JP2017160268A5 - - Google Patents
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- JP2017160268A5 JP2017160268A5 JP2017123029A JP2017123029A JP2017160268A5 JP 2017160268 A5 JP2017160268 A5 JP 2017160268A5 JP 2017123029 A JP2017123029 A JP 2017123029A JP 2017123029 A JP2017123029 A JP 2017123029A JP 2017160268 A5 JP2017160268 A5 JP 2017160268A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical
- composition
- antiarrhythmic
- administration
- minutes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000203 mixture Substances 0.000 claims 21
- 239000003416 antiarrhythmic agent Substances 0.000 claims 17
- 206010003658 Atrial Fibrillation Diseases 0.000 claims 5
- 210000003748 coronary sinus Anatomy 0.000 claims 5
- 239000000443 aerosol Substances 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 206010003130 Arrhythmia supraventricular Diseases 0.000 claims 2
- 206010003662 Atrial flutter Diseases 0.000 claims 2
- 208000003734 Supraventricular Tachycardia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 230000033764 rhythmic process Effects 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 230000007704 transition Effects 0.000 claims 2
- DJBNUMBKLMJRSA-UHFFFAOYSA-N Flecainide Chemical compound FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(C(=O)NCC2NCCCC2)=C1 DJBNUMBKLMJRSA-UHFFFAOYSA-N 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000001871 Tachycardia Diseases 0.000 claims 1
- 230000003288 anthiarrhythmic effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 206010003119 arrhythmia Diseases 0.000 claims 1
- 230000006793 arrhythmia Effects 0.000 claims 1
- 230000002763 arrhythmic effect Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000002565 electrocardiography Methods 0.000 claims 1
- 229960000449 flecainide Drugs 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000002085 persistent effect Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 210000003492 pulmonary vein Anatomy 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 230000006794 tachycardia Effects 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
- 206010047302 ventricular tachycardia Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21038209P | 2009-03-18 | 2009-03-18 | |
| US61/210,382 | 2009-03-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015149197A Division JP2015193657A (ja) | 2009-03-18 | 2015-07-29 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018204914A Division JP6715305B2 (ja) | 2009-03-18 | 2018-10-31 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017160268A JP2017160268A (ja) | 2017-09-14 |
| JP2017160268A5 true JP2017160268A5 (enExample) | 2017-10-26 |
Family
ID=42739985
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500945A Withdrawn JP2012520890A (ja) | 2009-03-18 | 2010-03-18 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2015149197A Withdrawn JP2015193657A (ja) | 2009-03-18 | 2015-07-29 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2017123029A Pending JP2017160268A (ja) | 2009-03-18 | 2017-06-23 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2018204914A Active JP6715305B2 (ja) | 2009-03-18 | 2018-10-31 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2019162836A Active JP7071949B2 (ja) | 2009-03-18 | 2019-09-06 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500945A Withdrawn JP2012520890A (ja) | 2009-03-18 | 2010-03-18 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2015149197A Withdrawn JP2015193657A (ja) | 2009-03-18 | 2015-07-29 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018204914A Active JP6715305B2 (ja) | 2009-03-18 | 2018-10-31 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2019162836A Active JP7071949B2 (ja) | 2009-03-18 | 2019-09-06 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US8974828B2 (enExample) |
| EP (3) | EP3552603B1 (enExample) |
| JP (5) | JP2012520890A (enExample) |
| AU (1) | AU2010226613B2 (enExample) |
| CA (2) | CA2755809C (enExample) |
| DK (1) | DK2413902T3 (enExample) |
| ES (3) | ES3003038T3 (enExample) |
| PL (1) | PL2413902T3 (enExample) |
| WO (1) | WO2010107964A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3003038T3 (en) | 2009-03-18 | 2025-03-10 | Incarda Therapeutics Inc | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| IL298116A (en) | 2010-12-22 | 2023-01-01 | Syqe Medical Ltd | Method and system for drug delivery |
