TW201630937A - 用於治療ｐｖｎｓ之抗－ｃｓｆ１ｒ抗體 - Google Patents
用於治療ｐｖｎｓ之抗－ｃｓｆ１ｒ抗體 Download PDFInfo
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
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- Orthopedic Medicine & Surgery (AREA)
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| JP2020517256A (ja) | 2017-04-19 | 2020-06-18 | エルスター セラピューティクス， インコーポレイテッド | 多重特異性分子およびその使用 |
| JP7348899B2 (ja) | 2017-12-08 | 2023-09-21 | マレンゴ・セラピューティクス，インコーポレーテッド | 多重特異性分子及びその使用 |
| WO2019173361A2 (en) * | 2018-03-05 | 2019-09-12 | The Schepens Eye Research Institute, Inc. | A therapy for glaucoma and optic neuropathy by targeting colony stimulating factors |
| CN108948199B (zh) * | 2018-07-18 | 2019-06-21 | 博奥信生物技术（南京）有限公司 | 抗人csf-1r单克隆抗体及其用途 |
| CN109053887B (zh) * | 2018-07-18 | 2019-07-23 | 博奥信生物技术（南京）有限公司 | 一种抗人csf-1r单克隆抗体及用途 |
| US20210317461A1 (en) | 2018-08-09 | 2021-10-14 | Verseau Therapeutics, Inc. | Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof |
| EP3836951A1 (en) | 2018-08-13 | 2021-06-23 | Signablok, Inc. | Peptides and compositions for targeted treatment and imaging |
| JP7475335B2 (ja) * | 2018-09-13 | 2024-04-26 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | Ｃｓｆ－１ｒ抗体製剤 |
| AU2019346645A1 (en) | 2018-09-27 | 2021-04-29 | Marengo Therapeutics, Inc. | CSF1R/CCR2 multispecific antibodies |
| TW202112812A (zh) | 2019-05-24 | 2021-04-01 | 香港商安立璽榮生醫(香港)有限公司 | Csf1r抗體、il10融合蛋白及其用途 |
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| RU2617971C2 (ru) | 2010-03-05 | 2017-04-28 | Ф.Хоффманн-Ля Рош Аг | Антитела против csf-1r человека и их применение |
| RU2617966C2 (ru) * | 2010-03-05 | 2017-04-28 | Ф.Хоффманн-Ля Рош Аг | Антитела против csf-1r человека и их применение |
| AR080698A1 (es) | 2010-04-01 | 2012-05-02 | Imclone Llc | Anticuerpo o fragmento del mismo que especificamente enlaza la variante de csf -1r humano, composicion farmaceutica que lo comprende, su uso para la manufactura de un medicamento util para el tratamiento de cancer y metodo para determinar si un sujeto es candidato para tratamiento de cancer basado e |
| CA2797399C (en) | 2010-05-04 | 2021-03-02 | Five Prime Therapeutics, Inc. | Antibodies that bind csf1r |
| WO2012082573A1 (en) | 2010-12-13 | 2012-06-21 | Novartis Ag | Predictive methods and methods of treating arthritis using il-17 antagonists |
| EP2768861A1 (en) | 2011-10-21 | 2014-08-27 | Institut National de la Sante et de la Recherche Medicale (INSERM) | A m-dc8+ monocyte depleting agent for the prevention or the treatment of a condition associated with a chronic hyperactivation of the immune system |
| CA2851771C (en) | 2011-10-21 | 2018-09-11 | Transgene Sa | Modulation of macrophage activation |
| AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
| CN106267210A (zh) * | 2012-03-26 | 2017-01-04 | 日本化学药品株式会社 | 骨·软组织中产生的巨细胞性肿瘤或软骨肉瘤的预防或治疗剂 |
| CA2871445C (en) | 2012-05-11 | 2020-07-07 | Five Prime Therapeutics, Inc. | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
| US20130302322A1 (en) | 2012-05-11 | 2013-11-14 | Five Prime Therapeutics, Inc. | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
| RU2718751C2 (ru) | 2012-08-31 | 2020-04-14 | Файв Прайм Терапьютикс, Инк. | Способы лечения патологических состояний антителами, которые связываются с рецептором колониестимулирующего фактора 1 (csf1r) |
-
2015
- 2015-12-21 CA CA2969341A patent/CA2969341C/en active Active
- 2015-12-21 ES ES15823889T patent/ES2843586T3/es active Active
- 2015-12-21 US US14/976,346 patent/US10040858B2/en active Active
- 2015-12-21 EA EA201791421A patent/EA201791421A1/ru unknown
- 2015-12-21 BR BR112017013111A patent/BR112017013111A2/pt not_active Application Discontinuation
- 2015-12-21 WO PCT/US2015/067012 patent/WO2016106180A1/en not_active Ceased
- 2015-12-21 CN CN201580076553.8A patent/CN107257806B/zh active Active
- 2015-12-21 MX MX2017008218A patent/MX2017008218A/es unknown
- 2015-12-21 HK HK18105046.3A patent/HK1245804A1/zh unknown
- 2015-12-21 KR KR1020177020158A patent/KR20170096187A/ko not_active Withdrawn
- 2015-12-21 TW TW104143045A patent/TW201630937A/zh unknown
- 2015-12-21 EP EP15823889.9A patent/EP3237447B1/en active Active
- 2015-12-21 AU AU2015369854A patent/AU2015369854B2/en not_active Ceased
- 2015-12-21 JP JP2017533421A patent/JP6797801B2/ja active Active
- 2015-12-21 SG SG11201704792UA patent/SG11201704792UA/en unknown
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2017
- 2017-06-06 IL IL252716A patent/IL252716A0/en unknown
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2018
- 2018-06-22 US US16/015,371 patent/US10730949B2/en active Active
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2020
- 2020-06-25 US US16/911,806 patent/US20210009700A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018501254A (ja) | 2018-01-18 |
| ES2843586T3 (es) | 2021-07-19 |
| AU2015369854A1 (en) | 2017-06-15 |
| CA2969341C (en) | 2023-07-04 |
| BR112017013111A2 (pt) | 2018-05-15 |
| KR20170096187A (ko) | 2017-08-23 |
| CN107257806A (zh) | 2017-10-17 |
| IL252716A0 (en) | 2017-08-31 |
| US20190119390A1 (en) | 2019-04-25 |
| EA201791421A1 (ru) | 2017-10-31 |
| MX2017008218A (es) | 2017-10-18 |
| CN107257806B (zh) | 2021-08-10 |
| US20210009700A1 (en) | 2021-01-14 |
| AU2015369854B2 (en) | 2021-07-01 |
| WO2016106180A1 (en) | 2016-06-30 |
| US10730949B2 (en) | 2020-08-04 |
| CA2969341A1 (en) | 2016-06-30 |
| EP3237447A1 (en) | 2017-11-01 |
| EP3237447B1 (en) | 2020-12-02 |
| JP6797801B2 (ja) | 2020-12-09 |
| HK1245804A1 (zh) | 2018-08-31 |
| SG11201704792UA (en) | 2017-07-28 |
| US20160185869A1 (en) | 2016-06-30 |
| US10040858B2 (en) | 2018-08-07 |
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