JP2017528461A5 - - Google Patents
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- JP2017528461A5 JP2017528461A5 JP2017512983A JP2017512983A JP2017528461A5 JP 2017528461 A5 JP2017528461 A5 JP 2017528461A5 JP 2017512983 A JP2017512983 A JP 2017512983A JP 2017512983 A JP2017512983 A JP 2017512983A JP 2017528461 A5 JP2017528461 A5 JP 2017528461A5
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| US62/146,804 | 2015-04-13 | ||
| PCT/US2015/049225 WO2016040508A1 (en) | 2014-09-10 | 2015-09-09 | Substituted pyrrolidine carboxamide compounds |
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| MX2017002985A (es) | 2014-09-10 | 2017-11-17 | Epizyme Inc | Inhibidores de smyd. |
| CA2960274A1 (en) | 2014-09-10 | 2016-03-17 | Epizyme, Inc. | Isoxazole carboxamide compounds |
| WO2016040502A1 (en) | 2014-09-10 | 2016-03-17 | Epizyme, Inc. | Substituted cyclohexylamine compounds |
| JP2017528464A (ja) | 2014-09-10 | 2017-09-28 | エピザイム，インコーポレイティド | 置換ピペリジン化合物 |
| WO2016040511A1 (en) | 2014-09-10 | 2016-03-17 | Epizyme, Inc. | Isoxazole carboxamides as irreversible smyd inhibitors |
| CN111315735B (zh) | 2017-09-04 | 2024-03-08 | C4医药公司 | 二氢苯并咪唑酮 |
| WO2020181232A1 (en) | 2019-03-06 | 2020-09-10 | C4 Therapeutics, Inc. | Heterocyclic compounds for medical treatment |
| GB201912674D0 (en) * | 2019-09-04 | 2019-10-16 | Mission Therapeutics Ltd | Novel compounds |
Family Cites Families (22)
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| GB1428493A (en) * | 1973-05-02 | 1976-03-17 | Science Union & Cie | Heterocyclic amides processes for their preparation and pharma ceutical compositions containing them |
| JPS52128368A (en) * | 1976-04-15 | 1977-10-27 | Yamanouchi Pharmaceut Co Ltd | Novel carboxylic acid amide derivatives and their preparation |
| GR66581B (enExample) * | 1978-02-21 | 1981-03-27 | Delalande Sa | |
| EP1013276A1 (en) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalkanes as CCR5 modulators |
| DE10148290A1 (de) * | 2001-09-29 | 2003-04-17 | Bayer Cropscience Gmbh | Heterocyclische Amide, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung |
| DE60235114D1 (de) * | 2001-11-01 | 2010-03-04 | Icagen Inc | Pyrazolamide zur anwendung in der behandlung von schmerz |
| JP2006519833A (ja) * | 2003-03-11 | 2006-08-31 | ファイザー・プロダクツ・インク | トランスフォーミング成長因子（ｔｇｆ）阻害剤としてのピラジン化合物 |
| WO2004081011A1 (en) * | 2003-03-14 | 2004-09-23 | Avidex Limited | Immunomodulating heterocyclic compounds |
| TW200526641A (en) * | 2003-12-26 | 2005-08-16 | Daiichi Seiyaku Co | Amidopyrazole derivatives |
| TW200604168A (en) * | 2004-04-02 | 2006-02-01 | Vertex Pharma | Azaindoles useful as inhibitors of rock and other protein kinases |
| WO2006086609A2 (en) * | 2005-02-10 | 2006-08-17 | Axys Pharmaceuticals, Inc. | Inhibitors of tryptase |
| WO2006107923A1 (en) * | 2005-04-05 | 2006-10-12 | Boehringer Ingelheim International Gmbh | Substituted benzylimidazoles useful for the treatment of inflammatory diseases |
| MX2007011198A (es) * | 2005-04-12 | 2007-10-17 | Solvay Pharm Gmbh | Derivados de los 2-(4-sulfonilamino)-3-3hidroxi-3,4-dihidro-2h- croman -6- ilo sustituidos con aminoalquil-amidometilo y medicamentos que contienen estos compuestos. |
| WO2007011760A2 (en) * | 2005-07-15 | 2007-01-25 | Kalypsys, Inc. | Inhibitors of mitotic kinesin |
| DE602007006833D1 (de) * | 2006-10-24 | 2010-07-08 | Janssen Pharmaceutica Nv | Mtp-inhibierende tetrahydronaphthalin-1-carbonsäurederivate |
| EP1975165A1 (de) * | 2007-03-27 | 2008-10-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Substituierte Pyrrolidinamide, deren Herstellung und deren Verwendung als Arzneimittel |
| KR20100020487A (ko) * | 2007-05-24 | 2010-02-22 | 와이어쓰 엘엘씨 | 히스타민-3 길항제로서 아자시클릴벤즈아미드 유도체 |
| EP2178375B1 (en) * | 2007-07-20 | 2014-09-24 | Merck Sharp & Dohme Corp. | Pyrazoloý1,5-a¨pyrimidine derivatives |
| EP2307378A1 (en) * | 2008-06-18 | 2011-04-13 | Pfizer Limited | Nicotinamide derivatives |
| EP2320737B1 (en) * | 2008-08-05 | 2013-07-17 | Merck Sharp & Dohme Corp. | Pyrazolo-[1,5-a]-pyridines as mark inhibitors |
| JP2013028538A (ja) * | 2009-11-13 | 2013-02-07 | Dainippon Sumitomo Pharma Co Ltd | 新規アミド誘導体 |
| KR102196374B1 (ko) * | 2012-11-29 | 2020-12-31 | 케모센트릭스, 인크. | Cxcr7 길항제 |
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- 2015-09-09 AU AU2015315177A patent/AU2015315177A1/en not_active Abandoned
- 2015-09-09 EP EP15839644.0A patent/EP3193609A4/en not_active Withdrawn
- 2015-09-09 US US15/510,583 patent/US20170247326A1/en not_active Abandoned
- 2015-09-09 CA CA2960277A patent/CA2960277A1/en not_active Abandoned
- 2015-09-09 WO PCT/US2015/049225 patent/WO2016040508A1/en not_active Ceased
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2019
- 2019-05-28 US US16/423,618 patent/US20200048195A1/en not_active Abandoned
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