JP2016533708A5 - - Google Patents

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Publication number
JP2016533708A5
JP2016533708A5 JP2016516945A JP2016516945A JP2016533708A5 JP 2016533708 A5 JP2016533708 A5 JP 2016533708A5 JP 2016516945 A JP2016516945 A JP 2016516945A JP 2016516945 A JP2016516945 A JP 2016516945A JP 2016533708 A5 JP2016533708 A5 JP 2016533708A5
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JP
Japan
Prior art keywords
nucleic acid
oligonucleotide
ezh2
detecting
mutation
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JP2016516945A
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English (en)
Japanese (ja)
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JP6619332B2 (ja
JP2016533708A (ja
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Priority claimed from PCT/EP2014/071372 external-priority patent/WO2015052147A1/en
Publication of JP2016533708A publication Critical patent/JP2016533708A/ja
Publication of JP2016533708A5 publication Critical patent/JP2016533708A5/ja
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Publication of JP6619332B2 publication Critical patent/JP6619332B2/ja
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JP2016516945A 2013-10-09 2014-10-07 ヒトezh2遺伝子中の変異を検出するための方法及び組成物 Active JP6619332B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361888660P 2013-10-09 2013-10-09
US61/888,660 2013-10-09
PCT/EP2014/071372 WO2015052147A1 (en) 2013-10-09 2014-10-07 Methods and compositions for detecting mutation in the human ezh2 gene

Publications (3)

Publication Number Publication Date
JP2016533708A JP2016533708A (ja) 2016-11-04
JP2016533708A5 true JP2016533708A5 (OSRAM) 2017-11-16
JP6619332B2 JP6619332B2 (ja) 2019-12-11

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JP2016516945A Active JP6619332B2 (ja) 2013-10-09 2014-10-07 ヒトezh2遺伝子中の変異を検出するための方法及び組成物

Country Status (7)

Country Link
US (1) US10260102B2 (OSRAM)
EP (1) EP3055422B1 (OSRAM)
JP (1) JP6619332B2 (OSRAM)
CN (1) CN105593378B (OSRAM)
CA (1) CA2923706C (OSRAM)
ES (1) ES2705573T3 (OSRAM)
WO (1) WO2015052147A1 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015052147A1 (en) 2013-10-09 2015-04-16 Roche Diagnostics Gmbh Methods and compositions for detecting mutation in the human ezh2 gene
SG10201811128RA (en) 2014-06-17 2019-01-30 Epizyme Inc Ezh2 inhibitors for treating lymphoma
EP3310372A4 (en) * 2015-05-19 2019-03-06 Mayo Foundation For Medical Education And Research METHOD AND MATERIALS FOR PROMOTING BONE TRAINING
WO2017079738A1 (en) 2015-11-05 2017-05-11 Epizyme, Inc. Flow cytometry for monitoring histone h3 methylation status
WO2017132518A1 (en) * 2016-01-29 2017-08-03 Epizyme, Inc. Combination therapy for treating cancer
WO2017218953A1 (en) 2016-06-17 2017-12-21 Epizyme, Inc. Ezh2 inhibitors for treating cancer
AU2017351638A1 (en) 2016-10-26 2019-06-13 Genea Biocells USA (Holdings), Inc. Improved generation of muscle lineage cells and therapeutic uses thereof
CN112226513B (zh) * 2020-10-29 2022-02-01 华中科技大学 一种检测ezh2基因可变剪切位点突变的引物、试剂盒及应用
CN119662835B (zh) * 2025-02-20 2025-05-27 宁波熙宁检测技术有限公司 一种用于检测ezh2基因突变的核酸组合物、试剂盒及检测方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981176A (en) 1992-06-17 1999-11-09 City Of Hope Method of detecting and discriminating between nucleic acid sequences
EP0866071B1 (en) 1997-03-20 2004-10-20 F. Hoffmann-La Roche Ag Modified primers
WO2001042498A1 (en) 1999-12-10 2001-06-14 Toyo Boseki Kabushiki Kaisha Method of detecting nucleotide polymorphism
KR20060031809A (ko) * 2003-06-09 2006-04-13 더 리젠츠 오브 더 유니버시티 오브 미시간 암 치료 및 진단용 조성물 및 방법
JP2009247231A (ja) * 2008-04-02 2009-10-29 Olympus Corp 標的塩基判別方法
ES2527653T3 (es) 2008-10-20 2015-01-28 F. Hoffmann-La Roche Ag Amplificación específica de alelo usando un cebador con un nucleótido modificado
US20100143901A1 (en) 2008-12-09 2010-06-10 Roche Molecular Systems, Inc. Nuclease-Free Real-Time Detection of Nucleic Acids
CN101993934A (zh) 2009-08-10 2011-03-30 芮屈生物技术(上海)有限公司 一种ezh2基因的原位杂交检测试剂盒及其检测方法和应用
US9730925B2 (en) 2011-09-30 2017-08-15 Glaxomithkline Llc Methods of treating cancer
WO2013086639A1 (en) * 2011-12-14 2013-06-20 British Columbia Cancer Agency Branch Mutations indicative of weaver syndrome
WO2015052147A1 (en) 2013-10-09 2015-04-16 Roche Diagnostics Gmbh Methods and compositions for detecting mutation in the human ezh2 gene

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