JP2017524372A5 - - Google Patents
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- JP2017524372A5 JP2017524372A5 JP2017515021A JP2017515021A JP2017524372A5 JP 2017524372 A5 JP2017524372 A5 JP 2017524372A5 JP 2017515021 A JP2017515021 A JP 2017515021A JP 2017515021 A JP2017515021 A JP 2017515021A JP 2017524372 A5 JP2017524372 A5 JP 2017524372A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- tcr
- nos
- isolated
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 41
- 108091008874 T cell receptors Proteins 0.000 claims 40
- 229920001184 polypeptide Polymers 0.000 claims 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 17
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 210000004027 cell Anatomy 0.000 claims 12
- 150000007523 nucleic acids Chemical group 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 7
- 102000036639 antigens Human genes 0.000 claims 7
- 238000003259 recombinant expression Methods 0.000 claims 7
- 239000013604 expression vector Substances 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 241000701806 Human papillomavirus Species 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- 241000341655 Human papillomavirus type 16 Species 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 208000006994 Precancerous Conditions Diseases 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 101000767631 Human papillomavirus type 16 Protein E7 Proteins 0.000 claims 1
- 208000002471 Penile Neoplasms Diseases 0.000 claims 1
- 208000004354 Vulvar Neoplasms Diseases 0.000 claims 1
- 210000002255 anal canal Anatomy 0.000 claims 1
- 210000003679 cervix uteri Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004335P | 2014-05-29 | 2014-05-29 | |
| US62/004,335 | 2014-05-29 | ||
| PCT/US2015/033129 WO2015184228A1 (en) | 2014-05-29 | 2015-05-29 | Anti-human papillomavirus 16 e7 t cell receptors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020127833A Division JP6997267B2 (ja) | 2014-05-29 | 2020-07-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524372A JP2017524372A (ja) | 2017-08-31 |
| JP2017524372A5 true JP2017524372A5 (cg-RX-API-DMAC7.html) | 2018-06-28 |
| JP6742991B2 JP6742991B2 (ja) | 2020-08-19 |
Family
ID=53396593
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017515021A Active JP6742991B2 (ja) | 2014-05-29 | 2015-05-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2020127833A Active JP6997267B2 (ja) | 2014-05-29 | 2020-07-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2021203953A Active JP7291196B2 (ja) | 2014-05-29 | 2021-12-16 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2023091878A Active JP7535158B2 (ja) | 2014-05-29 | 2023-06-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2024126652A Active JP7744479B2 (ja) | 2014-05-29 | 2024-08-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020127833A Active JP6997267B2 (ja) | 2014-05-29 | 2020-07-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2021203953A Active JP7291196B2 (ja) | 2014-05-29 | 2021-12-16 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2023091878A Active JP7535158B2 (ja) | 2014-05-29 | 2023-06-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2024126652A Active JP7744479B2 (ja) | 2014-05-29 | 2024-08-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
Country Status (21)
Families Citing this family (70)
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| PL3149031T3 (pl) | 2014-05-29 | 2020-08-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Receptory limfocytów t przeciwko e7 wirusa brodawczaka ludzkiego 16 |
| US10544392B2 (en) * | 2015-05-01 | 2020-01-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
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| WO2017139199A1 (en) | 2016-02-10 | 2017-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inducible arginase |
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| AU2018341244A1 (en) | 2017-09-26 | 2020-03-05 | Cero Therapeutics, Inc. | Chimeric engulfment receptor molecules and methods of use |
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| US11952408B2 (en) | 2017-10-03 | 2024-04-09 | Juno Therapeutics, Inc. | HPV-specific binding molecules |
| CA3077595A1 (en) | 2017-10-05 | 2019-04-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for diagnosing, monitoring and treating neurological diseases and disorders |
| CN111556893A (zh) | 2017-11-06 | 2020-08-18 | 爱迪塔斯医药股份有限公司 | 免疫疗法t细胞中cblb的crispr-cas9编辑的方法、组合物和组分 |
| EP3737692A4 (en) | 2018-01-09 | 2021-09-29 | Elstar Therapeutics, Inc. | CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES |
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| RU2020135968A (ru) * | 2018-04-05 | 2022-05-06 | Джуно Терапьютикс, Инк. | T-клеточные рецепторы и модифицированные клетки, экспрессирующие |
