JP2017533910A5 - - Google Patents
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- JP2017533910A5 JP2017533910A5 JP2017522852A JP2017522852A JP2017533910A5 JP 2017533910 A5 JP2017533910 A5 JP 2017533910A5 JP 2017522852 A JP2017522852 A JP 2017522852A JP 2017522852 A JP2017522852 A JP 2017522852A JP 2017533910 A5 JP2017533910 A5 JP 2017533910A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- polypeptide
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462072889P | 2014-10-30 | 2014-10-30 | |
| US62/072,889 | 2014-10-30 | ||
| PCT/US2015/058116 WO2016069925A1 (en) | 2014-10-30 | 2015-10-29 | Methods and compositions using gdf15 polypeptides for increasing red blood cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020023090A Division JP7154241B2 (ja) | 2014-10-30 | 2020-02-14 | Ｇｄｆ１５ポリペプチドを使用する、赤血球を増加させるための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017533910A JP2017533910A (ja) | 2017-11-16 |
| JP2017533910A5 true JP2017533910A5 (enExample) | 2018-12-06 |
| JP6663428B2 JP6663428B2 (ja) | 2020-03-11 |
Family
ID=55858354
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017522852A Expired - Fee Related JP6663428B2 (ja) | 2014-10-30 | 2015-10-29 | Ｇｄｆ１５ポリペプチドを使用する、赤血球を増加させるための方法および組成物 |
| JP2020023090A Expired - Fee Related JP7154241B2 (ja) | 2014-10-30 | 2020-02-14 | Ｇｄｆ１５ポリペプチドを使用する、赤血球を増加させるための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020023090A Expired - Fee Related JP7154241B2 (ja) | 2014-10-30 | 2020-02-14 | Ｇｄｆ１５ポリペプチドを使用する、赤血球を増加させるための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10603359B2 (enExample) |
| EP (2) | EP3922259B1 (enExample) |
| JP (2) | JP6663428B2 (enExample) |
| AU (2) | AU2015339134B2 (enExample) |
| CA (1) | CA2964808C (enExample) |
| WO (1) | WO2016069925A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| AU2015339134B2 (en) * | 2014-10-30 | 2021-06-17 | Acceleron Pharma Inc. | Methods and compositions using GDF15 polypeptides for increasing red blood cells |
| EP3370754B1 (en) | 2015-11-04 | 2026-04-29 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating ineffective erythropoiesis |
| US10336812B2 (en) * | 2016-05-10 | 2019-07-02 | Janssen Biotech, Inc. | GDF15 fusion proteins and uses thereof |
| KR102433503B1 (ko) | 2016-05-24 | 2022-08-18 | 노보 노르디스크 에이/에스 | Mic-1 화합물 및 이것의 사용 |
| TWI724392B (zh) | 2018-04-06 | 2021-04-11 | 美商美國禮來大藥廠 | 生長分化因子15促效劑化合物及其使用方法 |
| MY205905A (en) | 2018-10-22 | 2024-11-20 | Janssen Pharmaceutica Nv | Glucagon like peptide 1 (glp1)-growth differentiation factor 15 (gdf15) fusion proteins and uses thereof |
| CA3161302A1 (en) * | 2019-11-26 | 2021-06-03 | Yuhan Corporation | Long-acting gdf15 fusion protein and pharmaceutical composition comprising same |
| US12209112B2 (en) * | 2022-09-15 | 2025-01-28 | The Chinese University Of Hong Kong | Methods of preventing or treating diseases, conditions, or disorders associated with chemotherapy |
| CN119386165A (zh) * | 2024-12-19 | 2025-02-07 | 郑州大学 | Gdf15在制备治疗don中毒的药物中的应用及其药物 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63502716A (ja) | 1986-03-07 | 1988-10-13 | マサチューセッツ・インステチュート・オブ・テクノロジー | 糖タンパク安定性の強化方法 |
| US4965251A (en) * | 1987-04-03 | 1990-10-23 | The Board Of Regents Of The University Of Washington | Pulse treatment of hemoglobinopathies with erythropoietin |
| WO1990008822A1 (en) | 1989-02-03 | 1990-08-09 | Genetics Institute, Inc. | Erythropoietin receptor |
