AP2017009834A0 - Fmdv recombinant vaccines and uses thereof - Google Patents

Fmdv recombinant vaccines and uses thereof

Info

Publication number
AP2017009834A0
AP2017009834A0 AP2017009834A AP2017009834A AP2017009834A0 AP 2017009834 A0 AP2017009834 A0 AP 2017009834A0 AP 2017009834 A AP2017009834 A AP 2017009834A AP 2017009834 A AP2017009834 A AP 2017009834A AP 2017009834 A0 AP2017009834 A0 AP 2017009834A0
Authority
AP
ARIPO
Prior art keywords
recombinant vaccines
fmdv recombinant
fmdv
vaccines
recombinant
Prior art date
Application number
AP2017009834A
Other languages
English (en)
Inventor
Jean-Christophe Audonnet
Zahia Hannas-Djebbara
Teshome Mebatsion
Yu Wei Chiang
Justin Widener
Frederic Reynard
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of AP2017009834A0 publication Critical patent/AP2017009834A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/135—Foot- and mouth-disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32123—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AP2017009834A 2014-09-23 2015-09-23 Fmdv recombinant vaccines and uses thereof AP2017009834A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462054073P 2014-09-23 2014-09-23

Publications (1)

Publication Number Publication Date
AP2017009834A0 true AP2017009834A0 (en) 2017-03-31

Family

ID=54256845

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2017009834A AP2017009834A0 (en) 2014-09-23 2015-09-23 Fmdv recombinant vaccines and uses thereof

Country Status (16)

Country Link
US (1) US10010605B2 (cg-RX-API-DMAC7.html)
EP (1) EP3197486A1 (cg-RX-API-DMAC7.html)
JP (1) JP6931327B2 (cg-RX-API-DMAC7.html)
KR (1) KR102526219B1 (cg-RX-API-DMAC7.html)
CN (1) CN107073100B (cg-RX-API-DMAC7.html)
AP (1) AP2017009834A0 (cg-RX-API-DMAC7.html)
AR (1) AR102006A1 (cg-RX-API-DMAC7.html)
AU (2) AU2015320673B2 (cg-RX-API-DMAC7.html)
CA (1) CA2962225A1 (cg-RX-API-DMAC7.html)
JO (1) JO3600B1 (cg-RX-API-DMAC7.html)
MA (1) MA40151B2 (cg-RX-API-DMAC7.html)
MX (1) MX388708B (cg-RX-API-DMAC7.html)
RU (1) RU2745373C2 (cg-RX-API-DMAC7.html)
TW (1) TWI733653B (cg-RX-API-DMAC7.html)
WO (1) WO2016049209A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201701851B (cg-RX-API-DMAC7.html)

