JP2018196379A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018196379A5 JP2018196379A5 JP2018121829A JP2018121829A JP2018196379A5 JP 2018196379 A5 JP2018196379 A5 JP 2018196379A5 JP 2018121829 A JP2018121829 A JP 2018121829A JP 2018121829 A JP2018121829 A JP 2018121829A JP 2018196379 A5 JP2018196379 A5 JP 2018196379A5
- Authority
- JP
- Japan
- Prior art keywords
- mutation
- primer
- amplification
- amplification reaction
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261652827P | 2012-05-29 | 2012-05-29 | |
| US61/652,827 | 2012-05-29 | ||
| US13/840,142 | 2013-03-15 | ||
| US13/840,142 US10077474B2 (en) | 2012-05-29 | 2013-03-15 | Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515106A Division JP6448534B2 (ja) | 2012-05-29 | 2013-05-28 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018196379A JP2018196379A (ja) | 2018-12-13 |
| JP2018196379A5 true JP2018196379A5 (https=) | 2019-02-14 |
Family
ID=49670689
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515106A Expired - Fee Related JP6448534B2 (ja) | 2012-05-29 | 2013-05-28 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
| JP2018121829A Pending JP2018196379A (ja) | 2012-05-29 | 2018-06-27 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515106A Expired - Fee Related JP6448534B2 (ja) | 2012-05-29 | 2013-05-28 | ヒトbrafのコドン600における一塩基多型(snp)を検出する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10077474B2 (https=) |
| EP (2) | EP3604552A1 (https=) |
| JP (2) | JP6448534B2 (https=) |
| AU (2) | AU2013267660B2 (https=) |
| CA (1) | CA2875281A1 (https=) |
| ES (1) | ES2751371T3 (https=) |
| WO (1) | WO2013181125A2 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| RU2671980C2 (ru) | 2011-02-09 | 2018-11-08 | Натера, Инк. | Способы неинвазивного пренатального установления плоидности |
| EP3741871A3 (en) | 2012-04-19 | 2021-02-17 | The Medical College of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free dna |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| CN104928355A (zh) * | 2014-03-19 | 2015-09-23 | 李跃 | 检测braf基因突变的方法及其试剂盒 |
| CA2945962C (en) | 2014-04-21 | 2023-08-29 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| EP3307911B1 (en) | 2015-06-11 | 2020-12-09 | Bio-Rad Laboratories, Inc. | Amplification assay with a probe competitor |
| CN108699553B (zh) | 2015-12-31 | 2023-08-04 | 奎斯特诊断投资有限责任公司 | 用于筛选甲状腺癌中突变的组合物和方法 |
| RU2760913C2 (ru) | 2016-04-15 | 2021-12-01 | Натера, Инк. | Способы выявления рака легкого |
| WO2017190104A1 (en) * | 2016-04-29 | 2017-11-02 | Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cancer |
| CN105861689A (zh) * | 2016-05-06 | 2016-08-17 | 北京晋祺生物科技有限公司 | 一种cyp3a5*3的检测引物组合物、试剂盒及方法 |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US11773434B2 (en) | 2017-06-20 | 2023-10-03 | The Medical College Of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free DNA |
| WO2018237088A1 (en) | 2017-06-20 | 2018-12-27 | Bio-Rad Laboratories, Inc. | DIGITAL AMPLIFICATION ASSAYS FOR GENETIC INSTABILITY |
| WO2019099420A1 (en) * | 2017-11-15 | 2019-05-23 | Yan Wang | A method for detecting multiple dna mutations and copy number variations |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| US12024738B2 (en) | 2018-04-14 | 2024-07-02 | Natera, Inc. | Methods for cancer detection and monitoring |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| EP3906314A4 (en) * | 2018-12-31 | 2022-11-23 | Abbott Molecular Inc. | IMPROVED AMPLIFICATION OF NUCLEIC ACIDS |
