JP2018199733A5 - - Google Patents
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- Publication number
- JP2018199733A5 JP2018199733A5 JP2018182242A JP2018182242A JP2018199733A5 JP 2018199733 A5 JP2018199733 A5 JP 2018199733A5 JP 2018182242 A JP2018182242 A JP 2018182242A JP 2018182242 A JP2018182242 A JP 2018182242A JP 2018199733 A5 JP2018199733 A5 JP 2018199733A5
- Authority
- JP
- Japan
- Prior art keywords
- collagenase
- pharmaceutical composition
- composition according
- purified
- purified collagenase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000029816 Collagenase Human genes 0.000 claims 129
- 108060005980 Collagenase Proteins 0.000 claims 129
- 229960002424 collagenase Drugs 0.000 claims 129
- 239000008194 pharmaceutical composition Substances 0.000 claims 88
- 208000035484 Cellulite Diseases 0.000 claims 18
- 206010049752 Peau d'orange Diseases 0.000 claims 18
- 230000036232 cellulite Effects 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 18
- 238000002347 injection Methods 0.000 claims 12
- 239000007924 injection Substances 0.000 claims 12
- YRQNKMKHABXEJZ-UVQQGXFZSA-N chembl176323 Chemical compound C1C[C@]2(C)[C@@]3(C)CC(N=C4C[C@]5(C)CCC6[C@]7(C)CC[C@@H]([C@]7(CC[C@]6(C)[C@@]5(C)CC4=N4)C)CCCCCCCC)=C4C[C@]3(C)CCC2[C@]2(C)CC[C@H](CCCCCCCC)[C@]21C YRQNKMKHABXEJZ-UVQQGXFZSA-N 0.000 claims 11
- 241000193159 Hathewaya histolytica Species 0.000 claims 6
- 239000003246 corticosteroid Substances 0.000 claims 6
- 239000003937 drug carrier Substances 0.000 claims 6
- 238000001802 infusion Methods 0.000 claims 6
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims 6
- 229960005294 triamcinolone Drugs 0.000 claims 6
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77569006P | 2006-02-22 | 2006-02-22 | |
| US60/775,690 | 2006-02-22 | ||
| US11/703,269 US20070224184A1 (en) | 2006-02-22 | 2007-02-07 | Method for treating cellulite |
| US11/703,269 | 2007-02-07 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016179732A Division JP6498167B2 (ja) | 2006-02-22 | 2016-09-14 | セルライト処置用コラゲナーゼ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019200656A Division JP6853331B2 (ja) | 2006-02-22 | 2019-11-05 | セルライト処置用コラゲナーゼ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018199733A JP2018199733A (ja) | 2018-12-20 |
| JP2018199733A5 true JP2018199733A5 (cg-RX-API-DMAC7.html) | 2019-03-22 |
| JP6649449B2 JP6649449B2 (ja) | 2020-02-19 |
Family
ID=38325147
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008556445A Active JP5775658B2 (ja) | 2006-02-22 | 2007-02-22 | セルライト処置用コラゲナーゼ |
| JP2015095704A Pending JP2015134840A (ja) | 2006-02-22 | 2015-05-08 | セルライト処置用コラゲナーゼ |
| JP2016179732A Active JP6498167B2 (ja) | 2006-02-22 | 2016-09-14 | セルライト処置用コラゲナーゼ |
| JP2018182242A Active JP6649449B2 (ja) | 2006-02-22 | 2018-09-27 | セルライト処置用コラゲナーゼ |
| JP2019200656A Active JP6853331B2 (ja) | 2006-02-22 | 2019-11-05 | セルライト処置用コラゲナーゼ |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008556445A Active JP5775658B2 (ja) | 2006-02-22 | 2007-02-22 | セルライト処置用コラゲナーゼ |
| JP2015095704A Pending JP2015134840A (ja) | 2006-02-22 | 2015-05-08 | セルライト処置用コラゲナーゼ |
| JP2016179732A Active JP6498167B2 (ja) | 2006-02-22 | 2016-09-14 | セルライト処置用コラゲナーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019200656A Active JP6853331B2 (ja) | 2006-02-22 | 2019-11-05 | セルライト処置用コラゲナーゼ |
Country Status (19)
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6958150B2 (en) | 1994-12-15 | 2005-10-25 | Advance Biofactures Of Curacao, N.V. | Reduction of adipose tissue |
| SI1846022T1 (sl) * | 2005-01-21 | 2016-01-29 | The Research Foundation Of State University Of New York | Postopki za zdravljenje adhezivnega kapsulitisa |
