JP2018033559A5 - - Google Patents

Info

Publication number

JP2018033559A5

JP2018033559A5 JP2016167488A JP2016167488A JP2018033559A5 JP 2018033559 A5 JP2018033559 A5 JP 2018033559A5 JP 2016167488 A JP2016167488 A JP 2016167488A JP 2016167488 A JP2016167488 A JP 2016167488A JP 2018033559 A5 JP2018033559 A5 JP 2018033559A5

Authority

JP

Japan

Prior art keywords

acid

water

producing

raw material

insoluble

Prior art date

2016-08-30

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
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• 238000004519 manufacturing process Methods 0.000 claims description 19
• 239000002994 raw material Substances 0.000 claims description 15
• KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
• 239000002253 acid Substances 0.000 claims description 10
• 229920001282 polysaccharide Polymers 0.000 claims description 8
• 239000005017 polysaccharide Substances 0.000 claims description 8
• 150000004804 polysaccharides Chemical class 0.000 claims description 8
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
• WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 claims description 6
• OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
• MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 6
• 150000008065 acid anhydrides Chemical class 0.000 claims description 6
• 150000003839 salts Chemical class 0.000 claims description 6
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 4
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
• OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims description 4
• 150000001261 hydroxy acids Chemical class 0.000 claims description 4
• 239000007788 liquid Substances 0.000 claims description 3
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 2
• RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 claims description 2
• 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 2
• KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 2
• 239000000783 alginic acid Substances 0.000 claims description 2
• 235000010443 alginic acid Nutrition 0.000 claims description 2
• 229920000615 alginic acid Polymers 0.000 claims description 2
• 229960001126 alginic acid Drugs 0.000 claims description 2
• 150000004781 alginic acids Chemical class 0.000 claims description 2
• JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 claims description 2
• KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 2
• 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
• 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 2
• 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 2
• 229940105329 carboxymethylcellulose Drugs 0.000 claims description 2
• 235000011187 glycerol Nutrition 0.000 claims description 2
• 229920002674 hyaluronan Polymers 0.000 claims description 2
• 229960003160 hyaluronic acid Drugs 0.000 claims description 2
• 235000006408 oxalic acid Nutrition 0.000 claims description 2
• WYVAMUWZEOHJOQ-UHFFFAOYSA-N propionic anhydride Chemical compound CCC(=O)OC(=O)CC WYVAMUWZEOHJOQ-UHFFFAOYSA-N 0.000 claims description 2
• 150000005846 sugar alcohols Polymers 0.000 claims 2
• 150000001298 alcohols Chemical class 0.000 claims 1
• 239000007864 aqueous solution Substances 0.000 claims 1
• 239000000463 material Substances 0.000 claims 1
• 238000000465 moulding Methods 0.000 claims 1
• 230000003449 preventive effect Effects 0.000 claims 1
• 238000000034 method Methods 0.000 description 2