CA2952188A1 - Substituted indazole compounds as irak4 inhibitors - Google Patents
Substituted indazole compounds as irak4 inhibitors Download PDFInfo
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- CA2952188A1 CA2952188A1 CA2952188A CA2952188A CA2952188A1 CA 2952188 A1 CA2952188 A1 CA 2952188A1 CA 2952188 A CA2952188 A CA 2952188A CA 2952188 A CA2952188 A CA 2952188A CA 2952188 A1 CA2952188 A1 CA 2952188A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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| IN3017CH2014 | 2014-06-20 | ||
| IN3017/CHE/2014 | 2014-06-20 | ||
| PCT/IB2015/054620 WO2015193846A1 (en) | 2014-06-20 | 2015-06-19 | Substituted indazole compounds as irak4 inhibitors |
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| CA2952188A1 true CA2952188A1 (en) | 2015-12-23 |
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| PT3805233T (pt) | 2014-01-13 | 2024-04-15 | Aurigene Oncology Ltd | Enantiómeros (r) e (s) de n-(5-(3-hidroxipirrolidin-1-il)-2 morfolinooxazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)oxazole-carboxamida como inibidores de irak4 para o tratamento de cancro |
| JO3705B1 (ar) | 2014-11-26 | 2021-01-31 | Bayer Pharma AG | إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية |
| UY36660A (es) | 2015-04-30 | 2016-11-30 | Bayer Pharma AG | Combinaciones de inhibidores de irak4 |
| EP3195865A1 (de) | 2016-01-25 | 2017-07-26 | Bayer Pharma Aktiengesellschaft | Kombinationen von irak4 inhibitoren und btk inhibitoren |
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| CA3025826A1 (en) * | 2016-06-01 | 2017-12-07 | Bayer Pharma Aktiengesellschaft | Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases |
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| US11299473B2 (en) | 2018-04-13 | 2022-04-12 | Incyte Corporation | Benzimidazole and indole compounds and uses thereof |
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- 2015-06-19 HK HK17105243.5A patent/HK1231411A1/zh unknown
- 2015-06-19 SG SG11201610009XA patent/SG11201610009XA/en unknown
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- 2015-06-19 KR KR1020177001487A patent/KR20170016500A/ko not_active Withdrawn
- 2015-06-19 EA EA201692418A patent/EA201692418A1/ru unknown
- 2015-06-19 AU AU2015275730A patent/AU2015275730A1/en not_active Abandoned
- 2015-06-19 WO PCT/IB2015/054620 patent/WO2015193846A1/en not_active Ceased
- 2015-06-19 CU CUP2016000188A patent/CU20160188A7/es unknown
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2016
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| EP3157521A1 (en) | 2017-04-26 |
| AU2015275730A1 (en) | 2016-12-15 |
| WO2015193846A1 (en) | 2015-12-23 |
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| JP2017518348A (ja) | 2017-07-06 |
| EA201692418A1 (ru) | 2017-04-28 |
| IL249345A0 (en) | 2017-02-28 |
| CN106456609A (zh) | 2017-02-22 |
| SG11201610009XA (en) | 2017-01-27 |
| PH12016502382A1 (en) | 2017-02-20 |
| US20170152263A1 (en) | 2017-06-01 |
| BR112016029853A2 (pt) | 2017-08-22 |
| KR20170016500A (ko) | 2017-02-13 |
| MX2016017147A (es) | 2017-06-07 |
| CU20160188A7 (es) | 2017-06-05 |
| EP3157521A4 (en) | 2018-02-14 |
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