JP2015193657A5 - - Google Patents

Download PDF

Info

Publication number
JP2015193657A5
JP2015193657A5 JP2015149197A JP2015149197A JP2015193657A5 JP 2015193657 A5 JP2015193657 A5 JP 2015193657A5 JP 2015149197 A JP2015149197 A JP 2015149197A JP 2015149197 A JP2015149197 A JP 2015149197A JP 2015193657 A5 JP2015193657 A5 JP 2015193657A5
Authority
JP
Japan
Prior art keywords
pharmaceutical
composition
antiarrhythmic
amount
antiarrhythmic drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2015149197A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015193657A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2015193657A publication Critical patent/JP2015193657A/ja
Publication of JP2015193657A5 publication Critical patent/JP2015193657A5/ja
Withdrawn legal-status Critical Current

Links

JP2015149197A 2009-03-18 2015-07-29 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 Withdrawn JP2015193657A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21038209P 2009-03-18 2009-03-18
US61/210,382 2009-03-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2012500945A Division JP2012520890A (ja) 2009-03-18 2010-03-18 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017123029A Division JP2017160268A (ja) 2009-03-18 2017-06-23 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法

Publications (2)

Publication Number Publication Date
JP2015193657A JP2015193657A (ja) 2015-11-05
JP2015193657A5 true JP2015193657A5 (enExample) 2016-01-28

Family

ID=42739985

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2012500945A Withdrawn JP2012520890A (ja) 2009-03-18 2010-03-18 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法
JP2015149197A Withdrawn JP2015193657A (ja) 2009-03-18 2015-07-29 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法
JP2017123029A Pending JP2017160268A (ja) 2009-03-18 2017-06-23 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法
JP2018204914A Active JP6715305B2 (ja) 2009-03-18 2018-10-31 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法
JP2019162836A Active JP7071949B2 (ja) 2009-03-18 2019-09-06 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2012500945A Withdrawn JP2012520890A (ja) 2009-03-18 2010-03-18 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2017123029A Pending JP2017160268A (ja) 2009-03-18 2017-06-23 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法
JP2018204914A Active JP6715305B2 (ja) 2009-03-18 2018-10-31 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法
JP2019162836A Active JP7071949B2 (ja) 2009-03-18 2019-09-06 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法

Country Status (9)

Country Link
US (5) US8974828B2 (enExample)
EP (3) EP3552602B1 (enExample)
JP (5) JP2012520890A (enExample)
AU (1) AU2010226613B2 (enExample)
CA (2) CA2835771C (enExample)
DK (1) DK2413902T3 (enExample)
ES (3) ES3003038T3 (enExample)
PL (1) PL2413902T3 (enExample)
WO (1) WO2010107964A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2413902T3 (da) 2009-03-18 2019-10-07 Incarda Therapeutics Inc Enhedsdoser, aerosoler, kits og fremgangsmåder til behandling af hjertetilstande ved pulmonal indgivelse
CA2822738C (en) 2010-12-22 2021-06-08 Exonoid Medical Devices Ltd. Method and system for drug delivery
US9713687B2 (en) 2012-08-21 2017-07-25 Philip Morris Usa Inc. Ventilator aerosol delivery system with transition adapter for introducing carrier gas
US11191755B2 (en) 2014-01-17 2021-12-07 Cornell University Compositions and methods for providing cardioprotective effects
TWI590837B (zh) * 2014-03-25 2017-07-11 林信湧 一種用於治療心臟病之吸入式醫藥組成物及其備製方法
EP3160565B1 (en) * 2014-06-30 2021-08-18 Syqe Medical Ltd. Devices and systems for pulmonary delivery of active agents
BR112016030829B1 (pt) 2014-06-30 2022-02-22 Syqe Medical Ltd Cartucho de dosagem para dispositivo inalador
IL294075A (en) 2014-06-30 2022-08-01 Syqe Medical Ltd Flow regulating inhaler
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
EP3247332A1 (en) * 2015-01-20 2017-11-29 Incarda Therapeutics, Inc. Unit aerosol doses for anticoagulation
KR20240044546A (ko) * 2015-04-14 2024-04-04 마일스톤 파마슈티컬즈 인코포레이티드 단기 작용 페닐알킬아민 칼슘 채널 차단제의 고수용성 염 및 그 용도
CA3009599A1 (en) 2016-01-06 2017-07-13 Syqe Medical Ltd. Low dose therapeutic treatment
SG10202012584UA (en) * 2016-02-01 2021-01-28 Incarda Therapeutics Inc Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
CA3060702A1 (en) * 2017-05-10 2018-11-15 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
EP3768378B1 (en) * 2018-03-22 2025-08-06 InCarda Therapeutics, Inc. A novel method to slow ventricular rate
CN112533664A (zh) * 2018-06-05 2021-03-19 英凯达治疗公司 使用气雾剂诊断Brugada综合征的方法
WO2019241597A1 (en) * 2018-06-14 2019-12-19 Cornell University Compositions and methods for providing cardioprotective effects
US10512620B1 (en) 2018-08-14 2019-12-24 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US11344518B2 (en) 2018-08-14 2022-05-31 AltaThera Pharmaceuticals LLC Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame
US12396970B2 (en) 2021-08-20 2025-08-26 AltaThera Pharmaceuticals LLC Anti-arrhythmic compositions and methods
US11696902B2 (en) 2018-08-14 2023-07-11 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US11610660B1 (en) 2021-08-20 2023-03-21 AltaThera Pharmaceuticals LLC Antiarrhythmic drug dosing methods, medical devices, and systems
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
IL290088B2 (en) * 2019-08-01 2023-10-01 Incarda Therapeutics Inc A pharmaceutical preparation containing flacainide, cyclodextrin and acid, a dosage unit of the preparation and a kit containing the preparation
CN116867483A (zh) * 2020-12-17 2023-10-10 英凯达治疗公司 用于诱导患有房性心律失常的对象的心脏复律的试剂盒和方法
CA3200432A1 (en) * 2020-12-17 2022-06-23 Incarda Therapeutics, Inc. Kits and methods for induction of cardioversion in subjects with atrial arrhythmias

