JP2017517533A5 - - Google Patents
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- Publication number
- JP2017517533A5 JP2017517533A5 JP2016572258A JP2016572258A JP2017517533A5 JP 2017517533 A5 JP2017517533 A5 JP 2017517533A5 JP 2016572258 A JP2016572258 A JP 2016572258A JP 2016572258 A JP2016572258 A JP 2016572258A JP 2017517533 A5 JP2017517533 A5 JP 2017517533A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- phosphatidylethanolamine
- mol
- peg
- phosphatidylcholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462011469P | 2014-06-12 | 2014-06-12 | |
| US62/011,469 | 2014-06-12 | ||
| PCT/US2015/035681 WO2015192093A1 (en) | 2014-06-12 | 2015-06-12 | Phospholipid composition and microbubbles and emulsions formed using same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017517533A JP2017517533A (ja) | 2017-06-29 |
| JP2017517533A5 true JP2017517533A5 (enExample) | 2018-07-12 |
| JP6594909B2 JP6594909B2 (ja) | 2019-10-23 |
Family
ID=54834464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016572258A Active JP6594909B2 (ja) | 2014-06-12 | 2015-06-12 | リン脂質組成物、その凍結乾燥方法および凍結乾燥物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US9801959B2 (enExample) |
| EP (1) | EP3154591B1 (enExample) |
| JP (1) | JP6594909B2 (enExample) |
| KR (1) | KR102379534B1 (enExample) |
| CN (1) | CN107106692B (enExample) |
| AU (1) | AU2015274259B2 (enExample) |
| CA (1) | CA2951922C (enExample) |
| WO (1) | WO2015192093A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4154915A1 (en) | 2014-12-31 | 2023-03-29 | Lantheus Medical Imaging, Inc. | Lipid-encapsulated gas microsphere compositions and related methods |
| JP6936226B2 (ja) * | 2015-12-21 | 2021-09-15 | ヌヴォックス ファーマ エル．エル．シー．Ｎｕｖｏｘ Ｐｈａｒｍａ Ｌ．Ｌ．Ｃ． | フルオロカーボンナノエマルジョンの組成物 |
| WO2017184672A1 (en) * | 2016-04-19 | 2017-10-26 | Microvascuar Therapeutics Llc | Systems and methods for filling vials with gases |
| KR20180133527A (ko) | 2016-05-04 | 2018-12-14 | 랜티우스 메디컬 이메징, 인크. | 초음파 조영제의 제조 방법 및 장치 |
| US9789210B1 (en) | 2016-07-06 | 2017-10-17 | Lantheus Medical Imaging, Inc. | Methods for making ultrasound contrast agents |
| EP3530266A1 (en) | 2018-02-27 | 2019-08-28 | LipoCoat B.V. | A lipid-based coating composition, and an object having a lipid-based coating |
| EP3773752A4 (en) * | 2018-03-29 | 2022-01-12 | Case Western Reserve University | Stabilized nanobubbles and microbubbles for diagnostic and therapeutic applications |
| CN116173238A (zh) * | 2018-03-29 | 2023-05-30 | 微脉管治疗有限公司 | 用于检测和治疗阿尔茨海默病的组合物及方法 |
| US11717570B2 (en) | 2019-05-15 | 2023-08-08 | Bracco Suisse Sa | Gas-filled microvesicles |
| US20200360289A1 (en) | 2019-05-15 | 2020-11-19 | Bracco Suisse Sa | Freeze-dried product and gas-filled microvesicles suspension |
| GB201908352D0 (en) * | 2019-06-11 | 2019-07-24 | Innovation Ulster Ltd | Sonodynamic therapy |
| US20220387460A1 (en) * | 2019-11-11 | 2022-12-08 | Washington University | Liposome compositions and methods of treatment targeted to tumor endothelium |
| CN111729094B (zh) * | 2020-07-23 | 2021-07-02 | 四川大学华西医院 | 类磷脂两亲性嵌段共聚物基超声造影剂及其制备方法 |
| CN116897055A (zh) * | 2020-12-27 | 2023-10-17 | 索尔斯蒂斯制药有限公司 | 用于混合旨在用于体内使用的磷脂组合物的筒 |
| JP2024501982A (ja) * | 2020-12-27 | 2024-01-17 | ソルスティス ファーマシューティカルズ ビー．ブイ． | 体内使用を意図したリン脂質組成物を混合するためのカートリッジ |
| NL2027237B1 (en) | 2020-12-27 | 2022-07-21 | Solstice Pharmaceuticals B V | Process for controlled manufacturing of mono-disperse microbubbles |
| TW202342111A (zh) * | 2022-02-09 | 2023-11-01 | 美商藍瑟斯醫學影像公司 | 氣體奈米/微泡組合物及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5733572A (en) * | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
| US7083572B2 (en) * | 1993-11-30 | 2006-08-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Therapeutic delivery systems |
| PL323931A1 (en) * | 1995-06-07 | 1998-04-27 | Alliance Pharma | Compositions of reversed emulsion of fluorine derivatives of hydrocarbons for use as drug delivering carriers |
| ES2289188T3 (es) * | 1996-09-11 | 2008-02-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Procedimiento para la obtencion de imagenes para el diagnostico usando un agente de contraste y un vasodilatador. |
| US5846517A (en) * | 1996-09-11 | 1998-12-08 | Imarx Pharmaceutical Corp. | Methods for diagnostic imaging using a renal contrast agent and a vasodilator |
| US6572840B1 (en) * | 1999-07-28 | 2003-06-03 | Bristol-Myers Squibb Pharma Company | Stable microbubbles comprised of a perfluoropropane encapsulated lipid moiety for use as an ultrasound contrast agent |
| US7357937B2 (en) * | 2002-09-24 | 2008-04-15 | Therox, Inc. | Perfluorocarbon emulsions with non-fluorinated surfactants |
| US20050025710A1 (en) * | 2003-07-29 | 2005-02-03 | Michel Schneider | Reconstitutable formulation and aqueous suspension of gas-filled microvesicles for diagnostic imaging |
| CN101389273B (zh) | 2004-08-05 | 2012-09-05 | 贝勒研究院 | 基因或药物递送系统 |
| EP2253308A1 (en) | 2009-05-22 | 2010-11-24 | Ludwig-Maximilians-Universität München | Pharmaceutical composition comprising microbubbles for targeted tumor therapy |
| US10279053B2 (en) * | 2011-07-19 | 2019-05-07 | Nuvox Pharma Llc | Microbubble compositions, method of making same, and method using same |
-
2015
- 2015-06-12 CN CN201580038940.2A patent/CN107106692B/zh active Active
- 2015-06-12 JP JP2016572258A patent/JP6594909B2/ja active Active
- 2015-06-12 EP EP15806338.8A patent/EP3154591B1/en active Active
- 2015-06-12 CA CA2951922A patent/CA2951922C/en active Active
- 2015-06-12 KR KR1020177000514A patent/KR102379534B1/ko active Active
- 2015-06-12 US US14/738,702 patent/US9801959B2/en active Active
- 2015-06-12 WO PCT/US2015/035681 patent/WO2015192093A1/en not_active Ceased
- 2015-06-12 AU AU2015274259A patent/AU2015274259B2/en active Active
-
2017
- 2017-08-17 US US15/679,738 patent/US10493173B2/en active Active
-
2019
- 2019-01-26 US US16/258,581 patent/US11160885B2/en active Active
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