| US20070224184A1 (en) * | 2006-02-22 | 2007-09-27 | The Research Foundation Of The State University Of New York | Method for treating cellulite |
| WO2008008468A2 (en) * | 2006-07-14 | 2008-01-17 | Duncan Diane I | Compositions and methods for fat reduction |
| US10071143B1 (en) | 2007-05-03 | 2018-09-11 | The Research Foundation For The State University Of New York | Methods for non-surgical treatment of carpal tunnel syndrome |
| TWI395593B (zh) | 2008-03-06 | 2013-05-11 | Halozyme Inc | 可活化的基質降解酵素之活體內暫時性控制 |
| CA2754461A1 (en) * | 2009-03-06 | 2010-09-10 | Halozyme, Inc. | Temperature sensitive mutants of matrix metalloprotease 1 and uses thereof |
| JP5284239B2 (ja) * | 2009-10-07 | 2013-09-11 | 株式会社メタコ | スクリーン装置 |
| FR2966734B1 (fr) * | 2010-10-29 | 2014-07-18 | Max Rombi | Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides |
| PT2768523T (pt) * | 2011-10-21 | 2019-08-29 | Endo Global Ventures | Processo para tratar ou reduzir a efp |
| PT2802652T (pt) | 2012-01-12 | 2019-09-10 | Endo Global Ventures | Enzimas de clostridium histolyticum |
| WO2014066622A2 (en) | 2012-10-24 | 2014-05-01 | The Research Foundation For The State University Of New York | Use of collagenase to treat glaucoma |
| US20150196625A9 (en) | 2013-01-07 | 2015-07-16 | Rudolph D. Paladini | Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof |
| US9744138B2 (en) | 2013-03-15 | 2017-08-29 | Biospecifics Technologies Corp. | Treatment method and product for uterine fibroids using purified collagenase |
| US10117892B2 (en) | 2013-08-29 | 2018-11-06 | Allergan, Inc. | Devices and methods for reducing the appearance of cellulite |
| CN103751102A (zh) | 2014-01-15 | 2014-04-30 | 上海交通大学 | 一种胶原酶温敏水凝胶及其制备方法和应用 |
| DK3589204T3 (da) * | 2017-03-01 | 2025-06-30 | Endo Operations Ltd | Apparat og fremgangsmåde til vurdering og behandling af cellulitis |
| AU2018244426B2 (en) | 2017-03-28 | 2024-09-19 | Endo Ventures Limited | Improved method of producing collagenase |
| WO2020021332A2 (en) * | 2018-07-12 | 2020-01-30 | Endo Global Aesthetics Limited | Injection techniques for the treatment of cellulite |
| WO2020021330A2 (en) * | 2018-07-12 | 2020-01-30 | Endo Global Aesthetics Limited | Injection techniques for the treatment of cellulite |
| WO2020058755A1 (en) * | 2018-09-18 | 2020-03-26 | Endo Global Aesthetics Limited | Compositions and methods for treating cellulite |
| KR20210113271A (ko) * | 2019-01-06 | 2021-09-15 | 엔도 글로벌 에스테틱스 리미티드 | 콜라게나제 제형 및 이의 제조 방법 |
| AU2020366008B2 (en) | 2019-10-15 | 2025-08-28 | Biospecifics Technologies Corp. | Treatment of uterine fibroids using purified collagenase |
| EP4041288A4 (en) * | 2019-11-26 | 2023-02-22 | Standard of Care Corporation | HYALURONIDASE COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING CELLULITE |
| CN119677498A (zh) * | 2022-05-10 | 2025-03-21 | 恩多全球美学有限公司 | 减少具有脂肪团的受试者中胶原酶介导的瘀伤的方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4338300A (en) * | 1981-02-05 | 1982-07-06 | The Regents Of The University Of California | Use of purified clostridial collangenase in the treatment of Peyronie's disease |
| US4524065A (en) * | 1983-08-04 | 1985-06-18 | Bio-Specifics N.V. | Method for the prevention and treatment of scars with enzymes |
| US4645668A (en) * | 1983-08-04 | 1987-02-24 | Biospecifics, Nv | Method for the prevention and treatment of scars with enzymes |
| US5393792A (en) * | 1991-11-20 | 1995-02-28 | Advance Biofactures Of Curacao, N.V. | High dosage topical forms of collagenase |
| US5332503A (en) * | 1993-04-16 | 1994-07-26 | Baxter International Inc. | Process for purifying collagenase |
| CA2189646C (en) * | 1994-06-24 | 1999-05-25 | Francis E. Dwulet | A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum |
