JP2017517533A5 - - Google Patents

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Publication number
JP2017517533A5
JP2017517533A5 JP2016572258A JP2016572258A JP2017517533A5 JP 2017517533 A5 JP2017517533 A5 JP 2017517533A5 JP 2016572258 A JP2016572258 A JP 2016572258A JP 2016572258 A JP2016572258 A JP 2016572258A JP 2017517533 A5 JP2017517533 A5 JP 2017517533A5
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JP
Japan
Prior art keywords
composition
phosphatidylethanolamine
mol
peg
phosphatidylcholine
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Application number
JP2016572258A
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English (en)
Japanese (ja)
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JP6594909B2 (ja
JP2017517533A (ja
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Priority claimed from PCT/US2015/035681 external-priority patent/WO2015192093A1/en
Publication of JP2017517533A publication Critical patent/JP2017517533A/ja
Publication of JP2017517533A5 publication Critical patent/JP2017517533A5/ja
Application granted granted Critical
Publication of JP6594909B2 publication Critical patent/JP6594909B2/ja
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JP2016572258A 2014-06-12 2015-06-12 リン脂質組成物、その凍結乾燥方法および凍結乾燥物 Active JP6594909B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462011469P 2014-06-12 2014-06-12
US62/011,469 2014-06-12
PCT/US2015/035681 WO2015192093A1 (en) 2014-06-12 2015-06-12 Phospholipid composition and microbubbles and emulsions formed using same

Publications (3)

Publication Number Publication Date
JP2017517533A JP2017517533A (ja) 2017-06-29
JP2017517533A5 true JP2017517533A5 (enExample) 2018-07-12
JP6594909B2 JP6594909B2 (ja) 2019-10-23

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ID=54834464

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016572258A Active JP6594909B2 (ja) 2014-06-12 2015-06-12 リン脂質組成物、その凍結乾燥方法および凍結乾燥物

Country Status (8)

Country Link
US (3) US9801959B2 (enExample)
EP (1) EP3154591B1 (enExample)
JP (1) JP6594909B2 (enExample)
KR (1) KR102379534B1 (enExample)
CN (1) CN107106692B (enExample)
AU (1) AU2015274259B2 (enExample)
CA (1) CA2951922C (enExample)
WO (1) WO2015192093A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL296875A (en) 2014-12-31 2022-12-01 Lantheus Medical Imaging Inc Fat-wrapped gas microsphere preparations and related methods
IL260206B2 (en) 2015-12-21 2023-04-01 Nuvox Pharma Llc Preparations containing a nanoemulsion of fluorocarbons and methods for their preparation
WO2017184672A1 (en) * 2016-04-19 2017-10-26 Microvascuar Therapeutics Llc Systems and methods for filling vials with gases
CA3022698A1 (en) 2016-05-04 2017-11-09 Lantheus Medical Imaging, Inc. Methods and devices for preparation of ultrasound contrast agents
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
EP3530266A1 (en) * 2018-02-27 2019-08-28 LipoCoat B.V. A lipid-based coating composition, and an object having a lipid-based coating
WO2019191557A1 (en) * 2018-03-29 2019-10-03 Case Wester Reserve University Stabilized nanobubbles and microbubbles for diagnostic and therapeutic applications
CN116173238A (zh) * 2018-03-29 2023-05-30 微脉管治疗有限公司 用于检测和治疗阿尔茨海默病的组合物及方法
US11717570B2 (en) 2019-05-15 2023-08-08 Bracco Suisse Sa Gas-filled microvesicles
US20200360289A1 (en) 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension
GB201908352D0 (en) * 2019-06-11 2019-07-24 Innovation Ulster Ltd Sonodynamic therapy
US20220387460A1 (en) * 2019-11-11 2022-12-08 Washington University Liposome compositions and methods of treatment targeted to tumor endothelium
CN111729094B (zh) * 2020-07-23 2021-07-02 四川大学华西医院 类磷脂两亲性嵌段共聚物基超声造影剂及其制备方法
NL2027237B1 (en) * 2020-12-27 2022-07-21 Solstice Pharmaceuticals B V Process for controlled manufacturing of mono-disperse microbubbles
CN116897055A (zh) * 2020-12-27 2023-10-17 索尔斯蒂斯制药有限公司 用于混合旨在用于体内使用的磷脂组合物的筒
WO2022139583A1 (en) 2020-12-27 2022-06-30 Solstice Pharmaceuticals B.V. A cartridge for mixing a phospholipid composition intended for intracorporeal use
AU2023217725A1 (en) * 2022-02-09 2024-08-15 Lantheus Medical Imaging, Inc. Gas nano/micro-bubble compositions and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733572A (en) * 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
CN1195981A (zh) * 1995-06-07 1998-10-14 联合药品公司 药物输送用的反相碳氟化合物乳液组合物
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
PT977597E (pt) * 1996-09-11 2003-06-30 Imarx Pharmaceutical Corp Metodos melhorados para imagiologia de diagnosticoutilizando um agente de contraste e um vasodil atador
US6572840B1 (en) 1999-07-28 2003-06-03 Bristol-Myers Squibb Pharma Company Stable microbubbles comprised of a perfluoropropane encapsulated lipid moiety for use as an ultrasound contrast agent
US7357937B2 (en) * 2002-09-24 2008-04-15 Therox, Inc. Perfluorocarbon emulsions with non-fluorinated surfactants
US20050025710A1 (en) * 2003-07-29 2005-02-03 Michel Schneider Reconstitutable formulation and aqueous suspension of gas-filled microvesicles for diagnostic imaging
CN101389273B (zh) * 2004-08-05 2012-09-05 贝勒研究院 基因或药物递送系统
EP2253308A1 (en) * 2009-05-22 2010-11-24 Ludwig-Maximilians-Universität München Pharmaceutical composition comprising microbubbles for targeted tumor therapy
US10279053B2 (en) * 2011-07-19 2019-05-07 Nuvox Pharma Llc Microbubble compositions, method of making same, and method using same

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