JP2017501211A5 - - Google Patents
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- Publication number
- JP2017501211A5 JP2017501211A5 JP2016552481A JP2016552481A JP2017501211A5 JP 2017501211 A5 JP2017501211 A5 JP 2017501211A5 JP 2016552481 A JP2016552481 A JP 2016552481A JP 2016552481 A JP2016552481 A JP 2016552481A JP 2017501211 A5 JP2017501211 A5 JP 2017501211A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- chain variable
- variable region
- antibody
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 102000004965 antibodies Human genes 0.000 claims 10
- 108090001123 antibodies Proteins 0.000 claims 10
- 102000005614 monoclonal antibodies Human genes 0.000 claims 2
- 108010045030 monoclonal antibodies Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 1
Claims (8)
- ＳＥＱ ＩＤ ＮＯ：９のアミノ酸配列を有する軽鎖可変領域とＳＥＱ ＩＤ ＮＯ：１０のアミノ酸配列を有する重鎖可変領域とを含む、単離された抗体。
- モノクローナル抗体である、請求項１に記載の抗体。
- その配列が、ＳＥＱ ＩＤ ＮＯ：９のアミノ酸配列を有する軽鎖可変領域とＳＥＱ ＩＤ ＮＯ：１０のアミノ酸配列を有する重鎖可変領域とを含む抗体をコードする、核酸。
- ＳＥＱ ＩＤ ＮＯ：９のアミノ酸配列を有する軽鎖可変領域とＳＥＱ ＩＤ ＮＯ：１０のアミノ酸配列を有する重鎖可変領域とを含む抗体を発現する、抗体発現細胞株。
- ＳＥＱ ＩＤ ＮＯ：１１のアミノ酸配列を有する軽鎖可変領域とＳＥＱ ＩＤ ＮＯ：１２のアミノ酸配列を有する重鎖可変領域とを含む、単離された抗体。
- モノクローナル抗体である、請求項５に記載の抗体。
- その配列が、ＳＥＱ ＩＤ ＮＯ：１１のアミノ酸配列を有する軽鎖可変領域とＳＥＱ ＩＤ ＮＯ：１２のアミノ酸配列を有する重鎖可変領域とを含む抗体をコードする、核酸。
- ＳＥＱ ＩＤ ＮＯ：１１のアミノ酸配列を有する軽鎖可変領域とＳＥＱ ＩＤ ＮＯ：１２のアミノ酸配列を有する重鎖可変領域とを含む抗体を発現する、抗体発現細胞株。
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361900942P | 2013-11-06 | 2013-11-06 | |
| US61/900,942 | 2013-11-06 | ||
| US201462054324P | 2014-09-23 | 2014-09-23 | |
| US62/054,324 | 2014-09-23 | ||
| US201462064380P | 2014-10-15 | 2014-10-15 | |
| US62/064,380 | 2014-10-15 | ||
| PCT/US2014/064327 WO2015069880A1 (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019212462A Division JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017501211A JP2017501211A (ja) | 2017-01-12 |
| JP2017501211A5 true JP2017501211A5 (ja) | 2017-11-24 |
Family
ID=53042071
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552481A Pending JP2017501211A (ja) | 2013-11-06 | 2014-11-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2019212462A Pending JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2022003920A Active JP7277623B2 (ja) | 2013-11-06 | 2022-01-13 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2023000938A Pending JP2023052239A (ja) | 2013-11-06 | 2023-01-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019212462A Pending JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2022003920A Active JP7277623B2 (ja) | 2013-11-06 | 2022-01-13 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2023000938A Pending JP2023052239A (ja) | 2013-11-06 | 2023-01-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9822172B2 (ja) |
| EP (2) | EP3066221A4 (ja) |
| JP (4) | JP2017501211A (ja) |
| KR (1) | KR102404285B1 (ja) |
| CN (1) | CN105793439B (ja) |
| AU (1) | AU2014346695B2 (ja) |
| BR (1) | BR112016010106A2 (ja) |
| CA (2) | CA2929547C (ja) |
| EA (1) | EA201690731A1 (ja) |
| HK (1) | HK1221490A1 (ja) |
| MX (1) | MX2016005834A (ja) |