| KR102321902B1 (ko) * | 2019-01-11 | 2021-11-05 | 주식회사 진캐스트 | Braf 돌연변이 검출을 위한 dna 중합효소 및 이를 포함하는 키트 |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| IL291819A (en) * | 2019-10-02 | 2022-06-01 | Univ Rutgers | Assay methods and kits for detecting rare sequence variants |
| AU2021264510A1 (en) * | 2020-04-28 | 2022-12-01 | Cepheid | Pseudo-complementary bases in genotyping and nucleic acid sequencing |
| WO2023013421A1 (ja) * | 2021-08-03 | 2023-02-09 | 国立大学法人群馬大学 | 腫瘍マーカーca19-9によるがん診断の精度向上を目的とする血液型関連糖鎖遺伝子の迅速スクリーニングのための新規手法 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| CA1202962A (en) | 1982-10-19 | 1986-04-08 | David P. Clifford | Substituted n-phenyl-n'-benzoyl ureas and their use as insecticides and acaricides |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5310893A (en) | 1986-03-31 | 1994-05-10 | Hoffmann-La Roche Inc. | Method for HLA DP typing |
| CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| US5604099A (en) | 1986-03-13 | 1997-02-18 | Hoffmann-La Roche Inc. | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| US4851331A (en) | 1986-05-16 | 1989-07-25 | Allied Corporation | Method and kit for polynucleotide assay including primer-dependant DNA polymerase |
| US5561058A (en) | 1986-08-22 | 1996-10-01 | Hoffmann-La Roche Inc. | Methods for coupled high temperatures reverse transcription and polymerase chain reactions |
| US5310652A (en) | 1986-08-22 | 1994-05-10 | Hoffman-La Roche Inc. | Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription |
| US5693517A (en) | 1987-06-17 | 1997-12-02 | Roche Molecular Systems, Inc. | Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions |
| US5322770A (en) | 1989-12-22 | 1994-06-21 | Hoffman-Laroche Inc. | Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription |
| IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
| US5639611A (en) | 1988-12-12 | 1997-06-17 | City Of Hope | Allele specific polymerase chain reaction |
| US5137806A (en) | 1989-12-11 | 1992-08-11 | Board Of Regents, The University Of Texas System | Methods and compositions for the detection of sequences in selected DNA molecules |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| DE69128520T2 (de) | 1990-10-31 | 1998-07-09 | Tosoh Corp | Verfahren zum Nachweis oder Quantifizierung von Zielnukleinsäuren |
| US5994056A (en) | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| DK51092D0 (da) | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| CA2081582A1 (en) | 1991-11-05 | 1993-05-06 | Teodorica Bugawan | Methods and reagents for hla class i dna typing |
| ATE198358T1 (de) | 1992-04-27 | 2001-01-15 | Dartmouth College | Detektion von gensequenzen in biologischen flüssigkeiten |
| CA2126952C (en) | 1994-06-28 | 2010-12-14 | Sithian Pandian | Probe, kit, and method of amplification for increasing the sensitivity of nucleic acid hybridization assays |
| US6235480B1 (en) | 1998-03-13 | 2001-05-22 | Promega Corporation | Detection of nucleic acid hybrids |
| US20030211483A1 (en) | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
