WO2007058725A2 - Engineered antibody fragment that irreversibly binds an antigen - Google Patents

Engineered antibody fragment that irreversibly binds an antigen Download PDF

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Publication number
WO2007058725A2
WO2007058725A2 PCT/US2006/040131 US2006040131W WO2007058725A2 WO 2007058725 A2 WO2007058725 A2 WO 2007058725A2 US 2006040131 W US2006040131 W US 2006040131W WO 2007058725 A2 WO2007058725 A2 WO 2007058725A2
Authority
WO
WIPO (PCT)
Prior art keywords
antibody
mutant
sequence
binding
exemplary embodiment
Prior art date
Application number
PCT/US2006/040131
Other languages
French (fr)
Other versions
WO2007058725A3 (en
Inventor
Claude F. Meares
Nathaniel G. Butlin
Mark R. Mccoy
Todd M. Corneillie
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US72650405P priority Critical
Priority to US60/726,504 priority
Priority to US75059105P priority
Priority to US60/750,591 priority
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2007058725A2 publication Critical patent/WO2007058725A2/en
Publication of WO2007058725A3 publication Critical patent/WO2007058725A3/en

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