| US5589171A (en) * | 1994-08-22 | 1996-12-31 | Advance Biofactures Of Curacao | Treatment of Dupuytren's disease with collagenase |
| CA2158822C (en) * | 1994-09-27 | 2008-12-23 | Kusuki Nishioka | Therapeutic agent for rheumatic disease |
| US6958150B2 (en) * | 1994-12-15 | 2005-10-25 | Advance Biofactures Of Curacao, N.V. | Reduction of adipose tissue |
| US5830741A (en) * | 1996-12-06 | 1998-11-03 | Boehringer Mannheim Corporation | Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease |
| US6086872A (en) * | 1997-03-27 | 2000-07-11 | Advance Biofactures Of Curacao, Nv | Amelioration of dupuytren's disease |
| CA2317066A1 (en) * | 1997-10-03 | 1999-04-15 | Lavipharm Laboratories, Inc. | A prolamine-plant polar lipid composition, its method of preparation and applications thereof |
| US6022539A (en) * | 1999-06-03 | 2000-02-08 | Advance Biofactures Of Curacao | Amelioration of peyronie's disease |
| WO2001013865A1 (en) * | 1999-08-20 | 2001-03-01 | Howard Murad | Pharmaceutical compositions and methods for reducing the appearance of cellulite |
| SI1846022T1 (sl) * | 2005-01-21 | 2016-01-29 | The Research Foundation Of State University Of New York | Postopki za zdravljenje adhezivnega kapsulitisa |
| US20070224184A1 (en) * | 2006-02-22 | 2007-09-27 | The Research Foundation Of The State University Of New York | Method for treating cellulite |
| US7811560B2 (en) * | 2006-01-30 | 2010-10-12 | Auxilium Us Holdings, Llc | Compositions and methods for treating collagen-mediated diseases |
| JO3400B1 (ar) * | 2010-09-30 | 2019-10-20 | Ferring Bv | مركب صيدلاني من كاربيتوسين |
| US20210169844A1 (en) * | 2019-12-10 | 2021-06-10 | Tulex Pharmaceuticals Inc. | Compositions and methods for treating epilepsy, seizures and other conditions |
-
2007
- 2007-02-07 US US11/703,269 patent/US20070224184A1/en not_active Abandoned
- 2007-02-22 JP JP2008556445A patent/JP5775658B2/ja active Active
- 2007-02-22 BR BRPI0708186-3A patent/BRPI0708186A2/pt not_active Application Discontinuation
- 2007-02-22 MX MX2008010767A patent/MX2008010767A/es active IP Right Grant
- 2007-02-22 CA CA2643171A patent/CA2643171C/en active Active
- 2007-02-22 WO PCT/US2007/004752 patent/WO2007100675A2/en not_active Ceased
- 2007-02-22 DK DK07751508.8T patent/DK1991258T3/en active
- 2007-02-22 HU HUE07751508A patent/HUE025918T2/en unknown
- 2007-02-22 NZ NZ570642A patent/NZ570642A/en unknown
- 2007-02-22 PL PL07751508T patent/PL1991258T3/pl unknown
- 2007-02-22 KR KR1020117028099A patent/KR20120006063A/ko not_active Ceased
- 2007-02-22 RS RS20150714A patent/RS54372B1/sr unknown
- 2007-02-22 PT PT77515088T patent/PT1991258E/pt unknown
- 2007-02-22 SI SI200731702T patent/SI1991258T1/sl unknown
- 2007-02-22 HR HRP20151182TT patent/HRP20151182T1/hr unknown
- 2007-02-22 EP EP07751508.8A patent/EP1991258B1/en active Active
- 2007-02-22 ES ES07751508.8T patent/ES2553184T3/es active Active
- 2007-02-22 AU AU2007221225A patent/AU2007221225B2/en active Active
- 2007-02-22 KR KR1020087022877A patent/KR20080108996A/ko not_active Ceased
-
2008
- 2008-08-21 IL IL193639A patent/IL193639A/en active IP Right Grant
-
2015
- 2015-05-08 JP JP2015095704A patent/JP2015134840A/ja active Pending
-
2016
- 2016-06-03 US US15/173,092 patent/US10123959B2/en active Active
- 2016-09-14 JP JP2016179732A patent/JP6498167B2/ja active Active
-
2018
- 2018-09-27 JP JP2018182242A patent/JP6649449B2/ja active Active
- 2018-10-19 US US16/165,910 patent/US20190053995A1/en not_active Abandoned
-
2019
- 2019-11-05 JP JP2019200656A patent/JP6853331B2/ja active Active
-
2022
- 2022-04-22 US US17/727,118 patent/US20220249348A1/en active Pending
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