| US5885574A (en) | 1994-07-26 | 1999-03-23 | Amgen Inc. | Antibodies which activate an erythropoietin receptor |
| US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| JP2002523044A (ja) | 1998-08-21 | 2002-07-30 | プリンストン ユニバーシティー | 血液を形成する造血幹細胞を調節する遺伝子およびその使用 |
| CA2672758C (en) | 2006-12-18 | 2019-07-30 | Acceleron Pharma Inc. | Activin-actrii antagonists and uses for increasing red blood cell levels |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| DK3750552T5 (da) | 2008-08-14 | 2024-08-26 | Acceleron Pharma Inc | Gdf-fælder |
| CA2740632A1 (en) * | 2008-10-31 | 2010-05-06 | St. Vincent's Hospital Sydney Limited | Methods of prognosis in chronic kidney disease |
| KR102170682B1 (ko) * | 2009-08-13 | 2020-10-28 | 악셀레론 파마 인코포레이티드 | 적혈구 수준을 증가시키기 위한 ｇｄｆ 트랩과 에리트로포이에틴 수용체 활성인자의 병용 |
| KR102104401B1 (ko) * | 2011-03-29 | 2020-04-27 | 알닐람 파마슈티칼스 인코포레이티드 | Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법 |
| WO2013078253A1 (en) | 2011-11-22 | 2013-05-30 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| MX357708B (es) * | 2011-12-14 | 2018-07-20 | Abbvie Deutschland | Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro. |
| KR20140125803A (ko) * | 2012-01-26 | 2014-10-29 | 암젠 인크 | 성장 분화 인자 15(gdf-15) 폴리펩타이드들 |
| EP2644278B1 (en) | 2012-03-27 | 2014-12-10 | Alfa Laval Corporate AB | Centrifugal separator and method of controlling intermittent discharge |
| ES3066738T3 (en) | 2012-12-21 | 2026-05-14 | Aveo Pharmaceuticals Inc | Anti-gdf15 antibodies |
| CA2899170C (en) * | 2013-01-30 | 2022-08-02 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use in treating metabolic disorders |
| US9161966B2 (en) | 2013-01-30 | 2015-10-20 | Ngm Biopharmaceuticals, Inc. | GDF15 mutein polypeptides |
| HRP20201914T1 (hr) * | 2013-05-06 | 2021-01-22 | Scholar Rock, Inc. | Sastavi i postupci za modulaciju faktora rasta |
| HK1225742A1 (zh) | 2013-08-22 | 2017-09-15 | Acceleron Pharma, Inc. | TGF-β受体II型变体及其用途 |
| JP2017509647A (ja) | 2014-03-21 | 2017-04-06 | アクセルロン ファーマ， インコーポレイテッド | アクチビンｂおよび／またはｇｄｆ１１の阻害によって赤血球レベルを増大させ、無効赤血球生成を処置する方法 |
| CA2952032C (en) * | 2014-06-20 | 2023-03-14 | Aveo Pharmaceuticals, Inc. | Treatment of chronic kidney disease and other renal dysfunction using a gdf15 modulator |
| AU2015339134B2 (en) * | 2014-10-30 | 2021-06-17 | Acceleron Pharma Inc. | Methods and compositions using GDF15 polypeptides for increasing red blood cells |
| TWI621976B (zh) | 2015-07-24 | 2018-04-21 | 瑞鼎科技股份有限公司 | 內嵌式觸控面板驅動方法 |
| AU2017228489A1 (en) * | 2016-03-04 | 2018-09-06 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for modulating body weight |
-
2015
- 2015-10-29 AU AU2015339134A patent/AU2015339134B2/en not_active Ceased
- 2015-10-29 CA CA2964808A patent/CA2964808C/en active Active
- 2015-10-29 JP JP2017522852A patent/JP6663428B2/ja not_active Expired - Fee Related
- 2015-10-29 EP EP21170026.5A patent/EP3922259B1/en active Active
- 2015-10-29 US US15/523,025 patent/US10603359B2/en active Active
- 2015-10-29 EP EP15854065.8A patent/EP3212213B1/en active Active
- 2015-10-29 WO PCT/US2015/058116 patent/WO2016069925A1/en not_active Ceased
-
2020
- 2020-02-14 JP JP2020023090A patent/JP7154241B2/ja not_active Expired - Fee Related
- 2020-02-28 US US16/804,459 patent/US11642394B2/en active Active
-
2021
- 2021-09-14 AU AU2021232680A patent/AU2021232680A1/en not_active Abandoned
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