JP2017525702A - ポリガラクツロナンラムノガラクツロナン（ｐｇｒｇ１）組成物 - Google Patents

ポリガラクツロナンラムノガラクツロナン（ｐｇｒｇ１）組成物 Download PDF

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Publication number
JP2017525702A
JP2017525702A JP2017509000A JP2017509000A JP2017525702A JP 2017525702 A JP2017525702 A JP 2017525702A JP 2017509000 A JP2017509000 A JP 2017509000A JP 2017509000 A JP2017509000 A JP 2017509000A JP 2017525702 A JP2017525702 A JP 2017525702A
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Japan
Prior art keywords
pgrg1
composition
composition according
isolated
astragalus
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JP2017509000A
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Japanese (ja)
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JP2017525702A5 (enExample
Inventor
ジョン エイチ． ムッサー，
ジョン エイチ． ムッサー，
ジェンファ アン，
ジェンファ アン，
Original Assignee
ファーマジェネシス， インコーポレイテッド
ファーマジェネシス， インコーポレイテッド
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Publication of JP2017525702A publication Critical patent/JP2017525702A/ja
Publication of JP2017525702A5 publication Critical patent/JP2017525702A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/732—Pectin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof
    • C08B37/0048—Processes of extraction from organic materials
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017509000A 2014-08-18 2015-08-17 ポリガラクツロナンラムノガラクツロナン（ｐｇｒｇ１）組成物 Pending JP2017525702A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462038583P 2014-08-18 2014-08-18
US62/038,583 2014-08-18
PCT/US2015/045574 WO2016028714A1 (en) 2014-08-18 2015-08-17 Polygalacturonan rhamnogalacturonan1 (pgrg1) composition

Publications (2)

Publication Number Publication Date
JP2017525702A true JP2017525702A (ja) 2017-09-07
JP2017525702A5 JP2017525702A5 (enExample) 2018-08-02

Family

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Family Applications (1)

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JP2017509000A Pending JP2017525702A (ja) 2014-08-18 2015-08-17 ポリガラクツロナンラムノガラクツロナン（ｐｇｒｇ１）組成物

Country Status (5)

Country Link
US (1) US20170232035A1 (enExample)
EP (1) EP3191110A4 (enExample)
JP (1) JP2017525702A (enExample)
CN (1) CN106794211A (enExample)
WO (1) WO2016028714A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105866318A (zh) * 2016-03-16 2016-08-17 保定冀中药业有限公司 一种麻杏石甘口服液中麻黄的薄层色谱检测方法
CN108084290A (zh) * 2018-01-09 2018-05-29 东北农业大学 一种微波辅助提取薇菜中多糖的方法
CN110128562B (zh) * 2019-05-29 2021-05-25 黄河科技学院 一种抗肿瘤补骨脂多糖及其提取分离方法和在制备抗肿瘤药物方面的应用
CN111999425A (zh) * 2020-08-21 2020-11-27 广东容大生物股份有限公司 一种银黄甘颗粒中甘草成分的定性鉴别方法
CN112961258B (zh) * 2021-02-26 2023-02-07 重庆医科大学附属第二医院 一种红参均一性多糖及其提取方法与应用
CN115078581B (zh) * 2022-06-21 2024-08-27 上海长征医院 基于uhplc-q-tof/ms识别柴胡桂枝干姜免煎剂成分的方法
CN118459617B (zh) * 2024-04-28 2026-08-07 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） 一种延缓生殖衰老的复方多糖组合物的制备方法和应用
FR3164898A1 (fr) * 2024-07-25 2026-01-30 Larena Préparation d’une plante du genre Astragalus

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004502703A (ja) * 2000-06-29 2004-01-29 ファーマジェネシス，　インコーポレイテッド 酸修飾アラビノガラクタンタンパク質組成物
JP2004107295A (ja) * 2002-09-20 2004-04-08 National Agriculture & Bio-Oriented Research Organization ヒスタミン遊離抑制剤
JP2012512176A (ja) * 2008-12-15 2012-05-31 エコファーム、エルエルシー キバナオウギ抽出物を含む組成物による特発性血小板減少性紫斑病の治療
JP2013203739A (ja) * 2012-03-28 2013-10-07 Tcm Biotech Internatl Corp 肝線維化又は非アルコール性脂肪性肝を予防、治療する医薬組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1200482A1 (en) * 1999-06-30 2002-05-02 Pharmagenesis, Inc. Hematopoietic arabinogalactan composition
EP1765874A1 (en) * 2004-03-26 2007-03-28 Glycogenesys, Inc. Modified pectins, compositions and methods related thereto
EP2510014A1 (en) * 2009-12-11 2012-10-17 Unilever NV Polysaccharide suitable to modulate immune response
ES2689261T3 (es) * 2011-04-29 2018-11-12 Nutrileads B.V. Método para el aislamiento de polisacáridos
CA2848711C (en) * 2011-09-16 2019-08-06 Galectin Therapeutics, Inc. Galacto-rhamnogalacturonate compositions for the treatment of non-alcoholic steatohepatitis and non-alcoholic fatty liver disease
WO2013184892A1 (en) * 2012-06-06 2013-12-12 Galectin Therapeutics, Inc. Galacto-rhamnogalacturonate compositions for the treatment of diseases associated with elevated inducible nitric oxide synthase

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
JP2004502703A (ja) * 2000-06-29 2004-01-29 ファーマジェネシス，　インコーポレイテッド 酸修飾アラビノガラクタンタンパク質組成物
JP2004107295A (ja) * 2002-09-20 2004-04-08 National Agriculture & Bio-Oriented Research Organization ヒスタミン遊離抑制剤
JP2012512176A (ja) * 2008-12-15 2012-05-31 エコファーム、エルエルシー キバナオウギ抽出物を含む組成物による特発性血小板減少性紫斑病の治療
JP2013203739A (ja) * 2012-03-28 2013-10-07 Tcm Biotech Internatl Corp 肝線維化又は非アルコール性脂肪性肝を予防、治療する医薬組成物

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Publication number Publication date
EP3191110A1 (en) 2017-07-19
EP3191110A4 (en) 2018-04-18
WO2016028714A1 (en) 2016-02-25
US20170232035A1 (en) 2017-08-17
CN106794211A (zh) 2017-05-31

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