JP2017505622A5 - - Google Patents
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- Publication number
- JP2017505622A5 JP2017505622A5 JP2016549322A JP2016549322A JP2017505622A5 JP 2017505622 A5 JP2017505622 A5 JP 2017505622A5 JP 2016549322 A JP2016549322 A JP 2016549322A JP 2016549322 A JP2016549322 A JP 2016549322A JP 2017505622 A5 JP2017505622 A5 JP 2017505622A5
- Authority
- JP
- Japan
- Prior art keywords
- baff
- seq
- antibody molecule
- chain variable
- variable domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461934124P | 2014-01-31 | 2014-01-31 | |
| US61/934,124 | 2014-01-31 | ||
| PCT/US2015/013711 WO2016039801A1 (en) | 2014-01-31 | 2015-01-30 | Novel anti-baff antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017505622A JP2017505622A (ja) | 2017-02-23 |
| JP2017505622A5 true JP2017505622A5 (enExample) | 2018-03-08 |
| JP6511459B2 JP6511459B2 (ja) | 2019-05-15 |
Family
ID=53754266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549322A Active JP6511459B2 (ja) | 2014-01-31 | 2015-01-30 | 新規な抗baff抗体 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9840543B2 (enExample) |
| EP (1) | EP3099715B1 (enExample) |
| JP (1) | JP6511459B2 (enExample) |
| KR (1) | KR20160113715A (enExample) |
| CN (1) | CN105873949B (enExample) |
| AU (1) | AU2015315834B2 (enExample) |
| BR (1) | BR112016014731A2 (enExample) |
| CA (1) | CA2934965A1 (enExample) |
| CL (1) | CL2016001742A1 (enExample) |
| EA (1) | EA033604B1 (enExample) |
| IL (2) | IL246113B (enExample) |
| MX (1) | MX367661B (enExample) |
| PH (1) | PH12016501366A1 (enExample) |
| WO (1) | WO2016039801A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12022550138A1 (en) | 2013-03-13 | 2023-03-06 | Amgen Inc | Proteins specific for baff and b7rp1 and uses thereof |
| US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
| EA033604B1 (ru) * | 2014-01-31 | 2019-11-08 | Boehringer Ingelheim Int | Молекула анти-baff антитела, фармацевтическая композиция, содержащая эту молекулу, способы ее применения и кодирующий ее изолированный полинуклеотид |
| AU2016297575B2 (en) * | 2015-07-23 | 2021-05-27 | Boehringer Ingelheim International Gmbh | Compound targeting IL-23A and B-cell activating factor (BAFF) and uses thereof |
| WO2017223534A2 (en) * | 2016-06-24 | 2017-12-28 | Anthera Pharmaceuticals, Inc. | Methods of treating iga nephropathy and henoch-schönlein purpura nephritis using a b-cell activating factor (baff) inhibitor |
| WO2018006824A1 (zh) * | 2016-07-06 | 2018-01-11 | 上海开拓者生物医药有限公司 | 一种BLyS抗体及其制备方法和应用 |
| US10869522B2 (en) | 2016-11-04 | 2020-12-22 | Totes Isotoner Corporation | Footwear, and methods of preparing same |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| WO2019136311A2 (en) * | 2018-01-05 | 2019-07-11 | Biograph 55, Inc. | Compositions and methods for cancer immunotherapy |
| WO2019195770A1 (en) | 2018-04-06 | 2019-10-10 | Atyr Pharma, Inc. | Compositions and methods comprising anti-nrp2 antibodies |
| US20210238295A1 (en) * | 2018-04-26 | 2021-08-05 | University Of Virginia Patent Foundation | Compositions and methods for treating abdominal aortic aneurysm |
| AU2020358854A1 (en) | 2019-10-03 | 2022-05-26 | Atyr Pharma, Inc. | Compositions and methods comprising anti-NRP2 antibodies |
| MX2022011335A (es) * | 2020-03-18 | 2022-10-07 | Kindred Biosciences Inc | Anticuerpos del receptor anti-interleucina 4 para uso veterinario. |
| CN113637073B (zh) * | 2020-05-11 | 2024-04-12 | 上海赛比曼生物科技有限公司 | Bcma抗体及其制备和应用 |
| WO2022097061A1 (en) | 2020-11-06 | 2022-05-12 | Novartis Ag | Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies |
| CN112516303A (zh) * | 2020-11-18 | 2021-03-19 | 华中科技大学同济医学院附属协和医院 | Baff抗体在制备脓毒血症药物中的应用 |
| CN116178530A (zh) * | 2021-09-26 | 2023-05-30 | 上海君实生物医药科技股份有限公司 | 抗体在治疗SARS-CoV-2感染的用途 |
| CN118440195B (zh) * | 2022-06-17 | 2025-04-08 | 东莞市朋志生物科技有限公司 | 抗脂联素抗体、检测脂联素的试剂和试剂盒 |
| TW202440636A (zh) | 2023-03-21 | 2024-10-16 | 美商傳記55有限公司 | Cd19/cd38多特異性抗體 |
| TW202544037A (zh) * | 2023-12-11 | 2025-11-16 | 英商葛蘭素史密斯克藍智慧財產發展有限公司 | 抗原結合蛋白 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| WO1981001145A1 (en) | 1979-10-18 | 1981-04-30 | Univ Illinois | Hydrolytic enzyme-activatible pro-drugs |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US4965199A (en) | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| EP0206448B1 (en) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| GB8705477D0 (en) | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