| US7378232B2 (en) | 2002-05-09 | 2008-05-27 | New York University | Assay for melanogenesis |
| US20050277118A1 (en) | 2002-09-11 | 2005-12-15 | Roth Richard B | Methods for identifying subjects at risk of melanoma and treatments thereof |
| JP2006500057A (ja) | 2002-09-26 | 2006-01-05 | ノバルティス アクチエンゲゼルシャフト | B−raf遺伝子における突然変異のpcrに基づく診断的検出方法 |
| US20040121374A1 (en) | 2002-10-02 | 2004-06-24 | Yoshihide Iwaki | Method for detecting single nucleotide polymorphisms |
| JP4116856B2 (ja) | 2002-10-02 | 2008-07-09 | 富士フイルム株式会社 | 1塩基多型の検出方法 |
| US7250289B2 (en) * | 2002-11-20 | 2007-07-31 | Affymetrix, Inc. | Methods of genetic analysis of mouse |
| US7378233B2 (en) | 2003-04-12 | 2008-05-27 | The Johns Hopkins University | BRAF mutation T1796A in thyroid cancers |
| ES2385485T3 (es) | 2003-12-03 | 2012-07-25 | Abbott Laboratories | Sonda de ácido nucleico lineal de doble hebra y usos de la misma |
| EP1541695A1 (en) | 2003-12-09 | 2005-06-15 | Nanogen Recognomics GmbH | Use of a mutation in the BRAF gene for the determination of the malignancy of melanoma cells |
| WO2005066346A1 (ja) | 2003-12-26 | 2005-07-21 | Takeshi Nagasaka | 核酸増幅用プライマー、核酸増幅用プライマーセット及びこれを用いた癌の検査方法 |
| ES2244308B1 (es) | 2004-01-21 | 2007-02-16 | Oryzon Genomics, S.A. | Metodo de diagnostico molecular y tratamiento en cancer colorrectal esporadico inestable. |
| US7442507B2 (en) | 2005-01-24 | 2008-10-28 | New York University School Of Medicine | Methods for detecting circulating mutant BRAF DNA |
| US20070020657A1 (en) | 2005-05-20 | 2007-01-25 | Grebe Stefan K | Methods for detecting circulating tumor cells |
| UA95244C2 (ru) * | 2005-06-22 | 2011-07-25 | Плексикон, Инк. | Соединения и способ модулирования активности киназ, и показания для их применения |
| WO2007009013A2 (en) | 2005-07-13 | 2007-01-18 | University Of Utah Research Foundation | Methods and compositions related to a braf mutation and microsatellite stability |
| WO2007106534A2 (en) | 2006-03-14 | 2007-09-20 | Harbor-Ucla Research And Education Institute | Selective amplification of minority mutations using primer blocking high-affinity oligonucleotides |
| US7803543B2 (en) * | 2007-01-19 | 2010-09-28 | Chang Gung University | Methods and kits for the detection of nucleotide mutations using peptide nucleic acid as both PCR clamp and sensor probe |
| EP2129791A4 (en) | 2007-02-26 | 2010-07-28 | Wayne John Cancer Inst | BENEFITS OF THE B-RAF DNA MUTATION FOR THE DIAGNOSIS AND TREATMENT OF CANCER |
| US20110212991A1 (en) | 2007-09-11 | 2011-09-01 | Roche Molecular Systems, Inc. | Diagnostic Test for Susceptibility to B-RAF Kinase Inhibitors |
| US20100173294A1 (en) | 2007-09-11 | 2010-07-08 | Roche Molecular Systems, Inc. | Diagnostic test for susceptibility to b-raf kinase inhibitors |
| MX2010005960A (es) | 2007-11-30 | 2010-06-11 | Schering Corp | Biomarcadores de braf. |
| WO2010011884A2 (en) | 2008-07-25 | 2010-01-28 | University Of Florida Research Foundation, Inc. | Novel nucleic acid-based molecular probes |
| WO2010028288A2 (en) | 2008-09-05 | 2010-03-11 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
| CN101487051B (zh) | 2009-02-24 | 2011-07-20 | 广州益善生物技术有限公司 | Braf基因突变的检测探针、液相芯片及其检测方法 |
