JP2017531028A5 - - Google Patents
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- JP2017531028A5 JP2017531028A5 JP2017526774A JP2017526774A JP2017531028A5 JP 2017531028 A5 JP2017531028 A5 JP 2017531028A5 JP 2017526774 A JP2017526774 A JP 2017526774A JP 2017526774 A JP2017526774 A JP 2017526774A JP 2017531028 A5 JP2017531028 A5 JP 2017531028A5
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- binding agent
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- 239000011230 binding agent Substances 0.000 claims description 65
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims description 56
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- 101710089372 Programmed cell death protein 1 Proteins 0.000 claims description 17
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462033177P | 2014-08-05 | 2014-08-05 | |
| US62/033,177 | 2014-08-05 | ||
| US201462053366P | 2014-09-22 | 2014-09-22 | |
| US62/053,366 | 2014-09-22 | ||
| US201462093368P | 2014-12-17 | 2014-12-17 | |
| US62/093,368 | 2014-12-17 | ||
| PCT/IB2015/055943 WO2016020856A2 (en) | 2014-08-05 | 2015-08-05 | Immunological reagents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531028A JP2017531028A (ja) | 2017-10-19 |
| JP2017531028A5 true JP2017531028A5 (cg-RX-API-DMAC7.html) | 2018-09-20 |
| JP6629321B2 JP6629321B2 (ja) | 2020-01-15 |
Family
ID=53836144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017526774A Active JP6629321B2 (ja) | 2014-08-05 | 2015-08-05 | 免疫学的試薬 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9982053B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3177644B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6629321B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102357893B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107074947B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015298356B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2957258C (cg-RX-API-DMAC7.html) |
| DK (1) | DK3177644T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2847311T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL3177644T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT3177644T (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201700672YA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016020856A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (138)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202442680A (zh) | 2008-12-09 | 2024-11-01 | 美商建南德克公司 | 抗pd-l1抗體及其於增進t細胞功能之用途 |
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| ES2845609T3 (es) | 2013-05-02 | 2021-07-27 | Anaptysbio Inc | Anticuerpos dirigidos contra muerte programada-1 (PD-1) |
| TWI693232B (zh) | 2014-06-26 | 2020-05-11 | 美商宏觀基因股份有限公司 | 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法 |
| US9982052B2 (en) * | 2014-08-05 | 2018-05-29 | MabQuest, SA | Immunological reagents |
| PL3177644T3 (pl) * | 2014-08-05 | 2021-06-14 | MabQuest SA | Immunologiczne reagenty wiążące do PD-1 |
| RS62332B1 (sr) | 2014-11-26 | 2021-10-29 | Xencor Inc | Heterodimerna antitela koja vezuju cd3 i cd20 |
| HRP20201031T1 (hr) | 2015-05-29 | 2020-10-16 | Agenus Inc. | Anti-ctla-4 protutijela i postupci njihove upotrebe |
| TWI773646B (zh) | 2015-06-08 | 2022-08-11 | 美商宏觀基因股份有限公司 | 結合lag-3的分子和其使用方法 |
| WO2017011580A2 (en) | 2015-07-13 | 2017-01-19 | Cytomx Therapeutics, Inc. | Anti-pd-1 antibodies, activatable anti-pd-1 antibodies, and methods of use thereof |
| ES2898958T3 (es) | 2015-07-30 | 2022-03-09 | Macrogenics Inc | Moléculas de unión a PD-1 y LAG-3 y métodos de uso de las mismas |
| CN108289953B (zh) | 2015-09-29 | 2022-03-11 | 细胞基因公司 | Pd-1结合蛋白及其使用方法 |
| MA43186B1 (fr) | 2015-11-03 | 2022-03-31 | Janssen Biotech Inc | Anticorps se liant spécifiquement à pd-1 et leurs utilisations |
| MA44082A (fr) | 2015-12-14 | 2018-10-24 | Macrogenics Inc | Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation |
| US11214617B2 (en) * | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| EP3405497A2 (en) | 2016-01-22 | 2018-11-28 | Mabquest SA | Immunological reagents |
| CN106008714B (zh) * | 2016-05-24 | 2019-03-15 | 瑞阳(苏州)生物科技有限公司 | 抗人pd-1人源化单克隆抗体及其应用 |
| CA3024508A1 (en) | 2016-05-27 | 2017-11-30 | Agenus Inc. | Anti-tim-3 antibodies and methods of use thereof |