| US20210015869A1 (en) | 2018-04-05 | 2021-01-21 | Juno Therapeutics, Inc. | T cells expressing a recombinant receptor, related polynucleotides and methods |
| US12415845B2 (en) | 2018-04-24 | 2025-09-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of producing T cell populations using hydroxycitric acid and/or a salt thereof |
| WO2019243888A1 (en) * | 2018-06-22 | 2019-12-26 | Kite Pharma Eu B.V. | Compositions and methods for making engineered t cells |
| EP3818083A2 (en) | 2018-07-03 | 2021-05-12 | Elstar Therapeutics, Inc. | Anti-tcr antibody molecules and uses thereof |
| WO2020033927A2 (en) | 2018-08-09 | 2020-02-13 | Juno Therapeutics, Inc. | Processes for generating engineered cells and compositions thereof |
| JP7504891B2 (ja) | 2018-09-11 | 2024-06-24 | ジュノー セラピューティクス インコーポレイテッド | 操作された細胞組成物のマススペクトロメトリー分析のための方法 |
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| KR20220016475A (ko) | 2019-05-01 | 2022-02-09 | 주노 쎄러퓨티크스 인코퍼레이티드 | 변형된 ｔｇｆｂｒ2 유전자 좌에서 재조합 수용체를 발현하는 세포, 관련 폴리뉴클레오티드 및 방법 |
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| US20240148869A1 (en) * | 2020-05-07 | 2024-05-09 | China Immunotech (Beijing) Biotechnology Co., Ltd | Improved T cell receptor-costimulatory molecule chimera |
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| PL3149031T3 (pl) * | 2014-05-29 | 2020-08-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Receptory limfocytów t przeciwko e7 wirusa brodawczaka ludzkiego 16 |
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2015
- 2015-05-29 PL PL15729004T patent/PL3149031T3/pl unknown
- 2015-05-29 BR BR112016027805A patent/BR112016027805A2/pt active IP Right Grant
- 2015-05-29 AU AU2015266818A patent/AU2015266818B2/en active Active
- 2015-05-29 SM SM20200143T patent/SMT202000143T1/it unknown
- 2015-05-29 CA CA2950192A patent/CA2950192A1/en active Pending
- 2015-05-29 EP EP19217074.4A patent/EP3689900B1/en active Active
- 2015-05-29 PT PT157290040T patent/PT3149031T/pt unknown
- 2015-05-29 LT LTEP15729004.0T patent/LT3149031T/lt unknown
- 2015-05-29 ES ES15729004T patent/ES2784237T3/es active Active
- 2015-05-29 WO PCT/US2015/033129 patent/WO2015184228A1/en not_active Ceased
- 2015-05-29 US US15/313,673 patent/US10174098B2/en active Active
- 2015-05-29 CN CN201580031789.XA patent/CN106661098B/zh active Active
- 2015-05-29 EP EP15729004.0A patent/EP3149031B1/en active Active
- 2015-05-29 EP EP25187143.0A patent/EP4609876A2/en active Pending
- 2015-05-29 KR KR1020167033189A patent/KR102445667B1/ko active Active
- 2015-05-29 IL IL290655A patent/IL290655B2/en unknown
- 2015-05-29 KR KR1020227032043A patent/KR102618267B1/ko active Active
- 2015-05-29 HR HRP20200376TT patent/HRP20200376T1/hr unknown
- 2015-05-29 CN CN202110399056.9A patent/CN113150112B/zh active Active
- 2015-05-29 MX MX2016015383A patent/MX375379B/es active IP Right Grant
- 2015-05-29 JP JP2017515021A patent/JP6742991B2/ja active Active
- 2015-05-29 DK DK15729004.0T patent/DK3149031T3/da active
- 2015-05-29 SI SI201531126T patent/SI3149031T1/sl unknown
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2016
- 2016-11-07 IL IL248797A patent/IL248797B/en active IP Right Grant
- 2016-11-24 MX MX2020010035A patent/MX2020010035A/es unknown
- 2016-11-29 SA SA516380394A patent/SA516380394B1/ar unknown
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2018
- 2018-11-30 US US16/205,631 patent/US10870687B2/en active Active
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2019
- 2019-12-18 AU AU2019283892A patent/AU2019283892B2/en active Active
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2020
- 2020-03-16 CY CY20201100238T patent/CY1122790T1/el unknown
- 2020-07-29 JP JP2020127833A patent/JP6997267B2/ja active Active
- 2020-11-23 US US17/101,360 patent/US11434272B2/en active Active
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2021
- 2021-04-13 AU AU2021202227A patent/AU2021202227B2/en active Active
- 2021-04-21 IL IL282518A patent/IL282518B/en unknown
- 2021-12-16 JP JP2021203953A patent/JP7291196B2/ja active Active
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2022
- 2022-08-01 US US17/816,496 patent/US20220372103A1/en active Pending
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2023
- 2023-02-06 AU AU2023200608A patent/AU2023200608B2/en active Active
- 2023-06-02 JP JP2023091878A patent/JP7535158B2/ja active Active
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2024
- 2024-08-02 JP JP2024126652A patent/JP7744479B2/ja active Active
- 2024-11-19 AU AU2024266702A patent/AU2024266702A1/en not_active Abandoned
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