JP2016533708A5 - - Google Patents
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- Publication number
- JP2016533708A5 JP2016533708A5 JP2016516945A JP2016516945A JP2016533708A5 JP 2016533708 A5 JP2016533708 A5 JP 2016533708A5 JP 2016516945 A JP2016516945 A JP 2016516945A JP 2016516945 A JP2016516945 A JP 2016516945A JP 2016533708 A5 JP2016533708 A5 JP 2016533708A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- oligonucleotide
- ezh2
- detecting
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361888660P | 2013-10-09 | 2013-10-09 | |
| US61/888,660 | 2013-10-09 | ||
| PCT/EP2014/071372 WO2015052147A1 (en) | 2013-10-09 | 2014-10-07 | Methods and compositions for detecting mutation in the human ezh2 gene |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016533708A JP2016533708A (ja) | 2016-11-04 |
| JP2016533708A5 true JP2016533708A5 (cg-RX-API-DMAC7.html) | 2017-11-16 |
| JP6619332B2 JP6619332B2 (ja) | 2019-12-11 |
Family
ID=51663175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016516945A Active JP6619332B2 (ja) | 2013-10-09 | 2014-10-07 | ヒトｅｚｈ２遺伝子中の変異を検出するための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10260102B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3055422B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6619332B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN105593378B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2923706C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2705573T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015052147A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105593378B (zh) | 2013-10-09 | 2019-09-20 | 豪夫迈·罗氏有限公司 | 用于在人ezh2基因中检测突变的方法和组合物 |
| WO2015195848A1 (en) | 2014-06-17 | 2015-12-23 | Epizyme, Inc. | Ezh2 inhibitors for treating lymphoma |
| EP3310372A4 (en) * | 2015-05-19 | 2019-03-06 | Mayo Foundation For Medical Education And Research | METHOD AND MATERIALS FOR PROMOTING BONE TRAINING |
| JP2019500623A (ja) | 2015-11-05 | 2019-01-10 | エピザイム，インコーポレイティド | ヒストンｈ３メチル化ステータスをモニターするためのフローサイトメトリー |
| US11951108B2 (en) * | 2016-01-29 | 2024-04-09 | Epizyme, Inc. | Combination therapy for treating cancer |
| JP2019521988A (ja) | 2016-06-17 | 2019-08-08 | エピザイム，インコーポレイティド | 癌を処置するためのｅｚｈ２阻害剤 |
| CN110730819A (zh) | 2016-10-26 | 2020-01-24 | 索尼克马斯特有限公司 | 肌肉谱系细胞的改善产生及其治疗用途 |
| CN112226513B (zh) * | 2020-10-29 | 2022-02-01 | 华中科技大学 | 一种检测ezh2基因可变剪切位点突变的引物、试剂盒及应用 |
| CN120624641A (zh) * | 2025-02-20 | 2025-09-12 | 宁波熙宁检测技术有限公司 | 一种用于检测ezh2基因突变的核酸组合物、试剂盒及检测方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981176A (en) | 1992-06-17 | 1999-11-09 | City Of Hope | Method of detecting and discriminating between nucleic acid sequences |
| EP0866071B1 (en) | 1997-03-20 | 2004-10-20 | F. Hoffmann-La Roche Ag | Modified primers |
| WO2001042498A1 (en) | 1999-12-10 | 2001-06-14 | Toyo Boseki Kabushiki Kaisha | Method of detecting nucleotide polymorphism |
| WO2005005601A2 (en) * | 2003-06-09 | 2005-01-20 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| JP2009247231A (ja) * | 2008-04-02 | 2009-10-29 | Olympus Corp | 標的塩基判別方法 |
| ES2527653T3 (es) | 2008-10-20 | 2015-01-28 | F. Hoffmann-La Roche Ag | Amplificación específica de alelo usando un cebador con un nucleótido modificado |
| US20100143901A1 (en) | 2008-12-09 | 2010-06-10 | Roche Molecular Systems, Inc. | Nuclease-Free Real-Time Detection of Nucleic Acids |
| CN101993934A (zh) | 2009-08-10 | 2011-03-30 | 芮屈生物技术（上海）有限公司 | 一种ezh2基因的原位杂交检测试剂盒及其检测方法和应用 |
| US9730925B2 (en) | 2011-09-30 | 2017-08-15 | Glaxomithkline Llc | Methods of treating cancer |
| WO2013086639A1 (en) * | 2011-12-14 | 2013-06-20 | British Columbia Cancer Agency Branch | Mutations indicative of weaver syndrome |
| CN105593378B (zh) | 2013-10-09 | 2019-09-20 | 豪夫迈·罗氏有限公司 | 用于在人ezh2基因中检测突变的方法和组合物 |
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2014
- 2014-10-07 CN CN201480055312.0A patent/CN105593378B/zh active Active
- 2014-10-07 EP EP14781520.3A patent/EP3055422B1/en active Active
- 2014-10-07 US US14/508,618 patent/US10260102B2/en active Active
- 2014-10-07 WO PCT/EP2014/071372 patent/WO2015052147A1/en not_active Ceased
- 2014-10-07 ES ES14781520T patent/ES2705573T3/es active Active
- 2014-10-07 CA CA2923706A patent/CA2923706C/en active Active
- 2014-10-07 JP JP2016516945A patent/JP6619332B2/ja active Active