JP2017524712A5 - - Google Patents
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- Publication number
- JP2017524712A5 JP2017524712A5 JP2017507390A JP2017507390A JP2017524712A5 JP 2017524712 A5 JP2017524712 A5 JP 2017524712A5 JP 2017507390 A JP2017507390 A JP 2017507390A JP 2017507390 A JP2017507390 A JP 2017507390A JP 2017524712 A5 JP2017524712 A5 JP 2017524712A5
- Authority
- JP
- Japan
- Prior art keywords
- injection
- composition
- particle
- glucocorticoid
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462037000P | 2014-08-13 | 2014-08-13 | |
| US62/037,000 | 2014-08-13 | ||
| US201562139561P | 2015-03-27 | 2015-03-27 | |
| US62/139,561 | 2015-03-27 | ||
| PCT/US2015/043478 WO2016025215A1 (en) | 2014-08-13 | 2015-08-03 | Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017524712A JP2017524712A (ja) | 2017-08-31 |
| JP2017524712A5 true JP2017524712A5 (enExample) | 2018-08-16 |
Family
ID=54011072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507390A Pending JP2017524712A (ja) | 2014-08-13 | 2015-08-03 | 角膜同種移植片拒絶および新血管形成を予防するためのグルココルチコイドを負荷したナノ粒子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10195212B2 (enExample) |
| EP (1) | EP3193827A1 (enExample) |
| JP (1) | JP2017524712A (enExample) |
| KR (1) | KR20170046146A (enExample) |
| CN (1) | CN106794152A (enExample) |
| CA (1) | CA2957764C (enExample) |
| MX (1) | MX2017001863A (enExample) |
| WO (1) | WO2016025215A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011106702A2 (en) | 2010-02-25 | 2011-09-01 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| JP6847848B2 (ja) | 2014-12-15 | 2021-03-24 | ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ | スニチニブ製剤、及び緑内障の治療におけるその使用方法 |
| EP3233098B1 (en) | 2014-12-15 | 2024-05-29 | The Johns Hopkins University | Cvs transplantation for treatment of bacterial vaginosis |
| KR20240126072A (ko) | 2015-01-27 | 2024-08-20 | 더 존스 홉킨스 유니버시티 | 점막표면에서 활성제의 향상된 수송을 위한 저장성 하이드로겔 제제 |
| KR20180058758A (ko) | 2015-09-22 | 2018-06-01 | 그레이버그 비젼, 인크. | 안구 장애의 치료를 위한 화합물 및 조성물 |
| HK1257499A1 (zh) | 2015-11-12 | 2019-10-25 | Graybug Vision, Inc. | 用於治疗的聚集性微粒 |
| DE102017002454A1 (de) * | 2017-03-14 | 2018-09-20 | Friedrich-Schiller-Universität Jena | Organische Polymerpartikel enthaltend Poly(oxazolin)-Stabilisatoren und Verwendung von Poly(oxazolinen) zur Stabilisierung von organischen Polymerpartikeln |
| EP3600324A4 (en) | 2017-03-23 | 2020-12-09 | Graybug Vision, Inc. | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS |
| AU2018265415A1 (en) | 2017-05-10 | 2019-10-31 | Graybug Vision, Inc. | Extended release microparticles and suspensions thereof for medical therapy |
| WO2019071275A1 (en) * | 2017-10-06 | 2019-04-11 | Aciont Inc. | DEVICES FOR DELIVERY OF NON-INVASIVE OCULAR MEDICINE |
| US12496279B2 (en) * | 2019-04-11 | 2025-12-16 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
| US20230081539A1 (en) * | 2020-02-21 | 2023-03-16 | The Johns Hopkins University | Suprachoroidal delivery of drug particles to reduce toxicity |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4432964A (en) * | 1981-08-24 | 1984-02-21 | Alza Corporation | Topical composition containing steroid in two forms released independently from polymeric carrier |
| US4888176A (en) | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
| US4757128A (en) | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
| US4789724A (en) | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
| US4857311A (en) | 1987-07-31 | 1989-08-15 | Massachusetts Institute Of Technology | Polyanhydrides with improved hydrolytic degradation properties |
| US4997652A (en) | 1987-12-22 | 1991-03-05 | Visionex | Biodegradable ocular implants |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| WO2004084871A1 (en) * | 2003-03-26 | 2004-10-07 | Ltt Bio-Pharma Co., Ltd. | Intravenous nanoparticles for targenting drug delivery and sustained drug release |
| US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
| US20050226814A1 (en) | 2004-04-13 | 2005-10-13 | Bausch & Lomb Incorporated | Diagnostic method and kit for implantation of a sustained release drug-delivery implant with a steroid |
| US8246949B2 (en) * | 2004-10-27 | 2012-08-21 | Aciont, Inc. | Methods and devices for sustained in-vivo release of an active agent |
| JP2007001926A (ja) * | 2005-06-24 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 吸入・噴霧用ステロイド製剤 |
| WO2007074604A1 (ja) * | 2005-12-26 | 2007-07-05 | Ltt Bio-Pharma Co., Ltd. | 水溶性非ペプチド性低分子薬物含有ナノ粒子 |
| WO2008139804A1 (ja) * | 2007-05-14 | 2008-11-20 | Ltt Bio-Pharma Co., Ltd. | 徐放性の陰荷電基を持つ低分子薬物含有ナノ粒子 |
| CN101970042A (zh) * | 2008-02-25 | 2011-02-09 | 眼门药品公司 | 经由离子电渗法增强递送治疗药物至眼部组织 |
| US20110206773A1 (en) * | 2008-05-20 | 2011-08-25 | Yale University | Sustained delivery of drugs from biodegradable polymeric microparticles |
| US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
| US20120177741A1 (en) | 2009-09-29 | 2012-07-12 | Eyegate Pharmaceuticals, Inc. | Positively-charged poly (d,l-lactide-co-glycolide) nanoparticles and fabrication methods of the same |
| EP2755659A2 (en) | 2011-09-13 | 2014-07-23 | Altacor Limited | Pharmaceutical nanoparticle compositions |
| EP2804632B1 (en) | 2012-01-19 | 2019-09-18 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
| CN111700879A (zh) * | 2012-05-03 | 2020-09-25 | 卡拉制药公司 | 显示提高的粘膜转移的药物纳米粒子 |
-
2015
- 2015-08-03 CA CA2957764A patent/CA2957764C/en active Active
- 2015-08-03 JP JP2017507390A patent/JP2017524712A/ja active Pending
- 2015-08-03 MX MX2017001863A patent/MX2017001863A/es unknown
- 2015-08-03 US US15/502,732 patent/US10195212B2/en active Active
- 2015-08-03 CN CN201580053822.9A patent/CN106794152A/zh active Pending
- 2015-08-03 WO PCT/US2015/043478 patent/WO2016025215A1/en not_active Ceased
- 2015-08-03 EP EP15756267.9A patent/EP3193827A1/en not_active Withdrawn
- 2015-08-03 KR KR1020177006811A patent/KR20170046146A/ko not_active Withdrawn
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