JP2017502300A5 - - Google Patents
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- JP2017502300A5 JP2017502300A5 JP2016543202A JP2016543202A JP2017502300A5 JP 2017502300 A5 JP2017502300 A5 JP 2017502300A5 JP 2016543202 A JP2016543202 A JP 2016543202A JP 2016543202 A JP2016543202 A JP 2016543202A JP 2017502300 A5 JP2017502300 A5 JP 2017502300A5
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- Prior art keywords
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- light
- detector
- optical
- sample
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- 238000000034 method Methods 0.000 claims description 45
- 230000003287 optical effect Effects 0.000 claims description 32
- 238000001514 detection method Methods 0.000 claims description 28
- 239000000835 fiber Substances 0.000 claims description 27
- 230000005284 excitation Effects 0.000 claims description 21
- 230000003595 spectral effect Effects 0.000 claims description 19
- 230000005855 radiation Effects 0.000 claims description 13
- 238000003384 imaging method Methods 0.000 claims description 9
- 239000006185 dispersion Substances 0.000 claims description 8
- 239000013307 optical fiber Substances 0.000 claims description 6
- 230000008878 coupling Effects 0.000 claims description 5
- 238000010168 coupling process Methods 0.000 claims description 5
- 238000005859 coupling reaction Methods 0.000 claims description 5
- 238000001069 Raman spectroscopy Methods 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 230000001427 coherent effect Effects 0.000 claims description 2
- 238000000386 microscopy Methods 0.000 claims description 2
- 230000001443 photoexcitation Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361920654P | 2013-12-24 | 2013-12-24 | |
| US61/920,654 | 2013-12-24 | ||
| PCT/US2014/072368 WO2015100421A1 (en) | 2013-12-24 | 2014-12-24 | Multi-foci multiphoton imaging systems and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017502300A JP2017502300A (ja) | 2017-01-19 |
| JP2017502300A5 true JP2017502300A5 (enExample) | 2018-02-08 |
| JP6596001B2 JP6596001B2 (ja) | 2019-10-23 |
Family
ID=52440818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016543202A Active JP6596001B2 (ja) | 2013-12-24 | 2014-12-24 | 多焦点多光子イメージングシステム及び方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160377546A1 (enExample) |
| EP (1) | EP3087423B1 (enExample) |
| JP (1) | JP6596001B2 (enExample) |
| WO (1) | WO2015100421A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016120434A1 (en) * | 2015-01-31 | 2016-08-04 | Roche Diagnostics Gmbh | Systems and methods for meso-dissection |
| US10788403B2 (en) | 2015-03-11 | 2020-09-29 | Tissuevision, Inc. | Systems and methods for serial staining and imaging |
| EP3426135B1 (en) | 2016-03-08 | 2024-01-03 | Enspectra Health, Inc. | Non-invasive detection of skin disease |
| US10186406B2 (en) * | 2016-03-29 | 2019-01-22 | KLA—Tencor Corporation | Multi-channel photomultiplier tube assembly |
| EP3538940A1 (en) | 2016-11-12 | 2019-09-18 | The Trustees of Columbia University in the City of New York | Microscopy devices, methods and systems |
| US12135261B2 (en) | 2016-11-18 | 2024-11-05 | Tissuevision, Inc. | Automated tissue section capture, indexing and storage system and methods |
| CN106473751B (zh) * | 2016-11-25 | 2024-04-23 | 刘国栋 | 基于阵列式超声传感器的手掌血管成像与识别装置及其成像方法 |
| JP6784603B2 (ja) * | 2017-01-05 | 2020-11-11 | 東レエンジニアリング株式会社 | 分光測定方法および分光測定装置 |
| EP3614915A4 (en) | 2017-04-28 | 2021-01-20 | Enspectra Health, Inc. | SARCOMAS IMAGING AND MEASUREMENT SYSTEMS AND METHODS |
| CN114924401B (zh) * | 2017-06-06 | 2025-04-29 | 美利坚合众国,由健康及人类服务部部长代表 | 显微系统 |
| KR102052414B1 (ko) * | 2018-04-06 | 2019-12-05 | 고려대학교 산학협력단 | 반사 위상 현미경 |
| US11921045B2 (en) * | 2018-07-09 | 2024-03-05 | National University Corporation Kobe University | Holographic three-dimensional multi-spot light stimulation device and method |
| US11231571B2 (en) | 2018-08-09 | 2022-01-25 | Viavi Solutions Inc. | Determining an erroneous movement of a microscope |
| EP3880066A4 (en) | 2018-11-13 | 2022-07-20 | Enspectra Health, Inc. | PROCESSES AND SYSTEMS FOR GENERATION OF DEPTH PROFILES |