| US9713687B2 (en) | 2012-08-21 | 2017-07-25 | Philip Morris Usa Inc. | Ventilator aerosol delivery system with transition adapter for introducing carrier gas |
| US11191755B2 (en) | 2014-01-17 | 2021-12-07 | Cornell University | Compositions and methods for providing cardioprotective effects |
| TWI590837B (zh) * | 2014-03-25 | 2017-07-11 | 林信湧 | 一種用於治療心臟病之吸入式醫藥組成物及其備製方法 |
| US10118006B2 (en) | 2014-06-30 | 2018-11-06 | Syqe Medical Ltd. | Methods, devices and systems for pulmonary delivery of active agents |
| CN113616883B (zh) * | 2014-06-30 | 2023-06-06 | Syqe医药有限公司 | 向受试者肺部递送植物材料中的至少一药理活性剂的系统 |
| CN106659858B (zh) | 2014-06-30 | 2020-11-24 | Syqe医药有限公司 | 用于吸入器装置的药物剂量盒 |
| RU2691615C2 (ru) | 2014-06-30 | 2019-06-14 | Сике Медикал Лтд. | Ингалятор с регулированием потока |
| EP3247332A1 (en) * | 2015-01-20 | 2017-11-29 | Incarda Therapeutics, Inc. | Unit aerosol doses for anticoagulation |
| JP6785792B2 (ja) * | 2015-04-14 | 2020-11-18 | マイルストーン ファーマシューティカルズ インコーポレーテッド | 短時間作用性フェニルアルキルアミンカルシウムチャネル遮断薬の高水溶性塩及びその使用 |
| US11806331B2 (en) | 2016-01-06 | 2023-11-07 | Syqe Medical Ltd. | Low dose therapeutic treatment |
| WO2017136421A1 (en) * | 2016-02-01 | 2017-08-10 | Incarda Therapeutics, Inc. | Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation |
| CA3060702A1 (en) * | 2017-05-10 | 2018-11-15 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| US10744087B2 (en) | 2018-03-22 | 2020-08-18 | Incarda Therapeutics, Inc. | Method to slow ventricular rate |
| US20210228825A1 (en) * | 2018-06-05 | 2021-07-29 | Incarda Therapeutics, Inc. | Methods for diagnosing brugada syndrome using an aerosol |
| EP3806839B1 (en) * | 2018-06-14 | 2024-08-07 | Cornell University Cornell Center For Technology, Enterprise & Commercialization ("CCTEC") | Retinoic acid receptor-beta2 agonist with cardioprotective effects |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US11344518B2 (en) * | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| WO2020089890A1 (en) | 2018-10-28 | 2020-05-07 | Syqe Medical Ltd. | Cartridge unit coupler |
| US11007185B2 (en) | 2019-08-01 | 2021-05-18 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
| KR20250171439A (ko) * | 2019-08-01 | 2025-12-08 | 인카다 테라퓨틱스, 인크. | 항부정맥 제제 |
| WO2022133317A1 (en) | 2020-12-17 | 2022-06-23 | Incarda Therapeutics, Inc. | Kits and methods for induction of cardioversion in subjects with atrial arrhythmias |
| CN116867483A (zh) * | 2020-12-17 | 2023-10-10 | 英凯达治疗公司 | 用于诱导患有房性心律失常的对象的心脏复律的试剂盒和方法 |
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-
2010
- 2010-03-18 ES ES19176305T patent/ES3003038T3/es active Active
- 2010-03-18 EP EP19176305.1A patent/EP3552603B1/en active Active
- 2010-03-18 EP EP19176272.3A patent/EP3552602B1/en active Active
- 2010-03-18 US US13/257,249 patent/US8974828B2/en active Active
- 2010-03-18 JP JP2012500945A patent/JP2012520890A/ja not_active Withdrawn
- 2010-03-18 CA CA2755809A patent/CA2755809C/en active Active
- 2010-03-18 CA CA2835771A patent/CA2835771C/en active Active
- 2010-03-18 AU AU2010226613A patent/AU2010226613B2/en active Active
- 2010-03-18 WO PCT/US2010/027740 patent/WO2010107964A1/en not_active Ceased
- 2010-03-18 ES ES10754091T patent/ES2750359T3/es active Active
- 2010-03-18 ES ES19176272T patent/ES3036464T3/es active Active
- 2010-03-18 DK DK10754091.6T patent/DK2413902T3/da active
- 2010-03-18 EP EP10754091.6A patent/EP2413902B1/en active Active
- 2010-03-18 PL PL10754091T patent/PL2413902T3/pl unknown
-
2015
- 2015-02-26 US US14/632,252 patent/US10045939B2/en active Active
- 2015-07-29 JP JP2015149197A patent/JP2015193657A/ja not_active Withdrawn
-
2017
- 2017-06-23 JP JP2017123029A patent/JP2017160268A/ja active Pending
-
2018
- 2018-06-20 US US16/013,178 patent/US20180318213A1/en not_active Abandoned
- 2018-06-20 US US16/013,165 patent/US20180296480A1/en not_active Abandoned
- 2018-10-26 US US16/172,456 patent/US20190060230A1/en not_active Abandoned
- 2018-10-31 JP JP2018204914A patent/JP6715305B2/ja active Active
-
2019
- 2019-09-06 JP JP2019162836A patent/JP7071949B2/ja active Active
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