|
CH652145A5
(de)
|
1982-01-22 |
1985-10-31 |
Sandoz Ag |
Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
|
|
US4634666A
(en)
|
1984-01-06 |
1987-01-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Human-murine hybridoma fusion partner
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5859205A
(en)
*
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5194594A
(en)
|
1990-09-07 |
1993-03-16 |
Techniclone, Inc. |
Modified antibodies
|
|
DE69230142T2
(de)
|
1991-05-15 |
2000-03-09 |
Cambridge Antibody Technology Ltd. |
Verfahren zur herstellung von spezifischen bindungspaargliedern
|
|
US5858657A
(en)
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
CA2124967C
(en)
|
1991-12-17 |
2008-04-08 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
EP0672142B1
(en)
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
|
US5877218A
(en)
|
1994-01-10 |
1999-03-02 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
|
DE19539493A1
(de)
|
1995-10-24 |
1997-04-30 |
Thomae Gmbh Dr K |
Starker homologer Promotor aus Hamster
|
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
EP1005368B1
(en)
|
1997-03-10 |
2009-09-02 |
Ottawa Hospital Research Institute |
Use of nucleic acids containing unmethylated CpG dinucleotide in combination with alum as adjuvants
|
|
US5888809A
(en)
|
1997-05-01 |
1999-03-30 |
Icos Corporation |
Hamster EF-1α transcriptional regulatory DNA
|
|
AU757961B2
(en)
|
1998-09-30 |
2003-03-13 |
Sankyo Company Limited |
Anti-Fas antibodies
|
|
CA2361492A1
(en)
|
1999-02-05 |
2000-08-10 |
Samsung Electronics Co., Ltd. |
Image texture retrieving method and apparatus thereof
|
|
US20040220103A1
(en)
|
1999-04-19 |
2004-11-04 |
Immunex Corporation |
Soluble tumor necrosis factor receptor treatment of medical disorders
|
|
US7192931B2
(en)
|
2000-10-12 |
2007-03-20 |
Neuren Pharmaceuticals Ltd. |
Treatment of demyelinating diseases
|
|
AU2002252444A1
(en)
|
2001-03-23 |
2002-10-08 |
Board Of Regents, The University Of Texas System |
Methods for inhibition of angiogenesis, tumor growth and metastasis by fully human anti-il8 and anti-muc18 in diverse types of tumors
|
|
WO2004006955A1
(en)
|
2001-07-12 |
2004-01-22 |
Jefferson Foote |
Super humanized antibodies
|
|
TWI334439B
(en)
|
2001-08-01 |
2010-12-11 |
Centocor Inc |
Anti-tnf antibodies, compositions, methods and uses
|
|
JP2005514409A
(ja)
*
|
2001-12-28 |
2005-05-19 |
アブジェニックス・インコーポレーテッド |
Muc18抗原に対する抗体の使用
|
|
JP2005516965A
(ja)
|
2001-12-28 |
2005-06-09 |
アブジェニックス・インコーポレーテッド |
抗muc18抗体を使用する方法
|
|
EP1470146B8
(en)
|
2001-12-28 |
2007-09-12 |
Amgen Fremont Inc. |
Antibodies against the muc18 antigen
|
|
WO2003105782A2
(en)
*
|
2002-06-17 |
2003-12-24 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Specificity grafting of a murine antibody onto a human framework
|
|
EP1382615A1
(en)
*
|
2002-07-15 |
2004-01-21 |
Xerion Pharmaceuticals AG |
MCAM inhibitors
|
|
MXPA05005481A
(es)
|
2002-11-29 |
2005-07-25 |
Boehringer Ingelheim Pharma |
Nuevos genes de la fosfotransferasa de neomicina y procedimiento para la seleccion de celulas recombinantes de produccion elevada.
