc. |
Sclerostin epitopes
|
|
AU2006320858A1
(en)
|
2005-11-10 |
2007-06-07 |
Receptor Biologix, Inc. |
Methods for production of receptor and ligand isoforms
|
|
WO2007075933A2
(en)
|
2005-12-21 |
2007-07-05 |
Cell Signaling Technology, Inc. |
Translocation and mutant csf1r kinase in human leukemia
|
|
EP1977238B1
(en)
|
2005-12-22 |
2016-09-28 |
Novartis AG |
Soluble human m-csf receptor and uses thereof
|
|
WO2007081879A2
(en)
|
2006-01-05 |
2007-07-19 |
Novartis Ag |
Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
|
|
PT2010528T
(pt)
|
2006-04-19 |
2017-12-21 |
Novartis Ag |
Compostos benzotiazole e benzoxazole 6-o-substituídos e métodos de inibição da sinalização csf-1r
|
|
US20100036091A1
(en)
|
2006-11-10 |
2010-02-11 |
Amgen Inc. |
Antibody-based diagnostics and therapeutics
|
|
WO2008060610A2
(en)
|
2006-11-17 |
2008-05-22 |
Biogen Idec Ma Inc. |
Systemic administration of colony stimulating factors to treat amyloid associated disorders
|
|
ATE494306T1
(de)
|
2007-02-14 |
2011-01-15 |
Vaccinex Inc |
Humanisierte anti-cd100-antikörper
|
|
WO2008124858A2
(en)
|
2007-04-11 |
2008-10-23 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges. M.B.H. |
Targeted receptor
|
|
AU2008254425A1
(en)
|
2007-05-21 |
2008-11-27 |
Novartis Ag |
CSF-1R inhibitors, compositions, and methods of use
|
|
WO2008150383A1
(en)
|
2007-05-30 |
2008-12-11 |
Albert Einstein College Of Medicine Of Yeshiva University |
Csf-1r mutants
|
|
SG10201500328QA
(en)
|
2007-08-21 |
2015-03-30 |
Amgen Inc |
Human c-fms antigen binding proteins
|
|
US7981415B2
(en)
|
2007-09-07 |
2011-07-19 |
Cisthera, Inc. |
Humanized PAI-1 antibodies
|
|
KR20100072075A
(ko)
|
2007-10-18 |
2010-06-29 |
노파르티스 아게 |
암 및 골 질환의 치료를 위한 ｃｓｆ-１ｒ 억제제
|
|
AU2008318656A1
(en)
|
2007-10-31 |
2009-05-07 |
Janssen Pharmaceutica N.V. |
Biomarker for assessing response to FMS treatment
|
|
EP2241333A1
(en)
|
2007-12-12 |
2010-10-20 |
National Cancer Center |
Therapeutic agent for mll leukemia and moz leukemia of which molecular target is m-csf receptor, and use thereof
|
|
US8470977B2
(en)
|
2008-03-14 |
2013-06-25 |
Transgene S.A. |
Antibody against the CSF-1R
|
|
RU2547586C2
(ru)
|
2008-03-14 |
2015-04-10 |
Трансжене С.А. |
Антитело против csf-1r
|
|
WO2009143018A2
(en)
|
2008-05-19 |
2009-11-26 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
CN102112478A
(zh)
|
2008-06-10 |
2011-06-29 |
普莱希科公司 |
用于激酶调节的5h-吡咯[2，3-b]吡嗪衍生物和其适应症
|
|
US8183207B2
(en)
|
2008-11-26 |
2012-05-22 |
Five Prime Therapeutics, Inc. |
Treatment of osteolytic disorders and cancer using CSF1R extracellular domain fusion molecules
|
|
US8080246B2
(en)
|
2008-11-26 |
2011-12-20 |
Five Prime Therapeutics, Inc. |
Colony stimulating factor 1 receptor (CSF1R) extracellular domain fusion molecules
|
|
WO2011057022A1
(en)
|
2009-11-06 |
2011-05-12 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
HUE026201T2
(en)
|
2009-12-10 |
2016-05-30 |
Hoffmann La Roche |
Antibodies binding to human CSF1R extracellular domain 4 and their use
|
|
UA108222C2
(xx)
|
2009-12-21 |
2015-04-10 |
|
СПОЛУКИ ЗАМІЩЕНОГО N-(1H-ІНДАЗОЛ-4-ІЛ)ІМІДАЗОЛ$1,2-а]ПІРИДИН-3-КАРБОКСАМІДУ ЯК ІНГІБІТОРИ cFMS
|
|
RU2617971C2
(ru)
|
2010-03-05 |
2017-04-28 |
Ф.Хоффманн-Ля Рош Аг |
Антитела против csf-1r человека и их применение
|
|
RU2617966C2
(ru)
*
|
2010-03-05 |
2017-04-28 |
Ф.Хоффманн-Ля Рош Аг |
Антитела против csf-1r человека и их применение
|
|
AR080698A1
(es)
|
2010-04-01 |
2012-05-02 |
Imclone Llc |
Anticuerpo o fragmento del mismo que especificamente enlaza la variante de csf -1r humano, composicion farmaceutica que lo comprende, su uso para la manufactura de un medicamento util para el tratamiento de cancer y metodo para determinar si un sujeto es candidato para tratamiento de cancer basado e
|
|
CA2797399C
(en)
|
2010-05-04 |
2021-03-02 |
Five Prime Therapeutics, Inc. |
Antibodies that bind csf1r
|
|
WO2012082573A1
(en)
|
2010-12-13 |
2012-06-21 |
Novartis Ag |
Predictive methods and methods of treating arthritis using il-17 antagonists
|
|
EP2768861A1
(en)
|
2011-10-21 |
2014-08-27 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
A m-dc8+ monocyte depleting agent for the prevention or the treatment of a condition associated with a chronic hyperactivation of the immune system
|
|
CA2851771C
(en)
|
2011-10-21 |
2018-09-11 |
Transgene Sa |
Modulation of macrophage activation
|
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
|
CN106267210A
(zh)
*
|
2012-03-26 |
2017-01-04 |
日本化学药品株式会社 |
骨·软组织中产生的巨细胞性肿瘤或软骨肉瘤的预防或治疗剂
|
|
CA2871445C
(en)
|
2012-05-11 |
2020-07-07 |
Five Prime Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
|
|
US20130302322A1
(en)
|
2012-05-11 |
2013-11-14 |
Five Prime Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
|
|
RU2718751C2
(ru)
|
2012-08-31 |
2020-04-14 |
Файв Прайм Терапьютикс, Инк. |
Способы лечения патологических состояний антителами, которые связываются с рецептором колониестимулирующего фактора 1 (csf1r)
|