| CN109587817B (zh) * | 2018-12-27 | 2020-09-18 | 杭州零域信息技术有限公司 | 一种Wi-Fi信道双网卡深度扫描方案 |
| CN110441311B (zh) * | 2019-07-22 | 2021-10-08 | 中国科学院上海光学精密机械研究所 | 用于多物面成像的多轴多焦镜头 |
| CN115248200A (zh) * | 2021-04-26 | 2022-10-28 | 维林光电(苏州)有限公司 | 多通道激光共聚焦显微探测系统及方法 |
| CN115202022B (zh) * | 2022-08-22 | 2023-03-24 | 浙江荷湖科技有限公司 | 一种各向同性分辨率的扫描光场成像系统和方法 |
| CN115753710B (zh) * | 2022-11-11 | 2025-10-28 | 中国科学院苏州生物医学工程技术研究所 | 一种多焦点扫描与阵列式多通道探测成像方法、设备及介质 |
| CN117129450B (zh) * | 2023-08-10 | 2025-03-07 | 飞秒激光研究中心（广州）有限公司 | 光信号探测系统及其配置方法、飞秒激光影像系统 |
| CN119861474B (zh) * | 2025-03-24 | 2025-07-11 | 中国科学技术大学 | 基于功能性小孔的共聚焦偏振显微成像装置及方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ510096A (en) * | 1998-08-21 | 2003-02-28 | Surromed Inc | Confocal scanning system having spot excitation scanner and light detectors |
| JP3099063B2 (ja) * | 1998-12-28 | 2000-10-16 | 大阪大学長 | 多光子顕微鏡 |
| US6134002A (en) * | 1999-01-14 | 2000-10-17 | Duke University | Apparatus and method for the rapid spectral resolution of confocal images |
| DE10118355B4 (de) * | 2001-04-12 | 2005-07-21 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren und Vorrichtung zur Mehrphotonenanregung einer Probe |
| US7738945B2 (en) * | 2002-04-19 | 2010-06-15 | University Of Washington | Method and apparatus for pseudo-projection formation for optical tomography |
| GB2433319A (en) | 2002-10-23 | 2007-06-20 | Yissum Res Dev Co | In vitro test for studying compound predicting pharmacologic and/or pharmacokinetic and/or pharmacodynamic parameters of a compound |
| JP2005017127A (ja) * | 2003-06-26 | 2005-01-20 | Institute Of Physical & Chemical Research | 干渉計および形状測定装置 |
| US7372985B2 (en) | 2003-08-15 | 2008-05-13 | Massachusetts Institute Of Technology | Systems and methods for volumetric tissue scanning microscopy |
| DE602005007403D1 (de) * | 2004-03-25 | 2008-07-24 | Olympus Corp | Scannendes konfokales Mikroskop |
| JP4593141B2 (ja) * | 2004-03-26 | 2010-12-08 | オリンパス株式会社 | 光走査型観察装置 |
| DE102004034970A1 (de) * | 2004-07-16 | 2006-02-02 | Carl Zeiss Jena Gmbh | Lichtrastermikroskop und Verwendung |
| KR100624454B1 (ko) * | 2004-12-23 | 2006-09-18 | 삼성전기주식회사 | 하이브리드 렌즈 다이 및 하이브리드 렌즈 어레이 |
| US20070057211A1 (en) * | 2005-05-25 | 2007-03-15 | Karsten Bahlman | Multifocal imaging systems and method |
| US7329860B2 (en) * | 2005-11-23 | 2008-02-12 | Illumina, Inc. | Confocal imaging methods and apparatus |
| US7990524B2 (en) * | 2006-06-30 | 2011-08-02 | The University Of Chicago | Stochastic scanning apparatus using multiphoton multifocal source |
| JP2008197127A (ja) * | 2007-02-08 | 2008-08-28 | Olympus Corp | 顕微鏡用対物レンズおよびそれを備えた蛍光検出システムと多光子励起レーザー走査型顕微鏡 |
| EP2171516A1 (en) * | 2007-07-06 | 2010-04-07 | National University of Signapore | Fluorescence focal modulation microscopy system and method |
| JP5536995B2 (ja) * | 2007-07-17 | 2014-07-02 | オリンパス株式会社 | 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム |
| US8194301B2 (en) * | 2008-03-04 | 2012-06-05 | Kla-Tencor Corporation | Multi-spot scanning system and method |
| GB0812712D0 (en) * | 2008-07-10 | 2008-08-20 | Imp Innovations Ltd | Improved endoscope |
| JP5079736B2 (ja) * | 2009-04-20 | 2012-11-21 | ソニー株式会社 | ホログラム再生および撮像装置、ホログラム再生および撮像方法 |
| JP5340799B2 (ja) * | 2009-05-08 | 2013-11-13 | オリンパス株式会社 | レーザ走査型顕微鏡 |
| JP5307629B2 (ja) * | 2009-05-22 | 2013-10-02 | オリンパス株式会社 | 走査型顕微鏡装置 |
| DE102012019121A1 (de) * | 2011-09-29 | 2013-04-04 | Carl Zeiss Microscopy Gmbh | Verfahren zur Variation des Scanfeldes eines Laser-Scanning-Mikroskops |
| JP5831901B2 (ja) * | 2011-11-28 | 2015-12-09 | 国立大学法人大阪大学 | 誘導ラマン散乱顕微鏡 |
| WO2013126762A1 (en) * | 2012-02-23 | 2013-08-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health | Multi-focal structured illumination microscopy systems and methods |
-
2014
- 2014-12-24 JP JP2016543202A patent/JP6596001B2/ja active Active
- 2014-12-24 WO PCT/US2014/072368 patent/WO2015100421A1/en not_active Ceased
- 2014-12-24 EP EP14833432.9A patent/EP3087423B1/en active Active
-
2016
- 2016-06-24 US US15/192,345 patent/US20160377546A1/en active Pending
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