JP2018117645A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018117645A5 JP2018117645A5 JP2018091537A JP2018091537A JP2018117645A5 JP 2018117645 A5 JP2018117645 A5 JP 2018117645A5 JP 2018091537 A JP2018091537 A JP 2018091537A JP 2018091537 A JP2018091537 A JP 2018091537A JP 2018117645 A5 JP2018117645 A5 JP 2018117645A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- seq
- subject
- nucleic acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 201000008827 tuberculosis Diseases 0.000 claims 9
- 239000008280 blood Substances 0.000 claims 8
- 210000004369 blood Anatomy 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004414 DNA Proteins 0.000 claims 5
- 102000053602 DNA Human genes 0.000 claims 5
- 241000187479 Mycobacterium tuberculosis Species 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 108010067770 Endopeptidase K Proteins 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 210000002421 cell wall Anatomy 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161470774P | 2011-04-01 | 2011-04-01 | |
| US61/470,774 | 2011-04-01 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014502902A Division JP6430826B2 (ja) | 2011-04-01 | 2012-04-02 | 無細胞病原体特異的核酸を検出する方法およびキット |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018117645A JP2018117645A (ja) | 2018-08-02 |
| JP2018117645A5 true JP2018117645A5 (enExample) | 2018-09-13 |
Family
ID=46932429
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014502902A Expired - Fee Related JP6430826B2 (ja) | 2011-04-01 | 2012-04-02 | 無細胞病原体特異的核酸を検出する方法およびキット |
| JP2018091537A Pending JP2018117645A (ja) | 2011-04-01 | 2018-05-10 | 無細胞病原体特異的核酸を検出する方法およびキット |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014502902A Expired - Fee Related JP6430826B2 (ja) | 2011-04-01 | 2012-04-02 | 無細胞病原体特異的核酸を検出する方法およびキット |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20140147851A1 (enExample) |
| EP (1) | EP2694680A4 (enExample) |
| JP (2) | JP6430826B2 (enExample) |
| CN (2) | CN109280713A (enExample) |
| AU (3) | AU2012236109A1 (enExample) |
| RU (1) | RU2644672C2 (enExample) |
| WO (1) | WO2012135815A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140147851A1 (en) * | 2011-04-01 | 2014-05-29 | Occam Biolabs, Inc. | Methods and kits for detecting cell-free pathogen-specific nucleic acids |
| EP2761662B1 (en) * | 2011-09-30 | 2022-02-02 | Sony Group Corporation | Tungsten gates for non-planar transistors |
| EP3003561B1 (en) | 2013-05-24 | 2018-12-19 | Occam Biolabs, Inc. | System and method for collecting a sample of nucleic acid |
| US9644232B2 (en) | 2013-07-26 | 2017-05-09 | General Electric Company | Method and device for collection and amplification of circulating nucleic acids |
| CN105829589B (zh) | 2013-11-07 | 2021-02-02 | 小利兰·斯坦福大学理事会 | 用于分析人体微生物组及其组分的无细胞核酸 |
| CN104894226A (zh) * | 2014-03-07 | 2015-09-09 | 复旦大学 | 检测实验室结核分枝杆菌微环境表面污染的方法及其检测试剂盒 |
| CN111841677A (zh) | 2014-11-21 | 2020-10-30 | 澳康姆生物实验室公司 | 用于收集核酸样本的系统和方法 |
| US11111520B2 (en) | 2015-05-18 | 2021-09-07 | Karius, Inc. | Compositions and methods for enriching populations of nucleic acids |
| CN115161178A (zh) | 2015-09-09 | 2022-10-11 | 集联健康有限公司 | 用于样品收集、稳定化和保存的系统、方法和装置 |
