JP2011530607A5 - - Google Patents
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- Publication number
- JP2011530607A5 JP2011530607A5 JP2011523078A JP2011523078A JP2011530607A5 JP 2011530607 A5 JP2011530607 A5 JP 2011530607A5 JP 2011523078 A JP2011523078 A JP 2011523078A JP 2011523078 A JP2011523078 A JP 2011523078A JP 2011530607 A5 JP2011530607 A5 JP 2011530607A5
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- phenyl
- substituted
- amino
- pyrimidylaminobenzamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8838208P | 2008-08-13 | 2008-08-13 | |
| US61/088,382 | 2008-08-13 | ||
| US16450109P | 2009-03-30 | 2009-03-30 | |
| US61/164,501 | 2009-03-30 | ||
| PCT/US2009/053358 WO2010019540A1 (en) | 2008-08-13 | 2009-08-11 | Treatment of pulmonary arterial hypertension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011530607A JP2011530607A (ja) | 2011-12-22 |
| JP2011530607A5 true JP2011530607A5 (enExample) | 2012-09-27 |
Family
ID=41137217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523078A Pending JP2011530607A (ja) | 2008-08-13 | 2009-08-11 | 肺動脈高血圧の治療 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20110190313A1 (enExample) |
| EP (1) | EP2315592A1 (enExample) |
| JP (1) | JP2011530607A (enExample) |
| KR (1) | KR20110053354A (enExample) |
| CN (1) | CN102123711A (enExample) |
| AU (1) | AU2009282104A1 (enExample) |
| BR (1) | BRPI0917491A2 (enExample) |
| CA (1) | CA2732789A1 (enExample) |
| CL (1) | CL2011000295A1 (enExample) |
| IL (1) | IL210922A0 (enExample) |
| MA (1) | MA32617B1 (enExample) |
| MX (1) | MX2011001668A (enExample) |
| NZ (1) | NZ590839A (enExample) |
| RU (1) | RU2011109078A (enExample) |
| TW (1) | TW201010999A (enExample) |
| WO (1) | WO2010019540A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3130908A1 (en) | 2009-06-30 | 2010-12-30 | Mallinckrodt Hospital Products IP Limited | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
| EP3007689B1 (en) | 2013-01-10 | 2018-03-07 | Pulmokine, Inc. | Non-selective kinase inhibitors |
| CA2919498C (en) * | 2013-07-31 | 2023-07-25 | Windward Pharma, Inc. | Aerosol nintedanib compounds and uses thereof |
| EP3054937B1 (en) | 2013-10-11 | 2023-07-26 | Pulmokine, Inc. | Spray dry formulations |
| KR20230093341A (ko) | 2016-10-27 | 2023-06-27 | 풀모킨 인코포레이티드 | 폐고혈압을 치료하기 위한 병용 요법 |
| MX2019005401A (es) | 2016-11-08 | 2019-08-05 | Reata Pharmaceuticals Inc | Metodos para tratar el sindrome de alport con bardoxolona metilo o analogos de la misma. |
| WO2019157337A1 (en) * | 2018-02-08 | 2019-08-15 | Pulmokine, Inc. | Formulations of kinase inhibitors and prostanoids |
| US11464776B2 (en) | 2019-05-16 | 2022-10-11 | Aerovate Therapeutics, Inc. | Inhalable imatinib formulations, manufacture, and uses thereof |
| US20200360277A1 (en) | 2019-05-16 | 2020-11-19 | Aerovate Therapeutics, Inc. | Inhalable formulations of imatinib, imatinib metabolites, imatinib salts, their manufacture, and uses thereof |
| US20210154193A1 (en) * | 2019-11-25 | 2021-05-27 | PHPrecisionMed, LLC | Pharmaceutical compositions for the treatment of pulmonary hypertension |
| CN115315421B (zh) | 2019-12-13 | 2024-12-03 | 日本新药株式会社 | 作为pdgf受体激酶抑制剂的化合物和组合物 |
| JP2023542298A (ja) * | 2020-09-11 | 2023-10-06 | プルモシム セラピューティクス リミテッド ライアビリティ カンパニー | 肺高血圧症を治療又は予防する組成物及び方法 |
| US20220152025A1 (en) | 2020-11-17 | 2022-05-19 | United Therapeutics Corporation | Inhaled imatinib for pulmonary hypertension |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| GB0215676D0 (en) * | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| JP4942297B2 (ja) * | 2002-10-25 | 2012-05-30 | ジ アドミニストレイターズ オブ ザ チューレン エデュケイショナル ファンド | 肺高血圧症の処置を目的としたｎ−｛５−［４−（４−メチルピペラジノメチル）−ベンゾイルアミド］−２−メチルフェニル｝−４−（３−ピリジル）−２−ピリジン−アミンの使用 |
| GB0325031D0 (en) * | 2003-10-27 | 2003-12-03 | Novartis Ag | Organic compounds |
| CN101203224B (zh) * | 2005-01-28 | 2010-11-03 | 诺瓦提斯公司 | 嘧啶基氨基苯甲酰胺在制备治疗对Tie-2激酶活性的调节有响应的疾病的药物中的用途 |
| RU2415672C2 (ru) * | 2005-05-02 | 2011-04-10 | Новартис Аг | Производные пиримидиламинобензамида для лечения синдрома гиперэозинофилии |
| ES2391199T3 (es) * | 2005-12-06 | 2012-11-22 | Novartis Ag | Derivados de pirimidilaminobenzamida para el tratamiento de neurofibromatosis |
| CA2668190A1 (en) * | 2006-11-03 | 2008-05-15 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
-
2009
- 2009-08-11 RU RU2011109078/04A patent/RU2011109078A/ru not_active Application Discontinuation
- 2009-08-11 CN CN2009801314677A patent/CN102123711A/zh active Pending
- 2009-08-11 AU AU2009282104A patent/AU2009282104A1/en not_active Abandoned
- 2009-08-11 WO PCT/US2009/053358 patent/WO2010019540A1/en not_active Ceased
- 2009-08-11 CA CA2732789A patent/CA2732789A1/en not_active Abandoned
- 2009-08-11 EP EP09791358A patent/EP2315592A1/en not_active Withdrawn
- 2009-08-11 KR KR1020117005744A patent/KR20110053354A/ko not_active Withdrawn
- 2009-08-11 US US13/058,742 patent/US20110190313A1/en not_active Abandoned
- 2009-08-11 NZ NZ590839A patent/NZ590839A/xx not_active IP Right Cessation
- 2009-08-11 MX MX2011001668A patent/MX2011001668A/es not_active Application Discontinuation
- 2009-08-11 JP JP2011523078A patent/JP2011530607A/ja active Pending
- 2009-08-11 BR BRPI0917491A patent/BRPI0917491A2/pt not_active IP Right Cessation
- 2009-08-12 TW TW098127172A patent/TW201010999A/zh unknown
-
2011
- 2011-01-27 IL IL210922A patent/IL210922A0/en unknown
- 2011-02-11 CL CL2011000295A patent/CL2011000295A1/es unknown
- 2011-03-07 MA MA33678A patent/MA32617B1/fr unknown
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