JP2017169559A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017169559A5 JP2017169559A5 JP2017037848A JP2017037848A JP2017169559A5 JP 2017169559 A5 JP2017169559 A5 JP 2017169559A5 JP 2017037848 A JP2017037848 A JP 2017037848A JP 2017037848 A JP2017037848 A JP 2017037848A JP 2017169559 A5 JP2017169559 A5 JP 2017169559A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- cell
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 20
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 10
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 210000004962 mammalian cell Anatomy 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 241000699802 Cricetulus griseus Species 0.000 claims 1
- 101150074155 DHFR gene Proteins 0.000 claims 1
- 102100024746 Dihydrofolate reductase Human genes 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 241001529936 Murinae Species 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 108010022394 Threonine synthase Proteins 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 102000004419 dihydrofolate reductase Human genes 0.000 claims 1
- 108020001096 dihydrofolate reductase Proteins 0.000 claims 1
- 238000010494 dissociation reaction Methods 0.000 claims 1
- 230000005593 dissociations Effects 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 201000000050 myeloid neoplasm Diseases 0.000 claims 1
- 108010068617 neonatal Fc receptor Proteins 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492617P | 2011-06-02 | 2011-06-02 | |
| US61/492,617 | 2011-06-02 | ||
| US201161498266P | 2011-06-17 | 2011-06-17 | |
| US61/498,266 | 2011-06-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014513732A Division JP6104897B2 (ja) | 2011-06-02 | 2012-06-01 | Ｆｃレセプター結合タンパク質 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018085040A Division JP6638018B2 (ja) | 2011-06-02 | 2018-04-26 | Ｆｃレセプター結合タンパク質 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2017169559A JP2017169559A (ja) | 2017-09-28 |
| JP2017169559A5 true JP2017169559A5 (enExample) | 2017-12-07 |
| JP6334763B2 JP6334763B2 (ja) | 2018-05-30 |
| JP6334763B6 JP6334763B6 (ja) | 2018-07-11 |
Family
ID=47259886
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014513732A Active JP6104897B2 (ja) | 2011-06-02 | 2012-06-01 | Ｆｃレセプター結合タンパク質 |
| JP2017037848A Active JP6334763B6 (ja) | 2011-06-02 | 2017-03-01 | Ｆｃレセプター結合タンパク質 |
| JP2018085040A Active JP6638018B2 (ja) | 2011-06-02 | 2018-04-26 | Ｆｃレセプター結合タンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014513732A Active JP6104897B2 (ja) | 2011-06-02 | 2012-06-01 | Ｆｃレセプター結合タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018085040A Active JP6638018B2 (ja) | 2011-06-02 | 2018-04-26 | Ｆｃレセプター結合タンパク質 |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US9359438B2 (enExample) |
| EP (2) | EP2714084B1 (enExample) |
| JP (3) | JP6104897B2 (enExample) |
| KR (1) | KR102014554B1 (enExample) |
| CN (2) | CN103619353B (enExample) |
| AU (2) | AU2012262007B2 (enExample) |
| BR (1) | BR112013030352B1 (enExample) |
| CA (1) | CA2837527C (enExample) |
| ES (1) | ES2748583T3 (enExample) |
| IL (1) | IL229618B (enExample) |
| MX (1) | MX343659B (enExample) |
| PH (1) | PH12013502378A1 (enExample) |
| SG (2) | SG195025A1 (enExample) |
| WO (1) | WO2012167039A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI593423B (zh) * | 2008-04-25 | 2017-08-01 | 戴埃克斯有限公司 | Ｆｃ受體結合蛋白 |
| PH12013502378A1 (en) | 2011-06-02 | 2014-01-06 | Dyax Corp | Fc RECEPTOR BINDING PROTEINS |
| GB201208370D0 (en) | 2012-05-14 | 2012-06-27 | Ucb Pharma Sa | Antibodies |
| GB201320066D0 (en) | 2013-11-13 | 2013-12-25 | Ucb Pharma Sa | Biological products |
| JP6620094B2 (ja) * | 2013-11-26 | 2019-12-11 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． | 免疫応答を調節するための組成物および方法 |
| NZ726089A (en) * | 2014-04-30 | 2017-12-22 | Hanall Biopharma Co Ltd | Antibody binding to fcrn for treating autoimmune diseases |
