JP2017519839A5 - - Google Patents
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- Publication number
- JP2017519839A5 JP2017519839A5 JP2017520772A JP2017520772A JP2017519839A5 JP 2017519839 A5 JP2017519839 A5 JP 2017519839A5 JP 2017520772 A JP2017520772 A JP 2017520772A JP 2017520772 A JP2017520772 A JP 2017520772A JP 2017519839 A5 JP2017519839 A5 JP 2017519839A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pridopidine
- concentration
- area
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462019337P | 2014-06-30 | 2014-06-30 | |
| US62/019,337 | 2014-06-30 | ||
| US201462076436P | 2014-11-06 | 2014-11-06 | |
| US62/076,436 | 2014-11-06 | ||
| PCT/US2015/038349 WO2016003919A1 (en) | 2014-06-30 | 2015-06-29 | Analogs of pridopidine, their preparation and use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020077160A Division JP7035108B2 (ja) | 2014-06-30 | 2020-04-24 | プリドピジンの類似体、それらの製造および使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017519839A JP2017519839A (ja) | 2017-07-20 |
| JP2017519839A5 true JP2017519839A5 (enExample) | 2018-08-09 |
| JP6800842B2 JP6800842B2 (ja) | 2020-12-16 |
Family
ID=54929343
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017520772A Active JP6800842B2 (ja) | 2014-06-30 | 2015-06-29 | プリドピジンの類似体、それらの製造および使用 |
| JP2020077160A Active JP7035108B2 (ja) | 2014-06-30 | 2020-04-24 | プリドピジンの類似体、それらの製造および使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020077160A Active JP7035108B2 (ja) | 2014-06-30 | 2020-04-24 | プリドピジンの類似体、それらの製造および使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10130621B2 (enExample) |
| EP (2) | EP3160470B1 (enExample) |
| JP (2) | JP6800842B2 (enExample) |
| CN (2) | CN106456618A (enExample) |
| AU (1) | AU2015284385B2 (enExample) |
| BR (1) | BR112016030968B1 (enExample) |
| CA (1) | CA2951494C (enExample) |
| DK (1) | DK3160470T3 (enExample) |
| EA (1) | EA201790101A1 (enExample) |
| ES (1) | ES2927888T3 (enExample) |
| HU (1) | HUE060242T2 (enExample) |
| IL (2) | IL249601B (enExample) |
| MX (1) | MX382649B (enExample) |
| PL (1) | PL3160470T3 (enExample) |
| TW (1) | TW201613859A (enExample) |
| UY (1) | UY36192A (enExample) |
| WO (1) | WO2016003919A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| JP2013536825A (ja) | 2010-09-03 | 2013-09-26 | イバックス・インターナショナル・ゲーエムベーハー | ドパミン作動性安定化剤として有用なプリドピジンの重水素化類似体 |
| TWI579272B (zh) | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| US11090297B2 (en) * | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| HK1221646A1 (zh) | 2013-06-21 | 2017-06-09 | Teva Pharmaceuticals International Gmbh | 高剂量普利多匹定用於治疗亨廷顿舞蹈症的用途 |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| MX2017008136A (es) | 2014-12-22 | 2018-03-06 | Teva Pharmaceuticals Int Gmbh | Sal de l-tartrato de pridopidina. |
| US11471449B2 (en) | 2015-02-25 | 2022-10-18 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| JP6887952B2 (ja) | 2015-02-25 | 2021-06-16 | プリレニア ニューロセラピューティクス リミテッド | 認知機能を改善するため、およびアルツハイマー病を治療するためのプリドピジンの使用 |
| AR105434A1 (es) | 2015-07-22 | 2017-10-04 | Teva Pharmaceuticals Int Gmbh | Proceso para preparar pridopidina |
| JP7034488B2 (ja) | 2016-02-24 | 2022-03-14 | プリレニア・ニューロセラピューティクス・エルティーディー | プリドピジンを使用する神経変性眼疾患の治療 |
| CA3035099C (en) | 2016-08-24 | 2023-01-17 | Prilenia Therapeutics Development Ltd. | Use of pridopidine for treating dystonias |
| EP4516356A3 (en) | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| CA3050700C (en) | 2017-01-20 | 2023-10-03 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for the treatment of fragile x syndrome |
| SI4154882T1 (sl) | 2017-08-14 | 2026-01-30 | Prilenia Neurotherapeutics Ltd. | Zdravljenje amiotrofične lateralne skleroze s pridopidinom |
