JP2017525702A5 - - Google Patents
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- JP2017525702A5 JP2017525702A5 JP2017509000A JP2017509000A JP2017525702A5 JP 2017525702 A5 JP2017525702 A5 JP 2017525702A5 JP 2017509000 A JP2017509000 A JP 2017509000A JP 2017509000 A JP2017509000 A JP 2017509000A JP 2017525702 A5 JP2017525702 A5 JP 2017525702A5
- Authority
- JP
- Japan
- Prior art keywords
- pgrg1
- composition
- formulation
- isolated
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000203 mixture Substances 0.000 claims description 89
- 238000009472 formulation Methods 0.000 claims description 21
- 241000045403 Astragalus propinquus Species 0.000 claims description 18
- 241000124008 Mammalia Species 0.000 claims description 15
- 235000006533 astragalus Nutrition 0.000 claims description 12
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 11
- 210000004369 blood Anatomy 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 6
- 229940109239 creatinine Drugs 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 6
- 230000011132 hemopoiesis Effects 0.000 claims description 6
- 229940124597 therapeutic agent Drugs 0.000 claims description 6
- AEMOLEFTQBMNLQ-YMDCURPLSA-N D-galactopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-YMDCURPLSA-N 0.000 claims description 4
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 claims description 4
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 claims description 4
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 4
- 230000004064 dysfunction Effects 0.000 claims description 4
- 210000000987 immune system Anatomy 0.000 claims description 4
- 230000001939 inductive effect Effects 0.000 claims description 4
- 208000017169 kidney disease Diseases 0.000 claims description 4
- 235000015872 dietary supplement Nutrition 0.000 claims description 3
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims description 2
- AEMOLEFTQBMNLQ-UHFFFAOYSA-N beta-D-galactopyranuronic acid Natural products OC1OC(C(O)=O)C(O)C(O)C1O AEMOLEFTQBMNLQ-UHFFFAOYSA-N 0.000 claims description 2
- 230000036737 immune function Effects 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 239000012465 retentate Substances 0.000 claims description 2
- 241000894007 species Species 0.000 claims description 2
- 238000000108 ultra-filtration Methods 0.000 claims description 2
- 238000004820 blood count Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462038583P | 2014-08-18 | 2014-08-18 | |
| US62/038,583 | 2014-08-18 | ||
| PCT/US2015/045574 WO2016028714A1 (en) | 2014-08-18 | 2015-08-17 | Polygalacturonan rhamnogalacturonan1 (pgrg1) composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017525702A JP2017525702A (ja) | 2017-09-07 |
| JP2017525702A5 true JP2017525702A5 (enExample) | 2018-08-02 |
Family
ID=55351173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017509000A Pending JP2017525702A (ja) | 2014-08-18 | 2015-08-17 | ポリガラクツロナンラムノガラクツロナン（ｐｇｒｇ１）組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170232035A1 (enExample) |
| EP (1) | EP3191110A4 (enExample) |
| JP (1) | JP2017525702A (enExample) |
| CN (1) | CN106794211A (enExample) |
| WO (1) | WO2016028714A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105866318A (zh) * | 2016-03-16 | 2016-08-17 | 保定冀中药业有限公司 | 一种麻杏石甘口服液中麻黄的薄层色谱检测方法 |
| CN108084290A (zh) * | 2018-01-09 | 2018-05-29 | 东北农业大学 | 一种微波辅助提取薇菜中多糖的方法 |
| CN110128562B (zh) * | 2019-05-29 | 2021-05-25 | 黄河科技学院 | 一种抗肿瘤补骨脂多糖及其提取分离方法和在制备抗肿瘤药物方面的应用 |
| CN111999425A (zh) * | 2020-08-21 | 2020-11-27 | 广东容大生物股份有限公司 | 一种银黄甘颗粒中甘草成分的定性鉴别方法 |
| CN112961258B (zh) * | 2021-02-26 | 2023-02-07 | 重庆医科大学附属第二医院 | 一种红参均一性多糖及其提取方法与应用 |
| CN115078581B (zh) * | 2022-06-21 | 2024-08-27 | 上海长征医院 | 基于uhplc-q-tof/ms识别柴胡桂枝干姜免煎剂成分的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6203600A (en) * | 1999-06-30 | 2001-01-31 | Pharmagenesis, Inc. | Hematopoietic arabinogalactan composition |
| EP1294750A2 (en) * | 2000-06-29 | 2003-03-26 | Pharmagenesis, Inc. | Acid-modified arabinogalactan protein composition |
| JP2004107295A (ja) * | 2002-09-20 | 2004-04-08 | National Agriculture & Bio-Oriented Research Organization | ヒスタミン遊離抑制剤 |
| CA2582428A1 (en) * | 2004-03-26 | 2005-10-13 | Glycogenesys, Inc. | Modified pectins, compositions and methods related thereto |
| EP2376096B1 (en) * | 2008-12-15 | 2019-07-24 | Phytohealth Corporation | Treating idiopathic thrombocytopenic purpura with compositions comprising extracts of astragalus membranaceus |
| CN102762597A (zh) * | 2009-12-11 | 2012-10-31 | 联合利华公众股份有限公司 | 适合调节免疫应答的多糖 |
| ES2689261T3 (es) * | 2011-04-29 | 2018-11-12 | Nutrileads B.V. | Método para el aislamiento de polisacáridos |
| JP6185473B2 (ja) * | 2011-09-16 | 2017-08-23 | ガレクティン・セラピューティクス・インコーポレイテッドＧａｌｅｃｔｉｎ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 非アルコール性脂肪性肝炎および非アルコール性脂肪肝疾患を処置するためのガラクト−ラムノガラクツロネート組成物 |
| TWI554277B (zh) * | 2012-03-28 | 2016-10-21 | 泰宗生物科技股份有限公司 | 預防及治療非酒精性脂肪肝之醫藥組成物 |
| ES2848538T3 (es) * | 2012-06-06 | 2021-08-10 | Galectin Therapeutics Inc | Composiciones de galacto-ramnogalacturonato para el tratamiento de enfermedades asociadas con elevada óxido nítrico sintasa inducible |
-
2015
- 2015-08-17 JP JP2017509000A patent/JP2017525702A/ja active Pending
- 2015-08-17 US US15/502,971 patent/US20170232035A1/en not_active Abandoned
- 2015-08-17 CN CN201580048061.8A patent/CN106794211A/zh active Pending
- 2015-08-17 EP EP15834396.2A patent/EP3191110A4/en not_active Withdrawn
- 2015-08-17 WO PCT/US2015/045574 patent/WO2016028714A1/en not_active Ceased
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