JP2017530718A5 - - Google Patents
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- Publication number
- JP2017530718A5 JP2017530718A5 JP2017520418A JP2017520418A JP2017530718A5 JP 2017530718 A5 JP2017530718 A5 JP 2017530718A5 JP 2017520418 A JP2017520418 A JP 2017520418A JP 2017520418 A JP2017520418 A JP 2017520418A JP 2017530718 A5 JP2017530718 A5 JP 2017530718A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- recombinant expression
- expression vector
- nucleic acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013604 expression vector Substances 0.000 claims 10
- 238000003259 recombinant expression Methods 0.000 claims 10
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical group 0.000 claims 7
- 230000001105 regulatory effect Effects 0.000 claims 6
- 102100031181 Glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 241000699800 Cricetinae Species 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462064335P | 2014-10-15 | 2014-10-15 | |
| US62/064,335 | 2014-10-15 | ||
| PCT/US2015/055549 WO2016061240A1 (en) | 2014-10-15 | 2015-10-14 | Promoter and regulatory elements for improved expression of heterologous genes in host cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530718A JP2017530718A (ja) | 2017-10-19 |
| JP2017530718A5 true JP2017530718A5 (https=) | 2018-11-22 |
| JP6749898B2 JP6749898B2 (ja) | 2020-09-02 |
Family
ID=54541176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017520418A Active JP6749898B2 (ja) | 2014-10-15 | 2015-10-14 | 宿主細胞における異種由来遺伝子の発現を改善するためのプロモーター及び調節エレメント |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10202616B2 (https=) |
| EP (2) | EP3207146B1 (https=) |
| JP (1) | JP6749898B2 (https=) |
| AU (1) | AU2015332577B2 (https=) |
| CA (1) | CA2964313C (https=) |
| ES (2) | ES2900331T3 (https=) |
| MX (1) | MX377591B (https=) |
| WO (1) | WO2016061240A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2768186A1 (en) | 2009-07-15 | 2011-01-20 | Novartis Ag | Rsv f protein compositions and methods for making same |
| CA2835644C (en) | 2011-05-13 | 2021-06-15 | Novartis Ag | Pre-fusion rsv f antigens |
| TW202233660A (zh) | 2020-10-30 | 2022-09-01 | 美商安進公司 | 過表現胰島素樣生長因子受體突變體以調節ｉｇｆ補充 |
| CN114196703B (zh) * | 2021-12-22 | 2023-02-03 | 西北农林科技大学 | 一种提高牦牛克隆胚胎发育率的载体、细胞和方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US30985A (en) | 1860-12-18 | Thomas l | ||
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| EP0387319B1 (en) | 1988-07-23 | 1996-03-06 | Delta Biotechnology Limited | Secretory leader sequences |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| WO1996033735A1 (en) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| GB9022543D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| WO1993016177A1 (en) | 1992-02-11 | 1993-08-19 | Cell Genesys, Inc. | Homogenotization of gene-targeting events |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| ES2301158T3 (es) | 1992-07-24 | 2008-06-16 | Amgen Fremont Inc. | Produccion de anticuerpos xenogenicos. |
| US6054287A (en) | 1994-05-27 | 2000-04-25 | Methodist Hospital Of Indiana, Inc. | Cell-type-specific methods and devices for the low temperature preservation of the cells of an animal species |
| US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| GB9712818D0 (en) | 1996-07-08 | 1997-08-20 | Cambridge Antibody Tech | Labelling and selection of specific binding molecules |
| CA2722378C (en) | 1996-12-03 | 2015-02-03 | Amgen Fremont Inc. | Human antibodies that bind tnf.alpha. |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| US20030044772A1 (en) | 1997-08-04 | 2003-03-06 | Applied Molecular Evolution [Formerly Ixsys] | Methods for identifying ligand specific binding molecules |
| US6022952A (en) | 1998-04-01 | 2000-02-08 | University Of Alberta | Compositions and methods for protein secretion |
| US20020029391A1 (en) | 1998-04-15 | 2002-03-07 | Claude Geoffrey Davis | Epitope-driven human antibody production and gene expression profiling |
| US6210924B1 (en) | 1998-08-11 | 2001-04-03 | Amgen Inc. | Overexpressing cyclin D 1 in a eukaryotic cell line |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| JP4475814B2 (ja) | 1998-11-20 | 2010-06-09 | 扶桑薬品工業株式会社 | タンパク質発現ベクターとその使用 |
| AU4010400A (en) | 1999-03-18 | 2000-10-04 | Human Genome Sciences, Inc. | 27 human secreted proteins |
| CA2430013C (en) | 2000-11-30 | 2011-11-22 | Medarex, Inc. | Transgenic transchromosomal rodents for making human antibodies |
| US20040257396A1 (en) | 2003-06-19 | 2004-12-23 | Toshiba Tec Kabushiki Kaisha | Ink jet head cleaning apparatus and ink jet recording apparatus |
| GB0509965D0 (en) * | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| TW200722436A (en) | 2005-10-21 | 2007-06-16 | Hoffmann La Roche | A peptide-immunoglobulin-conjugate |
| JP2010525789A (ja) * | 2007-01-08 | 2010-07-29 | ミリポア・コーポレイション | １つ又はそれ以上のきょう雑物の低下したレベルの存在下で組換えタンパク質を生産するための細胞培養法 |
| HK1202578A1 (en) * | 2011-12-07 | 2015-10-02 | Ichnos Sciences SA | Expression cassette |
-
2015
- 2015-10-14 MX MX2017004769A patent/MX377591B/es active IP Right Grant
- 2015-10-14 AU AU2015332577A patent/AU2015332577B2/en active Active
- 2015-10-14 ES ES15794369T patent/ES2900331T3/es active Active
- 2015-10-14 US US15/519,820 patent/US10202616B2/en active Active
- 2015-10-14 EP EP15794369.7A patent/EP3207146B1/en active Active
- 2015-10-14 JP JP2017520418A patent/JP6749898B2/ja active Active
- 2015-10-14 EP EP20173389.6A patent/EP3722433B1/en active Active
- 2015-10-14 WO PCT/US2015/055549 patent/WO2016061240A1/en not_active Ceased
- 2015-10-14 CA CA2964313A patent/CA2964313C/en active Active
- 2015-10-14 ES ES20173389T patent/ES2962385T3/es active Active
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