JP2017530124A5 - - Google Patents
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- Publication number
- JP2017530124A5 JP2017530124A5 JP2017516077A JP2017516077A JP2017530124A5 JP 2017530124 A5 JP2017530124 A5 JP 2017530124A5 JP 2017516077 A JP2017516077 A JP 2017516077A JP 2017516077 A JP2017516077 A JP 2017516077A JP 2017530124 A5 JP2017530124 A5 JP 2017530124A5
- Authority
- JP
- Japan
- Prior art keywords
- fmdv
- composition
- vaccine
- antigen
- viral vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims 27
- 239000000203 mixture Substances 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 16
- 102000036639 antigens Human genes 0.000 claims 16
- 108091007433 antigens Proteins 0.000 claims 16
- 229960005486 vaccine Drugs 0.000 claims 13
- 239000013603 viral vector Substances 0.000 claims 10
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 239000002157 polynucleotide Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 241000238631 Hexapoda Species 0.000 claims 3
- 238000001727 in vivo Methods 0.000 claims 3
- 239000013612 plasmid Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 206010061818 Disease progression Diseases 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 235000018417 cysteine Nutrition 0.000 claims 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 2
- 230000005750 disease progression Effects 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 241000701161 unidentified adenovirus Species 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000005215 recombination Methods 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
- 241000701447 unidentified baculovirus Species 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
- 239000003981 vehicle Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462054073P | 2014-09-23 | 2014-09-23 | |
| US62/054,073 | 2014-09-23 | ||
| PCT/US2015/051755 WO2016049209A1 (en) | 2014-09-23 | 2015-09-23 | Fmdv recombinant vaccines and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530124A JP2017530124A (ja) | 2017-10-12 |
| JP2017530124A5 true JP2017530124A5 (cg-RX-API-DMAC7.html) | 2018-11-01 |
| JP6931327B2 JP6931327B2 (ja) | 2021-09-01 |
Family
ID=54256845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017516077A Active JP6931327B2 (ja) | 2014-09-23 | 2015-09-23 | Ｆｍｄｖ組換えワクチンおよびその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10010605B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3197486A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6931327B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102526219B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107073100B (cg-RX-API-DMAC7.html) |
| AP (1) | AP2017009834A0 (cg-RX-API-DMAC7.html) |
| AR (1) | AR102006A1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2015320673B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2962225A1 (cg-RX-API-DMAC7.html) |
| JO (1) | JO3600B1 (cg-RX-API-DMAC7.html) |
| MA (1) | MA40151B2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX388708B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2745373C2 (cg-RX-API-DMAC7.html) |
| TW (1) | TWI733653B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016049209A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201701851B (cg-RX-API-DMAC7.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10391163B2 (en) | 2015-09-10 | 2019-08-27 | Academia Sinica | Bird flu vaccine combination comprising virus-like particles and novel adjuvants |
| MA43310A (fr) | 2015-11-23 | 2021-04-28 | Boehringer Ingelheim Animal Health Usa Inc | Protéines de fusion de fmdv et e2 et leurs utilisations |
| TWI760322B (zh) | 2016-01-29 | 2022-04-11 | 美商百靈佳殷格翰動物保健美國有限公司 | 重組腺病毒載體裝載之fmdv疫苗及其用途 |
| US10172933B2 (en) * | 2016-10-31 | 2019-01-08 | The United States Of America, As Represented By The Secretary Of Agriculture | Mosaic vaccines for serotype a foot-and-mouth disease virus |
| KR102768038B1 (ko) * | 2017-07-12 | 2025-02-18 | 베링거 인겔하임 애니멀 헬스 유에스에이 인크. | 세네카바이러스 a 면역원성 조성물 및 이의 방법 |
| CN108103034B (zh) * | 2017-12-15 | 2022-06-24 | 云南农业大学动物医学院 | 同时表达A型、O型和Asia-1型口蹄疫病毒VP1基因重组腺病毒、构建方法及应用 |
| CN108530522B (zh) * | 2018-03-14 | 2021-09-17 | 中华人民共和国汕头海关 | 一种重组的OmpK多表位多肽、构建方法及其应用 |
| CN110467654B (zh) * | 2018-05-11 | 2022-08-09 | 普莱柯生物工程股份有限公司 | 口蹄疫病毒样颗粒抗原、其制备的疫苗组合物及其制备方法和应用 |
| CN111233984B (zh) * | 2018-11-29 | 2022-08-12 | 普莱柯生物工程股份有限公司 | 一种o型口蹄疫病毒样颗粒抗原、及其疫苗组合物、制备方法和应用 |
| WO2020147015A1 (zh) * | 2019-01-15 | 2020-07-23 | 普莱柯生物工程股份有限公司 | 口蹄疫病毒样颗粒抗原、及其疫苗组合物、制备方法和应用 |
