JP2017505329A - 炎症性障害の治療のための新規な塩及びその医薬組成物 - Google Patents

炎症性障害の治療のための新規な塩及びその医薬組成物 Download PDF

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JP2017505329A
JP2017505329A JP2016550633A JP2016550633A JP2017505329A JP 2017505329 A JP2017505329 A JP 2017505329A JP 2016550633 A JP2016550633 A JP 2016550633A JP 2016550633 A JP2016550633 A JP 2016550633A JP 2017505329 A JP2017505329 A JP 2017505329A
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salt
compound
disease
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ルク サボウラウルト ニコラス
ルク サボウラウルト ニコラス
デ ファベリ カルラ
デ ファベリ カルラ
シェイクフ アフマド
シェイクフ アフマド
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Galapagos NV
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
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    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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JP2016550633A 2014-02-07 2015-02-04 炎症性障害の治療のための新規な塩及びその医薬組成物 Pending JP2017505329A (ja)

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GBGB1402071.3A GB201402071D0 (en) 2014-02-07 2014-02-07 Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB1402071.3 2014-02-07
PCT/EP2015/052242 WO2015117981A1 (en) 2014-02-07 2015-02-04 Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders

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JP2017505329A5 JP2017505329A5 (cg-RX-API-DMAC7.html) 2018-03-15

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JP2020011555A Pending JP2020097595A (ja) 2014-02-07 2020-01-28 炎症性障害の治療のための新規な塩及びその医薬組成物

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CN105198878B (zh) * 2015-09-18 2017-07-25 上海宣创生物科技有限公司 一种环丙烷甲酰胺衍生物f晶型及其制备方法
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GB201702603D0 (en) 2017-02-17 2017-04-05 Galápagos Nv Novel compositions and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201808575D0 (en) 2018-05-24 2018-07-11 Galapagos Nv Methods for the treatment of psoriatic arthrits
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WO2020177705A1 (zh) * 2019-03-05 2020-09-10 苏州科睿思制药有限公司 Filgotinib的马来酸盐晶型CSI及其制备方法和用途
BR112021019087A2 (pt) * 2019-03-30 2021-11-30 Unichem Lab Ltd Novo processo para a preparação de filgotinibe e intermediários do mesmo
WO2021044327A1 (en) * 2019-09-03 2021-03-11 Dr. Reddy's Laboratories Limited Solid forms of filgotinib maleate and processes thereof
CN114075188A (zh) * 2020-08-11 2022-02-22 南京柯菲平盛辉制药有限公司 芳香杂环酰胺类化合物及其制备方法和医药用途
JP2023553956A (ja) * 2020-12-09 2023-12-26 セルバトゥス リミテッド 関節の炎症性障害のための併用療法
CN113773322B (zh) * 2021-11-10 2022-02-11 奥锐特药业(天津)有限公司 一种Filgotinib的制备方法

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