JP2017504576A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017504576A5 JP2017504576A5 JP2016536162A JP2016536162A JP2017504576A5 JP 2017504576 A5 JP2017504576 A5 JP 2017504576A5 JP 2016536162 A JP2016536162 A JP 2016536162A JP 2016536162 A JP2016536162 A JP 2016536162A JP 2017504576 A5 JP2017504576 A5 JP 2017504576A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- acetamide
- hydroxypropan
- hexafluoro
- cyclopropylmethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13195813 | 2013-12-05 | ||
| EP13195813.4 | 2013-12-05 | ||
| EP14183274 | 2014-09-02 | ||
| EP14183274.1 | 2014-09-02 | ||
| PCT/EP2014/076390 WO2015082533A1 (en) | 2013-12-05 | 2014-12-03 | Ror gamma (rory) modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017504576A JP2017504576A (ja) | 2017-02-09 |
| JP2017504576A5 true JP2017504576A5 (cg-RX-API-DMAC7.html) | 2018-12-27 |
| JP6461960B2 JP6461960B2 (ja) | 2019-01-30 |
Family
ID=52021176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536162A Expired - Fee Related JP6461960B2 (ja) | 2013-12-05 | 2014-12-03 | ＲＯＲガンマ（γ）モジュレータ |
Country Status (29)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3122721A4 (en) * | 2014-03-27 | 2018-01-10 | Piramal Enterprises Limited | Ror-gamma modulators and uses thereof |
| US9718817B2 (en) * | 2014-04-16 | 2017-08-01 | Glenmark Pharmaceuticals S.A. | Aryl and heteroaryl ether compounds as ROR gamma modulators |
| US9861618B2 (en) | 2014-10-30 | 2018-01-09 | Janssen Pharmaceutica Nv | Thiazoles as modulators of RORγt |
| HRP20200016T1 (hr) | 2014-10-30 | 2020-03-20 | Janssen Pharmaceutica Nv | Amidno supstituirani tiazoli kao modulatori rorgamat |
| JOP20200117A1 (ar) | 2014-10-30 | 2017-06-16 | Janssen Pharmaceutica Nv | كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ROR?t |
| HK1249469A1 (zh) | 2015-03-12 | 2018-11-02 | The Regents Of The University Of California | 用RORγ抑制剂治疗癌症的方法 |
| JP6684516B2 (ja) | 2015-05-15 | 2020-04-22 | オーリジーン ディスカバリー テクノロジーズ リミテッドＡｕｒｉｇｅｎｅ Ｄｉｓｃｏｖｅｒｙ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｉｍｉｔｅｄ | Ｒｏｒガンマ調節物質としての置換型テトラヒドロキノリン化合物 |
| WO2016193894A1 (en) * | 2015-05-29 | 2016-12-08 | Glenmark Pharmaceuticals S.A. | Treatment of respiratory disorders using ror- gamma inhibitors |
| EP3101008A1 (en) * | 2015-06-05 | 2016-12-07 | Lead Pharma Cel Models IP B.V. | Ror gamma (rory) modulators |
| EP3101005A1 (en) * | 2015-06-05 | 2016-12-07 | Lead Pharma Cel Models IP B.V. | Ror gamma (rory) modulators |
| WO2017010399A1 (ja) * | 2015-07-10 | 2017-01-19 | 塩野義製薬株式会社 | ＲＯＲγｔ阻害作用を有する化合物およびそれらを含有する医薬組成物 |
| TN2018000188A1 (en) | 2015-12-15 | 2019-10-04 | Astrazeneca Ab | Isoindole compounds |
| TW201803869A (zh) | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為ＲＯＲγＴ調節劑之６－胺基吡啶－３－基噻唑 |
| TW201815388A (zh) * | 2016-07-14 | 2018-05-01 | 印度商卡迪拉保健有限公司 | 作為ＲＯＲγ調節劑之新穎化合物 |
| WO2018011746A1 (en) | 2016-07-14 | 2018-01-18 | Cadila Healthcare Limited | Cyclopropyl derivatives as ror-gamma modulators |
| TWI705958B (zh) * | 2016-12-05 | 2020-10-01 | 荷蘭商領導醫藥控股責任有限公司 | ＲＯＲγ調節子 |
| WO2018116285A1 (en) * | 2016-12-23 | 2018-06-28 | Glenmark Pharmaceuticals S.A. | Substituted morpholine derivatives as ror gamma modulators |
| US11034654B2 (en) | 2017-06-14 | 2021-06-15 | Astrazeneca Ab | 2,3-dihydroisoindole-1-carboxamides useful as ROR-gamma modulators |
| CA3103770A1 (en) | 2018-06-18 | 2019-12-26 | Janssen Pharmaceutica Nv | Phenyl and pyridinyl substituted imidazoles as modulators of roryt |
| CA3103771A1 (en) | 2018-06-18 | 2019-12-26 | Janssen Pharmaceutica Nv | 6-aminopyridin-3-yl pyrazoles as modulators of roryt |
