JP2017534604A5 - - Google Patents
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- JP2017534604A5 JP2017534604A5 JP2017518487A JP2017518487A JP2017534604A5 JP 2017534604 A5 JP2017534604 A5 JP 2017534604A5 JP 2017518487 A JP2017518487 A JP 2017518487A JP 2017518487 A JP2017518487 A JP 2017518487A JP 2017534604 A5 JP2017534604 A5 JP 2017534604A5
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- Japan
- Prior art keywords
- composition
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- sirolimus
- carrier
- micrograms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462060988P | 2014-10-07 | 2014-10-07 | |
| US62/060,988 | 2014-10-07 | ||
| US201562144145P | 2015-04-07 | 2015-04-07 | |
| US62/144,145 | 2015-04-07 | ||
| PCT/US2015/054550 WO2016057712A1 (en) | 2014-10-07 | 2015-10-07 | An inhalable rapamycin formulation for the treatment of pulmonary hypertension |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017534604A JP2017534604A (ja) | 2017-11-24 |
| JP2017534604A5 true JP2017534604A5 (enExample) | 2018-11-08 |
| JP6679584B2 JP6679584B2 (ja) | 2020-04-15 |
Family
ID=54360545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017518487A Active JP6679584B2 (ja) | 2014-10-07 | 2015-10-07 | 肺高血圧症を処置するための吸入可能なラパマイシン配合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20170304276A1 (enExample) |
| EP (1) | EP3209330B1 (enExample) |
| JP (1) | JP6679584B2 (enExample) |
| KR (1) | KR20170095807A (enExample) |
| CN (1) | CN107249576A (enExample) |
| AU (1) | AU2015330905B2 (enExample) |
| BR (1) | BR112017006842A2 (enExample) |
| CA (1) | CA2963085C (enExample) |
| IL (1) | IL251385B (enExample) |
| MX (1) | MX389399B (enExample) |
| RU (1) | RU2732908C2 (enExample) |
| WO (1) | WO2016057712A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6529012B2 (ja) | 2013-10-08 | 2019-06-12 | エイアイ・セラピューティクス・インコーポレーテッド | リンパ脈管筋腫症の処置のためのラパマイシン |
| NZ724756A (en) | 2014-04-04 | 2023-07-28 | Ai Therapeutics Inc | An inhalable rapamycin formulation for treating age-related conditions |
| RU2732908C2 (ru) | 2014-10-07 | 2020-09-24 | ЭйАй ТЕРАПЬЮТИКС, ИНК. | Ингаляционная лекарственная форма рапамицина для лечения легочной гипертензии |
| IL262720B2 (en) | 2016-05-05 | 2024-06-01 | Liquidia Tech Inc | Dry powder treprostinil for the treatment of pulmonary hypertension |
| ES2907692T3 (es) * | 2017-12-29 | 2022-04-26 | Celon Pharma Sa | Composición de ketamina de polvo seco para su administración por vía pulmonar en la depresión resistente al tratamiento |
| IL277402B1 (en) | 2018-03-20 | 2026-04-01 | Abraxis Bioscience Llc | Methods for treating central nervous system disorders using administration of MTOR inhibitor nanoparticles and albumin |
| TW202015659A (zh) * | 2018-05-22 | 2020-05-01 | 美商亞伯辛生物科學有限責任公司 | 用於治療肺高血壓之方法及組合物 |
| KR102936433B1 (ko) * | 2019-03-19 | 2026-03-09 | 아브락시스 바이오사이언스, 엘엘씨 | 질환의 치료를 위한 mTOR 억제제 및 알부민을 포함하는 나노입자의 피하 투여 |
| CN114072136B (zh) | 2019-04-29 | 2024-11-29 | 英斯梅德股份有限公司 | 曲前列素前药的干粉组合物及其使用方法 |
| CN113444730A (zh) * | 2021-03-17 | 2021-09-28 | 昆明市延安医院 | 一种原发性肝细胞klotho基因转导干细胞筛选构建方法 |
| WO2025220834A1 (ko) * | 2024-04-16 | 2025-10-23 | 한미약품 주식회사 | 흡입제 조성물 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2517482A (en) | 1949-04-09 | 1950-08-01 | Sharp & Dohme Inc | Inhaler |
| GB1242211A (en) | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
| ZA737247B (en) | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
| DE3345722A1 (de) | 1983-12-17 | 1985-06-27 | Boehringer Ingelheim KG, 6507 Ingelheim | Inhalator |
| GB8909891D0 (en) | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