| US10336825B2 (en) | 2014-04-30 | 2019-07-02 | Hanall Biopharma Co., Ltd. | Antibody binding to FcRn for treating autoimmune diseases |
| SG10202007232WA (en) * | 2015-01-30 | 2020-09-29 | Momenta Pharmaceuticals Inc | Fcrn antibodies and methods of use thereof |
| AU2017257680A1 (en) | 2016-04-25 | 2018-12-06 | Syntimmune, Inc. | Humanized affinity matured anti-FcRn antibodies |
| LT3491025T (lt) * | 2016-07-29 | 2023-11-27 | Momenta Pharmaceuticals, Inc. | Fcrn antikūnai ir jų panaudojimo būdai |
| US11787272B2 (en) | 2016-12-01 | 2023-10-17 | Sabic Global Technologies B.V. | Hybrid composite tailgate |
| SG11201911832PA (en) * | 2017-06-15 | 2020-01-30 | UCB Biopharma SRL | Method for the treatment of immune thrombocytopenia |
| MX2020005981A (es) | 2017-12-08 | 2020-08-24 | Argenx Bvba | Uso de antagonistas del fcrn para el tratamiento de la miastenia gravis generalizada. |
| EP3723802A1 (en) * | 2017-12-13 | 2020-10-21 | Momenta Pharmaceuticals, Inc. | Fcrn antibodies and methods of use thereof |
| EP3802590A2 (en) | 2018-06-08 | 2021-04-14 | Argenx BVBA | Compositions and methods for treating immune thrombocytopenia |
| UA130214C2 (uk) * | 2018-07-20 | 2025-12-24 | Момента Фармасьютикалз, Інк. | Фармацевтична композиція антитіл проти fcrn |
| WO2021012176A1 (en) * | 2019-07-23 | 2021-01-28 | Shanghaitech University | Asic1 channel antagonist antibody |
| KR20220148804A (ko) | 2020-01-08 | 2022-11-07 | 아르젠엑스 비브이 | 천포창 장애의 치료 방법 |
| JP2023531451A (ja) | 2020-06-17 | 2023-07-24 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 遺伝子療法患者の治療のための組成物及び方法 |
| WO2022175217A1 (en) * | 2021-02-18 | 2022-08-25 | F. Hoffmann-La Roche Ag | Method for resolving complex, multistep antibody interactions |
| JP2024515620A (ja) * | 2021-04-14 | 2024-04-10 | ジェネンテック， インコーポレイテッド | 生物学的製剤の薬理動態および脳透過性を予測するためのインビトロにおける細胞ベースのアッセイ |
| US20230212316A1 (en) * | 2021-12-15 | 2023-07-06 | Wisconsin Alumni Research Foundation | IgG EPITOPE PEPTIDES THAT BIND RHEUMATOID FACTOR AND METHODS OF USE THEREOF |
| JP2025522251A (ja) | 2022-05-30 | 2025-07-15 | ハナル バイオファーマ カンパニーリミテッド | 安定性が向上した抗ＦｃＲｎ抗体またはこの抗原結合断片 |
| CA3258004A1 (en) | 2022-06-15 | 2023-12-21 | argenx BV | FCRN/HSA BONDING MOLECULES AND METHODS OF USE |
| WO2025099576A1 (en) | 2023-11-06 | 2025-05-15 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating rheumatoid arthritis |
| WO2025163617A1 (en) | 2024-02-04 | 2025-08-07 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating sjögren's disease |
| WO2026083290A1 (en) | 2024-10-16 | 2026-04-23 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating sjögren's disease |
| CN119490588B (zh) * | 2024-10-17 | 2026-03-06 | 广州康盛生物科技股份有限公司 | 一种抗人FcRn的VHH抗体及其应用 |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| US4289747A (en) | 1978-12-26 | 1981-09-15 | E-Y Laboratories, Inc. | Immunological determination using lectin |
| DE2901218A1 (de) | 1979-01-13 | 1980-07-17 | Byk Gulden Lomberg Chem Fab | Ung von theophyllin |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5374548A (en) | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| MX9203291A (es) | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
| US4868103A (en) | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| ATE81724T1 (de) | 1987-11-09 | 1992-11-15 | Becton Dickinson Co | Verfahren zur analyse haematopoietischer zellen in einer probe. |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP0768377A1 (en) | 1988-09-02 | 1997-04-16 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5030002A (en) | 1989-08-11 | 1991-07-09 | Becton, Dickinson And Company | Method and apparatus for sorting particles with a moving catcher tube |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| CA2109602C (en) | 1990-07-10 | 2002-10-01 | Gregory P. Winter | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| IE76732B1 (en) | 1990-08-07 | 1997-11-05 | Becton Dickinson Co | One step test for absolute counts |
