JP2017532378A5 - - Google Patents
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- JP2017532378A5 JP2017532378A5 JP2017538918A JP2017538918A JP2017532378A5 JP 2017532378 A5 JP2017532378 A5 JP 2017532378A5 JP 2017538918 A JP2017538918 A JP 2017538918A JP 2017538918 A JP2017538918 A JP 2017538918A JP 2017532378 A5 JP2017532378 A5 JP 2017532378A5
- Authority
- JP
- Japan
- Prior art keywords
- phospholipid
- polymer
- liposome composition
- aromatic
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462061514P | 2014-10-08 | 2014-10-08 | |
| US62/061,514 | 2014-10-08 | ||
| US201562111057P | 2015-02-02 | 2015-02-02 | |
| US62/111,057 | 2015-02-02 | ||
| PCT/US2015/054732 WO2016057812A1 (en) | 2014-10-08 | 2015-10-08 | Mri imaging of amyloid plaque using liposomes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017532378A JP2017532378A (ja) | 2017-11-02 |
| JP2017532378A5 true JP2017532378A5 (enExample) | 2018-11-22 |
| JP6505235B2 JP6505235B2 (ja) | 2019-04-24 |
Family
ID=55653789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538918A Active JP6505235B2 (ja) | 2014-10-08 | 2015-10-08 | リポソームを用いるアミロイド斑のmriイメージング |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9744251B2 (enExample) |
| EP (3) | EP3204051B1 (enExample) |
| JP (1) | JP6505235B2 (enExample) |
| KR (1) | KR102409017B1 (enExample) |
| CN (1) | CN107106708B (enExample) |
| AU (2) | AU2015330824A1 (enExample) |
| CA (1) | CA2963941C (enExample) |
| ES (2) | ES2743704T3 (enExample) |
| MX (1) | MX371295B (enExample) |
| WO (1) | WO2016057812A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012139080A2 (en) | 2011-04-06 | 2012-10-11 | Board Of Regents Of The University Of Texas System | Lipid-based nanoparticles |
| CA2848994A1 (en) | 2012-01-20 | 2013-07-25 | Ananth Annapragada | Methods and compositions for objectively characterizing medical images |
| EP3204051B1 (en) | 2014-10-08 | 2019-05-29 | Texas Children's Hospital | Mri imaging of amyloid plaque using liposomes |
| WO2018015546A1 (en) | 2016-07-22 | 2018-01-25 | Ac Immune S.A. | Compounds for imaging tau protein aggregates |
| KR102472003B1 (ko) | 2016-07-22 | 2022-11-29 | 에이씨 이뮨 에스에이 | 타우 단백질 응집체를 이미징하기 위한 화합물 |
| EP3512570B1 (en) * | 2016-09-16 | 2024-08-28 | Texas Children's Hospital | Liposomal gadolinium (gd) contrast agent for t1-mri |
| US11241510B2 (en) | 2016-11-30 | 2022-02-08 | Texas Children's Hospital | Hydrophilic fluorinated molecules for liposomal 19F MRI probes with unique MR signatures |
| EP3743423A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Gamma-carboline compounds for the detection of tau aggregates |
| US20210041447A1 (en) | 2018-01-24 | 2021-02-11 | Ac Immune Sa | Azacarboline compounds for the detection of tau aggregates |
| CN116173238A (zh) * | 2018-03-29 | 2023-05-30 | 微脉管治疗有限公司 | 用于检测和治疗阿尔茨海默病的组合物及方法 |
| WO2019234243A1 (en) | 2018-06-08 | 2019-12-12 | Ac Immune Sa | Novel compounds for diagnosis |
| JP7545393B2 (ja) * | 2019-01-24 | 2024-09-04 | アルゼカ バイオサイエンシズ、エルエルシー | 誤って折りたたまれたタンパク質を画像化するための機能化リポソーム |
