JP2017522300A5 - - Google Patents
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- Publication number
- JP2017522300A5 JP2017522300A5 JP2016575499A JP2016575499A JP2017522300A5 JP 2017522300 A5 JP2017522300 A5 JP 2017522300A5 JP 2016575499 A JP2016575499 A JP 2016575499A JP 2016575499 A JP2016575499 A JP 2016575499A JP 2017522300 A5 JP2017522300 A5 JP 2017522300A5
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- benzoxazin
- oxo
- carbonyl
- acetamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462018790P | 2014-06-30 | 2014-06-30 | |
| US62/018,790 | 2014-06-30 | ||
| PCT/GB2015/051860 WO2016001631A1 (en) | 2014-06-30 | 2015-06-26 | Benzoxazinone amides as mineralocorticoid receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017522300A JP2017522300A (ja) | 2017-08-10 |
| JP2017522300A5 true JP2017522300A5 (https=) | 2018-07-19 |
| JP6368383B2 JP6368383B2 (ja) | 2018-08-01 |
Family
ID=53539739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016575499A Active JP6368383B2 (ja) | 2014-06-30 | 2015-06-26 | 鉱質コルチコイド受容体修飾因子としてのベンゾオキサジノンアミド |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US10017502B2 (https=) |
| EP (1) | EP3160948B1 (https=) |
| JP (1) | JP6368383B2 (https=) |
| KR (1) | KR102012222B1 (https=) |
| CN (1) | CN106536491B (https=) |
| AR (1) | AR101036A1 (https=) |
| AU (1) | AU2015282450C1 (https=) |
| CA (1) | CA2953655C (https=) |
| CY (1) | CY1121596T1 (https=) |
| DK (1) | DK3160948T3 (https=) |
| EA (1) | EA029518B1 (https=) |
| ES (1) | ES2707726T3 (https=) |
| HR (1) | HRP20190147T1 (https=) |
| HU (1) | HUE042370T2 (https=) |
| LT (1) | LT3160948T (https=) |
| ME (1) | ME03316B (https=) |
| MX (1) | MX367404B (https=) |
| PL (1) | PL3160948T3 (https=) |
| PT (1) | PT3160948T (https=) |
| RS (1) | RS58274B1 (https=) |
| SI (1) | SI3160948T1 (https=) |
| SM (1) | SMT201900039T1 (https=) |
| TR (1) | TR201900659T4 (https=) |
| TW (1) | TWI677498B (https=) |
| UY (1) | UY36195A (https=) |
| WO (1) | WO2016001631A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3160948B1 (en) * | 2014-06-30 | 2018-10-24 | Astrazeneca AB | Benzoxazinone amides as mineralocorticoid receptor modulators |
| MA53175A (fr) | 2018-07-19 | 2021-05-26 | Astrazeneca Ab | Méthodes de traitement de hfpef au moyen de dapagliflozine et compositions comprenant celle-ci |
| CN112107568B (zh) * | 2019-06-19 | 2022-03-25 | 北京龙嘉博创医药科技有限公司 | 二芳基酰胺类化合物及其应用 |
| PE20211267A1 (es) | 2019-08-30 | 2021-07-19 | Astrazeneca Ab | Metodos de tratamiento de la insuficiencia cardiaca con fraccion de eyeccion reducida con dapagliflozina |
| CN116392472B (zh) | 2020-07-27 | 2025-06-20 | 阿斯利康(瑞典)有限公司 | 用达格列净治疗慢性肾脏病的方法 |
| US12409186B2 (en) | 2020-07-27 | 2025-09-09 | Astrazeneca Ab | Methods of treating chronic kidney disease with dapagliflozin |
| MX2023015144A (es) | 2021-06-15 | 2024-01-22 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Derivados de benzoxazinona. |
| TW202409023A (zh) | 2022-07-14 | 2024-03-01 | 美商富曼西公司 | 除草苯并𠯤 |
| AU2023331475A1 (en) | 2022-09-01 | 2025-04-17 | Astrazeneca Ab | Combination of sglt2 inhibitors and mineralcorticoid receptor modulators for use in treatment of cardiorenal diseases |
| WO2024125591A1 (zh) * | 2022-12-15 | 2024-06-20 | 正大天晴药业集团股份有限公司 | 苯并恶嗪酮类化合物的结晶及其制备 |
| WO2025111184A1 (en) | 2023-11-21 | 2025-05-30 | Fmc Corporation | Substituted tetrahydroquinoline and tetrahydroquinoxaline herbicides |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6951855B2 (en) * | 2001-04-23 | 2005-10-04 | Astrazeneca Ab | Benzoxazinone derivatives for use in the treatment of angiogenesis |
| CA2510851A1 (en) * | 2002-12-20 | 2004-07-08 | Warner-Lambert Company Llc | Benzoxazines and derivatives thereof as inhibitors of pi3ks |
| CN101018552A (zh) * | 2004-07-14 | 2007-08-15 | 利亘制药公司 | 细胞内受体调节剂化合物和方法 |
| US20090054417A1 (en) * | 2004-07-28 | 2009-02-26 | Irm Llc | Compounds and compositions as modulators of steroid hormone nuclear receptors |
