JP2017515901A5 - - Google Patents
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- JP2017515901A5 JP2017515901A5 JP2017511565A JP2017511565A JP2017515901A5 JP 2017515901 A5 JP2017515901 A5 JP 2017515901A5 JP 2017511565 A JP2017511565 A JP 2017511565A JP 2017511565 A JP2017511565 A JP 2017511565A JP 2017515901 A5 JP2017515901 A5 JP 2017515901A5
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- JP
- Japan
- Prior art keywords
- optionally substituted
- compound
- aryl
- heteroaryl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- UKULIMNRHYLACX-UHFFFAOYSA-N O=C(c1ccc[o]1)Nc(cc1)cc2c1nc(NC(c1ccc(cccc3)c3c1)=O)[s]2 Chemical compound O=C(c1ccc[o]1)Nc(cc1)cc2c1nc(NC(c1ccc(cccc3)c3c1)=O)[s]2 UKULIMNRHYLACX-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461991418P | 2014-05-09 | 2014-05-09 | |
| US61/991,418 | 2014-05-09 | ||
| US201562177900P | 2015-03-25 | 2015-03-25 | |
| US62/177,900 | 2015-03-25 | ||
| PCT/US2015/030014 WO2015172099A1 (en) | 2014-05-09 | 2015-05-08 | Anti-viral compounds, pharmaceutical compositions, and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017515901A JP2017515901A (ja) | 2017-06-15 |
| JP2017515901A5 true JP2017515901A5 (https=) | 2018-04-05 |
| JP6419313B2 JP6419313B2 (ja) | 2018-11-07 |
Family
ID=54393071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511565A Expired - Fee Related JP6419313B2 (ja) | 2014-05-09 | 2015-05-08 | 抗ウイルスの化合物、医薬組成物およびその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9884876B2 (https=) |
| EP (1) | EP3139920A4 (https=) |
| JP (1) | JP6419313B2 (https=) |
| CN (1) | CN106456615B (https=) |
| AU (3) | AU2015255714B2 (https=) |
| CA (1) | CA2948178A1 (https=) |
| MX (2) | MX2016014642A (https=) |
| TW (1) | TW201623265A (https=) |
| WO (1) | WO2015172099A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019012295A (es) | 2017-04-14 | 2020-02-07 | Tollnine Inc | Polinucleotidos inmunomoduladores, conjugados de anticuerpos de los mismos y metodos para su uso. |
| TW202021956A (zh) * | 2018-08-09 | 2020-06-16 | 美商奇尼塔公司 | 視黃酸誘導基因"rig-i"途徑之活化劑及其使用方法 |
| CA3051419A1 (en) * | 2018-08-17 | 2020-02-17 | Kineta, Inc. | Activators of the retinoic acid inducible gene "rig-i" pathway and methods of use thereof |
| WO2020089460A1 (en) * | 2018-11-02 | 2020-05-07 | Aicuris Gmbh & Co. Kg | Novel urea 6,7-dihydro-4h-thiazolo[5,4-c]pyridines active against the hepatitis b virus (hbv) |
| BR112021024310A2 (pt) * | 2019-06-05 | 2022-02-15 | Univ Emory | Peptidomiméticos para o tratamento de infecções por coronavírus e picornavírus |
| US20220273689A1 (en) * | 2019-07-09 | 2022-09-01 | Regents Of The University Of Minnesota | Potentiation of antiviral nucleobases as rna virus therapy |
| WO2021067480A1 (en) * | 2019-10-02 | 2021-04-08 | University Of Washington | Compositions and methods for treatment of hepatitis b virus infection |
| CA3169523A1 (en) | 2020-02-28 | 2021-09-02 | Jaume Pons | Transglutaminase-mediated conjugation |
| IL297050A (en) | 2020-04-04 | 2022-12-01 | Pfizer | Methods of treating the 2019 corona virus disease |
| US12358897B2 (en) | 2020-04-05 | 2025-07-15 | Pfizer Inc. | Compounds and method of treating COVID-19 |
| WO2021205296A1 (en) | 2020-04-05 | 2021-10-14 | Pfizer Inc. | Method of treating covid-19 |
| PH12021552872A1 (en) | 2020-04-05 | 2022-03-21 | Pfizer | Compounds and methods for the treatment of covid-19 |
| US20230293716A1 (en) | 2020-05-08 | 2023-09-21 | Bolt Biotherapeutics, Inc. | Elastase-substrate, peptide linker immunoconjugates, and uses thereof |
| WO2021236617A1 (en) | 2020-05-19 | 2021-11-25 | Kallyope, Inc. | Ampk activators |
| CN113831301B (zh) * | 2020-06-08 | 2023-06-06 | 沈阳药科大学 | 苯并噻唑类衍生物及其用途 |
| CN116390925A (zh) | 2020-06-26 | 2023-07-04 | 卡尔优普公司 | Ampk活化剂 |
| JP2023533016A (ja) | 2020-07-11 | 2023-08-01 | ファイザー・インク | 抗ウイルス性ヘテロアリールケトン誘導体 |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| EP4228631B1 (en) * | 2020-10-15 | 2024-08-21 | Baden-Württemberg Stiftung gGmbH | Flavi-block: a pan-flavivirus inhibitor |