| EP2464751B1 (en) | 2009-08-11 | 2017-05-24 | Response Genetics, Inc. | Methods, primers, probes and kits useful for the detection of braf mutations |
| US8728763B2 (en) * | 2009-08-11 | 2014-05-20 | Response Genetics | Methods, primers, probes and kits useful for the detection of BRAF mutations |
| KR101825117B1 (ko) | 2010-02-01 | 2018-02-06 | 주식회사 파나진 | Pna 기반의 실시간 pcr 클램핑을 이용한 braf 돌연변이 검출 방법 및 키트 |
| CN102161990A (zh) * | 2010-02-24 | 2011-08-24 | 北京雅康博生物科技有限公司 | 用于定量检测braf突变的试剂盒 |
| ES2576061T3 (es) | 2010-02-25 | 2016-07-05 | Dana-Farber Cancer Institute, Inc. | Mutaciones de BRAF que confieren resistencia a inhibidores de BRAF |
| WO2011104694A2 (en) | 2010-02-26 | 2011-09-01 | GAMMAGENETICS Sàrl | Detection of braf v600e mutation by allele specific real time quantitative pcr (as-qpcr) using locked nucleic acids primers and beacon probes |
| EP2553463B1 (en) | 2010-03-26 | 2017-05-03 | Hongzhi Zou | Methods and materials for detecting colorectal neoplasm |
| CN102234684B (zh) | 2010-04-23 | 2014-01-01 | 益善生物技术股份有限公司 | Braf基因突变检测特异性引物和液相芯片 |
| EP2426217A1 (en) | 2010-09-03 | 2012-03-07 | Centre National de la Recherche Scientifique (CNRS) | Analytical methods for cell free nucleic acids and applications |
-
2013
- 2013-03-15 US US13/840,142 patent/US10077474B2/en not_active Expired - Fee Related
- 2013-05-28 EP EP19187147.4A patent/EP3604552A1/en not_active Withdrawn
- 2013-05-28 JP JP2015515106A patent/JP6448534B2/ja not_active Expired - Fee Related
- 2013-05-28 CA CA2875281A patent/CA2875281A1/en not_active Abandoned
- 2013-05-28 AU AU2013267660A patent/AU2013267660B2/en not_active Ceased
- 2013-05-28 WO PCT/US2013/042817 patent/WO2013181125A2/en not_active Ceased
- 2013-05-28 EP EP13798093.4A patent/EP2855708B1/en active Active
- 2013-05-28 ES ES13798093T patent/ES2751371T3/es active Active
-
2018
- 2018-06-27 JP JP2018121829A patent/JP2018196379A/ja active Pending
- 2018-08-20 US US16/105,057 patent/US20190032133A1/en not_active Abandoned
- 2018-10-19 AU AU2018250508A patent/AU2018250508A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018196379A5 (https=) | ||
| CN106661627B (zh) | 使用重叠非等位基因特异性引物和等位基因特异性阻断剂寡核苷酸的组合物进行等位基因特异性扩增 | |
| JP2005270108A5 (https=) | ||
| JP2021510541A5 (https=) | ||
| CN111699269A (zh) | 新引物及其用途 | |
| JP2015156872A5 (https=) | ||
| JP2017510244A5 (https=) | ||
| JP2017537658A5 (https=) | ||
| JP2014083053A5 (https=) | ||
| JP7343264B2 (ja) | Dnaライブラリーの作製方法及びdnaライブラリーを用いたゲノムdna解析方法 | |
| JP2012513216A5 (https=) | ||
| CN105378111A (zh) | 进行聚合酶链式反应的方法及其相关应用 | |
| Summerer et al. | Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing | |
| JP2010035532A (ja) | アレル特異的pcr法 | |
| JP2023535407A5 (https=) | ||
| JP2016527904A5 (https=) | ||
| JP2017532030A5 (https=) | ||
| JP2008504825A5 (https=) | ||
| ES2843848T3 (es) | Ensayo de referencia para múltiples copias | |
| KR101856205B1 (ko) | 핵산의 대립형질 특이적 프라이머 및 이를 이용한 유전형 판별 방법 | |
| JP2005323565A (ja) | 標的dna配列において一塩基変異多型の存在を検出する方法及びキット | |
| US20230407383A1 (en) | Gene specific spatial rolling circle amplification and ngs sequencing | |
| CN111808977A (zh) | 一种由snp所引起利福平类抗生素耐药的抗性基因的特异性引物的设计方法及检测方法 | |
| WO2009079733A1 (en) | Determination of variants produced upon replication or transcription of nucleic acid sequences | |
| CN104152542B (zh) | 肿瘤abl1基因位点分型检测试剂盒、使用方法及应用 |