JP2016540811A5 - - Google Patents
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- Publication number
- JP2016540811A5 JP2016540811A5 JP2016540686A JP2016540686A JP2016540811A5 JP 2016540811 A5 JP2016540811 A5 JP 2016540811A5 JP 2016540686 A JP2016540686 A JP 2016540686A JP 2016540686 A JP2016540686 A JP 2016540686A JP 2016540811 A5 JP2016540811 A5 JP 2016540811A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- phenyl
- optionally substituted
- oxy
- acetyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361918783P | 2013-12-20 | 2013-12-20 | |
| US61/918,783 | 2013-12-20 | ||
| PCT/IB2014/066707 WO2015092610A1 (en) | 2013-12-20 | 2014-12-08 | N-acylpiperidine ether tropomyosin-related kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016540811A JP2016540811A (ja) | 2016-12-28 |
| JP2016540811A5 true JP2016540811A5 (enExample) | 2017-12-28 |
Family
ID=52440728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540686A Withdrawn JP2016540811A (ja) | 2013-12-20 | 2014-12-08 | Ｎ−アシルピペリジンエーテルトロポミオシン関連キナーゼ阻害剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170305857A1 (enExample) |
| EP (1) | EP3083602A1 (enExample) |
| JP (1) | JP2016540811A (enExample) |
| CA (1) | CA2934010A1 (enExample) |
| WO (1) | WO2015092610A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016009296A1 (en) * | 2014-07-16 | 2016-01-21 | Pfizer Inc. | N-acylpiperidine ether tropomyosin-related kinase inhibitors |
| WO2016020784A1 (en) * | 2014-08-05 | 2016-02-11 | Pfizer Inc. | N-acylpyrrolidine ether tropomyosin-related kinase inhibitors |
| JP2019537585A (ja) | 2016-10-28 | 2019-12-26 | アイカーン スクール オブ メディスン アット マウント シナイ | Ｅｚｈ２媒介性がんを治療するための組成物および方法 |
| WO2019014303A1 (en) * | 2017-07-12 | 2019-01-17 | Bristol-Myers Squibb Company | 5-OR 6,6-CHANNEL BICYCLIC CHAINS AND AMINOHETEROCYCLIC AMINOHETEROCYCLIC INHIBITORS FOR THE TREATMENT OF CARDIAC INSUFFICIENCY |
| JP2021527666A (ja) | 2018-06-21 | 2021-10-14 | アイカーン スクール オブ メディスン アット マウント シナイ | Ｗｄ４０反復ドメインタンパク質５（ｗｄｒ５）分解／破壊化合物および使用の方法 |
| CA3105121A1 (en) * | 2018-07-05 | 2020-01-09 | Icahn School Of Medicine At Mount Sinai | Protein tyrosine kinase 6 (ptk6) degradation / disruption compounds and methods of use |
| CN109970631A (zh) * | 2019-03-26 | 2019-07-05 | 上海吉奉生物科技有限公司 | 一种5-碘-2-吡啶乙酸的合成方法 |
| CN114423463B (zh) | 2019-05-06 | 2025-09-26 | 西奈山伊坎医学院 | 作为hpk1的降解剂的异双功能化合物 |
| US12103924B2 (en) | 2020-06-01 | 2024-10-01 | Icahn School Of Medicine At Mount Sinai | Mitogen-activated protein kinase kinase (MEK) degradation compounds and methods of use |
| CN116396298A (zh) * | 2023-06-06 | 2023-07-07 | 四川维亚本苑生物科技有限公司 | CDK Ligand-1的中间体XII及CDK Ligand-1的制备方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3958002A (en) | 1972-06-20 | 1976-05-18 | Pierre Fabre S.A. | Medicaments having psychotropic properties (antitussives) |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| WO2000035298A1 (en) | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Chewing gum containing medicament active agents |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| UA80171C2 (en) | 2002-12-19 | 2007-08-27 | Pfizer Prod Inc | Pyrrolopyrimidine derivatives |
| BRPI0410654A (pt) * | 2003-06-12 | 2006-06-20 | Novo Nordisk As | composto, composição farmacêutica, uso de um composto, método para tratar um distúrbio de um paciente, e, processo para a preparação de um composto |
