JP2017517533A5 - - Google Patents

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Publication number
JP2017517533A5
JP2017517533A5 JP2016572258A JP2016572258A JP2017517533A5 JP 2017517533 A5 JP2017517533 A5 JP 2017517533A5 JP 2016572258 A JP2016572258 A JP 2016572258A JP 2016572258 A JP2016572258 A JP 2016572258A JP 2017517533 A5 JP2017517533 A5 JP 2017517533A5
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JP
Japan
Prior art keywords
composition
phosphatidylethanolamine
mol
peg
phosphatidylcholine
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Application number
JP2016572258A
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English (en)
Japanese (ja)
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JP6594909B2 (ja
JP2017517533A (ja
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Priority claimed from PCT/US2015/035681 external-priority patent/WO2015192093A1/en
Publication of JP2017517533A publication Critical patent/JP2017517533A/ja
Publication of JP2017517533A5 publication Critical patent/JP2017517533A5/ja
Application granted granted Critical
Publication of JP6594909B2 publication Critical patent/JP6594909B2/ja
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JP2016572258A 2014-06-12 2015-06-12 リン脂質組成物、その凍結乾燥方法および凍結乾燥物 Active JP6594909B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462011469P 2014-06-12 2014-06-12
US62/011,469 2014-06-12
PCT/US2015/035681 WO2015192093A1 (en) 2014-06-12 2015-06-12 Phospholipid composition and microbubbles and emulsions formed using same

Publications (3)

Publication Number Publication Date
JP2017517533A JP2017517533A (ja) 2017-06-29
JP2017517533A5 true JP2017517533A5 (enExample) 2018-07-12
JP6594909B2 JP6594909B2 (ja) 2019-10-23

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ID=54834464

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016572258A Active JP6594909B2 (ja) 2014-06-12 2015-06-12 リン脂質組成物、その凍結乾燥方法および凍結乾燥物

Country Status (8)

Country Link
US (3) US9801959B2 (enExample)
EP (1) EP3154591B1 (enExample)
JP (1) JP6594909B2 (enExample)
KR (1) KR102379534B1 (enExample)
CN (1) CN107106692B (enExample)
AU (1) AU2015274259B2 (enExample)
CA (1) CA2951922C (enExample)
WO (1) WO2015192093A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015374286B2 (en) 2014-12-31 2021-11-18 Lantheus Medical Imaging, Inc. Lipid-encapsulated gas microsphere compositions and related methods
IL260206B2 (en) * 2015-12-21 2023-04-01 Nuvox Pharma Llc Preparations containing a nanoemulsion of fluorocarbons and methods for their preparation
US20190117800A1 (en) * 2016-04-19 2019-04-25 Microvascuar Therapeutics Llc Systems and methods for filling vials with gases
IL262647B2 (en) 2016-05-04 2023-03-01 Lantheus Medical Imaging Inc Methods and devices for preparing sharpness factors for ultrasound
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
EP3530266A1 (en) 2018-02-27 2019-08-28 LipoCoat B.V. A lipid-based coating composition, and an object having a lipid-based coating
AU2019243579B2 (en) * 2018-03-29 2024-05-09 Microvascular Therapeutics LLC Compositions and methods of detecting and treating Alzheimer's disease
WO2019191557A1 (en) * 2018-03-29 2019-10-03 Case Wester Reserve University Stabilized nanobubbles and microbubbles for diagnostic and therapeutic applications
US20200360289A1 (en) 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension
US11717570B2 (en) 2019-05-15 2023-08-08 Bracco Suisse Sa Gas-filled microvesicles
GB201908352D0 (en) * 2019-06-11 2019-07-24 Innovation Ulster Ltd Sonodynamic therapy
WO2021096951A1 (en) * 2019-11-11 2021-05-20 Washington University Liposome compositions and methods of treatment targeted to tumor endothelium
CN111729094B (zh) * 2020-07-23 2021-07-02 四川大学华西医院 类磷脂两亲性嵌段共聚物基超声造影剂及其制备方法
CN116897055A (zh) * 2020-12-27 2023-10-17 索尔斯蒂斯制药有限公司 用于混合旨在用于体内使用的磷脂组合物的筒
NL2027237B1 (en) * 2020-12-27 2022-07-21 Solstice Pharmaceuticals B V Process for controlled manufacturing of mono-disperse microbubbles
US20240299653A1 (en) 2020-12-27 2024-09-12 Solstice Pharmaceuticals B.V. A Cartridge for Mixing a Liquid Intended for Intracorporeal Use
US20250195698A1 (en) * 2022-02-09 2025-06-19 Lantheus Medical Imaging, Inc. Gas nano/micro-bubble compositions and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733572A (en) * 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
HUP9900879A2 (hu) * 1995-06-07 1999-08-30 Alliance Pharmaceutical Corp. Fordított fluor-szénhidrogén emulziós készítmények gyógyszeradagoláshoz
DE69718519T2 (de) * 1996-09-11 2003-11-06 Imarx Pharmaceutical Corp., Tucson Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US6572840B1 (en) * 1999-07-28 2003-06-03 Bristol-Myers Squibb Pharma Company Stable microbubbles comprised of a perfluoropropane encapsulated lipid moiety for use as an ultrasound contrast agent
US7357937B2 (en) * 2002-09-24 2008-04-15 Therox, Inc. Perfluorocarbon emulsions with non-fluorinated surfactants
US20050025710A1 (en) * 2003-07-29 2005-02-03 Michel Schneider Reconstitutable formulation and aqueous suspension of gas-filled microvesicles for diagnostic imaging
CN101389273B (zh) * 2004-08-05 2012-09-05 贝勒研究院 基因或药物递送系统
EP2253308A1 (en) * 2009-05-22 2010-11-24 Ludwig-Maximilians-Universität München Pharmaceutical composition comprising microbubbles for targeted tumor therapy
US10279053B2 (en) 2011-07-19 2019-05-07 Nuvox Pharma Llc Microbubble compositions, method of making same, and method using same

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