| CA3073568A1 (en) | 2017-08-30 | 2019-03-07 | Prilenia Neurotherapeutics Ltd. | High concentration dosage forms of pridopidine |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| JP2020533296A (ja) | 2017-09-08 | 2020-11-19 | プリレニア ニューロセラピューティクス リミテッド | 薬物誘発性ジスキネジアを治療するためのプリドピジン |
| CN113395964A (zh) | 2019-02-04 | 2021-09-14 | 普瑞尼亚神经治疗有限公司 | 用于帕金森氏病和与帕金森症相关的其它疾病的低剂量普利多匹定 |
| AU2020243692B2 (en) * | 2019-03-15 | 2023-03-02 | Prilenia Neurotherapeutics Ltd. | Treatment of mitochondrial associated diseases and disorders, including symptoms thereof using pridopidine |
| CN121243170A (zh) | 2019-06-12 | 2026-01-02 | 普瑞尼亚神经治疗有限公司 | 用于治疗亨廷顿病及其症状的包含普利多匹定及其类似物的组合物 |
| CA3176917A1 (en) * | 2020-05-04 | 2021-11-11 | Prilenia Neurotherapeutics Ltd. | Treatment of viral infection, disease or disorder using a selective s1r agonist |
| MX2023004516A (es) * | 2020-10-20 | 2023-05-04 | Prilenia Neurotherapeutics Ltd | Uso de pridopidina y analogos para el tratamiento de la ansiedad y la depresion. |
| CN116472043A (zh) * | 2020-10-20 | 2023-07-21 | 普瑞尼亚神经治疗有限公司 | 普利多匹定和类似物用于治疗焦虑和抑郁的用途 |
| IL307462A (en) * | 2021-04-14 | 2023-12-01 | Prilenia Neurotherapeutics Ltd | Treatment of prodromal huntington disease |
| JP7829678B2 (ja) * | 2021-10-11 | 2026-03-13 | プリレニア ニューロセラピューティクス リミテッド | 神経変性眼疾患を治療するためのプリドピジン及びその類似体 |
| CN114716391B (zh) * | 2022-04-24 | 2023-12-12 | 杭州仟源保灵药业有限公司 | 一种醋甲唑胺杂质及其制备方法和应用 |
| EP4519246A4 (en) * | 2022-05-03 | 2025-08-13 | Prilenia Neurotherapeutics Ltd | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE |
| CN118924710A (zh) * | 2024-08-05 | 2024-11-12 | 四川大学 | 细辛脑在制备治疗和/或预防眼部疾病药物中的应用和一种组合物及其应用 |
| WO2026035949A1 (en) * | 2024-08-08 | 2026-02-12 | Prilenia Therapeutics Inc. | Combination of pridopidine and low dose anti-dopaminergic medication (adm) for treating huntington disease and sympto thereof |
| WO2026080658A1 (en) | 2024-10-10 | 2026-04-16 | Prilenia Therapeutics Inc. | Pridopidine for the treatment of distal hereditary motor neuropathy (dhmn) |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6472736A (en) | 1987-09-14 | 1989-03-17 | Toshiba Corp | Mri apparatus |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| JP2007522130A (ja) * | 2004-01-21 | 2007-08-09 | テバ ファーマシューティカル インダストリーズ リミティド | 塩酸バラシクロビルの調製方法 |
| ATE449071T1 (de) * | 2004-06-08 | 2009-12-15 | Nsab Af Neurosearch Sweden Ab | Neue substituierte piperidine als modulatoren der dopamin neurotransmission |
| SE0401465D0 (sv) | 2004-06-08 | 2004-06-08 | Carlsson A Research Ab | New substituted piperdines as modulators of dopamine neurotransmission |
| CA2578750A1 (en) * | 2004-09-04 | 2006-03-16 | Teva Pharmaceutical Industries, Ltd. | A valacyclovir impurity, process for the preparation of valacyclovir impurity and use as a reference standard |
| EP1807394A1 (en) * | 2004-10-13 | 2007-07-18 | Neurosearch Sweden AB | Process for the synthesis of 4-(3-sulfonylphenyl)-piperidines |
| CA2584831C (en) * | 2004-10-13 | 2013-09-17 | Neurosearch Sweden Ab | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine |
| EP1716139A1 (en) * | 2005-01-03 | 2006-11-02 | Teva Pharmaceutical Industries Ltd. | Olmesartan medoxomil with reduced levels of impurities |
| SE529246C2 (sv) * | 2005-10-13 | 2007-06-12 | Neurosearch Sweden Ab | Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission |
| EP1961742A1 (en) | 2007-02-22 | 2008-08-27 | Novartis AG | compounds of formula (I) as serine protease inhibitors |
| CN101711236B (zh) | 2007-04-12 | 2012-10-31 | Nsab神经研究瑞典公司分公司 | 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 |
| WO2008155357A2 (en) * | 2007-06-18 | 2008-12-24 | A. Carlsson Research Ab | Use of dopamine stabilizers |