| US20210128755A1 (en) * | 2019-07-08 | 2021-05-06 | Alzeca Biosciences, LLC | Targeting ligands for tau pathology |
| US11614451B2 (en) | 2019-07-08 | 2023-03-28 | Alzeca Biosciences, LLC | Targeting ligands for tau pathology |
| CN115916263B (zh) * | 2020-01-29 | 2025-10-03 | 德克萨斯儿童医院 | 用于淀粉样蛋白沉积mri的靶向对比剂 |
| US11779664B2 (en) | 2020-02-12 | 2023-10-10 | Texas Children's Hospital | Targeted contrast agents for MRI of alpha-synuclein deposition |
| CN115279424A (zh) * | 2020-02-12 | 2022-11-01 | 德克萨斯儿童医院 | 用于α-突触核蛋白沉积MRI的靶向对比剂 |
| CN115970009A (zh) * | 2023-02-08 | 2023-04-18 | 丽水市中心医院 | Vhpk多肽修饰的荧光纳米脂质体给药系统、其制备方法及应用 |
| CN116869938A (zh) * | 2023-07-26 | 2023-10-13 | 安徽医科大学 | 一种1,2,4-噁二唑-吡啶脂质体及其制备方法和应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204085A (en) | 1985-01-08 | 1993-04-20 | Mallinckrodt Medical, Inc. | Method for enhancing the safety of metal-ligand chelates as X-ray contrast agents |
| DE69527194T2 (de) | 1994-03-28 | 2003-02-06 | Daiichi Pharmaceutical Co., Ltd. | Liposomen enthaltend ein röntgen- oder ultraschallkontrastmittel |
| US6071532A (en) * | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
| JP4829454B2 (ja) | 1999-11-30 | 2011-12-07 | ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティ・オブ・アリゾナ | 放射線感受性リポソーム |
| AU2002211517A1 (en) | 2000-10-04 | 2002-04-15 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
| WO2002094191A2 (en) | 2001-05-23 | 2002-11-28 | New York University | Detection of alzheimer's amyloid by magnetic resonance imaging |
| JP2005519129A (ja) | 2002-03-05 | 2005-06-30 | クリーブランド ステート ユニバーシティー | エアロゾル薬物送達のための凝集粒子 |
| WO2004096120A2 (en) * | 2003-05-01 | 2004-11-11 | Nst Neurosurvival Technologies Ltd. | Compounds that selectively bind to membranes of apoptotic cells |
| US7208174B2 (en) | 2003-12-18 | 2007-04-24 | Hoffmann-La Roche Inc. | Liposome compositions |
| US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
| US7713517B2 (en) | 2004-04-21 | 2010-05-11 | Marval Biosciences, Inc. | Compositions and methods for enhancing contrast in imaging |
| US8357351B2 (en) | 2004-04-21 | 2013-01-22 | Ananth Annapragada | Nano-scale contrast agents and methods of use |
| US20070292354A1 (en) | 2004-09-23 | 2007-12-20 | Guerbet | Contrast Agents Encapsulating Systems for Cest Imaging |
| WO2007041855A1 (en) | 2005-10-13 | 2007-04-19 | Waratah Pharmaceuticals, Inc. | Scyllo-inositol derivatives and their use in the treatment of diseases characterised by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
| WO2007048019A2 (en) | 2005-10-20 | 2007-04-26 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
| US20090123047A1 (en) | 2007-03-21 | 2009-05-14 | Yfantis Spyros A | Method and system for characterizing prostate images |
| EP1982733A1 (en) | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
| US7858803B2 (en) | 2007-04-27 | 2010-12-28 | The General Hospital Corporation | Imaging tracers for early detection and treatment of amyloid plaques caused by Alzheimer's disease and related disorders |
| WO2009015397A1 (en) | 2007-07-26 | 2009-01-29 | Nanoscan Imaging, Llc | Methods for imaging using improved nanoparticulate contrast agents |