| EP3141612A1 (en) | 2015-09-10 | 2017-03-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Method and device for nucleic acid based diagnostic approaches including the determination of a deviant condtion, especially a health condition and/or pathogenic condition of a sample |
| WO2017077999A1 (ja) * | 2015-11-06 | 2017-05-11 | 公立大学法人横浜市立大学 | 結核菌群由来ｄｎａの検出方法 |
| CN105296661A (zh) * | 2015-12-02 | 2016-02-03 | 北京市结核病胸部肿瘤研究所 | 通过检测游离核酸诊断结核病的试剂盒及其应用 |
| EP3978627A1 (en) | 2016-03-25 | 2022-04-06 | Karius, Inc. | Methods using synthetic nucleic acid spike-ins |
| WO2018008083A1 (ja) * | 2016-07-05 | 2018-01-11 | 株式会社日立製作所 | Ｄｎａ検出方法およびそのための装置 |
| EP3559231B1 (en) | 2016-11-11 | 2022-08-17 | Bio-Rad Laboratories, Inc. | Methods for processing nucleic acid samples |
| AU2018211530B2 (en) * | 2017-01-30 | 2022-09-15 | Safeguard Biosystems Holdings Ltd. | Bead beating tube and method for extracting deoxyribonucleic acid and/or ribonucleic acid from microorganisms |
| EP3610034B1 (en) | 2017-04-12 | 2022-06-08 | Karius, Inc. | Sample preparation methods, systems and compositions |
| CN108165560B (zh) * | 2017-12-01 | 2021-06-08 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CN108165563B (zh) * | 2017-12-01 | 2021-02-19 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CN108165561B (zh) * | 2017-12-01 | 2021-06-18 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CN108165562B (zh) * | 2017-12-01 | 2021-06-08 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| WO2019178157A1 (en) | 2018-03-16 | 2019-09-19 | Karius, Inc. | Sample series to differentiate target nucleic acids from contaminant nucleic acids |
| WO2020106893A1 (en) | 2018-11-21 | 2020-05-28 | Karius, Inc. | Direct-to-library methods, systems, and compositions |
| CN111876411A (zh) * | 2019-09-06 | 2020-11-03 | 深圳微伴生物有限公司 | 获得cfDNA标准品的引物组、PCR扩增阳性标准品及其制备方法、试剂盒及应用 |
| KR102286570B1 (ko) * | 2019-11-19 | 2021-08-05 | 대한민국 | 소변 시료를 이용하여 결핵 진단용 프라이머, 프로브, 키트 및 이들의 용도 |
| CN114480691A (zh) * | 2022-01-24 | 2022-05-13 | 广州迪澳基因科技有限公司 | 基于熔解曲线检测结核分枝杆菌复合菌群的方法及试剂盒 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE186749T1 (de) * | 1991-08-15 | 1999-12-15 | Hoffmann La Roche | Primerpaar zum nachweis von mycobacterium |
| US6458366B1 (en) * | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| DK0975807T3 (da) * | 1997-05-02 | 2007-01-29 | Gen Probe Inc | To-trins hybridisering og indfangning af et polynukleotid |
| DE19752898A1 (de) * | 1997-11-28 | 1999-08-05 | Centeon Pharma Gmbh | Verfahren zum Nachweis hoher Vierenkonzentrationen im Blutplasma und/oder Blutserum mittels der Polymerasekettenreaktion |
| US6951722B2 (en) * | 1999-03-19 | 2005-10-04 | Takara Bio Inc. | Method for amplifying nucleic acid sequence |
| TWI237695B (en) * | 1999-12-14 | 2005-08-11 | Joy Biomedical Corp | Helicobacter pylori antigens in blood |
| EP1315814A2 (en) * | 2000-07-24 | 2003-06-04 | Inpharmatica Limited | Adhesion molecules |
| CN1388378A (zh) * | 2002-06-17 | 2003-01-01 | 四川大学 | 结核分枝杆菌诊断检测试剂 |
| WO2005075683A1 (en) * | 2004-02-03 | 2005-08-18 | Postech Foundation | High throughput device for performing continuous-flow reactions |
| EP2351857B1 (en) * | 2005-02-17 | 2014-10-29 | TrovaGene, Inc. | Compositions and methods for detecting pathogen specific nucleic acids in urine |
| US7993881B2 (en) * | 2005-11-15 | 2011-08-09 | Genoid Kft | Method for detecting pathogens using molecular beacons |
