JP2017522004A5 - - Google Patents
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- Publication number
- JP2017522004A5 JP2017522004A5 JP2016568430A JP2016568430A JP2017522004A5 JP 2017522004 A5 JP2017522004 A5 JP 2017522004A5 JP 2016568430 A JP2016568430 A JP 2016568430A JP 2016568430 A JP2016568430 A JP 2016568430A JP 2017522004 A5 JP2017522004 A5 JP 2017522004A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antisense morpholino
- morpholino oligomer
- formula
- cpp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462000431P | 2014-05-19 | 2014-05-19 | |
| US62/000,431 | 2014-05-19 | ||
| US201562129746P | 2015-03-06 | 2015-03-06 | |
| US62/129,746 | 2015-03-06 | ||
| PCT/US2015/031213 WO2015179249A1 (en) | 2014-05-19 | 2015-05-15 | Antisense antibacterial compounds and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017522004A JP2017522004A (ja) | 2017-08-10 |
| JP2017522004A5 true JP2017522004A5 (cg-RX-API-DMAC10.html) | 2018-06-21 |
| JP6687542B2 JP6687542B2 (ja) | 2020-04-22 |
Family
ID=54554572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016568430A Active JP6687542B2 (ja) | 2014-05-19 | 2015-05-15 | アンチセンス抗菌化合物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10391098B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP3569252B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6687542B2 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2015264449B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2948568A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2015179249A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0992230A3 (en) | 1998-10-08 | 2001-08-22 | KCI Licensing, Inc. | Medical pumping apparatus and related methods |
| US9790495B2 (en) | 2014-05-16 | 2017-10-17 | Oregon State University | Antisense antibacterial compounds and methods |
| CA2948568A1 (en) | 2014-05-19 | 2015-11-26 | David Greenberg | Antisense antibacterial compounds and methods |
| WO2016108930A2 (en) | 2014-12-31 | 2016-07-07 | Geller Bruce L | Antisense antibacterial compounds and methods |
| US11142764B2 (en) | 2015-12-23 | 2021-10-12 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| AU2016379399B2 (en) * | 2015-12-23 | 2022-12-08 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| JP7042255B2 (ja) * | 2016-04-29 | 2022-03-25 | サレプタ セラピューティクス， インコーポレイテッド | ヒトｌｍｎａを標的にするオリゴヌクレオチド類縁体 |
| US20200283768A1 (en) * | 2017-10-23 | 2020-09-10 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| GB2579253A (en) | 2018-11-28 | 2020-06-17 | Pedanius Therapeutics Ltd | Antibacterial antisense agents |
| CN110885364B (zh) * | 2019-12-26 | 2021-02-02 | 江南大学 | 一种促进N-乙酰氨基葡萄糖生产的RamA转录因子突变体及其应用 |
| WO2025165798A1 (en) * | 2024-01-30 | 2025-08-07 | Gene Company (Pty) Ltd. | POLYNUCLEOTIDE TARGETING RNA POLYMERASE PRIMARY σ70 AND METHOD OF USE AND TREATMENT THEREOF |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5506337A (en) | 1985-03-15 | 1996-04-09 | Antivirals Inc. | Morpholino-subunit combinatorial library and method |
| US5521063A (en) | 1985-03-15 | 1996-05-28 | Antivirals Inc. | Polynucleotide reagent containing chiral subunits and methods of use |
| JP2528107B2 (ja) | 1985-03-15 | 1996-08-28 | サマ−トン，ジエ−ムス | ポリヌクレオチド測定試薬と方法 |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5217866A (en) | 1985-03-15 | 1993-06-08 | Anti-Gene Development Group | Polynucleotide assay reagent and method |
| US5185444A (en) | 1985-03-15 | 1993-02-09 | Anti-Gene Deveopment Group | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages |
| US5166315A (en) | 1989-12-20 | 1992-11-24 | Anti-Gene Development Group | Sequence-specific binding polymers for duplex nucleic acids |
| AU659482B2 (en) | 1991-06-28 | 1995-05-18 | Massachusetts Institute Of Technology | Localized oligonucleotide therapy |
| WO1997022371A1 (en) | 1995-12-18 | 1997-06-26 | Collagen Corporation | Crosslinked polymer compositions and methods for their use |
| US6245747B1 (en) | 1996-03-12 | 2001-06-12 | The Board Of Regents Of The University Of Nebraska | Targeted site specific antisense oligodeoxynucleotide delivery method |
| US20060241075A1 (en) | 2001-05-18 | 2006-10-26 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA) |
| US20040029129A1 (en) | 2001-10-25 | 2004-02-12 | Liangsu Wang | Identification of essential genes in microorganisms |
