JP2020532546A5 - - Google Patents
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- JP2020532546A5 JP2020532546A5 JP2020512589A JP2020512589A JP2020532546A5 JP 2020532546 A5 JP2020532546 A5 JP 2020532546A5 JP 2020512589 A JP2020512589 A JP 2020512589A JP 2020512589 A JP2020512589 A JP 2020512589A JP 2020532546 A5 JP2020532546 A5 JP 2020532546A5
- Authority
- JP
- Japan
- Prior art keywords
- lipid
- composition
- molar ratio
- cationic lipid
- approximately
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023115742A JP2023138526A (ja) | 2017-08-31 | 2023-07-14 | 組織特異的送達用のカチオン性脂質組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762552783P | 2017-08-31 | 2017-08-31 | |
| US62/552,783 | 2017-08-31 | ||
| PCT/US2018/042555 WO2019045897A1 (en) | 2017-08-31 | 2018-07-17 | CATIONIC LIPIDIC COMPOSITIONS FOR TISSUE-SPECIFIC ADMINISTRATION |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023115742A Division JP2023138526A (ja) | 2017-08-31 | 2023-07-14 | 組織特異的送達用のカチオン性脂質組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020532546A JP2020532546A (ja) | 2020-11-12 |
| JP2020532546A5 true JP2020532546A5 (enExample) | 2022-12-09 |
| JP7379325B2 JP7379325B2 (ja) | 2023-11-14 |
Family
ID=63104088
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020512589A Active JP7379325B2 (ja) | 2017-08-31 | 2018-07-17 | 組織特異的送達用のカチオン性脂質組成物 |
| JP2023115742A Pending JP2023138526A (ja) | 2017-08-31 | 2023-07-14 | 組織特異的送達用のカチオン性脂質組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023115742A Pending JP2023138526A (ja) | 2017-08-31 | 2023-07-14 | 組織特異的送達用のカチオン性脂質組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20190060482A1 (enExample) |
| EP (1) | EP3675826B1 (enExample) |
| JP (2) | JP7379325B2 (enExample) |
| CN (1) | CN111065377A (enExample) |
| AU (1) | AU2018324345B2 (enExample) |
| CA (1) | CA3073851A1 (enExample) |
| LT (1) | LT3675826T (enExample) |
| WO (1) | WO2019045897A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11690921B2 (en) * | 2018-05-18 | 2023-07-04 | Sangamo Therapeutics, Inc. | Delivery of target specific nucleases |
| PL4223886T3 (pl) | 2019-04-16 | 2025-03-31 | Genfit | Kompozycje i sposoby stabilizacji mikro-rna |
| CA3145425A1 (en) * | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| EP3865122A1 (en) * | 2020-02-11 | 2021-08-18 | Pantherna Therapeutics GmbH | Lipid composition and use thereof for delivery of a therapeutically active agent to endothelium |
| CN119604312A (zh) | 2022-06-30 | 2025-03-11 | 生命技术公司 | 用于体内递送的脂质组合物 |
| EP4642434A2 (en) | 2022-12-29 | 2025-11-05 | Life Technologies Corporation | Lipid compositions on the basis of ionizable lipids, use for delivery to immune cells |
| CN119997938A (zh) * | 2023-06-05 | 2025-05-13 | 安徽医科大学第一附属医院 | 肺靶向纳米胶束、制备方法及应用 |
| TW202543585A (zh) | 2024-03-08 | 2025-11-16 | 美商健臻公司 | 脂質奈米粒子 |
| WO2026030375A2 (en) | 2024-07-30 | 2026-02-05 | Genzyme Corporation | Lipid nanoparticles and methods of manufacture and use thereof |
| CN118576568B (zh) * | 2024-08-06 | 2024-11-26 | 北京悦康科创医药科技股份有限公司 | 一种药物组合物及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US6028077A (en) | 1997-04-15 | 2000-02-22 | Rinehart; Kenneth L. | Crambescidin compounds |
| NZ512244A (en) | 1998-11-12 | 2003-12-19 | Invitrogen Corp | Polycationic transfection reagents for introducing anions into a cell |
| EP1341497A4 (en) | 2000-11-02 | 2005-10-19 | Smithkline Beecham Corp | RECEPTOR ANTAGONIST LIPID CONJUGATES AND DISPOSABLE SUPPLEMENTS CONTAINING THEM |
