JP2017527602A5 - - Google Patents
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- Publication number
- JP2017527602A5 JP2017527602A5 JP2017515074A JP2017515074A JP2017527602A5 JP 2017527602 A5 JP2017527602 A5 JP 2017527602A5 JP 2017515074 A JP2017515074 A JP 2017515074A JP 2017515074 A JP2017515074 A JP 2017515074A JP 2017527602 A5 JP2017527602 A5 JP 2017527602A5
- Authority
- JP
- Japan
- Prior art keywords
- piperidine
- piperidin
- carboxylic acid
- pyridin
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020035272A JP6908747B2 (ja) | 2014-09-19 | 2020-03-02 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462052537P | 2014-09-19 | 2014-09-19 | |
| US62/052,537 | 2014-09-19 | ||
| PCT/IB2015/057219 WO2016042536A1 (en) | 2014-09-19 | 2015-09-18 | Novel soluble guanylate cyclase activators and their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020035272A Division JP6908747B2 (ja) | 2014-09-19 | 2020-03-02 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017527602A JP2017527602A (ja) | 2017-09-21 |
| JP2017527602A5 true JP2017527602A5 (enExample) | 2018-10-25 |
| JP6678656B2 JP6678656B2 (ja) | 2020-04-08 |
Family
ID=54238488
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017515074A Active JP6678656B2 (ja) | 2014-09-19 | 2015-09-18 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
| JP2020035272A Active JP6908747B2 (ja) | 2014-09-19 | 2020-03-02 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
| JP2021109106A Pending JP2021155450A (ja) | 2014-09-19 | 2021-06-30 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020035272A Active JP6908747B2 (ja) | 2014-09-19 | 2020-03-02 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
| JP2021109106A Pending JP2021155450A (ja) | 2014-09-19 | 2021-06-30 | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9938260B2 (enExample) |
| EP (1) | EP3194384A1 (enExample) |
| JP (3) | JP6678656B2 (enExample) |
| KR (1) | KR20170054508A (enExample) |
| CN (1) | CN106687456B (enExample) |
| AU (1) | AU2015319724B2 (enExample) |
| BR (1) | BR112017005660A2 (enExample) |
| CA (1) | CA2961745A1 (enExample) |
| CL (1) | CL2017000640A1 (enExample) |
| CO (1) | CO2017002506A2 (enExample) |
| CR (1) | CR20170102A (enExample) |
| DO (1) | DOP2017000073A (enExample) |
| EA (1) | EA033697B1 (enExample) |
| IL (1) | IL251094A0 (enExample) |
| MA (1) | MA40583A (enExample) |
| MX (1) | MX2017003621A (enExample) |
| PE (1) | PE20170937A1 (enExample) |
| PH (1) | PH12017500481A1 (enExample) |
| SG (1) | SG11201701915TA (enExample) |
| WO (1) | WO2016042536A1 (enExample) |
| ZA (1) | ZA201701835B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2685230C2 (ru) | 2014-02-06 | 2019-04-17 | Хептарес Терапьютикс Лимитед | Бициклические азотсодержащие соединения как агонисты М1 мускариновых рецепторов |
| EA033697B1 (ru) * | 2014-09-19 | 2019-11-18 | Glaxosmithkline Ip Dev Ltd | Активаторы растворимой гуанилатциклазы и их применение |
| WO2016042084A1 (en) | 2014-09-19 | 2016-03-24 | Bayer Pharma Aktiengesellschaft | Benzyl substituted indazoles as bub1 inhibitors |
| US11331308B2 (en) | 2016-10-11 | 2022-05-17 | Bayer Pharma Aktiengesellschaft | Combination containing sGC activators and mineralocorticoid receptor antagonists |
| WO2019081456A1 (en) | 2017-10-24 | 2019-05-02 | Bayer Aktiengesellschaft | USE OF SGC ACTIVATORS AND STIMULATORS COMPRISING A BETA2 SUBUNIT |
| EP3498298A1 (en) | 2017-12-15 | 2019-06-19 | Bayer AG | The use of sgc stimulators and sgc activators alone or in combination with pde5 inhibitors for the treatment of bone disorders including osteogenesis imperfecta (oi) |