| WO (1) | WO2015069880A1 (ja) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106370857A (zh) | 2008-10-21 | 2017-02-01 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| CN102725636B (zh) | 2009-12-20 | 2015-04-01 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3540440B1 (en) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Methods and uses for evaluating renal injury and renal status |
| CA3158996A1 (en) | 2013-01-17 | 2014-07-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US10300108B2 (en) | 2013-12-03 | 2019-05-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11243202B2 (en) | 2015-04-09 | 2022-02-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| ES2774967T3 (es) | 2015-10-08 | 2020-07-23 | Hoffmann La Roche | IGFBP7 para la predicción del riesgo de LRA cuando se mide antes de una intervención quirúrgica |
| US11243217B2 (en) | 2016-06-06 | 2022-02-08 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| CN110431422A (zh) | 2017-02-06 | 2019-11-08 | 机敏医药股份有限公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| JP7315466B2 (ja) | 2017-04-05 | 2023-07-26 | アスチュート メディカル，インコーポレイテッド | 生体試料中において改善した性能を有する、ｔｉｍｐ２に関するアッセイ |
| BR112020023943A2 (pt) | 2018-05-24 | 2021-02-09 | Renibus Therapeutics, Inc. | métodos de tratamento de pacientes em risco de lesão renal e insuficiência renal |
| WO2020234482A1 (en) * | 2019-05-21 | 2020-11-26 | Universität Zürich | MAPKi RESISTANCE SIGNATURES |
| KR102533791B1 (ko) * | 2022-09-15 | 2023-05-18 | 경북대학교 산학협력단 | 비색법 신호형질 복합체, 이를 이용하는 신장질환 진단용 키트 및 진단법 |
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| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
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| CN105158481A (zh) * | 2010-02-05 | 2015-12-16 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
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-
2014
- 2014-11-06 MX MX2016005834A patent/MX2016005834A/es active IP Right Grant
- 2014-11-06 CA CA2929547A patent/CA2929547C/en active Active
- 2014-11-06 AU AU2014346695A patent/AU2014346695B2/en active Active
- 2014-11-06 JP JP2016552481A patent/JP2017501211A/ja active Pending
- 2014-11-06 EA EA201690731A patent/EA201690731A1/ru unknown
- 2014-11-06 BR BR112016010106A patent/BR112016010106A2/pt not_active Application Discontinuation
- 2014-11-06 WO PCT/US2014/064327 patent/WO2015069880A1/en active Application Filing
- 2014-11-06 US US15/035,205 patent/US9822172B2/en active Active
- 2014-11-06 EP EP14860878.9A patent/EP3066221A4/en not_active Withdrawn
- 2014-11-06 CN CN201480066318.8A patent/CN105793439B/zh active Active
- 2014-11-06 KR KR1020167014700A patent/KR102404285B1/ko active IP Right Grant
- 2014-11-06 EP EP19158290.7A patent/EP3556863A1/en active Pending
- 2014-11-06 CA CA3185700A patent/CA3185700A1/en active Pending
-
2016
- 2016-08-11 HK HK16109610.3A patent/HK1221490A1/zh unknown
-
2017
- 2017-11-20 US US15/818,669 patent/US10562961B2/en active Active
-
2019
- 2019-11-25 JP JP2019212462A patent/JP2020048569A/ja active Pending
-
2020
- 2020-01-17 US US16/745,781 patent/US20200247879A1/en not_active Abandoned
-
2022
- 2022-01-13 JP JP2022003920A patent/JP7277623B2/ja active Active
-
2023
- 2023-01-06 JP JP2023000938A patent/JP2023052239A/ja active Pending
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