JP2017504311A - 網膜色素上皮細胞を生成する方法 - Google Patents

網膜色素上皮細胞を生成する方法 Download PDF

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JP2017504311A
JP2017504311A JP2016538000A JP2016538000A JP2017504311A JP 2017504311 A JP2017504311 A JP 2017504311A JP 2016538000 A JP2016538000 A JP 2016538000A JP 2016538000 A JP2016538000 A JP 2016538000A JP 2017504311 A JP2017504311 A JP 2017504311A
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rpe
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JP2017504311A5 (enExample
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チャウダリー パールー
チャウダリー パールー
サーマツ−コードレ ベアタ
サーマツ−コードレ ベアタ
ドーン エレン ブース ヘザー
ドーン エレン ブース ヘザー
ジョン ホワイティング ポール
ジョン ホワイティング ポール
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Pfizer Ltd Great Britain
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/15—Transforming growth factor beta (TGF-β)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Neurology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2016538000A 2013-12-11 2014-12-08 網膜色素上皮細胞を生成する方法 Pending JP2017504311A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361914445P 2013-12-11 2013-12-11
US61/914,445 2013-12-11
PCT/IB2014/066703 WO2015087231A1 (en) 2013-12-11 2014-12-08 Method for producing retinal pigment epithelial cells

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JP2017504311A true JP2017504311A (ja) 2017-02-09
JP2017504311A5 JP2017504311A5 (enExample) 2018-01-25

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EP (1) EP3080248A1 (enExample)
JP (1) JP2017504311A (enExample)
KR (1) KR101871084B1 (enExample)
CN (1) CN105814194A (enExample)
AR (1) AR098693A1 (enExample)
AU (1) AU2014363032A1 (enExample)
BR (1) BR112016012129A8 (enExample)
CA (1) CA2933083A1 (enExample)
HK (1) HK1221734A1 (enExample)
IL (1) IL245594A0 (enExample)
MX (1) MX2016007671A (enExample)
TW (2) TW201823451A (enExample)
WO (1) WO2015087231A1 (enExample)

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JP2018501209A (ja) * 2014-11-21 2018-01-18 ライジェル ファーマシューティカルズ， インコーポレイテッド Ｔｇｆ−ベータ阻害剤としての縮合イミダゾール誘導体
WO2021014515A1 (ja) * 2019-07-19 2021-01-28 東京エレクトロン株式会社 細胞の分化状態の評価方法
JP2022532411A (ja) * 2019-05-15 2022-07-14 ノヴォ ノルディスク アー／エス ヒト多能性幹細胞から眼野前駆細胞を得るための方法

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MX2017008818A (es) * 2014-12-30 2018-03-14 Cell Cure Neurosciences Ltd Metodos para tratar enfermedades de la retina.
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KR20170115514A (ko) * 2014-12-30 2017-10-17 셀 큐어 뉴로사이언시스 리미티드 Rpe 세포 집단 및 이를 생성하는 방법
WO2017021973A1 (en) 2015-08-05 2017-02-09 Cell Cure Neurosciences Ltd. Preparation of retinal pigment epithelium cells
EP4001402A1 (en) 2015-09-08 2022-05-25 FUJIFILM Cellular Dynamics, Inc. Macs-based purification of stem cell-derived retinal pigment epithelium
AU2016321170B2 (en) 2015-09-08 2022-09-01 Fujifilm Cellular Dynamics Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells
ES2862676T3 (es) 2015-10-20 2021-10-07 Fujifilm Cellular Dynamics Inc Producción de células precursoras hematopoyéticas multilinaje mediante programación genética
WO2017091844A1 (en) * 2015-12-04 2017-06-08 Bond University Ltd Methods of differentiating retinal cells
CN106344932B (zh) * 2016-08-26 2019-12-27 首都医科大学附属北京同仁医院 一种用于提高视网膜退行性疾病基因治疗效果的组合物及其应用
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CN106906178A (zh) * 2017-04-07 2017-06-30 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 培养上皮细胞的组合物及其保持上皮样细胞形态中的应用
AU2018254442B2 (en) 2017-04-18 2024-03-28 FUJIFILM Cellular Dynamics, Inc. Antigen-specific immune effector cells
WO2018226648A1 (en) * 2017-06-05 2018-12-13 Mayo Foundation For Medical Education And Research Methods and materials for culturing, proliferating, and differentiating stem cells
CN109957545A (zh) 2017-12-26 2019-07-02 江苏艾尔康生物医药科技有限公司 一种消化rpe细胞的方法
TW202012390A (zh) * 2018-06-29 2020-04-01 日商日本歐愛特農業科技股份有限公司 新穎之經取代吡唑衍生物
WO2021020282A1 (ja) 2019-07-26 2021-02-04 学校法人埼玉医科大学 Ａｌｋ２／ａｃｖｒ１の細胞外領域を認識する抗体
CN113699097B (zh) * 2021-09-08 2023-06-09 湖南光琇高新生命科技有限公司 视网膜色素上皮细胞的制备方法

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018501209A (ja) * 2014-11-21 2018-01-18 ライジェル ファーマシューティカルズ， インコーポレイテッド Ｔｇｆ−ベータ阻害剤としての縮合イミダゾール誘導体
JP2022532411A (ja) * 2019-05-15 2022-07-14 ノヴォ ノルディスク アー／エス ヒト多能性幹細胞から眼野前駆細胞を得るための方法
WO2021014515A1 (ja) * 2019-07-19 2021-01-28 東京エレクトロン株式会社 細胞の分化状態の評価方法
JPWO2021014515A1 (enExample) * 2019-07-19 2021-01-28
JP7344421B2 (ja) 2019-07-19 2023-09-14 東京エレクトロン株式会社 細胞の分化状態の評価方法

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BR112016012129A8 (pt) 2020-05-12
WO2015087231A1 (en) 2015-06-18
CN105814194A (zh) 2016-07-27
HK1221734A1 (zh) 2017-06-09
TW201823451A (zh) 2018-07-01
MX2016007671A (es) 2016-10-14
EP3080248A1 (en) 2016-10-19
AR098693A1 (es) 2016-06-08
BR112016012129A2 (pt) 2017-08-08
KR101871084B1 (ko) 2018-06-25
TW201538726A (zh) 2015-10-16
KR20160095118A (ko) 2016-08-10
CA2933083A1 (en) 2015-06-18
AU2014363032A1 (en) 2016-06-09
IL245594A0 (en) 2016-06-30

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