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069819A (en) 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
IT1016489B (it) 1974-03-18 1977-05-30 Isf Spa Inalatore
SE408265B (sv) 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
US4247066A (en) 1978-02-21 1981-01-27 General Dynamics Corporation Airfoil variable cambering device and method
IT1116047B (it) 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
DE3634952A1 (de) 1986-10-14 1988-04-21 Bayer Ag Imidazo-pyrrolo-pyridin-derivate
JP3202705B2 (ja) * 1987-11-06 2001-08-27 リサーチ ディベロップメント ファンデーション 医療用のリポソームおよび薬物含有リポソームのエアゾールの小粒子
US4962095A (en) * 1989-02-15 1990-10-09 E. R. Squibb & Sons, Inc. Method of reducing pre-and post-ischemic myocardial arrhythmias and fibrillation
IT1228459B (it) 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
DE69230613T2 (de) 1991-07-02 2000-12-28 Inhale Inc Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
EP0748213B1 (en) 1994-03-07 2004-04-14 Nektar Therapeutics Methods and compositions for pulmonary delivery of insulin
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
WO1995031479A1 (en) 1994-05-18 1995-11-23 Inhale Therapeutic Systems, Inc. Methods and compositions for the dry powder formulation of interferons
JP3388896B2 (ja) 1994-08-08 2003-03-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
US5693609A (en) 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
KR19980703876A (ko) 1995-04-14 1998-12-05 스티븐 엘. 허스트 분산성이 개선된 분말화된 약학적 조성물
US5985309A (en) 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5855913A (en) 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
JP2001507701A (ja) 1996-12-31 2001-06-12 インヘイル・セラピューティック・システムズ・インコーポレーテッド 親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物
ATE239447T1 (de) 1997-09-29 2003-05-15 Inhale Therapeutic Syst In verneblern verwendbare, stabilisierte zubereitungen
WO1999016420A1 (en) 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in nebulizers
US20020017295A1 (en) 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
US6541479B1 (en) * 1997-12-02 2003-04-01 Massachusetts College Of Pharmacy Calcium channel blockers
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
DE19835346A1 (de) 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
NZ511568A (en) 1998-11-12 2003-08-29 Frank G An inhalation system using lipids for the delivery of bioactive compounds
MXPA01012246A (es) 1999-05-28 2002-08-12 Inhale Therapeutic Syst Aparato y metodo para distribuir una cantidad medida de medicamento en aerosol.
CA2406206C (en) * 2000-04-17 2012-03-20 Vectura Limited Improvements in or relating to formulations for use in inhaler devices
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
WO2001085136A2 (en) 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US6357490B1 (en) 2000-08-22 2002-03-19 Advanced Inhalation Research, Inc. System, method and apparatus for filling containers
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
CA2432319A1 (en) 2000-12-21 2002-07-18 Nektar Therapeutics Pulmonary delivery of polyene antifungal agents
IL157580A0 (en) 2001-03-20 2004-03-28 Glaxo Group Ltd Inhalation drug combination
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
US20070122353A1 (en) * 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
CA2446904A1 (en) * 2001-05-24 2003-04-03 Alexza Pharmaceuticals, Inc. Delivery of drug esters through an inhalation route
US20080038363A1 (en) * 2001-05-24 2008-02-14 Zaffaroni Alejandro C Aerosol delivery system and uses thereof
US7090830B2 (en) * 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
JP4795637B2 (ja) * 2001-09-28 2011-10-19 カーブ テクノロジー，インコーポレイティド 鼻ネブライザー
MXPA04010285A (es) * 2002-04-18 2005-02-03 Cv Therapeutics Inc Metodo para tratar arritmias que comprende la administracion de un agonista de adenosina a1 con un bloqueador beta, bloqueador del canal de calcio o un glucosido cardiaco.
US8245708B2 (en) 2002-05-07 2012-08-21 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
US7607436B2 (en) 2002-05-06 2009-10-27 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
CA2485340C (en) 2002-05-07 2015-09-29 The State University Of New York At Stony Brook Methods, devices and formulations for targeted endobronchial therapy
EP1589947B2 (en) 2002-12-31 2019-01-30 Novartis AG Pharmaceutical formulation with an insoluble active agent for pulmonary administration
EP1633371A1 (en) * 2003-04-24 2006-03-15 Aderis Pharmaceuticals, Inc. Method of treating atrial fibrillation or atrial flutter
WO2005018635A2 (en) * 2003-08-07 2005-03-03 Cardiome Pharma Corp. Ion channel modulating activity i
WO2005112957A1 (en) * 2004-05-21 2005-12-01 Transave, Inc. Treatment of lung diseases and pre-lung disease conditions
US8569277B2 (en) 2004-08-11 2013-10-29 Palo Alto Investors Methods of treating a subject for a condition
TWI396541B (zh) * 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
EP1951672B1 (en) * 2005-10-21 2011-05-25 Merck Sharp & Dohme Corp. Potassium channel inhibitors
ITMI20051999A1 (it) * 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
RU2463085C2 (ru) 2006-10-25 2012-10-10 Новартис Аг Аппарат для распыления порошка, способ его изготовления и применения и его компоненты
JP2010510313A (ja) 2006-11-22 2010-04-02 リライアント・ファーマシューティカルズ・インコーポレイテッド オメガ−３脂肪酸による心房細動の予防および治療
TW200840578A (en) * 2006-12-15 2008-10-16 Procter & Gamble Compositions of azimilide dihydrochloride
US20080275036A1 (en) * 2007-05-02 2008-11-06 Apt Pharmaceuticals, Inc. Prevention and treatment of cardiac conditions
WO2008134630A1 (en) * 2007-04-30 2008-11-06 Apt Pharmaceuticals Dexrazoxane compounds for cardioprotection
WO2010019914A2 (en) 2008-08-14 2010-02-18 The Uab Research Foundation Anti-arrhythmia agents, methods of their use, methods for their identification, and kits thereofre
EP2330895A4 (en) * 2008-08-22 2013-07-31 Milestone Pharmaceuticals Inc BENZOTHIAZEPINE CALCIUM CHANNEL BLOCKER WITH SHORT EFFECT AND ITS USE
KR101689635B1 (ko) * 2008-09-23 2016-12-26 라보라토리 스킨 케어, 인크. 활성제 장입된 균일하고 강성이면서 구형의 나노다공성 인산칼슘 입자 및 그의 제조 방법과 그의 용도
DK2413902T3 (da) 2009-03-18 2019-10-07 Incarda Therapeutics Inc Enhedsdoser, aerosoler, kits og fremgangsmåder til behandling af hjertetilstande ved pulmonal indgivelse