| US5179107A (en) | 1990-09-07 | 1993-01-12 | Schering Corporation | Antiviral quinolinone compounds |
| ES2113940T3 (es) | 1990-12-03 | 1998-05-16 | Genentech Inc | Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas. |
| US5370901A (en) | 1991-02-15 | 1994-12-06 | Bracco International B.V. | Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients |
| DE69233769D1 (de) | 1991-03-01 | 2009-09-24 | Dyax Corp | Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon |
| AU662148B2 (en) | 1991-04-10 | 1995-08-24 | Scripps Research Institute, The | Heterodimeric receptor libraries using phagemids |
| ATE255131T1 (de) | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| CA2087413A1 (en) | 1992-01-17 | 1993-07-18 | Joseph R. Lakowicz | Fluorescent energy transfer immunoassay |
| SE9201984D0 (sv) | 1992-06-29 | 1992-06-29 | Pharmacia Biosensor Ab | Improvement in optical assays |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| US6030613A (en) | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| US6086875A (en) | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| ATE549918T1 (de) | 1996-12-03 | 2012-04-15 | Amgen Fremont Inc | Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden |
| DK0971946T3 (da) | 1997-01-21 | 2006-10-30 | Gen Hospital Corp | Selektion af proteiner ved anvendelse af RNA-protein-fusioner |
| WO1998052976A1 (en) | 1997-05-21 | 1998-11-26 | Biovation Limited | Method for the production of non-immunogenic proteins |
| EP1068356B8 (en) | 1998-04-03 | 2007-01-03 | Adnexus Therapeutics, Inc. | Addressable protein arrays |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| EP1051432B1 (en) | 1998-12-08 | 2007-01-24 | Biovation Limited | Method for reducing immunogenicity of proteins |
| US6472147B1 (en) | 1999-05-25 | 2002-10-29 | The Scripps Research Institute | Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| US6960178B2 (en) | 2000-02-02 | 2005-11-01 | Xepmed, Inc. | Apparatus for enhanced plasmapheresis and methods thereof |
| US6992234B2 (en) | 2000-11-06 | 2006-01-31 | The Jackson Laboratory | FcRn-based therapeutics for the treatment of auto-immune disorders |
| WO2003029456A1 (en) | 2001-10-01 | 2003-04-10 | Dyax Corp. | Multi-chain eukaryotic display vectors and uses thereof |
| US20040005709A1 (en) | 2001-10-24 | 2004-01-08 | Hoogenboom Henricus Renerus Jacobus Mattheus | Hybridization control of sequence variation |
| US7498414B2 (en) | 2002-03-04 | 2009-03-03 | Imclone Systems Incorporated | Human antibodies specific to KDR and uses thereof |
| EP1660128A4 (en) | 2003-08-08 | 2009-01-21 | Univ New York State Res Found | ANTI-CORR ANTI-BODIES FOR THE TREATMENT OF AUTO / ALLO-IMMUNE DISORDERS |
| US7662928B2 (en) | 2003-08-08 | 2010-02-16 | The Research Foundation Of State University Of New York | Anti-FcRn antibodies for treatment of auto/allo immune conditions |
| US20100266530A1 (en) | 2005-04-29 | 2010-10-21 | The Jackson Laboratory | FcRN ANTIBODIES AND USES THEREOF |
| JP2009524664A (ja) * | 2006-01-25 | 2009-07-02 | ザ リサーチ ファウンデイション オブ ステイト ユニバーシティー オブ ニューヨーク | 自己／アロ免疫疾患の治療のための抗−ｆｃｒｎ抗体 |
| US20070181136A1 (en) | 2006-02-08 | 2007-08-09 | Gelb Michael L | Oral appliance |
| US8359965B2 (en) | 2007-09-17 | 2013-01-29 | Oxford J Craig | Apparatus and method for broad spectrum radiation attenuation |
| EP3415529B1 (en) | 2007-09-26 | 2020-11-04 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant region |
| AR068723A1 (es) | 2007-10-05 | 2009-12-02 | Glaxo Group Ltd | Proteina que se une a antigenos que se une a il-23 humana y sus usos |
| TWI593423B (zh) * | 2008-04-25 | 2017-08-01 | 戴埃克斯有限公司 | Ｆｃ受體結合蛋白 |
| US8537763B2 (en) | 2008-06-30 | 2013-09-17 | Motorola Mobility Llc | Frame allocation to support legacy wireless communication protocols on uplink transmission |
| EP2322610B1 (en) * | 2008-07-16 | 2016-12-14 | Medical and Biological Laboratories Co., Ltd. | Anti-human clcp1 antibody and use thereof |
