JP2017108748A5 - - Google Patents
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- JP2017108748A5 JP2017108748A5 JP2017018800A JP2017018800A JP2017108748A5 JP 2017108748 A5 JP2017108748 A5 JP 2017108748A5 JP 2017018800 A JP2017018800 A JP 2017018800A JP 2017018800 A JP2017018800 A JP 2017018800A JP 2017108748 A5 JP2017108748 A5 JP 2017108748A5
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- Prior art keywords
- probe
- tag
- reverse
- labeled
- ligation product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000523 sample Substances 0.000 claims 39
- 238000000034 method Methods 0.000 claims 20
- 230000037452 priming Effects 0.000 claims 10
- 230000007614 genetic variation Effects 0.000 claims 6
- 230000003321 amplification Effects 0.000 claims 5
- 238000003199 nucleic acid amplification method Methods 0.000 claims 5
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- 108060002716 Exonuclease Proteins 0.000 claims 2
- 208000036878 aneuploidy Diseases 0.000 claims 2
- 231100001075 aneuploidy Toxicity 0.000 claims 2
- 102000013165 exonuclease Human genes 0.000 claims 2
- 230000002068 genetic effect Effects 0.000 claims 2
- 238000002372 labelling Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 201000010374 Down Syndrome Diseases 0.000 claims 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 claims 1
- 201000006360 Edwards syndrome Diseases 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000009928 Patau syndrome Diseases 0.000 claims 1
- 206010070863 Toxicity to various agents Diseases 0.000 claims 1
- 206010052779 Transplant rejections Diseases 0.000 claims 1
- 206010044686 Trisomy 13 Diseases 0.000 claims 1
- 208000006284 Trisomy 13 Syndrome Diseases 0.000 claims 1
- 208000007159 Trisomy 18 Syndrome Diseases 0.000 claims 1
- 206010044688 Trisomy 21 Diseases 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 210000003754 fetus Anatomy 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 206010053884 trisomy 18 Diseases 0.000 claims 1
- 208000026485 trisomy X Diseases 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361867554P | 2013-08-19 | 2013-08-19 | |
| US201361867559P | 2013-08-19 | 2013-08-19 | |
| US61/867,554 | 2013-08-19 | ||
| US61/867,559 | 2013-08-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536393A Division JP6088710B2 (ja) | 2013-08-19 | 2014-08-19 | 単分子検出アッセイおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017108748A JP2017108748A (ja) | 2017-06-22 |
| JP2017108748A5 true JP2017108748A5 (enExample) | 2018-02-08 |
| JP6397065B2 JP6397065B2 (ja) | 2018-09-26 |
Family
ID=52484110
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536393A Active JP6088710B2 (ja) | 2013-08-19 | 2014-08-19 | 単分子検出アッセイおよびその使用 |
| JP2017018800A Active JP6397065B2 (ja) | 2013-08-19 | 2017-02-03 | 単分子検出アッセイおよびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536393A Active JP6088710B2 (ja) | 2013-08-19 | 2014-08-19 | 単分子検出アッセイおよびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US9212394B2 (enExample) |
| EP (3) | EP3968023B1 (enExample) |
| JP (2) | JP6088710B2 (enExample) |
| CN (2) | CN105659091A (enExample) |
| AU (2) | AU2014308980C1 (enExample) |
| BR (1) | BR112016003480B1 (enExample) |
| CA (1) | CA2921628A1 (enExample) |
| ES (1) | ES2739430T3 (enExample) |
| IL (3) | IL285521B2 (enExample) |
| MX (2) | MX371428B (enExample) |
| SG (1) | SG11201601201VA (enExample) |
| WO (1) | WO2015026873A1 (enExample) |
| ZA (1) | ZA201601029B (enExample) |
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