| US5376386A (en) * | 1990-01-24 | 1994-12-27 | British Technology Group Limited | Aerosol carriers |
| US5080899A (en) | 1991-02-22 | 1992-01-14 | American Home Products Corporation | Method of treating pulmonary inflammation |
| DE4140689B4 (de) | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalationspulver und Verfahren zu ihrer Herstellung |
| AU688782B2 (en) | 1993-09-30 | 1998-03-19 | Wyeth | Rapamycin formulations for oral administration |
| NZ292980A (en) | 1994-09-29 | 1999-02-25 | Andaris Ltd | Smooth, spherical water-soluble microparticles as therapeutic or diagnostic vehicles |
| US5635161A (en) | 1995-06-07 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing vegetable oils |
| DE19523516C1 (de) * | 1995-06-30 | 1996-10-31 | Asta Medica Ag | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
| FR2736550B1 (fr) | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
| GB9606452D0 (en) | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
| AU735648B2 (en) | 1996-07-12 | 2001-07-12 | Ariad Pharmaceuticals, Inc. | Materials and method for treating or preventing pathogenic fungal infection |
| AU741439B2 (en) | 1996-12-30 | 2001-11-29 | Battelle Memorial Institute | Formulation and method for treating neoplasms by inhalation |
| US6451784B1 (en) | 1996-12-30 | 2002-09-17 | Battellepharma, Inc. | Formulation and method for treating neoplasms by inhalation |
| US5989591A (en) | 1997-03-14 | 1999-11-23 | American Home Products Corporation | Rapamycin formulations for oral administration |
| US20040039047A1 (en) | 1998-08-11 | 2004-02-26 | Mark Zamoyski | Compositions and methods for treating lung cancers |
| PT1104760E (pt) * | 1999-12-03 | 2003-06-30 | Pfizer Prod Inc | Compostos de sulfamoil-heteroarilpirazole como agentes analgesicos e anti-inflamatorios |
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| US6793912B2 (en) | 2001-08-20 | 2004-09-21 | Transave Inc. | Treatment of cancers by inhalation of stable platinum-containing formulations |
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| EP1506032A1 (en) | 2002-05-20 | 2005-02-16 | Research Development Foundation | Aerosol drug inhibition of lung metastases |
| US20050070567A1 (en) | 2002-08-12 | 2005-03-31 | The Regents Of The University Of Michigan | Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway |
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2015
- 2015-10-07 RU RU2017115990A patent/RU2732908C2/ru active
- 2015-10-07 KR KR1020177010965A patent/KR20170095807A/ko not_active Ceased
- 2015-10-07 CN CN201580066403.9A patent/CN107249576A/zh active Pending
- 2015-10-07 AU AU2015330905A patent/AU2015330905B2/en active Active
- 2015-10-07 EP EP15787076.7A patent/EP3209330B1/en active Active
- 2015-10-07 MX MX2017004440A patent/MX389399B/es unknown
- 2015-10-07 US US15/516,219 patent/US20170304276A1/en not_active Abandoned
- 2015-10-07 BR BR112017006842A patent/BR112017006842A2/pt not_active Application Discontinuation
- 2015-10-07 JP JP2017518487A patent/JP6679584B2/ja active Active
- 2015-10-07 CA CA2963085A patent/CA2963085C/en active Active
- 2015-10-07 WO PCT/US2015/054550 patent/WO2016057712A1/en not_active Ceased
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2017
- 2017-03-26 IL IL251385A patent/IL251385B/en unknown
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2019
- 2019-12-27 US US16/728,615 patent/US11491143B2/en active Active
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2022
- 2022-10-14 US US17/965,859 patent/US12611398B2/en active Active
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