JP2017518348A - Ｉｒａｋ４阻害剤としての置換インダゾール化合物 - Google Patents

Ｉｒａｋ４阻害剤としての置換インダゾール化合物 Download PDF

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JP2017518348A
JP2017518348A JP2016574004A JP2016574004A JP2017518348A JP 2017518348 A JP2017518348 A JP 2017518348A JP 2016574004 A JP2016574004 A JP 2016574004A JP 2016574004 A JP2016574004 A JP 2016574004A JP 2017518348 A JP2017518348 A JP 2017518348A
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optionally substituted
mmol
disease
compound
methyl
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JP2017518348A5 (cg-RX-API-DMAC7.html
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ラオ ガマディ，ベンケイツワー
ラオ ガマディ，ベンケイツワー
サマジダール，スサンタ
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Aurigene Oncology Ltd
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Aurigene Discovery Technologies Ltd
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016574004A 2014-06-20 2015-06-19 Ｉｒａｋ４阻害剤としての置換インダゾール化合物 Pending JP2017518348A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3017CH2014 2014-06-20
IN3017/CHE/2014 2014-06-20
PCT/IB2015/054620 WO2015193846A1 (en) 2014-06-20 2015-06-19 Substituted indazole compounds as irak4 inhibitors

Publications (2)

Publication Number Publication Date
JP2017518348A true JP2017518348A (ja) 2017-07-06
JP2017518348A5 JP2017518348A5 (cg-RX-API-DMAC7.html) 2018-08-02

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US (1) US20170152263A1 (cg-RX-API-DMAC7.html)
EP (1) EP3157521A4 (cg-RX-API-DMAC7.html)
JP (1) JP2017518348A (cg-RX-API-DMAC7.html)
KR (1) KR20170016500A (cg-RX-API-DMAC7.html)
CN (1) CN106456609A (cg-RX-API-DMAC7.html)
AU (1) AU2015275730A1 (cg-RX-API-DMAC7.html)
BR (1) BR112016029853A2 (cg-RX-API-DMAC7.html)
CA (1) CA2952188A1 (cg-RX-API-DMAC7.html)
CU (1) CU20160188A7 (cg-RX-API-DMAC7.html)
EA (1) EA201692418A1 (cg-RX-API-DMAC7.html)
HK (1) HK1231411A1 (cg-RX-API-DMAC7.html)
IL (1) IL249345A0 (cg-RX-API-DMAC7.html)
MX (1) MX2016017147A (cg-RX-API-DMAC7.html)
PH (1) PH12016502382A1 (cg-RX-API-DMAC7.html)
SG (1) SG11201610009XA (cg-RX-API-DMAC7.html)
WO (1) WO2015193846A1 (cg-RX-API-DMAC7.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019503357A (ja) * 2015-12-22 2019-02-07 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ＩＲＡＫ４調節因子としてのピラゾロ［１，５ａ］ピリミジン誘導体
JP2024500247A (ja) * 2020-12-25 2024-01-05 メッドシャイン ディスカバリー インコーポレイテッド アミドオキサゾール系化合物
JP2025502802A (ja) * 2021-12-31 2025-01-28 アクロ バイオサイエンス （エイチケー） リミテッド Ｉｒａｋ４阻害剤としてのヘテロアリール化合物、その組成物および用途

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3805233T (pt) 2014-01-13 2024-04-15 Aurigene Oncology Ltd Enantiómeros (r) e (s) de n-(5-(3-hidroxipirrolidin-1-il)-2 morfolinooxazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)oxazole-carboxamida como inibidores de irak4 para o tratamento de cancro
JO3705B1 (ar) 2014-11-26 2021-01-31 Bayer Pharma AG إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
UY36660A (es) 2015-04-30 2016-11-30 Bayer Pharma AG Combinaciones de inhibidores de irak4
EP3195865A1 (de) 2016-01-25 2017-07-26 Bayer Pharma Aktiengesellschaft Kombinationen von irak4 inhibitoren und btk inhibitoren
HK1249509A1 (zh) * 2015-07-15 2018-11-02 Aurigene Discovery Technologies Limited 作为irak-4抑制剂的吲唑及氮杂吲唑化合物
US10435396B2 (en) 2016-03-03 2019-10-08 Bayer Pharma Aktiegesellschaft 2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs
CN119367364A (zh) 2016-06-01 2025-01-28 拜耳动物保健有限责任公司 用于治疗和预防动物的过敏性和/或炎症性疾病的取代吲唑
CA3025826A1 (en) * 2016-06-01 2017-12-07 Bayer Pharma Aktiengesellschaft Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases
WO2018049214A1 (en) 2016-09-09 2018-03-15 Incyte Corporation Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
EP3510032B1 (en) 2016-09-09 2022-07-06 Incyte Corporation Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
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