| US7417063B2 (en) | 2004-04-13 | 2008-08-26 | Bristol-Myers Squibb Company | Bicyclic heterocycles useful as serine protease inhibitors |
| BRPI0511512A (pt) | 2004-05-27 | 2007-12-26 | Pfizer Prod Inc | derivados pirrolpirimidina úteis no tratamento do cáncer |
| WO2006028029A1 (ja) | 2004-09-07 | 2006-03-16 | Sankyo Company, Limited | 置換ビフェニル誘導体 |
| US8071768B2 (en) * | 2005-06-10 | 2011-12-06 | Janssen Pharmaceutica, N.V. | Alkylquinoline and alkylquinazoline kinase modulators |
| US7405302B2 (en) | 2005-10-11 | 2008-07-29 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB0526107D0 (en) | 2005-12-22 | 2006-02-01 | Angeletti P Ist Richerche Bio | Therapeutic Compounds |
| RU2323058C1 (ru) | 2006-07-12 | 2008-04-27 | ООО Научно-внедренческий центр "Машины и оборудование для энергетики" | Способ формирования наружной резьбы на концевом участке трубной заготовки |
| JPWO2008023720A1 (ja) * | 2006-08-23 | 2010-01-14 | アステラス製薬株式会社 | ウレア化合物又はその塩 |
| US7872018B2 (en) | 2006-12-21 | 2011-01-18 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
| JP5361857B2 (ja) | 2007-03-23 | 2013-12-04 | ファイザー・リミテッド | イオンチャネルの阻害剤 |
| MX2010000617A (es) | 2007-07-17 | 2010-05-17 | Plexxikon Inc | Compuestos y metodos para modulacion de cinasa, e indicaciones de estos. |
| PE20091846A1 (es) | 2008-05-19 | 2009-12-16 | Plexxikon Inc | DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS |
| US8158636B2 (en) | 2008-05-19 | 2012-04-17 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| AU2009257635A1 (en) | 2008-06-10 | 2009-12-17 | Plexxikon, Inc. | 5H-Pyrrolo [2,3-b] pyrazine derivatives for kinase modulation, and indications therefor |
| WO2009152087A1 (en) | 2008-06-10 | 2009-12-17 | Plexxikon, Inc. | Bicyclic heteroaryl compounds and methods for kinase modulation, and indications therefor |
| EA020460B1 (ru) | 2009-01-12 | 2014-11-28 | Пфайзер Лимитед | Производные сульфонамида |
| NZ595910A (en) | 2009-04-29 | 2013-06-28 | Kowa Co | Carbinol compound having heterocyclic linker |
| WO2011021645A1 (ja) * | 2009-08-19 | 2011-02-24 | 大日本住友製薬株式会社 | ２環性ウレア誘導体、またはその薬学的に許容される塩 |
| TWI619713B (zh) | 2010-04-21 | 2018-04-01 | 普雷辛肯公司 | 用於激酶調節的化合物和方法及其適應症 |
| PE20141050A1 (es) | 2011-04-05 | 2014-08-30 | Pfizer Ltd | Inhibidores de quinasa relacionados con pirrolo (2,3-d) pirimidina tropomiosina |
| MY173181A (en) | 2011-05-13 | 2020-01-02 | Array Biopharma Inc | Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as trka kinase inhibitors |
| CA2841757A1 (en) | 2011-07-15 | 2013-01-24 | Etzer Darout | Gpr 119 modulators |
| WO2013088257A1 (en) | 2011-12-12 | 2013-06-20 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic compounds as tropomyosin receptor kinase a (trka) inhibitors |
| EP2842955B1 (en) | 2012-04-26 | 2016-10-05 | ONO Pharmaceutical Co., Ltd. | Trk-inhibiting compound |
-
2014
- 2014-12-08 EP EP14833379.2A patent/EP3083602A1/en not_active Withdrawn
- 2014-12-08 CA CA2934010A patent/CA2934010A1/en not_active Abandoned
- 2014-12-08 JP JP2016540686A patent/JP2016540811A/ja not_active Withdrawn
- 2014-12-08 US US15/101,476 patent/US20170305857A1/en not_active Abandoned
- 2014-12-08 WO PCT/IB2014/066707 patent/WO2015092610A1/en not_active Ceased
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