| US8642013B2 (en) | 2007-12-05 | 2014-02-04 | Ananth Annapragada | Nano-scale contrast agents and methods of use |
| CA2711503A1 (en) * | 2008-01-08 | 2009-07-16 | Biogenerix Ag | Glycoconjugation of polypeptides using oligosaccharyltransferases |
| ITMI20081052A1 (it) | 2008-06-10 | 2009-12-11 | Univ Milano Bicocca | Liposomi in grado di legare efficacemente il peptide beta-amiloide |
| AU2009257279A1 (en) | 2008-06-13 | 2009-12-17 | Marval Biosciences, Inc. | Imaging of atherosclerotic plaques using liposomal imaging agents |
| WO2010017094A2 (en) | 2008-07-31 | 2010-02-11 | The General Hospital Corporation | CURCUMIN DERIVATIVES FOR AMYLOID-β PLAQUE IMAGING |
| AR074760A1 (es) | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| CN102438591A (zh) | 2009-03-19 | 2012-05-02 | 马维尔生物科学公司 | 用于增强成像对比度的组合物和方法 |
| US20120263646A1 (en) | 2009-10-15 | 2012-10-18 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
| ES2526124T3 (es) | 2010-06-16 | 2015-01-07 | Cymabay Therapeutics, Inc. | Agonistas del receptor GPR120 y sus usos |
| CN103429226A (zh) | 2011-03-02 | 2013-12-04 | 森苏林公司 | 囊泡组合物 |
| WO2012139080A2 (en) * | 2011-04-06 | 2012-10-11 | Board Of Regents Of The University Of Texas System | Lipid-based nanoparticles |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
| CA2848994A1 (en) | 2012-01-20 | 2013-07-25 | Ananth Annapragada | Methods and compositions for objectively characterizing medical images |
| US9377472B2 (en) | 2012-04-30 | 2016-06-28 | Amoneta Diagnostics | Biological complex specific for Alzheimer's disease detection in vitro and use thereof |
| CA2906035A1 (en) | 2013-03-14 | 2014-09-25 | Celtaxsys, Inc. | Inhibitors of leukotriene a4 hydrolase |
| EP3204051B1 (en) | 2014-10-08 | 2019-05-29 | Texas Children's Hospital | Mri imaging of amyloid plaque using liposomes |
-
2015
- 2015-10-08 EP EP15849750.3A patent/EP3204051B1/en active Active
- 2015-10-08 JP JP2017538918A patent/JP6505235B2/ja active Active
- 2015-10-08 MX MX2017004695A patent/MX371295B/es active IP Right Grant
- 2015-10-08 US US14/878,745 patent/US9744251B2/en active Active
- 2015-10-08 ES ES15849750T patent/ES2743704T3/es active Active
- 2015-10-08 CN CN201580066712.6A patent/CN107106708B/zh active Active
- 2015-10-08 CA CA2963941A patent/CA2963941C/en active Active
- 2015-10-08 ES ES22152987T patent/ES3032054T3/es active Active
- 2015-10-08 EP EP19172751.0A patent/EP3542828A1/en not_active Withdrawn
- 2015-10-08 KR KR1020177012354A patent/KR102409017B1/ko active Active
- 2015-10-08 EP EP22152987.8A patent/EP4035688B1/en active Active
- 2015-10-08 WO PCT/US2015/054732 patent/WO2016057812A1/en not_active Ceased
- 2015-10-08 AU AU2015330824A patent/AU2015330824A1/en not_active Abandoned
-
2016
- 2016-12-01 US US15/366,667 patent/US10537649B2/en active Active
-
2019
- 2019-11-08 US US16/677,751 patent/US20200069820A1/en not_active Abandoned
-
2020
- 2020-02-14 US US16/791,068 patent/US11141495B2/en active Active
-
2021
- 2021-05-25 AU AU2021203388A patent/AU2021203388B2/en active Active
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