JP2018501253A5 - - Google Patents

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Publication number

JP2018501253A5

JP2018501253A5 JP2017533396A JP2017533396A JP2018501253A5 JP 2018501253 A5 JP2018501253 A5 JP 2018501253A5 JP 2017533396 A JP2017533396 A JP 2017533396A JP 2017533396 A JP2017533396 A JP 2017533396A JP 2018501253 A5 JP2018501253 A5 JP 2018501253A5

Authority

JP

Japan

Prior art keywords

alkyl

hydrogen

group

haloalkyl

och

Prior art date

2015-12-21

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 229910052739 hydrogen Inorganic materials 0.000 claims 33
• 239000001257 hydrogen Substances 0.000 claims 33
• 150000001875 compounds Chemical class 0.000 claims 28
• 150000002431 hydrogen Chemical class 0.000 claims 21
• 125000001424 substituent group Chemical group 0.000 claims 19
• 125000004093 cyano group Chemical group *C#N 0.000 claims 13
• 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 12
• 125000000623 heterocyclic group Chemical group 0.000 claims 12
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 11
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 10
• 229910052736 halogen Inorganic materials 0.000 claims 10
• 150000002367 halogens Chemical class 0.000 claims 10
• 150000003839 salts Chemical class 0.000 claims 10
• 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 9
• 125000006650 (C2-C4) alkynyl group Chemical group 0.000 claims 7
• 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 6
• 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 6
• -1 methyl halide Chemical class 0.000 claims 6
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 6
• 150000001204 N-oxides Chemical class 0.000 claims 5
• 125000003545 alkoxy group Chemical group 0.000 claims 5
• 229910052799 carbon Inorganic materials 0.000 claims 5
• SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 5
• 125000004441 haloalkylsulfonyl group Chemical group 0.000 claims 4
• 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims 3
• 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims 3
• 125000006660 (C3-C4) halocycloalkyl group Chemical group 0.000 claims 3
• 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 3
• 241000607479 Yersinia pestis Species 0.000 claims 3
• 229910052731 fluorine Inorganic materials 0.000 claims 3
• 125000001188 haloalkyl group Chemical group 0.000 claims 3
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
• 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 claims 2
• 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 2
• 206010061217 Infestation Diseases 0.000 claims 2
• 125000000217 alkyl group Chemical group 0.000 claims 2
• 125000000304 alkynyl group Chemical group 0.000 claims 2
• 229910052801 chlorine Inorganic materials 0.000 claims 2
• 238000004132 cross linking Methods 0.000 claims 2
• 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 2
• 125000001153 fluoro group Chemical group F* 0.000 claims 2
• 125000005347 halocycloalkyl group Chemical group 0.000 claims 2
• 239000000463 material Substances 0.000 claims 2
• 229910052757 nitrogen Inorganic materials 0.000 claims 2
• 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 1
• 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 1
• 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
• PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
• 125000003118 aryl group Chemical group 0.000 claims 1
• 150000007981 azolines Chemical class 0.000 claims 1
• 229910052794 bromium Inorganic materials 0.000 claims 1
• 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
• 125000004432 carbon atom Chemical group C* 0.000 claims 1
• 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
• 239000011737 fluorine Substances 0.000 claims 1
• 125000004438 haloalkoxy group Chemical group 0.000 claims 1
• 125000004995 haloalkylthio group Chemical group 0.000 claims 1
• 125000000232 haloalkynyl group Chemical group 0.000 claims 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
• 208000015181 infectious disease Diseases 0.000 claims 1
• 239000007788 liquid Substances 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
• 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
• 229910052760 oxygen Inorganic materials 0.000 claims 1
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
• 229920006395 saturated elastomer Polymers 0.000 claims 1
• 239000007787 solid Substances 0.000 claims 1
• 229910052717 sulfur Inorganic materials 0.000 claims 1
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1