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MA43310A (fr) 2015-11-23 2021-04-28 Boehringer Ingelheim Animal Health Usa Inc Protéines de fusion de fmdv et e2 et leurs utilisations
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途
US10172933B2 (en) * 2016-10-31 2019-01-08 The United States Of America, As Represented By The Secretary Of Agriculture Mosaic vaccines for serotype a foot-and-mouth disease virus
KR102768038B1 (ko) * 2017-07-12 2025-02-18 베링거 인겔하임 애니멀 헬스 유에스에이 인크. 세네카바이러스 a 면역원성 조성물 및 이의 방법
CN108103034B (zh) * 2017-12-15 2022-06-24 云南农业大学动物医学院 同时表达A型、O型和Asia-1型口蹄疫病毒VP1基因重组腺病毒、构建方法及应用
CN108530522B (zh) * 2018-03-14 2021-09-17 中华人民共和国汕头海关 一种重组的OmpK多表位多肽、构建方法及其应用
CN110467654B (zh) * 2018-05-11 2022-08-09 普莱柯生物工程股份有限公司 口蹄疫病毒样颗粒抗原、其制备的疫苗组合物及其制备方法和应用
CN111233984B (zh) * 2018-11-29 2022-08-12 普莱柯生物工程股份有限公司 一种o型口蹄疫病毒样颗粒抗原、及其疫苗组合物、制备方法和应用
WO2020147015A1 (zh) * 2019-01-15 2020-07-23 普莱柯生物工程股份有限公司 口蹄疫病毒样颗粒抗原、及其疫苗组合物、制备方法和应用
KR102672787B1 (ko) * 2019-06-28 2024-06-05 (주)플럼라인생명과학 구제역 바이러스 백신 조성물
MX2023004542A (es) * 2020-10-22 2023-05-08 Intervet Int Bv Vector de expresion de baculovirus.
CN116685687A (zh) * 2020-10-22 2023-09-01 英特维特国际股份有限公司 杆状病毒表达载体
US12453767B2 (en) * 2021-08-18 2025-10-28 The United States Of America, As Represented By The Secretary Of Agriculture Development of mosaic vaccines against foot and mouth disease virus serotype O
US20240358816A1 (en) * 2021-08-20 2024-10-31 Intervet Inc. Fmdv virus-like particle with stabilizing mutation
IL310905A (en) * 2021-08-20 2024-04-01 Intervet Int Bv A method for producing a virus-like particle for foot-and-mouth disease virus
WO2023020738A1 (en) * 2021-08-20 2023-02-23 The Pirbright Institute Fmdv virus-like particle with double stabilizing mutation
KR20240046569A (ko) * 2021-08-20 2024-04-09 인터벳 인터내셔널 비.브이. 구제역 바이러스 바이러스-유사 입자의 생성 방법
KR102513632B1 (ko) * 2021-11-30 2023-03-28 주식회사 왓슨알앤디 구제역 바이러스 유사 입자를 생산하기 위한 백신 플랫폼
US12036318B2 (en) * 2022-02-16 2024-07-16 Chemical & Schutz High Performance Lubricants, S.A. De C.V. Self-emulsionable mineral oil as a vehicle in vaccines for poultry
JP2025538585A (ja) * 2022-11-23 2025-11-28 オプティファーム カンパニー リミテッド 口蹄疫ウィルス様粒子またはナノ粒子生産のための組換え発現ベクターおよびこれを用いたワクチン組成物
CN120265316A (zh) 2022-11-23 2025-07-04 致优制药有限公司 用于生产口蹄疫病毒样颗粒或纳米颗粒的重组表达载体及利用其的疫苗组合物
CN117210501B (zh) * 2023-09-13 2024-06-07 中国农业科学院兰州兽医研究所 口蹄疫病毒2b蛋白免疫抑制位点突变的重组口蹄疫病毒株的构建
CN117304277B (zh) * 2023-09-26 2024-03-08 中国农业科学院兰州兽医研究所 一种o型口蹄疫病毒vp4蛋白t细胞表位多肽及其应用
US20250134984A1 (en) * 2023-10-26 2025-05-01 The United States Of America, As Represented By The Secretary Of Agriculture Development of mosaic vaccines against foot and mouth disease virus serotype asia

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Also Published As

Publication number Publication date
CN107073100A (zh) 2017-08-18
AU2015320673B2 (en) 2019-05-02
US20160220659A1 (en) 2016-08-04
BR112017005833A2 (pt) 2018-02-27
AU2019210537A1 (en) 2019-08-15
RU2017113571A3 (cg-RX-API-DMAC7.html) 2019-04-22
AU2015320673A1 (en) 2017-05-11
MA40151A1 (fr) 2018-01-31
MX2017003712A (es) 2017-06-28
CN107073100B (zh) 2021-02-26
US10010605B2 (en) 2018-07-03
JP6931327B2 (ja) 2021-09-01
TWI733653B (zh) 2021-07-21
RU2017113571A (ru) 2018-10-26
BR112017005833A8 (pt) 2023-02-14
JO3600B1 (ar) 2020-07-05
TW201625297A (zh) 2016-07-16
WO2016049209A1 (en) 2016-03-31
AR102006A1 (es) 2017-01-25
CA2962225A1 (en) 2016-03-31
KR102526219B1 (ko) 2023-04-26
EP3197486A1 (en) 2017-08-02
JP2017530124A (ja) 2017-10-12
KR20170058430A (ko) 2017-05-26
RU2745373C2 (ru) 2021-03-24
ZA201701851B (en) 2018-05-30
MA40151B2 (fr) 2022-12-30
MX388708B (es) 2025-03-20

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