| US4975278A (en) | 1988-02-26 | 1990-12-04 | Bristol-Myers Company | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells |
| DE68925971T2 (de) | 1988-09-23 | 1996-09-05 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| EP0940468A1 (en) | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
| DK0656789T3 (da) | 1992-08-21 | 1998-08-24 | Genentech Inc | Fremgangsmåde til behandling af en LFA-1-medieretforstyrrelse. |
| EP1005870B1 (en) | 1992-11-13 | 2009-01-21 | Biogen Idec Inc. | Therapeutic application of chimeric antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| US6812327B1 (en) * | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| US6037454A (en) | 1996-11-27 | 2000-03-14 | Genentech, Inc. | Humanized anti-CD11a antibodies |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| MXPA01007464A (es) | 1999-01-25 | 2003-06-06 | Apoxis Sa | Baff, inhibidores del mismo y su uso en la modulacion de la respuesta de celula b. |
| DE60143798D1 (de) * | 2000-06-16 | 2011-02-17 | Cambridge Antibody Tech | Immunspezifisch bindende antikörper gegen blys |
| AR035119A1 (es) * | 2001-08-16 | 2004-04-14 | Lilly Co Eli | Anticuerpos humanos antagonistas anti-htnfsf13b |
| WO2006025345A1 (ja) | 2004-08-31 | 2006-03-09 | Kowa Company, Ltd. | 抗ヒトbaff抗体 |
| EP1801231B1 (en) | 2004-09-15 | 2011-11-30 | Kowa Co., Ltd. | Method of screening baff suppressor or inhibitor |
| US8853367B1 (en) | 2004-09-15 | 2014-10-07 | The Uab Research Foundation | Compositions and methods for modulating rank activities |
| WO2007014390A2 (en) * | 2005-07-28 | 2007-02-01 | Biogen Idec Ma Inc. | Methods of targeting baff |
| US8617545B2 (en) | 2005-10-13 | 2013-12-31 | Biogen Idec Ma Inc. | Methods for use with BAFF antagonists |
| WO2008079849A2 (en) | 2006-12-22 | 2008-07-03 | Genentech, Inc. | Antibodies to insulin-like growth factor receptor |
| MX2011000616A (es) | 2008-07-17 | 2011-02-24 | Novartis Ag | Composiciones y metodos de uso para anticuerpos terapeuticos. |
| US20130028897A1 (en) * | 2009-04-27 | 2013-01-31 | Ali Naji | Methods for reducing the level of alloantibodies in a subject |
| WO2011031835A1 (en) | 2009-09-09 | 2011-03-17 | The Uab Research Foundation | Chimeric dr5 polypeptides and uses thereof |
| EP2493507A4 (en) | 2009-10-30 | 2013-11-20 | Merck Sharp & Dohme | AX213 AND AX132 PCSK9 ANTAGONISTS AND VARIANTS THEREOF |
| CA2789071C (en) * | 2010-03-05 | 2018-03-27 | F. Hoffmann-La Roche Ag | Antibodies against human csf-1r and uses thereof |
| MY186903A (en) | 2011-10-28 | 2021-08-26 | Regeneron Pharma | Humanized il-6 and il-6 receptor |
| AR090626A1 (es) | 2012-04-20 | 2014-11-26 | Lilly Co Eli | Anticuerpos anti-baff-anti-il-17 biespecificos |
| US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
| EA033604B1 (ru) * | 2014-01-31 | 2019-11-08 | Boehringer Ingelheim Int | Молекула анти-baff антитела, фармацевтическая композиция, содержащая эту молекулу, способы ее применения и кодирующий ее изолированный полинуклеотид |
-
2015
- 2015-01-30 EA EA201691541A patent/EA033604B1/ru not_active IP Right Cessation
- 2015-01-30 MX MX2016009877A patent/MX367661B/es active IP Right Grant
- 2015-01-30 CN CN201580003487.1A patent/CN105873949B/zh active Active
- 2015-01-30 EP EP15703426.5A patent/EP3099715B1/en active Active
- 2015-01-30 CA CA2934965A patent/CA2934965A1/en not_active Abandoned
- 2015-01-30 WO PCT/US2015/013711 patent/WO2016039801A1/en not_active Ceased
- 2015-01-30 KR KR1020167023947A patent/KR20160113715A/ko not_active Withdrawn
- 2015-01-30 US US14/609,756 patent/US9840543B2/en active Active
- 2015-01-30 AU AU2015315834A patent/AU2015315834B2/en not_active Ceased
- 2015-01-30 JP JP2016549322A patent/JP6511459B2/ja active Active
- 2015-01-30 BR BR112016014731A patent/BR112016014731A2/pt not_active Application Discontinuation
-
2016
- 2016-06-08 IL IL246113A patent/IL246113B/en not_active IP Right Cessation
- 2016-07-07 CL CL2016001742A patent/CL2016001742A1/es unknown
- 2016-07-11 PH PH12016501366A patent/PH12016501366A1/en unknown
-
2017
- 2017-11-06 US US15/803,993 patent/US10377804B2/en active Active
-
2019
- 2019-05-26 IL IL266864A patent/IL266864A/en unknown
- 2019-06-25 US US16/451,333 patent/US11370818B2/en active Active
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