| US20110206782A1 (en) * | 2010-02-24 | 2011-08-25 | Auspex Pharmaceuticals, Inc. | Piperidine modulators of dopamine receptor |
| JP2013532233A (ja) | 2010-07-02 | 2013-08-15 | アクティエボラゲット・エスコーエッフ | 機械構成要素、および表面硬化方法 |
| JP2013536825A (ja) | 2010-09-03 | 2013-09-26 | イバックス・インターナショナル・ゲーエムベーハー | ドパミン作動性安定化剤として有用なプリドピジンの重水素化類似体 |
| BR112014005389A8 (pt) | 2011-09-07 | 2018-04-03 | Ivax Int Gmbh | Sal cloridrato de 4- (3-metanossulfonil-fenil) -1- propil-piperidina em uma forma cristalina, composição farmacêutica compreendendo o mesmo e usos do dito sal |
| TWI579272B (zh) | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| AU2013243461A1 (en) | 2012-04-04 | 2014-11-06 | Teva Pharmaceuticals International Gmbh | Pharmaceutical compositions for combination therapy |
| MX2015003608A (es) | 2012-09-27 | 2015-06-05 | Teva Pharma | Combinacion de laquinimod y pridopidina para tratar trastornos neurodegenerativos. |
| US20150216850A1 (en) | 2012-09-27 | 2015-08-06 | Michael Hayden | Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| HK1221646A1 (zh) | 2013-06-21 | 2017-06-09 | Teva Pharmaceuticals International Gmbh | 高剂量普利多匹定用於治疗亨廷顿舞蹈症的用途 |
| MX377576B (es) | 2014-01-22 | 2025-03-04 | Prilenia Neurotherapeutics Ltd | Formulaciones de pridopidina de liberación modificada. |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| MX2017008136A (es) | 2014-12-22 | 2018-03-06 | Teva Pharmaceuticals Int Gmbh | Sal de l-tartrato de pridopidina. |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| JP6887952B2 (ja) | 2015-02-25 | 2021-06-16 | プリレニア ニューロセラピューティクス リミテッド | 認知機能を改善するため、およびアルツハイマー病を治療するためのプリドピジンの使用 |
| AR105434A1 (es) | 2015-07-22 | 2017-10-04 | Teva Pharmaceuticals Int Gmbh | Proceso para preparar pridopidina |
| EP3324967A4 (en) | 2015-07-22 | 2019-03-20 | Prilenia Therapeutics Development Ltd. | PRIDOPIDINE-BASED FORMULATIONS AND USE OF THE SAME |
| EP4516356A3 (en) * | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
-
2015
- 2015-06-23 TW TW104120197A patent/TW201613859A/zh unknown
- 2015-06-26 UY UY0001036192A patent/UY36192A/es not_active Application Discontinuation
- 2015-06-29 JP JP2017520772A patent/JP6800842B2/ja active Active
- 2015-06-29 CN CN201580035520.9A patent/CN106456618A/zh active Pending
- 2015-06-29 EP EP15814023.6A patent/EP3160470B1/en active Active
- 2015-06-29 MX MX2016017332A patent/MX382649B/es unknown
- 2015-06-29 WO PCT/US2015/038349 patent/WO2016003919A1/en not_active Ceased
- 2015-06-29 PL PL15814023.6T patent/PL3160470T3/pl unknown
- 2015-06-29 BR BR112016030968-5A patent/BR112016030968B1/pt active IP Right Grant
- 2015-06-29 EA EA201790101A patent/EA201790101A1/ru unknown
- 2015-06-29 EP EP22165235.7A patent/EP4049998A1/en active Pending
- 2015-06-29 AU AU2015284385A patent/AU2015284385B2/en active Active
- 2015-06-29 HU HUE15814023A patent/HUE060242T2/hu unknown
- 2015-06-29 CN CN202110715595.9A patent/CN113511997A/zh active Pending
- 2015-06-29 US US14/754,339 patent/US10130621B2/en active Active
- 2015-06-29 CA CA2951494A patent/CA2951494C/en active Active
- 2015-06-29 DK DK15814023.6T patent/DK3160470T3/da active
- 2015-06-29 ES ES15814023T patent/ES2927888T3/es active Active
-
2016
- 2016-12-15 IL IL249601A patent/IL249601B/en active IP Right Grant
-
2018
- 2018-10-03 US US16/150,977 patent/US10406145B2/en active Active
-
2019
- 2019-08-08 US US16/535,107 patent/US11141412B2/en active Active
-
2020
- 2020-01-28 IL IL272306A patent/IL272306B/en active IP Right Grant
- 2020-04-24 JP JP2020077160A patent/JP7035108B2/ja active Active
-
2021
- 2021-10-11 US US17/498,075 patent/US20220023280A1/en active Pending
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