|
|
KR20050114212A
(ko)
|
2003-01-24 |
2005-12-05 |
엘란 파마슈티칼스, 인크. |
수초재생제의 투여에 의한 탈수초성 질환 및 마비의 치료및 조성물
|
|
DE10338531A1
(de)
|
2003-08-19 |
2005-04-07 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Reklonierung von Produktionszellen
|
|
WO2005123048A2
(en)
*
|
2004-06-21 |
2005-12-29 |
Proteome Sciences Plc |
Screening methods using c-abl, fyn and syk in combination with tau protein
|
|
JO3000B1
(ar)
*
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
PT1820022E
(pt)
|
2004-11-10 |
2009-08-05 |
Boehringer Ingelheim Pharma |
Utilização de análise por citometria de fluxo para optimizar estratégias de conservação de bancos de células cho
|
|
WO2007058725A2
(en)
|
2005-10-12 |
2007-05-24 |
The Regents Of The University Of California |
Engineered antibody fragment that irreversibly binds an antigen
|
|
US20080124760A1
(en)
|
2006-07-26 |
2008-05-29 |
Barbara Enenkel |
Regulatory Nucleic Acid Elements
|
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
|
WO2008107388A1
(en)
|
2007-03-02 |
2008-09-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Improvement of protein production
|
|
EP2031064A1
(de)
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Verfahren zur Steigerung von Proteintitern
|
|
WO2009028663A1
(ja)
|
2007-08-30 |
2009-03-05 |
Kyowa Hakko Kirin Co., Ltd. |
抗Claudin-3抗体
|
|
US20120047586A9
(en)
|
2007-10-24 |
2012-02-23 |
Otsuka Chemical Co., Ltd |
Polypeptide having enhanced effector function
|
|
CA2705292C
(en)
|
2007-11-13 |
2016-06-21 |
Teva Biopharmaceuticals Usa, Inc. |
Humanized antibodies against tl1a
|
|
NZ585516A
(en)
|
2007-12-21 |
2012-07-27 |
Hoffmann La Roche |
Anti-cd20 antibody formulation
|
|
AR070141A1
(es)
|
2008-01-23 |
2010-03-17 |
Glenmark Pharmaceuticals Sa |
Anticuerpos humanizados especificos para el factor von willebrand
|
|
US8293468B2
(en)
|
2009-06-10 |
2012-10-23 |
Centre Hospitalier De L'université De Montréal |
MCAM modulation and uses thereof
|
|
WO2011100477A2
(en)
|
2010-02-10 |
2011-08-18 |
Taiga Biotechnologies, Inc. |
Antibodies and processes for preparing the same
|
|
SG10201501562VA
(en)
|
2010-03-02 |
2015-04-29 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
|
US9062101B2
(en)
|
2010-08-14 |
2015-06-23 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
|
EP2718327A1
(en)
*
|
2011-06-06 |
2014-04-16 |
Neotope Biosciences Limited |
Mcam antagonists and methods of treatment
|
|
NZ629204A
(en)
|
2012-02-16 |
2016-09-30 |
Santarus Inc |
Anti-vla1 (cd49a) antibody pharmaceutical compositions
|
|
US20140004131A1
(en)
|
2012-05-04 |
2014-01-02 |
Novartis Ag |
Antibody formulation
|
|
US9216219B2
(en)
|
2012-06-12 |
2015-12-22 |
Novartis Ag |
Anti-BAFFR antibody formulation
|
|
TWI660972B
(zh)
|
2012-09-10 |
2019-06-01 |
愛爾蘭商尼歐托普生物科學公司 |
抗mcam抗體及相關使用方法
|
|
EP3892288A1
(en)
|
2013-10-24 |
2021-10-13 |
Astrazeneca AB |
Stable, aqueous antibody formulations
|
|
WO2015136570A1
(ja)
|
2014-03-11 |
2015-09-17 |
パナソニック液晶ディスプレイ株式会社 |
表示装置及びその駆動方法
|
|
TW201623331A
(zh)
|
2014-03-12 |
2016-07-01 |
普羅帝納生物科學公司 |
抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法
|
|
ES2744526T3
(es)
|
2014-03-12 |
2020-02-25 |
Prothena Biosciences Ltd |
Anticuerpos anti-MCAM y métodos de uso asociados
|
|
US20170101470A1
(en)
|
2014-03-12 |
2017-04-13 |
Prothena Biosciences Limited |
Use of Anti-MCAM Antibodies for Treatment or Prophylaxis of Giant Cell Arteritis, Polymyalgia Rheumatica or Takayasus Arteritis
|
|
US20170129954A1
(en)
|
2014-03-12 |
2017-05-11 |
Prothena Biosciences Limited |
Use of Anti-MCAM Antibodies for Treatment or Prophylaxis of Giant Cell Arteritis, Polymyalgia Rheumatica or Takayasus Arteritis
|
|
CA2938933A1
(en)
|
2014-03-12 |
2015-09-17 |
Prothena Biosciences Limited |
Anti-laminin4 antibodies specific for lg4-5
|
|
KR20160131082A
(ko)
|
2014-03-12 |
2016-11-15 |
프로테나 바이오사이언시즈 리미티드 |
Lg1-3에 특이적인 항-라미닌4 항체
|
|
KR20170052526A
(ko)
|
2014-03-13 |
2017-05-12 |
프로테나 바이오사이언시즈 리미티드 |
다발성 경화증에 대한 병용 치료
|
|
WO2017046774A2
(en)
|
2015-09-16 |
2017-03-23 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
|
|
WO2017046776A2
(en)
|
2015-09-16 |
2017-03-23 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
|
|
WO2017149513A1
(en)
|
2016-03-03 |
2017-09-08 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|
|
WO2017208210A1
(en)
|
2016-06-03 |
2017-12-07 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|
|
WO2018223140A1
(en)
|
2017-06-02 |
2018-12-06 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|