| US8741565B2 (en) * | 2005-12-30 | 2014-06-03 | Honeywell International Inc. | Oligonucleotide microarray for identification of pathogens |
| US20090142757A1 (en) * | 2007-11-30 | 2009-06-04 | Asiagen Corporation | Strip and method for detecting nucleotide amplification products of mycobacterium tuberculosis and non-tuberculous mycobacterium |
| US8029806B2 (en) * | 2008-04-16 | 2011-10-04 | Asiagen Corporation | Method for diagnosing of Mycobacterium tuberculosis |
| WO2010080691A1 (en) * | 2009-01-06 | 2010-07-15 | Qimin You | Cross priming amplification of target nucleic acids |
| US20140147851A1 (en) * | 2011-04-01 | 2014-05-29 | Occam Biolabs, Inc. | Methods and kits for detecting cell-free pathogen-specific nucleic acids |
-
2012
- 2012-04-02 US US14/009,199 patent/US20140147851A1/en not_active Abandoned
- 2012-04-02 RU RU2013148806A patent/RU2644672C2/ru not_active IP Right Cessation
- 2012-04-02 AU AU2012236109A patent/AU2012236109A1/en not_active Abandoned
- 2012-04-02 EP EP12765867.2A patent/EP2694680A4/en not_active Withdrawn
- 2012-04-02 WO PCT/US2012/031814 patent/WO2012135815A2/en not_active Ceased
- 2012-04-02 CN CN201811203829.6A patent/CN109280713A/zh active Pending
- 2012-04-02 CN CN201280026842.3A patent/CN103814139B/zh not_active Expired - Fee Related
- 2012-04-02 JP JP2014502902A patent/JP6430826B2/ja not_active Expired - Fee Related
-
2017
- 2017-05-09 AU AU2017203071A patent/AU2017203071A1/en not_active Abandoned
- 2017-07-31 US US15/664,074 patent/US20170369932A1/en not_active Abandoned
-
2018
- 2018-05-10 JP JP2018091537A patent/JP2018117645A/ja active Pending
-
2019
- 2019-07-05 AU AU2019204844A patent/AU2019204844A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018117645A5 (enExample) | ||
| Jiang et al. | Robust strand exchange reactions for the sequence-specific, real-time detection of nucleic acid amplicons | |
| JP6666268B2 (ja) | 液滴ソートによるヌクレオチド配列排除富化（ｎｅｅｄｌｓ） | |
| JP2024102334A (ja) | 連続的な増幅反応のための方法および装置 | |
| Shi et al. | Triggered isothermal PCR by denaturation bubble-mediated strand exchange amplification | |
| CN112020562A (zh) | 基于crispr效应系统的诊断 | |
| JP2015156872A5 (enExample) | ||
| KR20140044323A (ko) | 핵산의 왕복 증폭 반응 | |
| JP2016073273A5 (enExample) | ||
| DK201000356A (en) | New nucleotide sequence amplification Method | |
| JP2017521086A5 (enExample) | ||
| US20250101500A1 (en) | Amplification assays using crispr-cas based detection | |
| JP2010035552A5 (enExample) | ||
| Oreskovic et al. | Ultrasensitive hybridization capture: reliable detection of< 1 copy/mL short cell-free DNA from large-volume urine samples | |
| JP2016019495A (ja) | 核酸増幅法 | |
| JP5200302B2 (ja) | ヘリカーゼを使用するｒｎａターゲットの同定 | |
| WO2017096492A1 (en) | Nucleic acid catenane with a linking duplex biosensor for detection of a microorganism target | |
| JP2014083052A5 (enExample) | ||
| US20160153029A1 (en) | Dna sequences to assess contamination in dna sequencing | |
| Wang et al. | Nested phosphorothioated hybrid primer-mediated isothermal amplification for specific and dye-based subattomolar nucleic acid detection at low temperatures | |
| JP2017143810A5 (enExample) | ||
| JPWO2021046278A5 (enExample) | ||
| JP2011502487A5 (enExample) | ||
| CN108624587A (zh) | 高效快速获取植物rna病毒末端序列的race方法 | |
| JP2018153157A (ja) | Ｒｎａ増幅方法、ｒｎａ検出方法及びアッセイキット |