| CA2635541A1 (en) | 2005-12-28 | 2007-07-12 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compounds and their use as mineralocorticoid receptor ligands |
| TWI385161B (zh) | 2006-02-02 | 2013-02-11 | Mitsubishi Tanabe Pharma Corp | 含氮雜雙環化合物 |
| DK2089367T3 (da) | 2006-10-31 | 2012-02-06 | Pfizer Prod Inc | Pyrazolinforbindelser som mineralocorticoidreceptor-antagonister |
| DE102007009494A1 (de) | 2007-02-27 | 2008-08-28 | Bayer Healthcare Ag | Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung |
| EP2139489A4 (en) | 2007-03-23 | 2011-11-02 | Merck Sharp & Dohme | Mineralocorticoid receptor modulators |
| EP2133330B1 (en) | 2007-04-09 | 2014-01-01 | Daiichi Sankyo Company, Limited | Atropisomer of pyrrole derivative |
| JP5173653B2 (ja) * | 2007-08-01 | 2013-04-03 | 田辺三菱製薬株式会社 | 医薬組成物 |
| US8258131B2 (en) | 2007-08-01 | 2012-09-04 | Mitsubishi Tanabe Pharma Corporation | Fused bicyclic compound |
| TWI431010B (zh) | 2007-12-19 | 2014-03-21 | Lilly Co Eli | 礦皮質素受體拮抗劑及使用方法 |
| UY31905A (es) * | 2008-06-18 | 2010-01-29 | Astrazeneca Ab | Derivados de benzoxazinona, procesos de preparación, composiciones farmacéuticas conteniéndolos y aplicaciones. |
| US20100094000A1 (en) | 2008-09-03 | 2010-04-15 | Takeda Pharmaceutical Company Limited | Pyrazole compounds |
| WO2010098286A1 (ja) | 2009-02-25 | 2010-09-02 | 第一三共株式会社 | ミネラルコルチコイド受容体拮抗薬を含有する医薬 |
| WO2010104721A1 (en) | 2009-03-12 | 2010-09-16 | Eli Lilly And Company | Mineralocorticoid receptor antagonist and methods of use |
| JP2012523405A (ja) | 2009-04-10 | 2012-10-04 | ファイザー・インク | ４，５−ジヒドロ−１ｈ−ピラゾール化合物およびその薬学的使用 |
| WO2011141848A1 (en) | 2010-05-11 | 2011-11-17 | Pfizer Inc. | Morpholine compounds as mineralocorticoid receptor antagonists |
| WO2011141846A2 (en) | 2010-05-11 | 2011-11-17 | Koninklijke Philips Electronics N.V. | Lighting module |
| US20130116227A1 (en) | 2010-07-13 | 2013-05-09 | Dainippon Sumitomo Pharma Co., Ltd. | Biaryl amide derivative or pharmaceutically acceptable salt thereof |
| JP2013542255A (ja) | 2010-11-10 | 2013-11-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ミネラルコルチコイド受容体アンタゴニストとしてのピリジル尿素 |
| EP3160948B1 (en) * | 2014-06-30 | 2018-10-24 | Astrazeneca AB | Benzoxazinone amides as mineralocorticoid receptor modulators |
-
2015
- 2015-06-26 EP EP15736015.7A patent/EP3160948B1/en active Active
- 2015-06-26 KR KR1020177002518A patent/KR102012222B1/ko active Active
- 2015-06-26 LT LTEP15736015.7T patent/LT3160948T/lt unknown
- 2015-06-26 CA CA2953655A patent/CA2953655C/en active Active
- 2015-06-26 JP JP2016575499A patent/JP6368383B2/ja active Active
- 2015-06-26 MX MX2017000183A patent/MX367404B/es active IP Right Grant
- 2015-06-26 SI SI201530572T patent/SI3160948T1/sl unknown
- 2015-06-26 SM SM20190039T patent/SMT201900039T1/it unknown
- 2015-06-26 WO PCT/GB2015/051860 patent/WO2016001631A1/en not_active Ceased
- 2015-06-26 ES ES15736015T patent/ES2707726T3/es active Active
- 2015-06-26 PL PL15736015T patent/PL3160948T3/pl unknown
- 2015-06-26 HU HUE15736015A patent/HUE042370T2/hu unknown
- 2015-06-26 US US15/320,379 patent/US10017502B2/en active Active
- 2015-06-26 CN CN201580035032.8A patent/CN106536491B/zh active Active
- 2015-06-26 EA EA201790046A patent/EA029518B1/ru not_active IP Right Cessation
- 2015-06-26 PT PT15736015T patent/PT3160948T/pt unknown
- 2015-06-26 HR HRP20190147TT patent/HRP20190147T1/hr unknown
- 2015-06-26 ME MEP-2019-19A patent/ME03316B/me unknown
- 2015-06-26 RS RS20190085A patent/RS58274B1/sr unknown
- 2015-06-26 TR TR2019/00659T patent/TR201900659T4/tr unknown
- 2015-06-26 AU AU2015282450A patent/AU2015282450C1/en active Active
- 2015-06-26 UY UY0001036195A patent/UY36195A/es not_active Application Discontinuation
- 2015-06-26 DK DK15736015.7T patent/DK3160948T3/en active
- 2015-06-29 US US14/753,239 patent/US9394291B2/en active Active
- 2015-06-29 TW TW104120998A patent/TWI677498B/zh active
- 2015-06-30 AR ARP150102098A patent/AR101036A1/es active IP Right Grant
-
2019
- 2019-01-24 CY CY20191100097T patent/CY1121596T1/el unknown