| KR102672787B1 (ko) * | 2019-06-28 | 2024-06-05 | (주)플럼라인생명과학 | 구제역 바이러스 백신 조성물 |
| MX2023004542A (es) * | 2020-10-22 | 2023-05-08 | Intervet Int Bv | Vector de expresion de baculovirus. |
| CN116685687A (zh) * | 2020-10-22 | 2023-09-01 | 英特维特国际股份有限公司 | 杆状病毒表达载体 |
| US12453767B2 (en) * | 2021-08-18 | 2025-10-28 | The United States Of America, As Represented By The Secretary Of Agriculture | Development of mosaic vaccines against foot and mouth disease virus serotype O |
| US20240358816A1 (en) * | 2021-08-20 | 2024-10-31 | Intervet Inc. | Fmdv virus-like particle with stabilizing mutation |
| IL310905A (en) * | 2021-08-20 | 2024-04-01 | Intervet Int Bv | A method for producing a virus-like particle for foot-and-mouth disease virus |
| WO2023020738A1 (en) * | 2021-08-20 | 2023-02-23 | The Pirbright Institute | Fmdv virus-like particle with double stabilizing mutation |
| KR20240046569A (ko) * | 2021-08-20 | 2024-04-09 | 인터벳 인터내셔널 비.브이. | 구제역 바이러스 바이러스-유사 입자의 생성 방법 |
| KR102513632B1 (ko) * | 2021-11-30 | 2023-03-28 | 주식회사 왓슨알앤디 | 구제역 바이러스 유사 입자를 생산하기 위한 백신 플랫폼 |
| US12036318B2 (en) * | 2022-02-16 | 2024-07-16 | Chemical & Schutz High Performance Lubricants, S.A. De C.V. | Self-emulsionable mineral oil as a vehicle in vaccines for poultry |
| JP2025538585A (ja) * | 2022-11-23 | 2025-11-28 | オプティファーム カンパニー リミテッド | 口蹄疫ウィルス様粒子またはナノ粒子生産のための組換え発現ベクターおよびこれを用いたワクチン組成物 |
| CN120265316A (zh) | 2022-11-23 | 2025-07-04 | 致优制药有限公司 | 用于生产口蹄疫病毒样颗粒或纳米颗粒的重组表达载体及利用其的疫苗组合物 |
| CN117210501B (zh) * | 2023-09-13 | 2024-06-07 | 中国农业科学院兰州兽医研究所 | 口蹄疫病毒2b蛋白免疫抑制位点突变的重组口蹄疫病毒株的构建 |
| CN117304277B (zh) * | 2023-09-26 | 2024-03-08 | 中国农业科学院兰州兽医研究所 | 一种o型口蹄疫病毒vp4蛋白t细胞表位多肽及其应用 |
| US20250134984A1 (en) * | 2023-10-26 | 2025-05-01 | The United States Of America, As Represented By The Secretary Of Agriculture | Development of mosaic vaccines against foot and mouth disease virus serotype asia |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA915593B (en) | 1990-07-24 | 1993-03-31 | Novagene Inc | Herpesvirus-based viral vector which expresses a foot and mounth disease virus epitope on the surface of virus-infected cells and on the surface of virus particles,and vaccine against foot and mounth disease containing the same |
| FR2810888B1 (fr) | 2000-06-29 | 2004-07-30 | Merial Sas | Vaccin contre la fievre aphteuse |
| WO2006073431A2 (en) * | 2004-06-25 | 2006-07-13 | Merial Limited | Avipox recombinants expressing foot and mouth disease virus genes |
| WO2007059461A2 (en) | 2005-11-10 | 2007-05-24 | Genvec, Inc. | Adenoviral vector-based foot-and-mouth disease vaccine |
| US20100285056A1 (en) * | 2008-01-09 | 2010-11-11 | Konkuk University Industrial Cooperation Corp. | Baculovirus-Based Vaccines |
| CN101270155B (zh) * | 2008-05-06 | 2011-04-27 | 中国农业科学院兰州兽医研究所 | 通过耐酸性改造在昆虫中组装口蹄疫病毒空衣壳的方法 |
| GB0810710D0 (en) * | 2008-06-11 | 2008-07-16 | Animal Health Inst | Vaccine |
| CN103492410A (zh) * | 2010-03-12 | 2014-01-01 | 梅里亚有限公司 | 蓝舌病毒重组疫苗和其使用 |
| SG194755A1 (en) * | 2011-05-13 | 2013-12-30 | Novartis Ag | Pre-fusion rsv f antigens |
| GB201111183D0 (en) * | 2011-06-30 | 2011-08-17 | Animal Health Inst | Peptide |
| EP2861249A1 (en) * | 2012-06-18 | 2015-04-22 | Novartis AG | Stabilized gp120 |
| US9738689B2 (en) * | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
-
2015
- 2015-09-23 JP JP2017516077A patent/JP6931327B2/ja active Active
- 2015-09-23 CA CA2962225A patent/CA2962225A1/en active Pending
- 2015-09-23 RU RU2017113571A patent/RU2745373C2/ru active
- 2015-09-23 MX MX2017003712A patent/MX388708B/es unknown
- 2015-09-23 AP AP2017009834A patent/AP2017009834A0/en unknown
- 2015-09-23 CN CN201580057248.4A patent/CN107073100B/zh active Active
- 2015-09-23 EP EP15775553.9A patent/EP3197486A1/en active Pending
- 2015-09-23 MA MA40151A patent/MA40151B2/fr unknown
- 2015-09-23 TW TW104131548A patent/TWI733653B/zh active
- 2015-09-23 US US14/863,181 patent/US10010605B2/en active Active
- 2015-09-23 AU AU2015320673A patent/AU2015320673B2/en active Active
- 2015-09-23 KR KR1020177010941A patent/KR102526219B1/ko active Active
- 2015-09-23 AR ARP150103061A patent/AR102006A1/es active IP Right Grant
- 2015-09-23 WO PCT/US2015/051755 patent/WO2016049209A1/en not_active Ceased
- 2015-09-28 JO JOP/2015/0240A patent/JO3600B1/ar active
-
2017
- 2017-03-15 ZA ZA2017/01851A patent/ZA201701851B/en unknown
-
2019
- 2019-07-30 AU AU2019210537A patent/AU2019210537A1/en not_active Abandoned
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