| US6965025B2 (en) | 2001-12-10 | 2005-11-15 | Isis Pharmaceuticals, Inc. | Antisense modulation of connective tissue growth factor expression |
| AU2004231740A1 (en) | 2003-04-17 | 2004-11-04 | The Trustees Of Columbia University In The City Ofnew York | Desmoglein 4 is a novel gene involved in hair growth |
| AU2004235396B2 (en) | 2003-04-29 | 2010-11-25 | Sarepta Therapeutics, Inc. | Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells |
| US20050288246A1 (en) * | 2004-05-24 | 2005-12-29 | Iversen Patrick L | Peptide conjugated, inosine-substituted antisense oligomer compound and method |
| AU2005327188C9 (en) | 2004-07-02 | 2011-09-22 | Avi Biopharma, Inc. | Antisense antibacterial method and compound |
| US20070154896A1 (en) | 2005-02-11 | 2007-07-05 | International Business Machines Corporation | System and method for identification of MicroRNA target sites and corresponding targeting MicroRNA sequences |
| AU2006267051B2 (en) * | 2005-07-13 | 2013-03-07 | Sarepta Therapeutics, Inc. | Antisense antibacterial method and compound |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| US7790694B2 (en) | 2005-07-13 | 2010-09-07 | Avi Biopharma Inc. | Antisense antibacterial method and compound |
| US8143389B2 (en) | 2005-08-25 | 2012-03-27 | Texas Tech University | Inhibiton of metallo-β-lactamase by double-stranded DNA |
| CA2691673A1 (en) | 2007-06-29 | 2009-01-08 | Avi Biopharma, Inc. | Tissue specific peptide conjugates and methods |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| US8299206B2 (en) | 2007-11-15 | 2012-10-30 | Avi Biopharma, Inc. | Method of synthesis of morpholino oligomers |
| MX2010004955A (es) | 2007-11-15 | 2010-06-30 | Avi Biopharma Inc | Metodo de sintesis de oligomeros de morfolina. |
| US8076476B2 (en) | 2007-11-15 | 2011-12-13 | Avi Biopharma, Inc. | Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits |
| US20110269665A1 (en) | 2009-06-26 | 2011-11-03 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| WO2011018798A2 (en) | 2009-08-14 | 2011-02-17 | Indian Association For The Cultivation Of Science | Morpholino-based antisense agent |
| WO2012031243A2 (en) | 2010-09-03 | 2012-03-08 | Avi Biopharma, Inc. | dsRNA MOLECULES COMPRISING OLIGONUCLEOTIDE ANALOGS HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS |
| CN103154009B (zh) | 2010-09-30 | 2015-06-10 | 日本新药株式会社 | 吗啉基核酸衍生物 |
| AU2011326364B2 (en) | 2010-11-12 | 2016-08-11 | Sarepta Therapeutics, Inc. | Antisense antibacterial compounds and methods |
| US20120213663A1 (en) | 2011-02-23 | 2012-08-23 | King Fahd University Of Petroleum And Minerals | Method of removing e. coli bacteria from an aqueous solution |
| AU2011367230B2 (en) | 2011-05-05 | 2017-08-10 | Sarepta Therapeutics, Inc. | Peptide oligonucleotide conjugates |
| US9161948B2 (en) | 2011-05-05 | 2015-10-20 | Sarepta Therapeutics, Inc. | Peptide oligonucleotide conjugates |
| KR101317263B1 (ko) | 2011-07-05 | 2013-10-10 | (주)지노첵 | 리얼타임 ｐｃｒ을 이용한 카바페넴 내성 장내균 검사 방법 및 키트 |
| WO2013011072A1 (en) | 2011-07-20 | 2013-01-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Carbapenemase and antibacterial treatment |
| US9790495B2 (en) | 2014-05-16 | 2017-10-17 | Oregon State University | Antisense antibacterial compounds and methods |
| CA2948568A1 (en) | 2014-05-19 | 2015-11-26 | David Greenberg | Antisense antibacterial compounds and methods |
| WO2016108930A2 (en) | 2014-12-31 | 2016-07-07 | Geller Bruce L | Antisense antibacterial compounds and methods |
| AU2016379399B2 (en) | 2015-12-23 | 2022-12-08 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| US11142764B2 (en) | 2015-12-23 | 2021-10-12 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
-
2015
- 2015-05-15 CA CA2948568A patent/CA2948568A1/en active Pending
- 2015-05-15 EP EP19167404.3A patent/EP3569252B1/en active Active
- 2015-05-15 WO PCT/US2015/031213 patent/WO2015179249A1/en not_active Ceased
- 2015-05-15 AU AU2015264449A patent/AU2015264449B2/en active Active
- 2015-05-15 US US14/714,104 patent/US10391098B2/en active Active
- 2015-05-15 JP JP2016568430A patent/JP6687542B2/ja active Active
- 2015-05-15 EP EP15795398.5A patent/EP3146047A4/en not_active Withdrawn
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