| CN112292373A (zh) | 2018-06-18 | 2021-01-29 | 詹森药业有限公司 | 作为RORγt的调节剂的吡啶基吡唑类 |
| CA3103929A1 (en) | 2018-06-18 | 2019-12-26 | Janssen Pharmaceutica Nv | Phenyl substituted pyrazoles as modulators of roryt |
| EP3921038A1 (en) | 2019-02-06 | 2021-12-15 | Dice Alpha, Inc. | Il-17a modulators and uses thereof |
| JP7566889B2 (ja) * | 2019-09-16 | 2024-10-15 | ダイス・アルファ・インコーポレイテッド | Ｉｌ－１７ａモジュレーターおよびその使用 |
| CN112759541B (zh) * | 2019-10-21 | 2023-03-17 | 复旦大学 | 类吲哚衍生物及其用途 |
| TW202136238A (zh) * | 2020-01-06 | 2021-10-01 | 大陸商廣東東陽光藥業有限公司 | RORγt抑制劑及其製備方法和用途 |
| CN113072521B (zh) * | 2020-01-06 | 2024-04-05 | 广东东阳光药业股份有限公司 | RORγt抑制剂及其在药物中的应用 |
| CN114075139B (zh) * | 2020-08-14 | 2025-09-26 | 广东东阳光药业股份有限公司 | 五元杂芳环类化合物及其在药物中的应用 |
| WO2025157313A1 (zh) * | 2024-01-26 | 2025-07-31 | 上海医药集团股份有限公司 | 一种乙磺酰苯基乙酰胺类化合物的晶型、其制备方法及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011115892A1 (en) * | 2010-03-15 | 2011-09-22 | Griffin Patrick R | Modulators of the retinoic acid receptor-related orphan receptors |
| WO2012027965A1 (en) * | 2010-09-01 | 2012-03-08 | Glaxo Group Limited | Novel compounds |
| WO2013029338A1 (en) * | 2011-09-01 | 2013-03-07 | Glaxo Group Limited | Novel compounds |
| BR112015008515A2 (pt) * | 2012-10-16 | 2017-07-04 | Janssen Pharmaceutica Nv | moduladores de ror t de quinolinila ligada à heteroarila |
| WO2013171729A2 (en) | 2013-01-08 | 2013-11-21 | Glenmark Pharmaceuticals S.A. | Aryl and heteroaryl amide compounds as rorgamat modulator |
| CA2902252A1 (en) * | 2013-03-15 | 2014-09-18 | Monique Bodil Van Niel | Aryl sulfamide and sulfamate derivatives as rorc modulators |
| EP2781217A1 (en) * | 2013-03-18 | 2014-09-24 | ETH Zurich | ROR gamma modulators |
-
2014
- 2014-12-03 AU AU2014359324A patent/AU2014359324B2/en not_active Ceased
- 2014-12-03 MX MX2016007275A patent/MX368721B/es active IP Right Grant
- 2014-12-03 TN TN2016000224A patent/TN2016000224A1/en unknown
- 2014-12-03 CA CA2932483A patent/CA2932483C/en active Active
- 2014-12-03 UA UAA201607189A patent/UA117941C2/uk unknown
- 2014-12-03 PE PE2016000733A patent/PE20160891A1/es unknown
- 2014-12-03 LT LTEP14809794.2T patent/LT3077372T/lt unknown
- 2014-12-03 EP EP14809794.2A patent/EP3077372B8/en active Active
- 2014-12-03 CR CR20160303A patent/CR20160303A/es unknown
- 2014-12-03 PT PT14809794T patent/PT3077372T/pt unknown
- 2014-12-03 ES ES14809794T patent/ES2722409T3/es active Active
- 2014-12-03 WO PCT/EP2014/076390 patent/WO2015082533A1/en not_active Ceased
- 2014-12-03 MY MYPI2016702008A patent/MY179106A/en unknown
- 2014-12-03 PL PL14809794T patent/PL3077372T3/pl unknown
- 2014-12-03 KR KR1020167017849A patent/KR102251128B1/ko active Active
- 2014-12-03 JP JP2016536162A patent/JP6461960B2/ja not_active Expired - Fee Related
- 2014-12-03 RS RS20190494A patent/RS58650B1/sr unknown
- 2014-12-03 HU HUE14809794A patent/HUE043258T2/hu unknown
- 2014-12-03 SI SI201431174T patent/SI3077372T1/sl unknown
- 2014-12-03 HR HRP20190483TT patent/HRP20190483T1/hr unknown
- 2014-12-03 DK DK14809794.2T patent/DK3077372T3/en active
- 2014-12-03 US US15/102,098 patent/US9738600B2/en not_active Expired - Fee Related
- 2014-12-03 EA EA201691173A patent/EA030393B1/ru not_active IP Right Cessation
- 2014-12-03 CN CN201480074695.6A patent/CN105980353B/zh not_active Expired - Fee Related
-
2016
- 2016-06-03 DO DO2016000125A patent/DOP2016000125A/es unknown
- 2016-06-03 PH PH12016501066A patent/PH12016501066A1/en unknown
- 2016-06-03 CL CL2016001364A patent/CL2016001364A1/es unknown
- 2016-06-05 IL IL246018A patent/IL246018B/en active IP Right Grant
- 2016-06-14 ZA ZA2016/04043A patent/ZA201604043B/en unknown