| CN112055584A (zh) | 2018-04-30 | 2020-12-08 | 拜耳公司 | sGC活化剂和sGC刺激剂用于治疗认知障碍的用途 |
| MA52616A (fr) | 2018-05-15 | 2021-03-24 | Bayer Ag | Benzamides à substitution 1,3-thiazol-2-yl pour le traitement de maladies associées à la sensibilisation de fibres nerveuses |
| US11508483B2 (en) | 2018-05-30 | 2022-11-22 | Adverio Pharma Gmbh | Method of identifying a subgroup of patients suffering from dcSSc which benefits from a treatment with sGC stimulators and sGC activators in a higher degree than a control group |
| WO2020148379A1 (en) | 2019-01-17 | 2020-07-23 | Bayer Aktiengesellschaft | Methods to determine whether a subject is suitable of being treated with an agonist of soluble guanylyl cyclase (sgc) |
| CN119300815A (zh) | 2022-06-09 | 2025-01-10 | 拜耳公司 | 用于治疗女性射血分数保留型心力衰竭的可溶性鸟苷酸环化酶激活剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5602143A (en) | 1994-12-08 | 1997-02-11 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of guanylate cyclase inhibitors |
| JP5411703B2 (ja) * | 2006-11-09 | 2014-02-12 | アルコン リサーチ， リミテッド | 薬物送達のための水不溶性ポリマーマトリクス |
| PE20091258A1 (es) * | 2007-12-03 | 2009-09-12 | Smithkline Beecham Corp | Derivados de piridina como activadores de la guanilato ciclasa soluble |
| WO2010015653A1 (en) * | 2008-08-07 | 2010-02-11 | Smithkline Beecham Corporation | Pyrimidine derivatives as activators of soluble guanylate cyclase |
| CA2753434C (en) | 2009-02-26 | 2014-07-15 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| DE102009012314A1 (de) | 2009-03-09 | 2010-09-16 | Bayer Schering Pharma Aktiengesellschaft | Oxo-heterocyclisch substituierte Alkylcarbonsäuren und ihre Verwendung |
| JP5636296B2 (ja) | 2011-01-20 | 2014-12-03 | 公益財団法人微生物化学研究会 | 塩分含有有機廃液処理剤、並びに、塩分濃度低下剤、塩分含有有機廃液の処理方法、及び包括固定担体 |
| EA033697B1 (ru) * | 2014-09-19 | 2019-11-18 | Glaxosmithkline Ip Dev Ltd | Активаторы растворимой гуанилатциклазы и их применение |
-
2015
- 2015-09-18 EA EA201790655A patent/EA033697B1/ru not_active IP Right Cessation
- 2015-09-18 KR KR1020177010181A patent/KR20170054508A/ko not_active Ceased
- 2015-09-18 CN CN201580050717.XA patent/CN106687456B/zh active Active
- 2015-09-18 BR BR112017005660A patent/BR112017005660A2/pt not_active Application Discontinuation
- 2015-09-18 AU AU2015319724A patent/AU2015319724B2/en active Active
- 2015-09-18 JP JP2017515074A patent/JP6678656B2/ja active Active
- 2015-09-18 CR CR20170102A patent/CR20170102A/es unknown
- 2015-09-18 MA MA040583A patent/MA40583A/fr unknown
- 2015-09-18 MX MX2017003621A patent/MX2017003621A/es unknown
- 2015-09-18 US US15/509,895 patent/US9938260B2/en active Active
- 2015-09-18 SG SG11201701915TA patent/SG11201701915TA/en unknown
- 2015-09-18 CA CA2961745A patent/CA2961745A1/en not_active Abandoned
- 2015-09-18 WO PCT/IB2015/057219 patent/WO2016042536A1/en not_active Ceased
- 2015-09-18 PE PE2017000478A patent/PE20170937A1/es unknown
- 2015-09-18 EP EP15772026.9A patent/EP3194384A1/en not_active Withdrawn
-
2017
- 2017-03-12 IL IL251094A patent/IL251094A0/en unknown
- 2017-03-14 PH PH12017500481A patent/PH12017500481A1/en unknown
- 2017-03-14 ZA ZA2017/01835A patent/ZA201701835B/en unknown
- 2017-03-16 CO CONC2017/0002506A patent/CO2017002506A2/es unknown
- 2017-03-16 CL CL2017000640A patent/CL2017000640A1/es unknown
- 2017-03-16 DO DO2017000073A patent/DOP2017000073A/es unknown
-
2018
- 2018-03-05 US US15/911,797 patent/US10472350B2/en active Active
-
2020
- 2020-03-02 JP JP2020035272A patent/JP6908747B2/ja active Active
-
2021
- 2021-06-30 JP JP2021109106A patent/JP2021155450A/ja active Pending
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