| IL263542B2 (en) * | 2016-06-14 | 2024-10-01 | Xencor Inc | Bispecific antibodies inhibit immunological checkpoint |
| BR112019004733A2 (pt) | 2016-09-19 | 2019-05-28 | Celgene Corp | métodos de tratamento de distúrbios imunes usando proteínas de ligação a pd-1 |
| US10766958B2 (en) | 2016-09-19 | 2020-09-08 | Celgene Corporation | Methods of treating vitiligo using PD-1 binding antibodies |
| WO2018071500A1 (en) | 2016-10-11 | 2018-04-19 | Agenus Inc. | Anti-lag-3 antibodies and methods of use thereof |
| EP3534950A4 (en) | 2016-11-01 | 2020-05-06 | AnaptysBio, Inc. | Antibodies directed against programmed death- 1 (pd-1) |
| SI3535298T1 (sl) * | 2016-11-02 | 2022-01-31 | Jounce Therapeutics, Inc. | Protitelesa proti pd-1 in njihove uporabe |
| US11013802B2 (en) | 2016-12-07 | 2021-05-25 | Agenus Inc. | Anti-CTLA-4 antibodies and methods of use thereof |
| AU2017373945B2 (en) | 2016-12-07 | 2025-01-23 | Agenus Inc. | Antibodies and methods of use thereof |
| US11591398B2 (en) | 2017-01-06 | 2023-02-28 | Crescendo Biologics Limited | Single domain antibodies to programmed cell death protein 1 (PD-1) |
| MX2019008207A (es) | 2017-01-09 | 2019-12-11 | Tesaro Inc | Métodos para tratar el cáncer con anticuerpos anti-pd-1. |
| KR20190103226A (ko) | 2017-01-13 | 2019-09-04 | 아게누스 인코포레이티드 | Ny-eso-1에 결합하는 t 세포 수용체 및 이의 사용 방법 |
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| PT2699264T (pt) | 2011-04-20 | 2018-05-23 | Medimmune Llc | Anticorpos e outras moléculas que ligam b7-h1 e pd-1 |
| US9090994B2 (en) | 2011-06-08 | 2015-07-28 | Nanjingjinsirui Science & Technology Biology Corp. | Antibody humanization by framework assembly |
| TWI835048B (zh) * | 2011-08-01 | 2024-03-11 | 美商建南德克公司 | 利用pd-1軸結合拮抗劑及mek抑制劑治療癌症之方法 |
| WO2013043569A1 (en) | 2011-09-20 | 2013-03-28 | Vical Incorporated | Synergistic anti-tumor efficacy using alloantigen combination immunotherapy |
| EP2817619B1 (en) * | 2012-02-23 | 2018-07-25 | Sloan Kettering Institute For Cancer Research | Prediction of responsiveness to treatment with immunomodulatory therapeutics and method of monitoring abscopal effects during such treatment |
| WO2013169693A1 (en) | 2012-05-09 | 2013-11-14 | Bristol-Myers Squibb Company | Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody |
| EP2904011B1 (en) * | 2012-10-02 | 2017-08-23 | Bristol-Myers Squibb Company | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| ES2845609T3 (es) | 2013-05-02 | 2021-07-27 | Anaptysbio Inc | Anticuerpos dirigidos contra muerte programada-1 (PD-1) |
| CN104250302B (zh) | 2013-06-26 | 2017-11-14 | 上海君实生物医药科技股份有限公司 | 抗pd‑1抗体及其应用 |
| EA034666B1 (ru) * | 2013-09-13 | 2020-03-04 | Бейджин Свитзерланд Гмбх | Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| PL3177644T3 (pl) * | 2014-08-05 | 2021-06-14 | MabQuest SA | Immunologiczne reagenty wiążące do PD-1 |
| US9982052B2 (en) * | 2014-08-05 | 2018-05-29 | MabQuest, SA | Immunological reagents |
| US10239942B2 (en) | 2014-12-22 | 2019-03-26 | Pd-1 Acquisition Group, Llc | Anti-PD-1 antibodies |
| US11214617B2 (en) * | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| EP3405497A2 (en) * | 2016-01-22 | 2018-11-28 | Mabquest SA | Immunological reagents |
-
2015
- 2015-08-05 PL PL15750136T patent/PL3177644T3/pl unknown
- 2015-08-05 WO PCT/IB2015/055943 patent/WO2016020856A2/en not_active Ceased
- 2015-08-05 ES ES15750136T patent/ES2847311T3/es active Active
- 2015-08-05 EP EP15750136.2A patent/EP3177644B1/en active Active
- 2015-08-05 PT PT157501362T patent/PT3177644T/pt unknown
- 2015-08-05 AU AU2015298356A patent/AU2015298356B2/en active Active
- 2015-08-05 KR KR1020177004575A patent/KR102357893B1/ko active Active
- 2015-08-05 JP JP2017526774A patent/JP6629321B2/ja active Active
- 2015-08-05 US US15/329,760 patent/US9982053B2/en active Active
- 2015-08-05 CA CA2957258A patent/CA2957258C/en active Active
- 2015-08-05 SG SG11201700672YA patent/SG11201700672YA/en unknown
- 2015-08-05 CN CN201580042199.7A patent/CN107074947B/zh active Active
- 2015-08-05 DK DK15750136.2T patent/DK3177644T3/da active
-
2018
- 2018-05-17 US US15/981,977 patent/US11130807B2/en active Active
-
2021
- 2021-09-27 US US17/485,752 patent/US20220169733A1/en not_active Abandoned
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