| WO2003053408A1 (en) | 2001-12-19 | 2003-07-03 | Alza Corporation | Liposomal tumor necrosis factor compositions |
| JP4764426B2 (ja) | 2004-06-07 | 2011-09-07 | プロチバ バイオセラピューティクス インコーポレイティッド | カチオン性脂質および使用方法 |
| US20130189364A1 (en) | 2004-07-09 | 2013-07-25 | Robert Sabin | Compositions and methods of potentiating adjuvant pharmaceuticals targeting latent viral infections |
| GB0418172D0 (en) | 2004-08-13 | 2004-09-15 | Ic Vec Ltd | Vector |
| WO2009111088A2 (en) * | 2008-01-02 | 2009-09-11 | The Johns Hopkins University | Antitumor immunization by liposomal delivery of vaccine to the spleen |
| AP2015008874A0 (en) * | 2009-08-14 | 2015-11-30 | Alnylam Pharmaceuticals Inc | Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus |
| CA3009891C (en) * | 2009-12-23 | 2020-09-15 | Novartis Ag | Lipids, lipid compositions, and methods of using them |
| CN103380113B (zh) * | 2010-11-15 | 2018-03-30 | 生命科技公司 | 含胺的转染试剂及其制备和使用方法 |
| RU2013154295A (ru) * | 2011-06-08 | 2015-07-20 | Шир Хьюман Дженетик Терапис, Инк. | КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК |
| GR1008018B (el) | 2012-09-06 | 2013-10-29 | Ιδρυμα Ιατροβιολογικων Ερευνων Ακαδημιας Αθηνων, | Λιπιδικα συμπλοκα αποτελουμενα απο ανιονικα λυσο-λιπιδια και η εφαρμογη αυτων |
| CN103296033B (zh) | 2013-05-28 | 2016-05-11 | 京东方科技集团股份有限公司 | 一种阵列基板及其制作方法 |
| EP3019595A4 (en) * | 2013-07-09 | 2016-11-30 | THERAPEUTIC USES OF A GENERIC CHANGE WITH CRISPR / CAS SYSTEMS | |
| BR112016013516A8 (pt) | 2013-12-12 | 2020-05-19 | Life Technologies Corp | complexo de transfecção e seu uso para aumentar transporte de molécula de carga em células e para o tratamento de câncer e terapia gênica, bem como método in vitro para fornecer um poliânion a uma célula |
| EP3169310A1 (en) * | 2014-07-15 | 2017-05-24 | Life Technologies Corporation | Compositions with lipid aggregates and methods for efficient delivery of molecules to cells |
| WO2016205691A1 (en) | 2015-06-19 | 2016-12-22 | Massachusetts Institute Of Technology | Alkenyl substituted 2,5-piperazinediones and their use in compositions for delivering an agent to a subject or cell |
| CN107849567B (zh) * | 2015-06-26 | 2024-07-23 | 苏州瑞博生物技术股份有限公司 | 一种siRNA、含有该siRNA的药物组合物和缀合物及它们的应用 |
| EP3362102A1 (en) | 2015-10-14 | 2018-08-22 | Life Technologies Corporation | Ribonucleoprotein transfection agents |
| US11690921B2 (en) * | 2018-05-18 | 2023-07-04 | Sangamo Therapeutics, Inc. | Delivery of target specific nucleases |
| WO2020051223A1 (en) * | 2018-09-04 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Compositions and methods for organ specific delivery of nucleic acids |
-
2018
- 2018-07-17 LT LTEPPCT/US2018/042555T patent/LT3675826T/lt unknown
- 2018-07-17 AU AU2018324345A patent/AU2018324345B2/en active Active
- 2018-07-17 JP JP2020512589A patent/JP7379325B2/ja active Active
- 2018-07-17 WO PCT/US2018/042555 patent/WO2019045897A1/en not_active Ceased
- 2018-07-17 CA CA3073851A patent/CA3073851A1/en active Pending
- 2018-07-17 US US16/038,107 patent/US20190060482A1/en not_active Abandoned
- 2018-07-17 EP EP18749995.9A patent/EP3675826B1/en active Active
- 2018-07-17 CN CN201880056879.8A patent/CN111065377A/zh active Pending
-
2021
- 2021-07-16 US US17/378,466 patent/US12521447B2/en active Active
-
2023
- 2023-07-14 JP JP2023115742A patent/JP2023138526A/ja active Pending
-
2025
- 2025-12-10 US US19/415,525 patent/US20260108623A1/en active Pending
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