| AR074777A1 (es) * | 2008-12-19 | 2011-02-09 | Glaxo Group Ltd | Proteinas de union a antigeno |
| WO2010107110A1 (ja) | 2009-03-19 | 2010-09-23 | 中外製薬株式会社 | 抗体定常領域改変体 |
| PH12013502378A1 (en) | 2011-06-02 | 2014-01-06 | Dyax Corp | Fc RECEPTOR BINDING PROTEINS |
| AU2018281045A1 (en) | 2017-06-05 | 2019-12-12 | Janssen Biotech, Inc. | Engineered multispecific antibodies and other multimeric proteins with asymmetrical CH2-CH3 region mutations |
| EP3802590A2 (en) | 2018-06-08 | 2021-04-14 | Argenx BVBA | Compositions and methods for treating immune thrombocytopenia |
-
2012
- 2012-06-01 PH PH1/2013/502378A patent/PH12013502378A1/en unknown
- 2012-06-01 MX MX2013013832A patent/MX343659B/es active IP Right Grant
- 2012-06-01 SG SG2013085204A patent/SG195025A1/en unknown
- 2012-06-01 CA CA2837527A patent/CA2837527C/en active Active
- 2012-06-01 WO PCT/US2012/040409 patent/WO2012167039A1/en not_active Ceased
- 2012-06-01 KR KR1020137034618A patent/KR102014554B1/ko active Active
- 2012-06-01 JP JP2014513732A patent/JP6104897B2/ja active Active
- 2012-06-01 ES ES12793948T patent/ES2748583T3/es active Active
- 2012-06-01 BR BR112013030352-2A patent/BR112013030352B1/pt active IP Right Grant
- 2012-06-01 AU AU2012262007A patent/AU2012262007B2/en active Active
- 2012-06-01 CN CN201280031902.0A patent/CN103619353B/zh active Active
- 2012-06-01 EP EP12793948.6A patent/EP2714084B1/en active Active
- 2012-06-01 US US14/122,880 patent/US9359438B2/en active Active
- 2012-06-01 CN CN201510926183.4A patent/CN105622754B/zh active Active
- 2012-06-01 EP EP15167896.8A patent/EP2966089B1/en active Active
- 2012-06-01 SG SG10201604493TA patent/SG10201604493TA/en unknown
-
2013
- 2013-11-25 IL IL229618A patent/IL229618B/en active IP Right Grant
-
2016
- 2016-04-27 US US15/139,784 patent/US9862768B2/en active Active
-
2017
- 2017-03-01 JP JP2017037848A patent/JP6334763B6/ja active Active
- 2017-09-21 AU AU2017232160A patent/AU2017232160B2/en active Active
- 2017-12-04 US US15/830,998 patent/US10479834B2/en active Active
-
2018
- 2018-04-26 JP JP2018085040A patent/JP6638018B2/ja active Active
-
2019
- 2019-10-07 US US16/594,218 patent/US11014988B2/en active Active
-
2021
- 2021-03-17 US US17/203,816 patent/US11739152B2/en active Active
-
2023
- 2023-07-06 US US18/347,626 patent/US12454575B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230242651A1 (en) | Stable antibody variable domain framework combinations | |
| JP2020508655A5 (enExample) | ||
| JP2020504101A5 (enExample) | ||
| RU2011116927A (ru) | Антитела против интерлейкина 17 (ил-17) человека и их применение | |
| US20220403028A1 (en) | Novel anti-cd3 antibodies | |
| HRP20201993T1 (hr) | Protutijela protiv pd-1 | |
| PE20200862A1 (es) | Anticuerpos anti-trem2 y metodos relacionados | |
| JP2020519308A5 (enExample) | ||
| FI3322727T3 (fi) | Humanisoituja tai kimeerisiä CD3-vasta-aineita | |
| RU2011153932A (ru) | ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА К Toll-ПОДОБНЫМ РЕЦЕПТОРАМ 2 И ИХ ПРИМЕНЕНИЯ | |
| JP2018121657A5 (enExample) | ||
| FI3561057T3 (fi) | Anti-cd3-vasta-aine ja vasta-ainetta sisältäviä molekyylejä | |
| KR20220029763A (ko) | 신규한 항체 기본구조 | |
| JP2019504617A5 (enExample) | ||
| JP2020524510A5 (enExample) | ||
| JP2012514997A5 (enExample) | ||
| RU2013119957A (ru) | Человеческие антитела к онкостатину м и способы их применения | |
| WO2023193732A1 (zh) | 一种抗ccr8抗体或其抗原结合片段 | |
| RU2012122203A (ru) | Композиции и способы для лечения восполительных нарушений | |
| CN116940598A (zh) | 用于治疗表达cldn18.2的实体瘤的cldn18.2/cd3双特异性抗体 | |
| US20200325214A1 (en) | Novel anti-hsa antibodies | |
| JP2016518333A5 (enExample) | ||
| FI4031569T3 (fi) | Kantasolutekijän vasta-aineet ja niiden käyttömenetelmät | |
| JP2022528387A (ja) | アビド結合多重特異性抗体を作製する方法 | |
| US20150093783A1 (en) | Humanized antibodies to ca215 |