Similar Documents

Publication Publication Date Title
JP2015193657A5 (enExample)
JP2017160268A5 (enExample)
JP2020519628A5 (enExample)
JP2014514271A5 (enExample)
JP2017534604A5 (enExample)
JP2020519628A (ja) 肺投与によって心臓の状態を処置するための単位用量、エアロゾル、キットおよび方法
Verrier et al. Pulmonary delivery of antiarrhythmic drugs for rapid conversion of new-onset atrial fibrillation
JP2016510040A5 (enExample)
JP5501451B2 (ja) 咳の治療のためのテオブロミン
Marum et al. Optimizing flecainide plasma concentration profile for atrial fibrillation conversion while minimizing adverse ventricular effects by rapid, low-dose intratracheal or intravenous administration
TW201002314A (en) Use of dronedarone for the preparation of a medicament for use in the prevention of cardioversion
Paraskevaidis et al. Narrow QRS complex in idiopathic (fascicular) left ventricular tachycardia
WO2024193467A1 (zh) 柏科植物提取物及其在制备心律失常的预防和治疗药物中的应用
Sungnoon et al. Effects of garlic on the induction of ventricular fibrillation
Kaya et al. Adverse Cardiac Effects of Decongestants Agents
Oral et al. Comparison of amiodarone versus ibutilide for the prevention of immediate recurrences of atrial fibrillation during pulmonary vein isolation
Calverley New options for bronchodilator treatment in COPD
EP2905025B1 (en) Use of 1-adamantylethyloxy-3-morpholino-2-propanol or pharmaceutically acceptable salts thereof in pharmaceutical compositions as a neuroretinal protector
Silva et al. Radiofrequency ablation in the treatment of focal atrial fibrillation using circumferential mapping and segmentary disconnection of pulmonary veins
Ipa et al. Combined Efficacy, Safety, and Test Dose Tolerability of Etripamil for Acute Paroxysmal Supraventricular Tachycardia (PSVT) Across Multiple Clinical Trials
Hardy Saxagliptin demonstrates no increased risk for cardiovascular death, heart attack or stroke in the SAVOR cardiovascular outcomes trial: drug trends in cardiology
CN106727610A (zh) 一种治疗病毒性心肌炎的西药组合物及其应用
Halkar et al. Idiopathic Fascicular Ventricular Tachycardia
BONSO et al. Transesophageal Pacing?
Cantarella Bupivacaine/propofol