CA2957764C - Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization - Google Patents
Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization Download PDFInfo
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- CA2957764C CA2957764C CA2957764A CA2957764A CA2957764C CA 2957764 C CA2957764 C CA 2957764C CA 2957764 A CA2957764 A CA 2957764A CA 2957764 A CA2957764 A CA 2957764A CA 2957764 C CA2957764 C CA 2957764C
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Landscapes
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- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Steroid Compounds (AREA)
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| US201562139561P | 2015-03-27 | 2015-03-27 | |
| US62/139,561 | 2015-03-27 | ||
| PCT/US2015/043478 WO2016025215A1 (en) | 2014-08-13 | 2015-08-03 | Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization |
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| US8889193B2 (en) | 2010-02-25 | 2014-11-18 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| EP3233098B1 (en) | 2014-12-15 | 2024-05-29 | The Johns Hopkins University | Cvs transplantation for treatment of bacterial vaginosis |
| CN107278151A (zh) | 2014-12-15 | 2017-10-20 | 约翰霍普金斯大学 | 舒尼替尼制剂及其在治疗青光眼中的使用方法 |
| CN107635545A (zh) | 2015-01-27 | 2018-01-26 | 约翰霍普金斯大学 | 用于增强粘膜表面处活性剂的输送的低渗水凝胶制剂 |
| KR20180058758A (ko) | 2015-09-22 | 2018-06-01 | 그레이버그 비젼, 인크. | 안구 장애의 치료를 위한 화합물 및 조성물 |
| BR112018009644A2 (pt) | 2015-11-12 | 2018-11-06 | Graybug Vision Inc | micropartículas agregantes sólidas modificadas na superfície, material injetável, processo para preparação de micropartículas agregantes sólidas modificadas na superfície, método para tratamento de um distúrbio ocular, e, uso de micropartículas agregantes sólidas modificadas na superfície |
| DE102017002454A1 (de) * | 2017-03-14 | 2018-09-20 | Friedrich-Schiller-Universität Jena | Organische Polymerpartikel enthaltend Poly(oxazolin)-Stabilisatoren und Verwendung von Poly(oxazolinen) zur Stabilisierung von organischen Polymerpartikeln |
| JP7217022B2 (ja) | 2017-03-23 | 2023-02-02 | グレイバグ ビジョン インコーポレイテッド | 眼障害の治療のための薬物及び組成物 |
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| WO2020210805A1 (en) * | 2019-04-11 | 2020-10-15 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
| WO2021168239A1 (en) * | 2020-02-21 | 2021-08-26 | The Johns Hopkins University | Suprachoroidal delivery of drug particles to reduce toxicity |
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| US4888176A (en) | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
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| US4789724A (en) | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
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| US20050226814A1 (en) | 2004-04-13 | 2005-10-13 | Bausch & Lomb Incorporated | Diagnostic method and kit for implantation of a sustained release drug-delivery implant with a steroid |
| US20060089590A1 (en) * | 2004-10-27 | 2006-04-27 | John Higuchi | Methods and devices for sustained in-vivo release of an active agent |
| JP2007001926A (ja) * | 2005-06-24 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 吸入・噴霧用ステロイド製剤 |
| EP1985309B1 (en) * | 2005-12-26 | 2016-11-23 | LTT Bio-Pharma Co., Ltd. | Nanoparticles containing water-soluble non-peptide low-molecular weight drug |
| US20100129456A1 (en) * | 2007-05-14 | 2010-05-27 | Ltt Bio-Pharma Co., Ltd. | Sustained-release nanoparticle containing low-molecular-weight drug with negatively charged group |
| JP2011512903A (ja) * | 2008-02-25 | 2011-04-28 | アイゲート ファーマ エスエーエス | イオントフォレシスを介した眼組織への治療薬の向上した送達 |
| US20110206773A1 (en) * | 2008-05-20 | 2011-08-25 | Yale University | Sustained delivery of drugs from biodegradable polymeric microparticles |
| US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
| WO2011041373A1 (en) | 2009-09-29 | 2011-04-07 | Eyegate Pharmaceuticals, Inc. | Positively-charged poly (d,l-lactide-co-glycolide) nanoparticles and fabrication methods of the same |
| CA2845673A1 (en) | 2011-09-13 | 2013-03-21 | Altacor Limited | Pharmaceutical nanoparticle compositions |
| AU2013209452B2 (en) | 2012-01-19 | 2015-11-05 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
| NZ741873A (en) * | 2012-05-03 | 2019-04-26 | Kala Pharmaceuticals Inc | Pharmaceutical nanoparticles showing improved mucosal transport |
-
2015
- 2015-08-03 JP JP2017507390A patent/JP2017524712A/ja active Pending
- 2015-08-03 EP EP15756267.9A patent/EP3193827A1/en not_active Withdrawn
- 2015-08-03 KR KR1020177006811A patent/KR20170046146A/ko not_active Withdrawn
- 2015-08-03 WO PCT/US2015/043478 patent/WO2016025215A1/en not_active Ceased
- 2015-08-03 MX MX2017001863A patent/MX2017001863A/es unknown
- 2015-08-03 CN CN201580053822.9A patent/CN106794152A/zh active Pending
- 2015-08-03 US US15/502,732 patent/US10195212B2/en active Active
- 2015-08-03 CA CA2957764A patent/CA2957764C/en active Active
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|---|---|
| US20170157147A1 (en) | 2017-06-08 |
| CN106794152A (zh) | 2017-05-31 |
| MX2017001863A (es) | 2017-07-17 |
| CA2957764A1 (en) | 2016-02-18 |
| EP3193827A1 (en) | 2017-07-26 |
| WO2016025215A1 (en) | 2016-02-18 |
| US10195212B2 (en) | 2019-02-05 |
| KR20170046146A (ko) | 2017-04-28 |
| JP2017524712A (ja) | 2017-08-31 |
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