| JP2024508817A (ja) * | 2021-02-24 | 2024-02-28 | エフ． ホフマン－ラ ロシュ アーゲー | Ｂ型肝炎ウイルス感染症の処置および予防のためのベンゾチアゾリルビシクロ［１．１．１］ペンタン誘導体 |
| EP4314011A4 (en) * | 2021-03-24 | 2025-01-01 | Anavex Life Sciences Corp. | PREVENTION AND TREATMENT OF CORONAVIRUS INFECTION |
| WO2022208262A1 (en) | 2021-03-30 | 2022-10-06 | Pfizer Inc. | Ether-linked antiviral compounds |
| TWI869780B (zh) | 2022-03-02 | 2025-01-11 | 美商輝瑞大藥廠 | 用於篩檢人類個體之呼吸疾病、監測人類個體之呼吸病況以及提供決策支援之方法及電腦化系統 |
| WO2024149990A1 (en) | 2023-01-10 | 2024-07-18 | Oxford University Innovation Limited | Nirmatrelvir analogs as 3c like protease inhibitors for treating viral infections |
| WO2024252327A1 (en) | 2023-06-09 | 2024-12-12 | Pfizer Inc. | Solid forms of n-(methoxycarbonyl)-3-methyl-l-valyl-(4 r)- n-{(1 s)-1-cyano-2-[(3 s)-2-oxopyrrolidin-3-yl]ethyl}-4-(trifluoromethyl)-l-prolinamide and solvates thereof |
| WO2025037206A1 (en) | 2023-08-11 | 2025-02-20 | Pfizer Inc. | Deuterated antiviral compounds |
| WO2025040743A1 (en) | 2023-08-22 | 2025-02-27 | Univerza V Ljubljani | Conjugated tlr7 and rig-i agonists |
| WO2025191272A1 (en) | 2024-03-13 | 2025-09-18 | Storm Therapeutics Ltd | Inhibitory compounds |
| CN119707862B (zh) * | 2025-02-24 | 2025-06-27 | 北京悦康科创医药科技股份有限公司 | 基于RLRs受体激动剂的疫苗佐剂脂质化合物、包含其的组合物及用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1024316A (en) * | 1911-07-29 | 1912-04-23 | Singer Mfg Co | Strip folding and guiding attachment for sewing-machines. |
| JPS53129036A (en) * | 1977-04-18 | 1978-11-10 | Fuji Photo Film Co Ltd | Color photographic material |
| JPH0780355B2 (ja) * | 1987-01-22 | 1995-08-30 | 富士写真フイルム株式会社 | 光学的情報記録媒体 |
| GB9923710D0 (en) * | 1999-10-08 | 1999-12-08 | Proteus Molecular Design | Chemical compounds |
| WO2004078115A2 (en) * | 2003-02-28 | 2004-09-16 | Viropharma, Incorporated | Benzothiazole compounds, compositions and methods for treatment and prophylaxis of rotavirus infections and associated diseases |
| EP1680431A1 (en) * | 2003-10-17 | 2006-07-19 | Rigel Pharmaceuticals, Inc. | Benzothiazole and thiazole'5,5-b!pyridine compositions and their use as ubiquitin ligase inhibitors |
| WO2009067613A1 (en) * | 2007-11-21 | 2009-05-28 | Abbott Laboratories | Novel compounds as cannabinoid receptor ligands and uses thereof |
| JP2013520502A (ja) * | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| WO2012155352A1 (en) * | 2011-05-19 | 2012-11-22 | Eli Lilly And Company | Dihydroisoxazole compounds, parasiticidal uses and formulations thereof |
| JP2014528412A (ja) * | 2011-09-30 | 2014-10-27 | キネタ・インコーポレイテツド | 抗ウイルス化合物 |
| US9073946B2 (en) * | 2013-01-15 | 2015-07-07 | Kineta, Inc. | Anti-viral compounds |
| CN103193770B (zh) * | 2013-03-20 | 2015-10-28 | 中国人民解放军第二军医大学 | 取代苯并噻唑类抗真菌化合物及其制备方法与应用 |
-
2015
- 2015-05-08 JP JP2017511565A patent/JP6419313B2/ja not_active Expired - Fee Related
- 2015-05-08 EP EP15789075.7A patent/EP3139920A4/en not_active Withdrawn
- 2015-05-08 CN CN201580024136.9A patent/CN106456615B/zh not_active Expired - Fee Related
- 2015-05-08 MX MX2016014642A patent/MX2016014642A/es unknown
- 2015-05-08 TW TW104114809A patent/TW201623265A/zh unknown
- 2015-05-08 WO PCT/US2015/030014 patent/WO2015172099A1/en not_active Ceased
- 2015-05-08 CA CA2948178A patent/CA2948178A1/en not_active Abandoned
- 2015-05-08 AU AU2015255714A patent/AU2015255714B2/en not_active Ceased
- 2015-05-08 US US15/308,058 patent/US9884876B2/en not_active Expired - Fee Related
-
2016
- 2016-11-08 MX MX2020005187A patent/MX2020005187A/es unknown
-
2018
- 2018-01-31 US US15/885,333 patent/US20190002477A1/en not_active Abandoned
-
2020
- 2020-03-12 AU AU2020201815A patent/AU2020201815A1/en not_active Abandoned
- 2020-05-08 US US16/870,208 patent/US20200270274A1/en not_active Abandoned
- 2020-06-29 AU AU2020204324A patent/AU2020204324A1/en not_active Abandoned
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