JP2017529851A - 養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター - Google Patents

養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター Download PDF

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JP2017529851A
JP2017529851A JP2017516350A JP2017516350A JP2017529851A JP 2017529851 A JP2017529851 A JP 2017529851A JP 2017516350 A JP2017516350 A JP 2017516350A JP 2017516350 A JP2017516350 A JP 2017516350A JP 2017529851 A JP2017529851 A JP 2017529851A
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cell
cells
seq
gpc3
car
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JP2017529851A5 (enExample
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ヘクジー、アンドラス
ゴットシャルク、ステファン、エム．ジー．
メテリツァ、レオニド、エス．
ドッティ、ジャンピエトロ
リー、ウェンポン
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Baylor College of Medicine
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JP2017516350A 2014-09-26 2015-09-25 養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター Pending JP2017529851A (ja)

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US201462055979P 2014-09-26 2014-09-26
US62/055,979 2014-09-26
PCT/US2015/052227 WO2016049459A1 (en) 2014-09-26 2015-09-25 Glypican-3 specific chimeric antigen receptors for adoptive immunotherapy

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JP2017529851A true JP2017529851A (ja) 2017-10-12
JP2017529851A5 JP2017529851A5 (enExample) 2018-11-08

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US (1) US20170281683A1 (enExample)
EP (2) EP3198010B1 (enExample)
JP (1) JP2017529851A (enExample)
DE (1) DE20196219T1 (enExample)
ES (2) ES2851123T1 (enExample)
WO (1) WO2016049459A1 (enExample)

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WO2021186397A1 (en) * 2020-03-18 2021-09-23 Eutilex Co., Ltd. Gpc3 car-t cell compositions and methods of making and using the same
WO2021186395A1 (en) * 2020-03-18 2021-09-23 Eutilex Co., Ltd. Gpc3 car- t cells secreting il-18 and methods of making and using the same
JP2021534740A (ja) * 2018-08-14 2021-12-16 ソティオ，リミティド ライアビリティ カンパニー クレブス回路を調節するトランス代謝分子と組み合わせたキメラ抗原受容体ポリペプチド、及び、それらの治療的使用
JP2023549939A (ja) * 2020-12-14 2023-11-29 北京基因▲啓▼明生物科技有限公司 高い増幅、生存能力及び殺腫瘍作用を有するＣＡＲ－ｉＮＫＴ及びその使用
JP2024045239A (ja) * 2018-12-19 2024-04-02 インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル） キメラ抗原受容体を発現する粘膜関連インバリアントｔ（ｍａｉｔ）細胞

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KR20250072712A (ko) 2016-12-02 2025-05-26 앤젤레스 테라퓨틱스, 인코포레이티드 합성 면역 수용체 및 이의 사용 방법
JP2018093823A (ja) * 2016-12-15 2018-06-21 Ｈｅａｒｔｓｅｅｄ株式会社 未分化幹細胞除去剤及び未分化幹細胞除去方法
TWI780102B (zh) * 2017-01-10 2022-10-11 國立大學法人山口大學 抗gpc3抗體
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EP3441461A1 (en) * 2017-08-11 2019-02-13 Baylor College of Medicine Cd1d-restricted nkt cells as a platform for off-the-shelf cancer immunotherapy
US20220403001A1 (en) 2018-06-12 2022-12-22 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
WO2019246563A1 (en) 2018-06-22 2019-12-26 Kite Pharma, Inc. Chimeric transmembrane proteins and uses thereof
US20210261646A1 (en) * 2018-07-03 2021-08-26 Sotio, LLC Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
WO2020017479A1 (ja) * 2018-07-17 2020-01-23 ノイルイミューン・バイオテック株式会社 抗ｇｐｃ３一本鎖抗体を含むｃａｒ
BR112021006254A2 (pt) 2018-10-01 2021-07-27 Adicet Bio, Inc. composições e métodos relativos a células t¿d engenheiradas e não engenheiradas para tratamento de tumores sólidos
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WO2020097346A1 (en) * 2018-11-07 2020-05-14 Unum Therapeutics Inc. ANTI-GPC3 CHIMERIC ANTIGEN RECEPTORS (CARs) IN COMBINATION WITH TRANS CO-STIMULATORY MOLECULES AND THERAPEUTIC USES THEREOF
EP3894011B1 (en) 2018-12-11 2025-09-17 Obsidian Therapeutics, Inc. Membrane bound il12 compositions and methods for tunable regulation
KR20210149251A (ko) 2019-03-08 2021-12-08 옵시디안 테라퓨틱스, 인크. 조율가능한 조절을 위한 인간 탄산 무수화효소 2 조성물 및 방법
JP7585228B2 (ja) * 2019-04-04 2024-11-18 上海医薬集団股▲フン▼有限公司 腫瘍抗原認識受容体を有する免疫細胞とその応用
JP2022537670A (ja) 2019-06-12 2022-08-29 オブシディアン セラピューティクス， インコーポレイテッド Ｃａ２の組成物および調整可能な制御方法
WO2020252404A1 (en) 2019-06-12 2020-12-17 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
WO2020257823A2 (en) 2019-06-21 2020-12-24 Kite Pharma, Inc. TGF-β RECEPTORS AND METHODS OF USE
WO2021046451A1 (en) 2019-09-06 2021-03-11 Obsidian Therapeutics, Inc. Compositions and methods for dhfr tunable protein regulation
CN116490518A (zh) 2020-07-17 2023-07-25 西穆尔克斯股份有限公司 用于重定向免疫抑制信号传导的嵌合MyD88受体及相关组合物和方法
WO2022133169A1 (en) 2020-12-18 2022-06-23 Century Therapeutics, Inc. Chimeric antigen receptor systems with adaptable receptor specificity
CN117545771A (zh) 2021-04-08 2024-02-09 克莱格医学有限公司 细胞免疫治疗的应用
WO2023091909A1 (en) 2021-11-16 2023-05-25 Sotio Biotech Inc. Treatment of myxoid/round cell liposarcoma patients
CN117230174A (zh) * 2023-04-03 2023-12-15 上海交通大学医学院附属瑞金医院 Gpc3在诊断特发性肺纤维化中的应用

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