JP2017505109A5 - - Google Patents
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- Publication number
- JP2017505109A5 JP2017505109A5 JP2016535242A JP2016535242A JP2017505109A5 JP 2017505109 A5 JP2017505109 A5 JP 2017505109A5 JP 2016535242 A JP2016535242 A JP 2016535242A JP 2016535242 A JP2016535242 A JP 2016535242A JP 2017505109 A5 JP2017505109 A5 JP 2017505109A5
- Authority
- JP
- Japan
- Prior art keywords
- human insect
- seq
- human
- represented
- single chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 241000238631 Hexapoda Species 0.000 claims description 8
- 108090000623 proteins and genes Proteins 0.000 claims description 7
- 239000003053 toxin Substances 0.000 claims description 6
- 231100000765 toxin Toxicity 0.000 claims description 6
- 241000607479 Yersinia pestis Species 0.000 claims description 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 2
- 239000013604 expression vector Substances 0.000 claims description 2
- 239000002917 insecticide Substances 0.000 claims description 2
- 239000002773 nucleotide Substances 0.000 claims description 2
- 125000003729 nucleotide group Chemical group 0.000 claims description 2
- 108700001097 Insect Genes Proteins 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000012636 effector Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000009465 prokaryotic expression Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410037000.9 | 2014-01-26 | ||
| CN201410037000.9A CN103773774B (zh) | 2014-01-26 | 2014-01-26 | 一种人源抗虫基因及其编码的抗Cry1Ab毒素独特型单链抗体与应用 |
| PCT/CN2015/070420 WO2015109951A1 (zh) | 2014-01-26 | 2015-01-09 | 一种人源抗虫基因及其编码的抗Cry1Ab毒素独特型单链抗体与应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017505109A JP2017505109A (ja) | 2017-02-16 |
| JP2017505109A5 true JP2017505109A5 (enExample) | 2017-11-09 |
| JP6236531B2 JP6236531B2 (ja) | 2017-11-22 |
Family
ID=50566539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535242A Expired - Fee Related JP6236531B2 (ja) | 2014-01-26 | 2015-01-09 | ヒト耐虫遺伝子およびそれによりコードされた抗Ｃｒｙ１Ａｂ毒素イディオタイプ一本鎖抗体ならびに用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9751952B2 (enExample) |
| EP (1) | EP3098315B1 (enExample) |
| JP (1) | JP6236531B2 (enExample) |
| CN (1) | CN103773774B (enExample) |
| BR (1) | BR112016016035B1 (enExample) |
| WO (1) | WO2015109951A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103773775B (zh) | 2014-01-26 | 2015-11-18 | 江苏省农业科学院 | 一种人源抗虫基因及其编码的抗Cry1B毒素独特型单链抗体与应用 |
| CN103773774B (zh) | 2014-01-26 | 2015-11-18 | 江苏省农业科学院 | 一种人源抗虫基因及其编码的抗Cry1Ab毒素独特型单链抗体与应用 |
| CN104498501B (zh) * | 2014-12-05 | 2017-07-18 | 江苏省农业科学院 | 一种人源杀虫基因及其编码杀虫肽与应用 |
| CN104628852A (zh) * | 2015-02-04 | 2015-05-20 | 东南大学 | 抗Cry1Ab毒素纳米抗体、其编码序列及应用 |
| CN104926940B (zh) * | 2015-06-15 | 2018-02-09 | 江苏省农业科学院 | 一种人源杀虫蛋白及其制备方法与应用 |
| CN105131123B (zh) * | 2015-09-16 | 2018-11-27 | 江苏省农业科学院 | 一种具有杀虫活性的牛源化改型抗体及其制备方法与应用 |
| CN105085683B (zh) * | 2015-09-16 | 2018-11-27 | 江苏省农业科学院 | 一种具有杀虫活性的猪源化改型抗体及其制备方法与应用 |
| CN105777899B (zh) * | 2016-04-25 | 2021-12-24 | 江苏省农业科学院 | 抗Bt Cry1Ab毒素单克隆抗体及产生该抗体的细胞株、制备方法与应用 |
| CN108101970B (zh) * | 2017-12-14 | 2021-02-26 | 江苏省农业科学院 | 基于抗独特型纳米抗体的Cry1Ab毒素模拟抗原及其应用 |
| CN108997495B (zh) | 2018-08-09 | 2020-08-07 | 江苏省农业科学院 | 一种改进的人源模拟Bt Cry杀虫蛋白功能效应物及其设计方法与应用 |
| CN108997494B (zh) * | 2018-08-09 | 2020-08-07 | 江苏省农业科学院 | 一种改进的人源模拟Bt Cry毒素蛋白功能效应物(GGCC)及其设计方法与应用 |
| CN110294803B (zh) * | 2019-05-27 | 2020-12-01 | 中国农业科学院植物保护研究所 | Cry1Ah1蛋白的单克隆抗体及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006128569A2 (en) | 2005-06-02 | 2006-12-07 | Syngenta Participations Ag | 1143-14a, insecticidal transgenic cotton expressing cry1ab |
| CN102964447A (zh) * | 2012-06-29 | 2013-03-13 | 无锡福阳生物科技有限公司 | 一种Cry1Ab/Ac转基因成分配对单克隆抗体制备及检测方法 |
| CN102936598B (zh) * | 2012-11-21 | 2014-04-16 | 江苏省农业科学院 | 抗Cry1Ac毒素单链抗体的编码基因及免疫PCR检测方法 |
| CN103773774B (zh) | 2014-01-26 | 2015-11-18 | 江苏省农业科学院 | 一种人源抗虫基因及其编码的抗Cry1Ab毒素独特型单链抗体与应用 |
-
2014
- 2014-01-26 CN CN201410037000.9A patent/CN103773774B/zh active Active
-
2015
- 2015-01-09 US US15/104,150 patent/US9751952B2/en active Active
- 2015-01-09 BR BR112016016035-5A patent/BR112016016035B1/pt not_active IP Right Cessation
- 2015-01-09 EP EP15739827.2A patent/EP3098315B1/en not_active Not-in-force
- 2015-01-09 JP JP2016535242A patent/JP6236531B2/ja not_active Expired - Fee Related
- 2015-01-09 WO PCT/CN2015/070420 patent/WO2015109951A1/zh not_active Ceased
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