JP2017517569A - アッカーマンシア・ムシニフィラ菌に由来する細胞外小胞を有効成分として含有する代謝疾患の治療または予防用の組成物 - Google Patents
アッカーマンシア・ムシニフィラ菌に由来する細胞外小胞を有効成分として含有する代謝疾患の治療または予防用の組成物 Download PDFInfo
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Abstract
Description
Claims (11)
- アッカーマンシア・ムシニフィラ(Akkermansia muciniphila)菌に由来する細胞外小胞を有効成分として含有する、代謝疾患の治療または予防用の薬学組成物。
- 上記の細胞外小胞はアッカーマンシア・ムシニフィラ(Akkermansia muciniphila)菌で自然的または人工的に分泌されるものを特徴とする、請求項1に記載の代謝疾患の治療または予防用の薬学組成物。
- 上記の細胞外小胞は平均直径が20〜300nmであることを特徴とする、請求項1に記載の代謝疾患の治療または予防用の薬学組成物。
- 上記の代謝疾患は、肥満、糖尿病、高脂血症、動脈硬化症および高血圧からなる群より選ばれることを特徴とする、請求項1に記載の代謝疾患の治療または予防用の薬学組成物。
- アッカーマンシア・ムシニフィラ(Akkermansia muciniphila)菌に由来する細胞外小胞を含有する、代謝疾患の予防または改善用の食品組成物。
- 上記の細胞外小胞はアッカーマンシア・ムシニフィラ(Akkermansia muciniphila)菌で自然的または人工的に分泌されることを特徴とする、請求項5に記載の代謝疾患の予防または改善用の食品組成物。
- 上記の細胞外小胞は平均直径20〜300nmであることを特徴とする、請求項5に記載の代謝疾患の予防または改善用の食品組成物。
- 上記の代謝疾患は、肥満、糖尿病、高脂血症、動脈硬化症および高血圧からなる群より選ばれることを特徴とする、請求項5に記載の代謝疾患の予防または改善用の食品組成物。
- 上記の食品は、アッカーマンシア・ムシニフィラ(Akkermansia muciniphila)菌を添加して発酵させた発酵食品であることを特徴とする、請求項5に記載の代謝疾患の予防または改善用の食品組成物。
- 請求項1の組成物を個体に投与する段階を含む代謝疾患の治療方法。
- 代謝疾患の治療用途の請求項1の組成物。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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KR10-2014-0060409 | 2014-05-20 | ||
KR20140060409 | 2014-05-20 | ||
KR1020150068864A KR101740893B1 (ko) | 2014-05-20 | 2015-05-18 | Akkermansia muciniphila 균에서 유래하는 세포밖 소포를 유효성분으로 함유하는 대사질환의 치료 또는 예방용 조성물 |
KR10-2015-0068864 | 2015-05-18 | ||
PCT/KR2015/004983 WO2015178653A1 (ko) | 2014-05-20 | 2015-05-19 | Akkermansia muciniphila 균에서 유래하는 세포밖 소포를 유효성분으로 함유하는 대사질환의 치료 또는 예방용 조성물 |
Publications (2)
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JP2017517569A true JP2017517569A (ja) | 2017-06-29 |
JP6316501B2 JP6316501B2 (ja) | 2018-04-25 |
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JP2017514237A Active JP6316501B2 (ja) | 2014-05-20 | 2015-05-19 | アッカーマンシア・ムシニフィラ菌に由来する細胞外小胞を有効成分として含有する代謝疾患の治療または予防用の組成物 |
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US (2) | US20170087195A1 (ja) |
EP (1) | EP3165227B2 (ja) |
JP (1) | JP6316501B2 (ja) |
KR (1) | KR101740893B1 (ja) |
CN (1) | CN106535907A (ja) |
AU (1) | AU2015262214B2 (ja) |
CA (1) | CA2949644C (ja) |
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JP2020513799A (ja) * | 2018-02-21 | 2020-05-21 | エムディー ヘルスケア インコーポレイテッドMd Healthcare Inc. | クプリアウィドゥス属細菌由来のナノ小胞及びその使用 |
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Cited By (11)
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JP2019535231A (ja) * | 2016-07-08 | 2019-12-12 | エムディー ヘルスケア インコーポレイテッドMd Healthcare Inc. | プロピオニバクテリウム属細菌由来ナノ小胞およびその用途 |
JP2019528688A (ja) * | 2016-08-12 | 2019-10-17 | エムディー ヘルスケア インコーポレイテッドMd Healthcare Inc. | バチルス属細菌由来ナノ小胞およびその用途 |
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JP2020513799A (ja) * | 2018-02-21 | 2020-05-21 | エムディー ヘルスケア インコーポレイテッドMd Healthcare Inc. | クプリアウィドゥス属細菌由来のナノ小胞及びその使用 |
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JP2022502067A (ja) * | 2018-10-11 | 2022-01-11 | コバイオラブス,インコーポレーテッド | アッカーマンシアムシニフィラ菌株およびその用途 |
JP7185036B2 (ja) | 2018-10-11 | 2022-12-06 | コバイオラブス,インコーポレーテッド | アッカーマンシアムシニフィラ菌株およびその用途 |
JP2021052753A (ja) * | 2019-10-01 | 2021-04-08 | ヘルスバイオミーHealthbiome | 健康な妊産婦の母乳由来嫌気性ヒト菌株及びそれを用いた代謝性疾患の予防又は治療方法 |
WO2023224117A1 (ja) * | 2022-05-20 | 2023-11-23 | 大塚製薬株式会社 | アッカーマンシア属に属する微生物 |
WO2024048449A1 (ja) * | 2022-08-29 | 2024-03-07 | 株式会社ヤクルト本社 | 腸内細菌を有効成分とする抗肥満剤およびその作製方法 |
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KR20150133646A (ko) | 2015-11-30 |
CA2949644A1 (en) | 2015-11-26 |
US20170087195A1 (en) | 2017-03-30 |
EP3165227A4 (en) | 2017-10-25 |
AU2015262214B2 (en) | 2017-12-21 |
US11291694B2 (en) | 2022-04-05 |
EP3165227B2 (en) | 2021-10-27 |
CA2949644C (en) | 2019-01-15 |
CN106535907A (zh) | 2017-03-22 |
KR101740893B1 (ko) | 2017-06-13 |
AU2015262214A1 (en) | 2016-11-10 |
EP3165227A1 (en) | 2017-05-10 |
EP3165227B1 (en) | 2019-03-13 |
JP6316501B2 (ja) | 2018-04-25 |
US20200222470A1 (en) | 2020-07-16 |
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