JP2017514867A5 - - Google Patents

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Publication number
JP2017514867A5
JP2017514867A5 JP2016566786A JP2016566786A JP2017514867A5 JP 2017514867 A5 JP2017514867 A5 JP 2017514867A5 JP 2016566786 A JP2016566786 A JP 2016566786A JP 2016566786 A JP2016566786 A JP 2016566786A JP 2017514867 A5 JP2017514867 A5 JP 2017514867A5
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JP
Japan
Prior art keywords
group
alkyl
optionally substituted
heterocyclyl
compound
Prior art date
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Application number
JP2016566786A
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English (en)
Japanese (ja)
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JP6479854B2 (ja
JP2017514867A (ja
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Publication date
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Priority claimed from PCT/EP2015/059453 external-priority patent/WO2015169677A1/en
Publication of JP2017514867A publication Critical patent/JP2017514867A/ja
Publication of JP2017514867A5 publication Critical patent/JP2017514867A5/ja
Application granted granted Critical
Publication of JP6479854B2 publication Critical patent/JP6479854B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016566786A 2014-05-07 2015-04-30 医薬組成物のためのスルホキシイミン置換キナゾリン Expired - Fee Related JP6479854B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14167373.1 2014-05-07
EP14167373 2014-05-07
PCT/EP2015/059453 WO2015169677A1 (en) 2014-05-07 2015-04-30 Sulfoximine substituted quinazolines for pharmaceutical compositions

Publications (3)

Publication Number Publication Date
JP2017514867A JP2017514867A (ja) 2017-06-08
JP2017514867A5 true JP2017514867A5 (enExample) 2018-09-20
JP6479854B2 JP6479854B2 (ja) 2019-03-06

Family

ID=50639371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016566786A Expired - Fee Related JP6479854B2 (ja) 2014-05-07 2015-04-30 医薬組成物のためのスルホキシイミン置換キナゾリン

Country Status (7)

Country Link
US (1) US10167296B2 (enExample)
EP (1) EP3140300B1 (enExample)
JP (1) JP6479854B2 (enExample)
AU (1) AU2015257917C1 (enExample)
CA (1) CA2944103A1 (enExample)
ES (1) ES2749186T3 (enExample)
WO (1) WO2015169677A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170066778A1 (en) * 2015-09-04 2017-03-09 Aunova Medchem LLC Solubility for target compounds
AU2017239932A1 (en) * 2016-03-31 2018-10-25 Ocean University Of China Method of inhibiting high fat diet-related conditions

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19712960A1 (de) 1997-03-27 1998-10-01 Hoechst Ag Benzyloxy-substituierte, anellierte N-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Bradykininrezeptorantagonisten
SE0102147D0 (sv) 2001-06-18 2001-06-18 Pharmacia Ab New methods
US20050080026A1 (en) 2001-10-29 2005-04-14 Arnd Steuernagel Mnk kinase homologous proteins involved in the regulation of energy homeostasis and organelle metabolism
GB0315587D0 (en) 2003-07-03 2003-08-13 Univ Dundee Anti-inflammatory assay and compounds
ES2611018T3 (es) 2004-04-08 2017-05-04 Dow Agrosciences Llc Sulfoximinas N-sustituidas insecticidas
EP1746099A1 (en) 2004-12-23 2007-01-24 DeveloGen Aktiengesellschaft Mnk1 or Mnk2 inhibitors
EP1899353A1 (en) 2005-06-22 2008-03-19 DeveloGen Aktiengesellschaft Thienopyrimidines for pharmaceutical compositions
KR20080107466A (ko) 2006-03-09 2008-12-10 파마코페이아, 인코포레이티드 대사 장애 치료용 8-헤테로아릴퓨린 ｍｎｋ2 억제제
JP5302883B2 (ja) * 2006-04-07 2013-10-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物用のｍｎｋ１／ｍｎｋ２阻害活性を有するチエノピリミジン
US20080039450A1 (en) 2006-06-22 2008-02-14 Jensen Annika J Compounds
EP1889847A1 (en) * 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
WO2008141843A1 (en) * 2007-05-24 2008-11-27 Bayer Schering Pharma Aktiengesellschaft Novel sulphoximine-substituted quinazoline and quinazoline derivatives as kinase inhibitors
KR20110045019A (ko) * 2008-08-26 2011-05-03 베링거 인겔하임 인터내셔날 게엠베하 약제학적 조성물을 위한 티에노피리미딘
WO2010117425A1 (en) 2009-03-31 2010-10-14 Biogen Idec Ma Inc. Certain substituted pyrimidines, pharmaceutical compositions thereof, and methods for their use
TW201111378A (en) 2009-09-11 2011-04-01 Bayer Schering Pharma Ag Substituted (heteroarylmethyl) thiohydantoins
AR080328A1 (es) * 2010-02-26 2012-03-28 Boehringer Ingelheim Int Tienopirimidinas que contienen un grupo alquilo sustituido inhibidoras de quinasas mnk1 y/o mnk2, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento de trastornos metabolicos tales como diabetes y obesidad, y trastornos hiperproliferativos, entre otros
EA201201191A1 (ru) 2010-02-26 2013-04-30 Бёрингер Ингельхайм Интернациональ Гмбх 4-[циклоалкилокси(гетеро)ариламино]тиено[2,3-d]пиримидины, обладающие ингибирующей активностью по отношению к mnkl/mnk2, предназначенные для фармацевтических композиций
UY33241A (es) * 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
US9170933B2 (en) * 2010-06-28 2015-10-27 International Business Machines Corporation Wear-level of cells/pages/sub-pages/blocks of a memory
AR088082A1 (es) 2011-10-13 2014-05-07 Lilly Co Eli Moduladores selectivos del receptor androgeno
EP2852596B1 (en) 2012-05-21 2016-06-22 Bayer Pharma Aktiengesellschaft Thienopyrimidines
TW201412740A (zh) * 2012-09-20 2014-04-01 Bayer Pharma AG 經取代之吡咯并嘧啶胺基苯并噻唑酮
WO2014048869A1 (en) * 2012-09-26 2014-04-03 Bayer Pharma Aktiengesellschaft Substituted indazol-pyrrolopyrimidines useful in the treatment of hyperproliferative diseases
EP2917185B1 (en) 2012-11-09 2017-05-10 Evotec International GmbH Sulfoximine substituted quinazolines for pharmaceutical compositions
EP2951175B1 (en) * 2013-02-01 2017-10-04 Bayer Pharma Aktiengesellschaft Substituted pyrazolopyrimidinylamino-indazoles
DK3013805T3 (en) * 2013-06-28 2018-04-23 Evotec Int Gmbh Sulfoximine-substituted quinazolines and their use as MNK1 and / or MNK2 kinase inhibitors
AU2014359456B2 (en) * 2013-12-04 2019-01-24 Evotec International Gmbh Sulfoximine substituted quinazolines for pharmaceutical compositions

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